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公开(公告)号：US11116456B2
公开(公告)日：2021-09-14
申请号：US16454679
申请日：2019-06-27
Applicant: Medtronic, Inc.
Inventor： Douglas A. Hettrick , John E. Burnes , Tommy D. Bennett , Shantanu Sarkar , Eduardo N. Warman , Todd M. Zielinski
IPC: A61B5/00 , A61B5/021 , A61B5/0295 , A61B5/053 , A61B5/0538 , A61B5/07 , A61N1/365 , A61N1/372 , A61N1/375
Abstract: In some examples, determining a heart failure status of a patient using a medical device comprising a plurality of electrodes includes determining an estimated arterial pressure waveform of the patient based on an arterial impedance signal received from at least two of the plurality of electrodes. The estimated arterial pressure waveform may comprise a plurality of arterial pressure cycles. Each of the plurality of arterial pressure cycles may correspond to a different cardiac cycle of a plurality of cardiac cycles of the patient. At least one value of an intrinsic frequency of the corresponding arterial pressure cycle may be determined for at least some of the plurality of cardiac cycles and the heart failure status of the patient may be determined based on the at least one value of the intrinsic frequency.
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2.发明申请USE OF THORACIC AND EXTRA-THORACIC IMPEDANCE FOR DIAGNOSTIC MONITORING 审中-公开用于诊断监测的THORACIC和超声阻抗的使用公开(公告)号：US20140148656A1
公开(公告)日：2014-05-29
申请号：US13686308
申请日：2012-11-27
Applicant: MEDTRONIC, INC.
Inventor： Todd M. Zielinski , Douglas A. Hettrick , Yong K. Cho , Eduardo N. Warman , Paul A. Sobotka
CPC classification number: A61B5/0537 , A61B5/0538 , A61B5/1116 , A61B5/4857 , A61M5/1723 , A61N1/36114 , A61N1/3627
Abstract: A medical device and associated method for monitoring a fluid status of a patient that includes determining a first impedance signal along an electrode vector comprising a portion of a thoracic cavity, determining a second impedance signal along an extra-thoracic electrode vector, and determining a fluid status measurement in response to the determined first impedance signal and the determined second impedance signal
Abstract translation: 一种用于监测患者的流体状态的医疗装置和相关联的方法，其包括沿着包括胸腔的一部分的电极矢量确定第一阻抗信号，沿着胸外电极向量确定第二阻抗信号，以及确定流体 响应于所确定的第一阻抗信号和所确定的第二阻抗信号的状态测量
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公开(公告)号：US10182729B2
公开(公告)日：2019-01-22
申请号：US15253229
申请日：2016-08-31
Applicant: Medtronic, Inc.
Inventor： Todd M. Zielinski , David A. Anderson , Tom D. Bennett , James K. Carney , Can Cinbis , Yong K. Cho , Jonathan L. Kuhn , Brian B. Lee , Richard J. O'Brien , Eduardo N. Warman , Vinod Sharma
IPC: A61B5/04 , A61B5/021 , A61B5/00 , A61B5/0205 , A61B5/026 , A61B5/0402 , A61B5/08
Abstract: The exemplary systems and methods may monitor one or more signals to be used to assess the hemodynamic status of a patient. The one or more signals may be used to calculate, or determine, a plurality of pulse transit times. The plurality of pulse transit times may be used to determine hemodynamic status values that may be indicative of a patient's aggregate hemodynamic status.
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4.发明授权公开(公告)号：US09707399B2
公开(公告)日：2017-07-18
申请号：US15204464
申请日：2016-07-07
Applicant: Medtronic, Inc.
Inventor： Todd M. Zielinski , Yong Kyun Cho , Douglas Hettrick , Xusheng Zhang
CPC classification number: A61N1/36585 , A61B5/0535 , A61B5/0538 , A61N1/36521 , A61N1/3682 , A61N1/3684 , A61N1/3686
Abstract: Methods and/or devices used in delivering cardiac resynchronization therapy based on a plurality of device parameters (e.g., A-V delay, V-V delay, etc.) are optimized by setting a device parameter based on selection data. The selection data may be acquired by acquiring temporal fiducial points (e.g., heart sounds) associated with at least a part of a systolic portion of at least one cardiac cycle and/or temporal fiducial points associated with at least a part of a diastolic portion of the at least one cardiac cycle for each of a plurality of electrode vector configurations, and extracting measurements from the intracardiac impedance signal acquired for each of a plurality of electrode vector configurations based on the temporal fiducial points. The acquired selection data may be scored and used to optimize the device parameter.
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公开(公告)号：US09682240B2
公开(公告)日：2017-06-20
申请号：US15219595
申请日：2016-07-26
Applicant: Medtronic, Inc.
Inventor： Douglas A. Hettrick , Todd M. Zielinski , Eduardo Warman , Shantanu Sarkar
CPC classification number: A61N1/36521 , A61B5/0452 , A61B5/0535 , A61B5/7239 , A61N1/3627 , A61N1/3682 , A61N1/3684 , A61N1/3987
Abstract: Methods and/or devices are disclosed herein for monitoring cardiac impedance signal and delivering therapy to a patient's heart based upon the monitored cardiac impedance.
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Patent Agency Ranking
6.发明申请CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION BASED ON INTRACARDIAC IMPEDANCE AND HEART SOUNDS 有权基于内皮抑素和心脏疾病的心脏康复治疗优化公开(公告)号：US20150202443A1
公开(公告)日：2015-07-23
申请号：US14158533
申请日：2014-01-17
Applicant: Medtronic, Inc.
Inventor： Todd M. Zielinski , Yong Kyun Cho , Douglas Hettrick , Xusheng Zhang
CPC classification number: A61N1/36585 , A61B5/0535 , A61B5/0538 , A61N1/36521 , A61N1/3682 , A61N1/3684 , A61N1/3686
Abstract: Methods and/or devices used in delivering cardiac resynchronization therapy based on a plurality of device parameters (e.g., A-V delay, V-V delay, etc.) are optimized by setting a device parameter based on selection data. The selection data may be acquired by acquiring temporal fiducial points (e.g., heart sounds) associated with at least a part of a systolic portion of at least one cardiac cycle and/or temporal fiducial points associated with at least a part of a diastolic portion of the at least one cardiac cycle for each of a plurality of electrode vector configurations, and extracting measurements from the intracardiac impedance signal acquired for each of a plurality of electrode vector configurations based on the temporal fiducial points. The acquired selection data may be scored and used to optimize the device parameter.
Abstract translation: 通过基于选择数据设置设备参数来优化基于多个设备参数（例如，A-V延迟，V-V延迟等）递送心脏再同步治疗的方法和/或设备。 选择数据可以通过获取与至少一个心动周期的收缩期部分的至少一部分相关联的时间基准点（例如，心音）和/或与至少一个心动周期的舒张部分的至少一部分相关联的时间基准点来获取 所述至少一个心脏周期用于多个电极向量配置中的每一个，并且基于所述时间基准点从针对多个电极向量配置中的每一个获取的心脏内阻抗信号提取测量值。 可以对所获取的选择数据进行评分并用于优化设备参数。
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公开(公告)号：US20230380705A1
公开(公告)日：2023-11-30
申请号：US18141953
申请日：2023-05-01
Applicant: Medtronic, Inc.
Inventor： Richard J. O'Brien , Todd M. Zielinski , Nathan A. Torgerson , Lilian Kornet , Richard N. Cornelussen , Shantanu Sarkar , Veronica Ramos , Douglas A. Hettrick , Yong K. Cho
IPC: A61B5/021 , A61B5/0205 , A61B5/024 , A61B5/00
CPC classification number: A61B5/02125 , A61B5/0205 , A61B5/02438 , A61B5/4839
Abstract: A system may measure, by one or more sensors, a biometric parameter associated with a subject. The system may determine values of a control parameter based on measuring the biometric parameter. The control parameter may include blood pressure of the subject. The system may perform a control measure based on a comparison of the values of the control parameters to a threshold. Performing the control measure may include delivering therapy treatment to the subject or outputting a notification indicating an action associated with treating a medical condition. Measuring the biometric parameter, determining the values of the control parameter, and performing the control measure may be in response to one or more trigger criteria.
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公开(公告)号：US11298547B2
公开(公告)日：2022-04-12
申请号：US16521963
申请日：2019-07-25
Applicant: Medtronic, Inc.
Inventor： Zhendong Song , Todd M. Zielinski , Brian B. Lee
IPC: A61B5/352 , A61N1/365 , A61B5/11 , A61B5/00 , A61B5/283 , A61B5/0537 , A61B5/0538
Abstract: A medical device is configured to generate fluid status signal data of a patient by determining impedance metrics from an impedance signal, determining cardiac electrical signal amplitudes from a cardiac electrical signal and determining a calibration relationship between the impedance metrics and cardiac electrical signal amplitudes. The medical device generates a fluid status signal data by adjusting cardiac electrical signal amplitudes according to the determined calibration relationship. The fluid status signal data may be displayed or monitored for detecting a change in the patient's fluid status.
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公开(公告)号：US20180055386A1
公开(公告)日：2018-03-01
申请号：US15253229
申请日：2016-08-31
Applicant: Medtronic, Inc.
Inventor： Todd M. Zielinski , David A. Anderson , Tom D. Bennett , James K. Carney , Can Cinbis , Yong K. Cho , Jonathan L. Kuhn , Brian B. Lee , Richard J. O'Brien , Eduardo N. Warman , Vinod Sharma
IPC: A61B5/021 , A61B5/00 , A61B5/026 , A61B5/0402 , A61B5/0205 , A61B5/08
CPC classification number: A61B5/02108 , A61B5/0002 , A61B5/0031 , A61B5/0205 , A61B5/021 , A61B5/02125 , A61B5/0261 , A61B5/0402 , A61B5/08 , A61B5/686 , A61B5/746
Abstract: The exemplary systems and methods may monitor one or more signals to be used to assess the hemodynamic status of a patient. The one or more signals may be used to calculate, or determine, a plurality of pulse transit times. The plurality of pulse transit times may be used to determine hemodynamic status values that may be indicative of a patient's aggregate hemodynamic status.
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10.发明申请公开(公告)号：US20160317817A1
公开(公告)日：2016-11-03
申请号：US15204464
申请日：2016-07-07
Applicant: Medtronic, Inc.
Inventor： Todd M. Zielinski , Yong Kyun Cho , Douglas Hettrick , Xusheng Zhang
CPC classification number: A61N1/36585 , A61B5/0535 , A61B5/0538 , A61N1/36521 , A61N1/3682 , A61N1/3684 , A61N1/3686
Abstract: Methods and/or devices used in delivering cardiac resynchronization therapy based on a plurality of device parameters (e.g., A-V delay, V-V delay, etc.) are optimized by setting a device parameter based on selection data. The selection data may be acquired by acquiring temporal fiducial points (e.g., heart sounds) associated with at least a part of a systolic portion of at least one cardiac cycle and/or temporal fiducial points associated with at least a part of a diastolic portion of the at least one cardiac cycle for each of a plurality of electrode vector configurations, and extracting measurements from the intracardiac impedance signal acquired for each of a plurality of electrode vector configurations based on the temporal fiducial points. The acquired selection data may be scored and used to optimize the device parameter.
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