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公开(公告)号:US20060052669A1
公开(公告)日:2006-03-09
申请号:US10539641
申请日:2004-01-20
申请人: Charles Hart
发明人: Charles Hart
IPC分类号: A61B1/32
CPC分类号: A61B17/0218 , A61B1/32 , A61B17/0293 , A61B2017/0212 , A61B2017/2931
摘要: A positionable internal retraction device is provided comprising a malleable ring member and a web-like structure. The retraction device operates to temporarily reposition tissues and organs from an operative site to provide a clear access and visual path for the surgeon. The ring member may be elongated, twisted, folded, bent or deformed to provide an appropriate insertion profile and subsequent functional shape. The retraction device may be shaped for both open and minimally invasive surgeries. The retraction device is atraumatic and may be used for retraction of delicate tissues and organs. The ring member may have different bending biases. The web-like structure may be constructed of any elastic material that can stretch and recover from the shaping and reshaping of the ring member. In another aspect of the invention, the ring member further comprises an internal lumen defining a wall, which may be of any geometric shape providing a desired bending bias. The ring member may further include a reinforcement member placed within the lumen and made of a “shape memory” material that allows the reinforcement member to return to its desired shape or condition after being bent. The reinforcement member may be placed in some sections of the ring member to keep these sections substantially straight. Each of the ring member, the reinforcement member and the internal wall may have a cross-section or profile of any geometric shape to provide a desired bending bias in a preferred plane. In yet another aspect of the invention, the ring member further comprises a second lumen and a second reinforcement member placed within the second lumen to provide a desired bending bias.
摘要翻译: 提供了一种可定位的内部回缩装置,其包括可延展的环构件和网状结构。 缩回装置用于暂时从手术部位重新定位组织和器官,以为外科医生提供清晰的通路和视觉路径。 环形构件可以是细长的,扭曲的,折叠的,弯曲的或变形的,以提供适当的插入轮廓和随后的功能形状。 缩回装置可以成形为开放和微创手术。 收缩装置无创伤,可用于收缩精细的组织和器官。 环件可能具有不同的弯曲偏差。 网状结构可以由能够从环构件的成形和整形拉伸和恢复的任何弹性材料构成。 在本发明的另一方面,环形构件还包括限定壁的内腔,所述壁可具有提供期望的弯曲偏压的任何几何形状。 环构件还可以包括放置在内腔内并由“形状记忆”材料制成的加强构件,其允许加强构件在弯曲之后返回到其期望的形状或状态。 加强构件可以放置在环构件的一些部分中,以使这些部分保持基本上直线。 环形构件,加强构件和内壁中的每一个可以具有任何几何形状的横截面或轮廓,以在优选平面中提供期望的弯曲偏压。 在本发明的另一方面,环形构件还包括放置在第二内腔内的第二内腔和第二加强构件,以提供期望的弯曲偏压。
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公开(公告)号:US20050192605A1
公开(公告)日:2005-09-01
申请号:US10664698
申请日:2004-02-06
申请人: Charles Hart , Donald Gadberry , Eduardo Chi-Sing , Mark Ashby , Luis Urquidi , Robert Jones
发明人: Charles Hart , Donald Gadberry , Eduardo Chi-Sing , Mark Ashby , Luis Urquidi , Robert Jones
IPC分类号: A61B17/00 , A61B17/02 , A61B17/122 , A61B17/28 , A61B17/08
CPC分类号: A61B17/02 , A61B17/122 , A61B17/1227 , A61B2017/00858 , A61B2017/00862 , A61B2017/0243 , A61B2017/2825
摘要: A surgical instrument (10) is adapted to contact tissue of a patient, and to provide traction with the tissue in order to inhibit migration of the instrument relative to the tissue. The instrument may include a pair of opposing jaws (16, 18) with at least one of the jaws (16, 18) comprising a substrate having a particular surface facing the tissue, and a plurality of discrete elements (26, 28) disposed on the particular surface for increasing the traction of the instrument relative to the tissue. These discrete elements (26, 28) may include a multiplicity of granules, bristles, or projections, and may be formed of materials having various properties such as hydrophilic characteristics. The discrete elements in the form of bristles can be oriented too so that the column strength of each bristle provides increased traction in a predetermined direction.
摘要翻译: 手术器械(10)适于接触患者的组织,并提供对组织的牵引,以便抑制器械相对于组织的移动。 仪器可以包括一对相对的夹爪(16,18),其中至少一个钳口(16,18)包括具有面向组织的特定表面的衬底,以及多个分立元件(26,28),其设置在 用于增加器械相对于组织的牵引力的特定表面。 这些离散元件(26,28)可以包括多个颗粒,刷毛或凸起,并且可以由具有各种性质如亲水特性的材料形成。 刷毛形式的离散元件也可以被定向,使得每个刷毛的柱强度在预定方向上提供增加的牵引力。
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公开(公告)号:US20050031694A1
公开(公告)日:2005-02-10
申请号:US10910938
申请日:2004-08-03
申请人: Debra Gilbertson , Charles Hart
发明人: Debra Gilbertson , Charles Hart
CPC分类号: C04B38/06 , A61K38/177 , A61K38/18 , A61K38/1866 , A61K38/22 , C04B2111/00224 , C04B2111/00612 , C07K14/52 , C07K2319/00 , C12N2799/022 , C04B20/008 , C04B35/2641 , C04B35/50 , C04B35/64 , C04B38/0054 , C04B38/007 , C04B41/4578 , A61K2300/00
摘要: Methods for promoting growth of bone, ligament, or cartilage in a mammal are disclosed. The methods comprise administering to said mammal a composition comprising a pharmacologically effective amount of zvegf4 in combination with a pharmaceutically acceptable delivery vehicle. Also disclosed are methods for promoting proliferation or differentiation of osteoblasts, osteoclasts, chondrocytes, or bone marrow stem cells comprising culturing the cells in an effective amount of zvegf4.
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公开(公告)号:US20050020884A1
公开(公告)日:2005-01-27
申请号:US10927551
申请日:2004-08-25
申请人: Charles Hart , Edward Pingleton
发明人: Charles Hart , Edward Pingleton
CPC分类号: A61B17/0293 , A61B17/3423 , A61B17/3498 , A61B2017/00265
摘要: The invention is directed to a hand access system that provides hand access to a surgical area while maintaining pneumoperitoneum during laparoscopic surgery. The hand access system comprises a sheath retractor adapted to dilate a wound stretchable to a desired diameter, the sheath retractor includes a first ring being adapted for disposition interiorly of the wound, a second ring being adapted for disposition exteriorly of the wound, and a sheath being disposed in a generally cylindrical form between the first ring and the second ring and operable to exert a radial retraction force on the wound. The hand access system further comprises a detachable hand seal adapted to be removable from the second ring of the sheath retractor. The sheath retractor may be formed of an elastomeric material, and the hand seal may be formed of a gel material and includes a slit providing an instrument seal in the presence of an instrument or hand and a zero seal in the absence of the instrument or hand. In another aspect, there is disclosed a surgical access device adapted for disposition relative to an incision in a patient comprising a valve including a plurality of overlapping sheets defining an access channel, and a ring having an inner diameter for holding the valve by fixing each of the overlapping sheets along a portion of the perimeter, the access channel extends into communication with the incision in the patient. Each of the overlapping sheets includes a portion of the perimeter that is not fixed to the inner diameter of the ring, which provide open edges defining the access channel. The open edges slightly overlap at the center of the ring. The open edges may have different shapes including at least one of a straight edge, concave, convex and a cross-configuration. The hand access device may further comprise a septum seal formed at the proximal and distal ends of the ring.
摘要翻译: 本发明涉及一种手动进入系统,其在腹腔镜手术期间提供手术进入手术区域同时保持气腹。 手动进入系统包括一个适合于将可拉伸到所需直径的伤口扩张的护套牵开器,所述护套牵开器包括适于在伤口内部配置的第一环,适于在伤口外部配置的第二环, 在第一环和第二环之间以大致圆柱形的形式设置并可操作以在伤口上施加径向缩回力。 手动进入系统还包括适于从皮带牵开器的第二环移除的可拆卸手动密封件。 护套牵开器可以由弹性体材料形成,并且手动密封件可以由凝胶材料形成,并且包括在没有仪器或手的情况下在仪器或手的存在下提供仪器密封的狭缝和零密封 。 另一方面,公开了一种外科进入装置,其适于相对于患者的切口进行配置,该装置包括阀,所述阀包括限定出入通道的多个重叠片,以及具有用于通过固定每个 沿着周边的一部分重叠的片材,进入通道延伸成与患者的切口连通。 每个重叠片材包括未固定到环的内径的周边的一部分,其提供限定接入通道的开口边缘。 开口边缘在环的中心稍微重叠。 开口边缘可以具有不同的形状,包括直边,凹形,凸形和交叉构型中的至少一个。 手动进入装置还可以包括形成在环的近端和远端的隔膜密封件。
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公开(公告)号:US20090077584A1
公开(公告)日:2009-03-19
申请号:US11901319
申请日:2007-09-17
IPC分类号: H04N5/445
CPC分类号: H04N5/44543 , H04N7/173 , H04N21/252 , H04N21/44222 , H04N21/4532 , H04N21/6582 , H04N21/84
摘要: Methods, systems, and products are disclosed for sharing presence information. Presence notifications are received from users, and the presence notifications describe content items currently being received by the users. A popularity of one or more of the content items being received by the users is determined. An electronic programming guide is provided that includes information regarding the one or more of the content items and the determined popularity associated with the one or more of the content items.
摘要翻译: 公开了用于共享存在信息的方法,系统和产品。 来自用户的存在通知,存在通知描述用户当前正在接收的内容。 确定由用户接收的一个或多个内容项的流行度。 提供电子节目指南,其包括关于一个或多个内容项目的信息以及与一个或多个内容项目相关联的所确定的流行度。
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公开(公告)号:US20070244497A1
公开(公告)日:2007-10-18
申请号:US11735798
申请日:2007-04-16
申请人: Russell Ahlberg , Charles Hart , Steven Kessler
发明人: Russell Ahlberg , Charles Hart , Steven Kessler
IPC分类号: A61B17/3201
CPC分类号: A61B17/3201 , A61B17/320016 , B24B3/52 , B26B13/06 , B26B13/08
摘要: A laparoscopic scissor with a shaft for use through an access port, such as a trocar cannula, with one or more parabolic, cubic, quadratic or higher order cutting blades extending from the shaft is provided.
摘要翻译: 提供了一种具有轴的腹腔镜剪刀,其通过诸如套管针套管的进入口使用,具有从轴延伸的一个或多个抛物线,立方,二次或更高次级的切割刀片。
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公开(公告)号:US20070135781A1
公开(公告)日:2007-06-14
申请号:US11549701
申请日:2006-10-16
申请人: Charles Hart
发明人: Charles Hart
IPC分类号: A61M1/00
CPC分类号: A61B17/00234 , A61B2017/00287
摘要: A tissue isolation and removal device has a containment pouch that is opened and supported by the device. The pouch has two open/close portions both able to be closed and reopened. One portion positioned away from tissue being inserted in the pouch and covering the other portion to enclose or isolate any tissue captured in the other portion.
摘要翻译: 组织隔离和去除装置具有由装置打开和支撑的容纳袋。 该袋具有两个打开/关闭部分,能够关闭并重新打开。 位于远离组织的一部分被插入袋中并覆盖另一部分以包围或隔离在另一部分中捕获的任何组织。
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公开(公告)号:US20070060507A1
公开(公告)日:2007-03-15
申请号:US11552378
申请日:2006-10-24
IPC分类号: A61K38/18 , C07K14/475
CPC分类号: C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要: Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译: 公开了多肽生长因子,其制备方法,编码它们的多核苷酸,针对它们的抗体以及使用它们的方法。 多肽包含与SEQ ID NO:2的残基46-163或SEQ ID NO:2的残基235-345至少90%相同的氨基酸区段。 还公开了多肽的多聚体。 多肽,多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节,作为细胞培养基的组分和诊断剂。
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公开(公告)号:US20070009863A1
公开(公告)日:2007-01-11
申请号:US10964955
申请日:2004-10-14
申请人: Alan Hart , Charles Hart
发明人: Alan Hart , Charles Hart
IPC分类号: G09B29/00
摘要: A trail map directory for off-highway vehicles is disclosed. The directory includes a binder having a plurality of individual map pages laminated for dry ease writing and for ease of cleaning. A mechanism is provided for releasably attaching each map page to the binder. A key map is positioned towards the front of the binder, and the key map is subdivided into individual regional map display portions corresponding to the individual map pages. Each map page is preferably a substantially flat, relatively stiff laminated panel. The panel has first and second faces located on opposite surfaces thereof, and first and second side edges which define the width dimension of the panel. Each panel first face includes an enlarged map display portion indexed relative to the key map and is in the form of an enhanced topographical map overlaid with off-road trails present within the map boundary. The trails are color-coded to indicate relative difficulty of use. The first face further includes trail symbols relative to the indicated off-road trails. Each second face includes an index to trail symbols appearing on the first face. The second face may also include GPS coordinates pertinent to the geographical points on the topographical map as well as driving directions to the off-road trails. Finally, an apparatus is disposed along each panel first side edge for releasably attaching the panel to the binder for removal for individual use.
摘要翻译: 公开了一种用于非公路车辆的轨迹图目录。 该目录包括具有多个单独的地图页面的粘合剂,用于干燥书写和易于清洁。 提供了一种用于将每个地图页面可释放地附接到装订器的机构。 关键地图朝向装订器的前部定位,并且将关键图细分成与各个地图页对应的各个区域地图显示部分。 每个地图页面优选地是基本平坦的,相对较硬的层压板。 面板具有位于其相对表面上的第一和第二面,以及限定面板的宽度尺寸的第一和第二侧边缘。 每个面板第一面包括相对于键映射索引的放大地图显示部分,并且是以与地图边界内存在的越野轨迹重叠的增强的地形图的形式。 路线是颜色编码的,表示使用相对困难。 第一面还包括相对于指示的越野路线的轨迹符号。 每个第二面包括一个索引,用于跟踪出现在第一面上的符号。 第二面还可以包括与地形图上的地理点相关的GPS坐标以及到越野小径的驾驶方向。 最后,沿着每个面板第一侧边缘设置一个装置,用于可释放地将面板连接到粘合剂上用于单独使用。
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公开(公告)号:US20050159358A1
公开(公告)日:2005-07-21
申请号:US11021088
申请日:2004-12-22
申请人: Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
发明人: Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
IPC分类号: A61K38/00 , A61K38/18 , C07K14/475 , C07K14/52 , C07H21/04
CPC分类号: C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要: Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译: 公开了多肽生长因子,其制备方法,编码它们的多核苷酸,针对它们的抗体以及使用它们的方法。 所述多肽包含与SEQ ID NO:2的残基46-163或SEQ ID NO:2的残基235-345至少90%相同的氨基酸区段。 还公开了多肽的多聚体。 多肽,多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节,作为细胞培养基的组分和诊断剂。
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