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公开(公告)号：US20120171208A1
公开(公告)日：2012-07-05
申请号：US13410573
申请日：2012-03-02
申请人： Hilary Clark , Daniel L. Eaton , Bernd Wranik , Wenjun Ouyang , Lino Gonzalez , Austin L. Gurney , Kelly Loyet
发明人： Hilary Clark , Daniel L. Eaton , Bernd Wranik , Wenjun Ouyang , Lino Gonzalez , Austin L. Gurney , Kelly Loyet
CPC分类号： C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related disease.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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公开(公告)号：US20090022713A1
公开(公告)日：2009-01-22
申请号：US12180427
申请日：2008-07-25
申请人： Hilary Clark , Daniel L. Eaton , Bernd Wranik , Wenjun Ouyang , Lino Gonzalez , Austin L. Gurney , Kelly Loyet
发明人： Hilary Clark , Daniel L. Eaton , Bernd Wranik , Wenjun Ouyang , Lino Gonzalez , Austin L. Gurney , Kelly Loyet
IPC分类号： A61K39/395 , C07K16/00 , A61P37/00
CPC分类号： C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related disease
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法
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公开(公告)号：US20070185017A1
公开(公告)日：2007-08-09
申请号：US10533069
申请日：2003-10-28
申请人： Sudeepta Aggarwal , Hilary Clark , Austin Gurney , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
发明人： Sudeepta Aggarwal , Hilary Clark , Austin Gurney , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/463
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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54.发明申请Compositions and methods for the treatmetn of natural killer cell related diseases 审中-公开用于治疗自然杀伤细胞相关疾病的组合物和方法公开(公告)号：US20070037148A1
公开(公告)日：2007-02-15
申请号：US10533416
申请日：2003-11-06
申请人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
发明人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
CPC分类号： G01N33/54353 , B01J19/0046 , B01J2219/00378 , B01J2219/00385 , B01J2219/00427 , B01J2219/00529 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/00722 , B82Y30/00 , C03C17/3405 , C12Q1/6837 , C40B40/06 , C40B60/14 , G01N33/6893 , G01N2800/24
摘要： Compositions and methods for improving detection sensitivity in nucleic acid microarray analysis are disclosed, including methods of purifying nucleic acids, methods of synthesizing fluorescent DNA probes, methods of hybridization, and methods of activating a substrate for target molecule attachment are disclosed.
摘要翻译： 公开了用于提高核酸微阵列分析中检测灵敏度的组合物和方法，包括纯化核酸的方法，合成荧光DNA探针的方法，杂交方法和激活靶分子连接底物的方法。
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55.发明申请公开(公告)号：US20060199181A1
公开(公告)日：2006-09-07
申请号：US10527100
申请日：2003-09-10
申请人： Sarah Bodary , Hilary Clark , Brisdell Hunte , Janet Jackman , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
发明人： Sarah Bodary , Hilary Clark , Brisdell Hunte , Janet Jackman , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
CPC分类号： C07K14/435
摘要： Compositions and methods for improving detection sensitivity in nucleic acid microarray analysis are disclosed, including methods of purifying nucleic acids, methods of synthesizing fluorescent DNA probes, methods of hybridization, and methods of activating a substrate for target molecule attachment are disclosed.
摘要翻译： 公开了用于提高核酸微阵列分析中检测灵敏度的组合物和方法，包括纯化核酸的方法，合成荧光DNA探针的方法，杂交方法和激活靶分子连接底物的方法。
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公开(公告)号：US20060177904A1
公开(公告)日：2006-08-10
申请号：US11395249
申请日：2006-04-03
申请人： Kenneth Jacobs , John McCoy , Edward LaVallie , Lisa Collins-Racie , David Merberg , Michael Agostino , Robert Steininger , Vikki Spaulding , Gordon Wong , Hilary Clark , Kim Fechtel , Cheryl Evans , Maurice Treacy
发明人： Kenneth Jacobs , John McCoy , Edward LaVallie , Lisa Collins-Racie , David Merberg , Michael Agostino , Robert Steininger , Vikki Spaulding , Gordon Wong , Hilary Clark , Kim Fechtel , Cheryl Evans , Maurice Treacy
CPC分类号： C07K16/18 , A61K38/00 , C07K14/435 , C07K14/47
摘要： Novel polynucleotides and the proteins encoded thereby are disclosed.
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57.发明申请Achaete-scute like-2 polypeptides and encoding nucleic acids and methods for the diagnosis and treatment of tumor 审中-公开Achaete-scute like-2多肽和编码核酸和用于诊断和治疗肿瘤的方法公开(公告)号：US20050260634A1
公开(公告)日：2005-11-24
申请号：US11085775
申请日：2005-03-21
申请人： Daryl Baldwin , Hilary Clark , Adrian Jubb , Hartmut Koeppen , Clifford Quan , Thomas Wu , Zemin Zhang
发明人： Daryl Baldwin , Hilary Clark , Adrian Jubb , Hartmut Koeppen , Clifford Quan , Thomas Wu , Zemin Zhang
IPC分类号： A61K38/00 , C07K14/47 , C12Q1/68 , C07H21/04 , C07K14/82 , C07K16/30 , C12N15/09 , G01N33/574
CPC分类号： C07K14/4748 , C07K14/47 , C07K14/82
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same
摘要翻译： 本发明涉及可用于哺乳动物肿瘤诊断和治疗的物质组合物以及使用这些物质组合物的方法
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公开(公告)号：US07605229B2
公开(公告)日：2009-10-20
申请号：US11557256
申请日：2006-11-07
申请人： Hilary Clark , Daniel L. Eaton , Austin L. Gurney , Bernd Wranik
发明人： Hilary Clark , Daniel L. Eaton , Austin L. Gurney , Bernd Wranik
IPC分类号： C07K14/435 , C07K16/46
CPC分类号： C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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公开(公告)号：US20090186034A1
公开(公告)日：2009-07-23
申请号：US12004525
申请日：2007-12-19
申请人： Alexander Abbas , Hilary Clark , Lauri Diehl
发明人： Alexander Abbas , Hilary Clark , Lauri Diehl
IPC分类号： C12Q1/68 , A61K31/4402 , A61K31/195 , A61K31/196 , A61K31/58 , A61K31/573 , A61K31/52 , A61K31/519 , A61K38/13 , A61K39/395
CPC分类号： C12Q1/6883 , A61K31/195 , A61K31/196 , A61K31/4402 , A61K31/519 , A61K31/52 , A61K31/573 , A61K31/58 , C12Q2600/106 , C12Q2600/112 , C12Q2600/158
摘要： The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
摘要翻译： 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。
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60.发明申请公开(公告)号：US20080038264A1
公开(公告)日：2008-02-14
申请号：US11537311
申请日：2006-09-29
申请人： Sarah Bodary , Hilary Clark , Brisdell Hunte , Janet Jackman , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
发明人： Sarah Bodary , Hilary Clark , Brisdell Hunte , Janet Jackman , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
IPC分类号： A61K39/395 , A61K35/00 , A61P37/00 , C07K14/00 , C12N1/00 , C12N1/21 , C12N5/06 , C12Q1/02 , G01N33/53 , G01N33/68 , C12Q1/68 , C12P21/00 , C12N15/63 , C12N1/19 , C07K16/00 , C07H21/00 , A61K38/16
CPC分类号： G01N33/564 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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