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    Implantable medical device with anti-infection agent
    51.
    发明授权
    Implantable medical device with anti-infection agent 失效
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US07596408B2

    公开(公告)日：2009-09-29

    申请号：US10837319

    申请日：2004-04-30

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device with anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 具有抗感染剂的可植入医疗器械。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT
    53.
    发明申请
    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT 有权
    具有抗感染剂的可植入医疗器械

    公开(公告)号：US20090292327A1

    公开(公告)日：2009-11-26

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Implantable medical device with lubricious material
    54.
    发明授权
    Implantable medical device with lubricious material 有权
    具有光滑材料的植入式医疗器械

    公开(公告)号：US09162072B2

    公开(公告)日：2015-10-20

    申请号：US11526514

    申请日：2006-09-25

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/375 ,  A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/375 ,  A61B2560/0443 ,  A61N1/0526 ,  A61N1/3605

    摘要： An implantable medical device with lubricious material permits implantable medical devices to have a reduced friction between the device and at least a portion of the surrounding tissue. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the tissue. The lubricious material may be provided on or impregnated in the housing or the member. In some embodiments, the device is configured for implantation in the head of a human body. In other embodiments, the device is configured for implantation between the cranium and the scalp. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled together to provide a smaller profile.

    摘要翻译： 具有润滑材料的可植入医疗装置允许植入式医疗装置在装置与周围组织的至少一部分之间具有减小的摩擦。 可植入医疗装置可以具有壳体，或者可以具有壳体和用于在装置和组织之间提供平滑界面的构件。 润滑材料可以设置在或浸渍在壳体或构件中。 在一些实施例中，该装置被配置用于植入人体的头部。 在其他实施例中，该装置被配置用于在颅骨和头皮之间植入。 在一些实施例中，设备包括单个模块，而在其他实施例中，多个模块耦合在一起以提供较小的轮廓。

    MEDICAL DEVICE BATTERY ENCLOSURE
    55.
    发明申请
    MEDICAL DEVICE BATTERY ENCLOSURE 有权
    医疗器械电池外壳

    公开(公告)号：US20130196214A1

    公开(公告)日：2013-08-01

    申请号：US13749747

    申请日：2013-01-25

    申请人： Erik R. Scott ,  Prabhakar A. Tamirisa

    发明人： Erik R. Scott ,  Prabhakar A. Tamirisa

    IPC分类号： H01M2/02

    CPC分类号： H01M2/022 ,  H01M2/0202 ,  H01M2/0287 ,  H01M10/052 ,  H01M2220/30

    摘要： In one example, the disclosure is directed to a medical device comprising an outer housing and a battery within the outer housing, where the battery is configured to supply power to one or more electronic components of the medical device. The battery comprises a first electrode, a second electrode, an electrolyte, and a multilayer battery enclosure. The multilayer battery enclosure comprises a substantially cylindrical member including a continuous multilayer body defining a cavity between a first end and a second end, and wherein at least one of the first end and second end are sealed to enclose the first electrode, second electrode, and the electrolyte within the cavity of the multilayer battery enclosure.

    摘要翻译： 在一个示例中，本公开涉及一种医疗装置，其包括在外壳内的外壳和电池，其中电池被配置为向医疗装置的一个或多个电子部件供电。 电池包括第一电极，第二电极，电解质和多层电池外壳。 多层电池外壳包括基本上圆柱形的构件，其包括在第一端和第二端之间限定空腔的连续多层体，并且其中第一端部和第二端中的至少一个被密封以包围第一电极，第二电极和 多层电池外壳内的电解液。

    Implantable medical device with anti-infection agent
    57.
    发明授权
    Implantable medical device with anti-infection agent 有权
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US08086313B2

    公开(公告)日：2011-12-27

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Concavity of an implantable medical device
    58.
    发明授权
    Concavity of an implantable medical device 有权
    可植入医疗器械的凹陷

    公开(公告)号：US07529586B2

    公开(公告)日：2009-05-05

    申请号：US10731867

    申请日：2003-12-09

    申请人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Ruchika Singhal ,  Robert M. Skime ,  Erik R. Scott ,  James E. Randall

    发明人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Ruchika Singhal ,  Robert M. Skime ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/36

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

    摘要： At least one surface of an implantable medical device is concave along at least one axis such that it substantially conforms to a surface within a patient, such as the cranium, when it is implanted on that surface. In some embodiments, the surface of the implantable medical device substantially conforms to an arc with a radius that is between 4.5 and 9.5 centimeters, and is preferably approximately equal to 7 centimeters. In some embodiments, the implantable medical device comprises a plurality of interconnected modules, and an overmold that at least partially encapsulates each of the modules. In such embodiments, at least one surface of the overmold is concave along at least one axis. Further, each of the modules of such an implantable medical device may comprise a housing, and at least one surface of at least one of the housings may be concave along at least one axis.

    摘要翻译： 可植入医疗装置的至少一个表面沿着至少一个轴线是凹形的，使得当植入在该表面上时，其基本上符合患者（例如颅骨）内的表面。 在一些实施例中，可植入医疗装置的表面基本上符合半径在4.5和9.5厘米之间的弧度，并且优选地大约等于7厘米。 在一些实施例中，可植入医疗装置包括多个互连的模块，以及至少部分地封装每个模块的包覆模制。 在这样的实施例中，包覆模制体的至少一个表面沿着至少一个轴线是凹形的。 此外，这种可植入医疗装置的每个模块可以包括壳体，并且至少一个壳体的至少一个表面沿着至少一个轴线可以是凹形的。

    Electrochemically reactive cathodes for an electrotransport device
    60.
    发明授权
    Electrochemically reactive cathodes for an electrotransport device 有权
    用于电输送装置的电化学反应阴极

    公开(公告)号：US06505069B2

    公开(公告)日：2003-01-07

    申请号：US09239233

    申请日：1999-01-28

    申请人： Erik R. Scott ,  Lothar W. Kleiner

    发明人： Erik R. Scott ,  Lothar W. Kleiner

    IPC分类号： A61N130

    CPC分类号： A61N1/0436 ,  A61N1/044 ,  Y10T29/49988 ,  Y10T29/49991

    摘要： The present invention relates generally to improved cathodes (24) for use in an electrotransport device (10) for transdermally or transmucosally delivering a beneficial agent (e.g., a drug) to, or extracting a body analyte (e.g., glucose) from, the body surface of a patient. Most particularly, the present invention relates to a cathodic electrode (24) in the form of a silver halide foil which can be made, e.g., by forging particulate silver chloride. The cathode (24) does not absorb agent (e.g., drug), eliminates the need for binders, solvents and processing aids during the manufacturing process, and increases dimensional freedom of design.

    摘要翻译： 本发明一般涉及用于电转运装置（10）中的改进的阴极（24），用于经皮或经粘膜递送有益药物（例如药物）或从体内提取身体分析物（例如葡萄糖） 患者的表面。 最具体地说，本发明涉及卤化银箔形式的阴极电极（24），其可以例如通过锻造颗粒状氯化银制成。 阴极（24）不吸收剂（例如药物），在制造过程中不需要粘合剂，溶剂和加工助剂，并增加了设计的尺寸自由度。