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公开(公告)号：US09289522B2
公开(公告)日：2016-03-22
申请号：US14381551
申请日：2013-02-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Bradley H. Buchanan
Abstract: A system for sterilizing a fluid includes a fluid source and a sterilization container bounding a fluid flow path that is in fluid communication with the fluid source. The sterilization container is comprised of one or more polymeric walls. An electron beam generator is configured to direct an electron beam through at least a portion of the fluid flow path of the sterilization container, the electron beam being sufficient to sterilize a fluid within the fluid flow path.
Abstract translation: 用于对流体灭菌的系统包括流体源和限定与流体源流体连通的流体流动路径的灭菌容器。 灭菌容器由一个或多个聚合物壁组成。 电子束发生器被配置为引导电子束通过灭菌容器的流体流动路径的至少一部分，电子束足以对流体流动路径内的流体进行消毒。
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公开(公告)号：US20150190764A1
公开(公告)日：2015-07-09
申请号：US14663068
申请日：2015-03-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Jeremy K. Larsen
CPC classification number: B01F15/0085 , B01F3/04269 , B01F3/04439 , B01F3/04829 , B01F5/04 , B01F7/00341 , B01F7/22 , B01F11/0082 , B01F13/0255 , B01F2003/04276 , B01F2003/04297 , B01F2003/04312 , B01F2003/04326 , B01F2003/04361 , B01F2003/04382 , B01F2003/04397 , B01F2215/0073 , C12M23/14 , C12M23/20 , C12M23/26 , C12M27/04 , C12M29/06 , C12M37/00
Abstract: A container system includes a bag having of one or more sheets of flexible polymeric material, the bag having an interior surface at least partially bounding a chamber, the chamber being adapted to hold a fluid. A flexible sparging sheet is secured to the interior surface of the bag so that a compartment is formed between the interior surface of the bag and the sparging sheet, at least a portion of the sparging sheet allowing gas to pass therethrough. A tubular port or tube is secured with the bag or the sparging sheet so that a passage bounded by the tubular port or tube communicates with the compartment.
Abstract translation: 容器系统包括具有一层或多层柔性聚合物材料的袋，该袋具有至少部分地限定室的内表面，该室适于容纳流体。 将柔性喷射片固定到袋的内表面，使得在袋的内表面和喷射片之间形成隔室，至少一部分鼓泡片允许气体通过。 用袋或喷射片固定管状端口或管，使得由管状端口或管限定的通道与隔室连通。
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公开(公告)号：US20150138913A1
公开(公告)日：2015-05-21
申请号：US14405126
申请日：2013-02-26
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Nephi D. Jones , Brandon M. Knudsen , Whitt F. Woods
CPC classification number: B01F15/0085 , B01F7/001 , B01F7/00725 , B01F7/1615 , B01F7/1695 , B01F7/22 , B01F11/0008 , B01F11/0017 , B01F15/00733 , B01F15/0074 , B01F15/00772 , B01F15/0203 , B01F15/0295 , B01F2015/0221 , C12M23/14 , C12M23/48 , C12M23/52 , C12M27/00 , C12M27/02 , C12M27/16 , C12M29/06
Abstract: A fluid mixing system that can be used as a bioreactor or fermentor can include a stand and a support housing pivotably mounted to the stand. The support housing bounds a chamber into which a container assembly is removably disposed. The container assembly includes a flexible bag bounding a compartment adapted to hold a fluid and a mixing element disposed within the compartment. The support housing can be tilted relative to the stand for ease in insertion of the container assembly. The support housing can also be repeatedly rocked relative to the stand form mixing fluid within the container assembly.
Abstract translation: 可用作生物反应器或发酵罐的流体混合系统可以包括支架和可枢转地安装在支架上的支撑壳体。 支撑壳体限定容器组件可移除地设置在其中的室。 容器组件包括柔性袋，其包围适于保持流体的室和设置在室内的混合元件。 支撑壳体可以相对于支架倾斜，以便于容器组件的插入。 支撑壳体也可以相对于在容器组件内混合流体的支架形式重复摇动。
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公开(公告)号：US12138605B2
公开(公告)日：2024-11-12
申请号：US17165564
申请日：2021-02-02
Applicant: Life Technologies Corporation
Inventor： Nephi D. Jones , Jason D. Brown
IPC: B01F7/00 , B01F7/22 , B01F15/00 , B01F27/07 , B01F27/072 , B01F27/113 , B01F27/191 , B01F27/91 , B01F35/513 , C12M1/06 , B01F101/44
Abstract: A mixing system for mixing a liquid includes a first impeller segment having a first mount and a first mixing blade secured to the first mount and a second impeller segment having a second mount and a first mixing blade secured to the second mount, the second impeller segment being separate and discrete from the first impeller segment. One or more drive members are secured to the first impeller segment and the second impeller segment for concurrently rotating the first impeller segment and the second impeller segment about a rotational axis. The first impeller segment and the second impeller segment are secured to the one or more drive members so that a plane extending normal to the axis of rotation intersects with the first mixing blade of the first impeller segment and the first mixing blade of the second impeller segment.
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公开(公告)号：US11999930B2
公开(公告)日：2024-06-04
申请号：US18336338
申请日：2023-06-16
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones
IPC: C12M1/06 , B01F27/07 , B01F27/113 , B01F27/2121 , B01F27/213 , B01F27/231 , B01F27/61 , B01F33/00 , B01F35/22 , B01F35/513 , C12M1/00 , C12M1/34 , C12M3/00 , B01F35/71
CPC classification number: C12M23/14 , B01F27/071 , B01F27/113 , B01F27/2121 , B01F27/213 , B01F27/2312 , B01F27/61 , B01F33/86 , B01F35/2209 , B01F35/513 , C12M23/26 , C12M23/48 , C12M23/52 , C12M27/02 , C12M27/06 , C12M41/00 , B01F35/715
Abstract: A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.
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Patent Agency Ranking
公开(公告)号：US11725171B2
公开(公告)日：2023-08-15
申请号：US16502245
申请日：2019-07-03
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones
IPC: C12M1/00 , C12M3/00 , C12M1/06 , C12M1/34 , B01F27/61 , B01F27/07 , B01F27/113 , B01F27/213 , B01F27/2121 , B01F27/231 , B01F33/00 , B01F35/513 , B01F35/22 , B01F35/71
CPC classification number: C12M23/14 , B01F27/071 , B01F27/113 , B01F27/213 , B01F27/2121 , B01F27/2312 , B01F27/61 , B01F33/86 , B01F35/2209 , B01F35/513 , C12M23/26 , C12M23/48 , C12M23/52 , C12M27/02 , C12M27/06 , C12M41/00 , B01F35/715
Abstract: A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.
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公开(公告)号：US11591556B2
公开(公告)日：2023-02-28
申请号：US16863702
申请日：2020-04-30
Inventor： Kurt T. Kunas , Robert V. Oakley , Fauad F. Hasan , Michael E. Goodwin , Jeremy K. Larsen , Nephi D. Jones
IPC: C12M1/00 , B01F27/07 , B01F27/88 , B01F27/91 , B01F33/00 , B01F35/51 , B01F35/513 , C12M1/06 , C12M1/12 , B01F101/44
Abstract: A reactor system includes a support housing having an interior surface bounding a chamber, the chamber having a vertically extending central longitudinal axis. A flexible bag is disposed within the chamber of the support housing and has an interior surface bounding a compartment. A mixing element is disposed within the compartment of the flexible bag. A drive element, such as a drive shaft, is secured the mixing element, wherein the mixing element is laterally offset from and/or is angled relative to the vertically extending central longitudinal axis of the support housing.
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公开(公告)号：US20220054954A1
公开(公告)日：2022-02-24
申请号：US17521445
申请日：2021-11-08
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Scott P. Collins , Christopher D. Brau , Nephi D. Jones
Abstract: A sample purification system includes a mixing zone; a settling zone in fluid communication with the mixing zone; a mixer element disposed in the mixing zone, the mixer element being configured to mix immiscible liquids to form a mixture; and a first acoustic wave settler configured to emit an acoustic wave into the mixture.
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公开(公告)号：US11162062B2
公开(公告)日：2021-11-02
申请号：US16715087
申请日：2019-12-16
Applicant: Life Technologies Corporation
Inventor： Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
IPC: C12N1/00 , C12M1/00 , B01F13/02 , B01F3/04 , C12M1/02 , C12M1/34 , B01F7/22 , B01F15/00 , C12M1/06 , B01F11/00
Abstract: A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween. A tube has a first end and an opposing second end, the first end of the tube being disposed within the compartment of the container. A nozzle is disposed within the compartment of the container and has at least one outlet, the nozzle being coupled with the tube so that a gas can be passed through the tube and out the at least one outlet of the nozzle. The nozzle is sufficiently buoyant so that when a fluid is disposed within the compartment of the container, the nozzle floats on the fluid.
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公开(公告)号：US20210237009A1
公开(公告)日：2021-08-05
申请号：US17165564
申请日：2021-02-02
Applicant: Life Technologies Corporation
Inventor： Nephi D. Jones , Jason D. Brown
Abstract: A mixing system for mixing a liquid includes a first impeller segment having a first mount and a first mixing blade secured to the first mount and a second impeller segment having a second mount and a first mixing blade secured to the second mount, the second impeller segment being separate and discrete from the first impeller segment. One or more drive members are secured to the first impeller segment and the second impeller segment for concurrently rotating the first impeller segment and the second impeller segment about a rotational axis. The first impeller segment and the second impeller segment are secured to the one or more drive members so that a plane extending normal to the axis of rotation intersects with the first mixing blade of the first impeller segment and the first mixing blade of the second impeller segment.
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