公开(公告)号：US11229796B2

公开(公告)日：2022-01-25

申请号：US16220093

申请日：2018-12-14

Applicant: Medtronic, Inc.

Inventor： Yanzhu Zhao ,  Yong K. Cho ,  Michael D. Eggen ,  Wei Gan ,  Kathryn Hilpisch ,  Srikara V. Peelukhana ,  Darrell J. Swenson ,  Joshua J. Blauer

IPC: A61N1/372 ,  A61N1/39 ,  A61N1/36 ,  A61N1/362

Abstract: A device and method are described for transmitting tissue conductance communication (TCC) signals. A device may be is configured to establish a transmission window by transmitting a TCC test signal at multiple time points over a transmission test period to a receiving device and detect at least one response to the transmitted TCC test signals performed by the receiving device. The IMD is configured to establish the transmission window based on the at least one detected response so that the transmission window is correlated to a time of relative increased transimpedance between a transmitting electrode vector and receiving electrode vector during the transmission test period.

公开(公告)号：USRE48197E1

公开(公告)日：2020-09-08

申请号：US16045277

申请日：2018-07-25

Applicant: Medtronic, Inc.

Inventor： Yong K. Cho ,  Aleksandre T. Sambelashvili ,  Todd J. Sheldon

IPC: A61N1/00 ,  A61N1/365 ,  A61N1/372 ,  A61N1/375 ,  A61N1/06

Abstract: A leadless pacing device (LPD) includes a motion sensor configured to generate a motion signal as a function of heart movement. The LPD is configured to analyze the motion signal within an atrial contraction detection window that begins an atrial contraction detection delay period after activation of the ventricle, and detect a contraction of an atrium of the heart based on the analysis of the motion signal within the atrial contraction detection window. If the LPD does not detect a ventricular depolarization subsequent to the atrial contraction, e.g., with an atrio-ventricular (AV) interval beginning when the atrial contraction was detected, the LPD delivers a ventricular pacing pulse.

公开(公告)号：US09597511B2

公开(公告)日：2017-03-21

申请号：US13663920

申请日：2012-10-30

Applicant: Medtronic, Inc.

Inventor： Yong K. Cho ,  Douglas A. Hettrick ,  Todd M. Zielinski

IPC: A61N1/365 ,  A61N1/368

CPC classification number: A61N1/36521 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3686

Abstract: An implantable medical device and associated method to determine an optimal control parameter setting for controlling a cardiac therapy that includes a therapy delivery module to deliver cardiac pacing signals at a plurality of pacing rates, and an admittance measurement module to determine admittance signals associated with each of the plurality of pacing rates. A control unit determines metrics of hemodynamic performance corresponding to each of the plurality of pacing rates in response to the determined admittance signals, identifies pacing rates of the plurality of pacing rates as rejected rates in response to the determined metrics of hemodynamic performance, and determines a pacing rate of the plurality of pacing rates as an optimal rate for delivering the cardiac therapy in response to the identified pacing rates.

公开(公告)号：US20160220825A1

公开(公告)日：2016-08-04

申请号：US15005533

申请日：2016-01-25

Applicant: Medtronic, Inc.

Inventor： Saul E. Greenhut ,  Robert T. Taepke ,  David R. Bloem ,  Yong K. Cho ,  Donna M. Salmi

IPC: A61N1/365 ,  A61N1/39 ,  A61M5/172 ,  A61B5/0215 ,  A61B5/00

CPC classification number: A61N1/36564 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/0422 ,  A61B5/6847 ,  A61B5/686 ,  A61B5/6869 ,  A61B5/6876 ,  A61B5/7239 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2205/054 ,  A61M2210/125 ,  A61N1/37247 ,  A61N1/3962 ,  A61N1/3987

Abstract: Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point.

Abstract translation: 描述了基于肺动脉压力测量心脏周期长度和压力指标的各种技术。 所描述的一个示例性方法包括识别心血管压力信号的导数信号内的点，而不参考心脏的电活动，从导数信号中的识别点开始时间窗口，识别时间窗内的心血管信号内的点 并且基于所识别的点来确定收缩压或舒张压中的至少一个。

公开(公告)号：US08868185B2

公开(公告)日：2014-10-21

申请号：US13686359

申请日：2012-11-27

Applicant: Medtronic, Inc.

Inventor： Todd M. Zielinski ,  Douglas A. Hettrick ,  Yong K. Cho ,  Eduardo N. Warman ,  Paul A. Sobotka

IPC: A61N1/368 ,  A61N1/365 ,  A61M27/00

CPC classification number: A61N1/36507 ,  A61B5/0537 ,  A61B5/085 ,  A61M27/00 ,  A61N1/3627 ,  A61N1/36521

Abstract: A medical device and associated method for delivery of a cardiac therapy that includes determining a first impedance signal along a thoracic electrode vector extending within a portion of a thoracic cavity, determining a second impedance signal along an extra-thoracic electrode vector extending outside the thoracic cavity, comparing first amplitude measurements corresponding to the first impedance signals and second amplitude measurements corresponding to the second impedance signals, comparing first slope measurements corresponding to the first impedance signals and second slope measurements corresponding to the second impedance signals, and determining delivery of the cardiac therapy in response to the comparing.

Abstract translation: 一种用于递送心脏疗法的医疗装置和相关联的方法，其包括沿着在胸腔的一部分内延伸的胸部电极矢量确定第一阻抗信号，沿着延伸到胸腔外部的胸外电极矢量确定第二阻抗信号 比较对应于第一阻抗信号的第一振幅测量值和对应于第二阻抗信号的第二振幅测量值，比较对应于第一阻抗信号的第一斜率测量值和对应于第二阻抗信号的第二斜率测量值，以及确定心脏治疗 响应比较。

公开(公告)号：US20130197386A1

公开(公告)日：2013-08-01

申请号：US13744461

申请日：2013-01-18

Applicant: Medtronic, Inc.

Inventor： Yong K. Cho ,  Mark K. Erickson ,  Douglas A. Hettrick

IPC: A61B5/085 ,  A61B5/08

CPC classification number: A61B5/085 ,  A61B5/0031 ,  A61B5/0422 ,  A61B5/0538 ,  A61B5/08 ,  A61B5/0809 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/113 ,  A61B5/4818 ,  A61B5/686 ,  A61B7/00

Abstract: A system and method for monitoring respiratory function that includes an acoustic sensing device sensing an acoustic waveform ocurring during one of an inspiration phase associated with at least one breath of a patient and an expiration phase associated with at least one breath of a patient, and a processor configured to determine changes in high frequency acoustic amplitude associated with the sensed acoustic waveform and, in response to the determined changes in high frequency acoustic amplitude, determine an indication of respiratory function.

Abstract translation: 一种用于监测呼吸功能的系统和方法，其包括声学感测装置，其感测在与患者的至少一个呼吸相关联的吸气阶段期间的声波形和与患者的至少一个呼吸相关联的呼气阶段， 处理器被配置为确定与感测的声波形相关联的高频声振幅的变化，并且响应于所确定的高频声振幅的变化，确定呼吸功能的指示。

公开(公告)号：US20130110188A1

公开(公告)日：2013-05-02

申请号：US13663920

申请日：2012-10-30

Applicant: Medtronic , Inc.

Inventor： Yong K. Cho ,  Douglas A. Hettrick ,  Todd M. Zielinski

IPC: A61N1/365

CPC classification number: A61N1/36521 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3686

Abstract: An implantable medical device and associated method to determine an optimal control parameter setting for controlling a cardiac therapy that includes a therapy delivery module to deliver cardiac pacing signals at a plurality of pacing rates, and an admittance measurement module to determine admittance signals associated with each of the plurality of pacing rates. A control unit determines metrics of hemodynamic performance corresponding to each of the plurality of pacing rates in response to the determined admittance signals, identifies pacing rates of the plurality of pacing rates as rejected rates in response to the determined metrics of hemodynamic performance, and determines a pacing rate of the plurality of pacing rates as an optimal rate for delivering the cardiac therapy in response to the identified pacing rates.

Abstract translation: 一种可植入医疗装置和相关联的方法，用于确定用于控制心脏治疗的最佳控制参数设置，所述心脏治疗包括治疗递送模块，其以多个起搏速率递送心脏起搏信号;以及导纳测量模块，用于确定与每个起搏信号相关联的导纳信号 多个起搏率。 响应于所确定的导纳信号，控制单元确定对应于多个起搏速率中的每一个的血流动力学性能的指标，根据所确定的血流动力学性能的度量，将多个起搏速率的起搏速率识别为拒绝率，并且确定 多个起搏速率的起搏速率作为响应于所识别的起搏速率递送心脏治疗的最佳速率。