公开(公告)号：US20110298166A1

公开(公告)日：2011-12-08

申请号：US13138416

申请日：2010-02-17

申请人： Hiroyuki Inoue ,  Michio Nitta ,  Taijiro Matsui ,  Tsutomu Wakasa ,  Yoshiyuki Yamagami ,  Toru Mochida

发明人： Hiroyuki Inoue ,  Michio Nitta ,  Taijiro Matsui ,  Tsutomu Wakasa ,  Yoshiyuki Yamagami ,  Toru Mochida

IPC分类号： F27B1/10 ,  C04B35/64 ,  C04B35/532

CPC分类号： C04B35/013 ,  B82Y30/00 ,  C04B35/522 ,  C04B35/528 ,  C04B35/532 ,  C04B35/806 ,  C04B2235/3206 ,  C04B2235/3217 ,  C04B2235/3222 ,  C04B2235/3244 ,  C04B2235/3418 ,  C04B2235/3463 ,  C04B2235/3817 ,  C04B2235/3843 ,  C04B2235/404 ,  C04B2235/424 ,  C04B2235/428 ,  C04B2235/5244 ,  C04B2235/5276 ,  C04B2235/5436 ,  C04B2235/5454 ,  C04B2235/80 ,  C04B2235/96 ,  C21B7/06 ,  F27D1/0006

摘要： The present invention provides a carbonaceous refractory, and a method of production of the same, which prevents a drop in the molten pig iron corrosion resistance, molten pig iron penetration resistance, and other properties of carbonaceous refractories required for blast furnace bottom refractories and, further, raises the mechanical strength of the refractories so as to suppress cracking due to thermal stress, that is, a carbonaceous refractory characterized by comprising a carbonaceous material comprised of one or more of calcined anthracite, calcined coke, natural graphite, or artificial graphite in 60 to 85 mass %, a refractory metal oxide in 5 to 15 mass %, metal silicon in 4 to 15 mass %, and carbon black in 2 to 10 mass % and by being obtained by adding an organic binder to refractory materials made a total 100 mass %, kneading the materials, then molding them and firing them in a nonoxidizing atmosphere.

摘要翻译： 本发明提供了一种碳质耐火材料及其制造方法，其防止了高炉炉底耐火材料所需的耐熔融生铁耐腐蚀性，熔融猪铁渗透阻力以及其他碳质耐火材料的性能， 提高了耐火材料的机械强度，以便抑制由于热应力引起的裂纹，即，碳质耐火材料，其特征在于，包含由60质量％以上的煅烧无烟煤，煅烧焦炭，天然石墨或人造石墨中的一种或多种构成的碳质材料 至85质量％，5〜15质量％的难熔金属氧化物，4〜15质量％的金属硅，2〜10质量％的炭黑，通过向耐火材料中添加有机粘合剂而制成总共为100质量％ 质量％，捏合材料，然后将其成型并在非氧化气氛中进行烧制。

公开(公告)号：US07914137B2

公开(公告)日：2011-03-29

申请号：US12145439

申请日：2008-06-24

申请人： Hiroyuki Inoue ,  Soichi Hiramatsu ,  Toshihiko Ujita ,  Keiichiro Tsukuda ,  Akihiro Yamanaka ,  Yasuo Kotaki ,  Sadayuki Sugama

发明人： Hiroyuki Inoue ,  Soichi Hiramatsu ,  Toshihiko Ujita ,  Keiichiro Tsukuda ,  Akihiro Yamanaka ,  Yasuo Kotaki ,  Sadayuki Sugama

IPC分类号： B41J2/175

CPC分类号： B41J2/17553 ,  B41J2/17503 ,  B41J2/17513 ,  B41J2/1752 ,  B41J2/17523 ,  B41J2/1755

摘要： An ink container for containing ink to be supplied to an ink jet head to which the ink container is detachably mountable, includes an ink supply port for supplying the ink to the ink jet head; a air vent for fluid communication with ambience; a claw-like projection provided on a first side of the ink container; a latching lever provided on a second side opposite from the ink container, the latching lever being resiliently supported on the ink container and having a latching claw.

摘要翻译： 一种用于容纳供应到墨水容器可拆卸地安装到喷墨头上的墨水的墨水容器，包括用于向喷墨头供墨的供墨口; 用于与环境流体连通的排气口; 设置在所述墨水容器的第一侧上的爪形突起; 设置在与所述墨水容器相对的第二侧上的闩锁杆，所述闩锁杆弹性地支撑在所述墨水容器上并且具有闩锁爪。

公开(公告)号：US07896494B2

公开(公告)日：2011-03-01

申请号：US12641760

申请日：2009-12-18

申请人： Hiroyuki Inoue ,  Koji Uchida

发明人： Hiroyuki Inoue ,  Koji Uchida

IPC分类号： A61B3/14 ,  A61B3/10

CPC分类号： A61B3/12

摘要： A fundus camera includes an illumination optical system including an illumination unit configured to illuminate a fundus of a subject's eye, a fundus observation photographing optical system including an image sensor and is configured to observe a fundus image, a focus index projection unit configured to project a focus index on a center region of a photographing portion of the fundus of the subject's eye, a display unit configured to display the fundus image captured by the image sensor, an enlargement unit configured to electrically enlarge the center region of the image captured by the image sensor on which the focus index is projected, an image synthesis unit configured to synthesize an output of the enlargement unit and an image output of a peripheral portion of the image captured by the image sensor, and an output unit configured to output an output of the image synthesis unit to the display unit.

摘要翻译： 眼底照相机包括照明光学系统，包括被配置为照亮被检眼的眼底的照明单元，包括图像传感器的眼底观察拍摄光学系统，并且被配置为观察眼底图像;焦点指标投影单元，被配置为投影 被摄体眼睛的眼底拍摄部分的中心区域的焦点指标，被配置为显示由图像传感器拍摄的眼底图像的显示单元，被配置为电图放大由图像拍摄的图像的中心区域的放大单元 传感器，其上投影聚焦指标的图像合成单元，被配置为合成放大单元的输出和由图像传感器捕获的图像的周边部分的图像输出的图像合成单元，以及输出单元， 图像合成单元到显示单元。

公开(公告)号：US20100244520A1

公开(公告)日：2010-09-30

申请号：US12680522

申请日：2008-09-25

申请人： Hiroyuki Inoue ,  Keisuke Shimizu ,  Daisuke Morikawa ,  Shinji Tsutsui

发明人： Hiroyuki Inoue ,  Keisuke Shimizu ,  Daisuke Morikawa ,  Shinji Tsutsui

IPC分类号： A47C7/02

CPC分类号： A47C4/54 ,  A61H9/0078 ,  A61H2201/0149

摘要： A chair type stretching apparatus in this invention comprises a seat, a backrest, a flexible sheet, a tension means, and a controller. The flexible sheet is disposed on a top of the seat to extend an entire width of the seat. The tension means is provided on the seat and is configured to apply tensional force to the flexible sheet so as to move a center of the flexible sheet toward an upper direction of the seat. The controller is configured to control the tension means in order to move the center of the flexible sheet to a vertical direction. The tension means is provided on at least one width end of the seat in order to apply the tensional force along a width direction of the seat to the flexible sheet, whereby the tension means moves the center of the flexible sheet to the vertical direction.

摘要翻译： 本发明的椅子式拉伸装置包括座椅，靠背，柔性片，张力装置和控制器。 柔性片设置在座椅的顶部以延伸座椅的整个宽度。 张力装置设置在座椅上，并且构造成向柔性片施加张力，以使柔性片的中心朝向座椅的上方移动。 控制器被配置为控制张力装置以便将柔性片材的中心移动到垂直方向。 张力装置设置在座椅的至少一个宽度端上，以便沿着座椅的宽度方向将张力施加到柔性片材上，由此张紧装置将柔性片材的中心移动到垂直方向。

公开(公告)号：US20100203027A1

公开(公告)日：2010-08-12

申请号：US12597567

申请日：2008-04-25

申请人： Kenzaburo Tani ,  Hiroyuki Inoue ,  Makoto Inoue ,  Hiroaki Kinoh ,  Mamoru Hasegawa

发明人： Kenzaburo Tani ,  Hiroyuki Inoue ,  Makoto Inoue ,  Hiroaki Kinoh ,  Mamoru Hasegawa

IPC分类号： A61K35/12 ,  C12N15/74 ,  A61K31/7088 ,  A61P43/00

CPC分类号： A61K38/195 ,  A61K38/193 ,  A61K48/00 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/10343 ,  C12N2760/18843

摘要： An objective of the present invention is to provide safe viral vectors for gene therapy that can be introduced by a simple technique and sufficiently express genes of interest in vivo. The present inventors demonstrated that anti-tumor effect can be produced when a heparin-binding cytokine such as granulocyte macrophage colony stimulating factor (GM-CSF) and a chemokine such as TARC or RANTES are expressed in vivo using a viral vector based on a negative-strand RNA virus. The present inventors also demonstrated that the protective effect of the vector is superior to that of conventional adenovirus vectors. Thus, the present invention relates to negative-strand RNA viral vectors comprising a cytokine gene and a chemokine gene. The viral vectors are suitable for treatment of cancers, in particular, metastatic cancers. The present invention also provides compositions comprising such viral vectors, and gene therapy methods using them.

摘要翻译： 本发明的目的是提供用于基因治疗的安全病毒载体，其可以通过简单的技术引入并充分表达感兴趣的基因。 本发明人证明，当使用基于阴性的病毒载体在体内表达肝素结合细胞因子如粒细胞巨噬细胞集落刺激因子（GM-CSF）和趋化因子如TARC或RANTES时可产生抗肿瘤效应 品牌RNA病毒。 本发明人还证明，载体的保护作用优于常规腺病毒载体。 因此，本发明涉及包含细胞因子基因和趋化因子基因的负链RNA病毒载体。 病毒载体适合于治疗癌症，特别是转移性癌症。 本发明还提供包含这种病毒载体的组合物，以及使用它们的基因治疗方法。

公开(公告)号：US07491739B2

公开(公告)日：2009-02-17

申请号：US11448634

申请日：2006-06-07

申请人： Masakazu Ban ,  Hiroshi Suhara ,  Masato Horiuchi ,  Noriyoshi Yamamoto ,  Hiroshi Enomoto ,  Hiroyuki Inoue

发明人： Masakazu Ban ,  Hiroshi Suhara ,  Masato Horiuchi ,  Noriyoshi Yamamoto ,  Hiroshi Enomoto ,  Hiroyuki Inoue

IPC分类号： A61K31/44 ,  C07D213/04

CPC分类号： C07D213/56 ,  C07D213/30 ,  C07D213/32 ,  C07D213/38 ,  C07D213/40 ,  C07D213/68 ,  C07D213/75 ,  C07D401/06

摘要： A purpose of the present invention is to provide TNF-α production inhibitors being useful as therapeutic agents for autoimmune diseases such as rheumatoid arthritis. Novel compounds having the structure represented by the general formula [1] or salts thereof according to the present invention have excellent TNF-α production inhibitory activities, wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantyl or the like, R3 is aryl or an unsaturated heterocycle, and “X” is oxygen or sulfer respectively.

摘要翻译： 本发明的目的是提供TNF-α产生抑制剂，其可用作自身免疫疾病如类风湿性关节炎的治疗剂。 具有本发明通式[1]所示结构或其盐的新化合物具有优异的TNF-α产生抑制活性，其中“A”为 - （NR4） - ， - （CR5R6） - 或-O- ，“B”是亚烷基或亚烯基，R 1，R 2，R 4，R 5和R 6是氢，烷基，烯基，金刚烷基等，R 3是芳基或不饱和杂环，“X”分别是氧或硫。

公开(公告)号：US20080182881A1

公开(公告)日：2008-07-31

申请号：US11893238

申请日：2007-08-15

申请人： Masakazu Ban ,  Hiroshi Suhara ,  Masato Horiuchi ,  Noriyoshi Yamamoto ,  Hiroshi Enomoto ,  Hiroyuki Inoue

发明人： Masakazu Ban ,  Hiroshi Suhara ,  Masato Horiuchi ,  Noriyoshi Yamamoto ,  Hiroshi Enomoto ,  Hiroyuki Inoue

IPC分类号： C07D211/70 ,  A61K31/44 ,  A61K31/16 ,  C07C233/01

CPC分类号： C07D213/56 ,  C07D213/30 ,  C07D213/32 ,  C07D213/38 ,  C07D213/40 ,  C07D213/68 ,  C07D213/75 ,  C07D401/06

摘要： A purpose of the present invention is to provide TNF-α production inhibitors being useful as therapeutic agents for autoimmune diseases such as rheumatoid arthritis. Novel compounds having the structure represented by the general formula [1] or salts thereof according to the present invention have excellent TNF-α production inhibitory activities, wherein A is —(NR4)—, —(CR5R6)— or —O—, B is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantyl or the like, R3 is aryl or an unsaturated heterocycle, and X is oxygen or sulfer respectively.

公开(公告)号：USD567187S1

公开(公告)日：2008-04-22

申请号：US29211624

申请日：2004-08-19

申请人： Hitoshi Oba ,  Masahiro Kawachi ,  Hiroyuki Inoue

设计人： Hitoshi Oba ,  Masahiro Kawachi ,  Hiroyuki Inoue

公开(公告)号：US07083577B2

公开(公告)日：2006-08-01

申请号：US10279104

申请日：2002-10-24

申请人： Shinji Osawa ,  Hiroyuki Inoue ,  Kazuhiro Fukuchi ,  Masahisa Tanimoto

发明人： Shinji Osawa ,  Hiroyuki Inoue ,  Kazuhiro Fukuchi ,  Masahisa Tanimoto

IPC分类号： A61B5/00 ,  A61M25/00

CPC分类号： A61M25/09 ,  A61M2025/09083

摘要： A guide wire having an elongated core wire provided with a tabular distal end portion, and a coiled wire provided on an outer circumference of the core wire, wherein the distal end portion of the core wire is provided with a cutout section or a rased section so that a diametrical cross-sectional area of the distal end portion of the core wire gradually decreases toward a distal end thereof.

公开(公告)号：US07035774B2

公开(公告)日：2006-04-25

申请号：US10228916

申请日：2002-08-28

申请人： Hiroaki Fujiwara ,  Hiroyuki Inoue ,  Masanori Yasutake ,  Yoshimasa Takeda ,  Youichi Nakamura ,  Kazumasa Okumura

发明人： Hiroaki Fujiwara ,  Hiroyuki Inoue ,  Masanori Yasutake ,  Yoshimasa Takeda ,  Youichi Nakamura ,  Kazumasa Okumura

IPC分类号： G06F11/30

CPC分类号： H04L67/125 ,  H04L67/04 ,  H04L67/34 ,  H04L67/36 ,  H04W48/08 ,  H04W48/16

摘要： A portable terminal carried by an operator of a target apparatus includes a communicating device for conducting wireless communication and a first information acquiring device for acquiring first information related to the target apparatus from the target apparatus via the communicating device. The portable terminal also includes a second information sending device for sending second information to at least one external information terminal via the communicating device based on the first information. Further, the portable terminal includes a third information acquiring device for acquiring third information from at least one external information terminal responding to the second information via the communicating device and an information outputting device for outputting an information output based on the third information.

摘要翻译： 由目标设备的操作员携带的便携式终端包括用于进行无线通信的通信设备和用于经由通信设备从目标设备获取与目标设备相关的第一信息的第一信息获取设备。 便携式终端还包括第二信息发送装置，用于基于第一信息经由通信装置向至少一个外部信息终端发送第二信息。 此外，便携式终端包括：第三信息获取装置，用于经由通信装置从响应于第二信息的至少一个外部信息终端获取第三信息;以及信息输出装置，用于输出基于第三信息输出的信息。