公开(公告)号：US20230073214A1

公开(公告)日：2023-03-09

申请号：US17945585

申请日：2022-09-15

Applicant: DexCom, Inc.

Inventor： Shanger Wang ,  Mahender Nath Avula ,  Chris Dring ,  Ted Tang Lee ,  Xiangyou Liu ,  Shane Richard Parnell ,  Jiong Zou

IPC: A61K9/00 ,  A61B5/145 ,  A61B5/1486 ,  A61K31/573

Abstract: The present disclosure relates generally to bioactive releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel bioactive releasing membranes, to devices and implantable devices including these membranes, methods for forming the bioactive releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

公开(公告)号：US20230067282A1

公开(公告)日：2023-03-02

申请号：US17984100

申请日：2022-11-09

Applicant: DexCom, Inc

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/145 ,  G01N27/327 ,  A61B5/1459 ,  G01N33/66 ,  A61B5/1495 ,  A61B5/00 ,  A61M15/00 ,  G16H20/17 ,  G16H40/63 ,  A61M5/142 ,  A61M5/172 ,  A61M5/20 ,  A61M11/00 ,  A61M35/00 ,  H05K3/32

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20220338762A1

公开(公告)日：2022-10-27

申请号：US17861872

申请日：2022-07-11

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/145 ,  G01N27/327 ,  A61B5/1459 ,  G01N33/66 ,  A61B5/1495 ,  A61B5/00 ,  A61M15/00 ,  G16H20/17 ,  G16H40/63 ,  A61M5/142 ,  A61M5/172 ,  A61M5/20 ,  A61M11/00 ,  A61M35/00 ,  H05K3/32

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20220296867A1

公开(公告)日：2022-09-22

申请号：US17697701

申请日：2022-03-17

Applicant: DexCom, Inc.

Inventor： Mahender Nath Avula ,  Chris Dring ,  Ted Tang Lee ,  Xiangyou Liu ,  Shane Richard Parnell ,  Shanger Wang ,  Jiong Zou

IPC: A61M31/00 ,  A61B5/145

Abstract: The present disclosure relates generally to drug releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel drug releasing membranes, to devices and implantable devices including these membranes, methods for forming the drug releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

公开(公告)号：US20220104773A1

公开(公告)日：2022-04-07

申请号：US17544551

申请日：2021-12-07

Applicant: DexCom, Inc.

Inventor： James Jinwoo Lee ,  Leif N. Bowman ,  Tim Ray Gackstetter ,  Jonathan Hughes ,  Jeff Jackson ,  Ted Tang Lee ,  Phong Lieu ,  Andrew Attila Pal ,  James R. Petisce ,  Jack Pryor ,  Roger Schneider ,  Peter C. Simpson ,  George Vigil ,  Matthew D. Wightlin

IPC: A61B5/00 ,  A61B5/145

Abstract: Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

公开(公告)号：US20210330885A1

公开(公告)日：2021-10-28

申请号：US17369535

申请日：2021-07-07

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61M11/00 ,  A61M15/00 ,  G16H40/63 ,  G16H20/17 ,  A61M35/00 ,  A61M5/20

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20210290122A1

公开(公告)日：2021-09-23

申请号：US17333782

申请日：2021-05-28

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US11112377B2

公开(公告)日：2021-09-07

申请号：US15394520

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Shanger Wang ,  Ted Tang Lee ,  Jiong Zou

IPC: G01N27/327 ,  C12Q1/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  G01N33/66 ,  C08G18/08 ,  C08G18/48 ,  C08G18/40 ,  C08G18/38 ,  C08G18/12 ,  C08G18/44 ,  C08G18/75 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  A61B5/1473 ,  C12N11/08

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

公开(公告)号：US10827955B2

公开(公告)日：2020-11-10

申请号：US15798064

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  John Patrick Majewski ,  Maria Noel Brown Wells ,  Leah Morta Edra ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US20170191955A1

公开(公告)日：2017-07-06

申请号：US15394694

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Jiong Zou ,  Robert J. Boock ,  Andrew Trinin Dennis ,  Ted Tang Lee ,  Jeff T. Suri ,  David Sze ,  Mark A. Tapsak ,  Huashi Zhang ,  Shanger Wang

IPC: G01N27/327 ,  C08L69/00 ,  C08L75/04 ,  C12Q1/00 ,  C08L39/06

CPC classification number: G01N27/3273 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/12 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  C08G18/0828 ,  C08G18/12 ,  C08G18/3857 ,  C08G18/4018 ,  C08G18/44 ,  C08G18/4833 ,  C08G18/755 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  C12N11/08 ,  C12Q1/002 ,  C12Q1/006 ,  G01N27/3275 ,  G01N33/66 ,  C08G18/3234

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.