公开(公告)号：US07002162B1

公开(公告)日：2006-02-21

申请号：US10344850

申请日：2000-08-18

申请人： Masatoshi Fujimoto ,  Shinichiro Aoshima ,  Makoto Hosoda ,  Yutaka Tsuchiya

发明人： Masatoshi Fujimoto ,  Shinichiro Aoshima ,  Makoto Hosoda ,  Yutaka Tsuchiya

IPC分类号： G01N21/64

CPC分类号： G01N21/6408 ,  G01N21/6445

摘要： A fluorescence component that passes through a region of a detection medium where a change in refractive index has been induced through a nonlinear optical effect produced in the detection medium by a gate pulse is observed as a fluorescence image by utilizing a change in polarization state. By observing the change in position of the fluorescence image while correlating with the change over time in the fluorescence, a fluorescence lifetime measuring apparatus is realized with which the change over time in the fluorescence, in particular the fluorescence lifetime, can be measured efficiently with high temporal resolution.

摘要翻译： 通过利用偏振状态的变化，通过在检测介质中通过栅极脉冲产生的非线性光学效应，通过检测介质的区域的折射率变化的荧光成分被观察为荧光图像。 通过观察荧光图像的位置变化，同时与荧光中随时间的变化相关联，实现了荧光寿命测量装置，其中荧光寿命随时间的变化，特别是荧光寿命可以高效地测量 时间分辨率。

公开(公告)号：US20060013269A1

公开(公告)日：2006-01-19

申请号：US10533441

申请日：2003-12-19

申请人： Hironori Takahashi ,  Takashi Inoue ,  Shinji Ohsuka ,  Yutaka Tsuchiya

发明人： Hironori Takahashi ,  Takashi Inoue ,  Shinji Ohsuka ,  Yutaka Tsuchiya

IPC分类号： H01S3/10

CPC分类号： G21G1/12 ,  A61N2005/1088 ,  H05H6/00

摘要： The present invention relates to a high-speed particle generating method and so on for generating high-speed particles from a high-speed particle generating target by condensing a pulsed laser beam to a micro-spot on the surface of a high-speed particle generating target. The high-speed particle generating method is a method that generates high-speed particles by condensing a pulsed laser beam generated from a pulsed laser beam generator through an irradiation optical system at a predetermined condensing point, and irradiating the pulsed laser beam to the high-speed particle generating target that is set at the predetermined condensing point, the method including a first step of preparing a reference data, a second step of measuring the wave front of the pulsed laser beam, and a third step of compensating the wave front of the pulsed laser beam based on the reference data.

摘要翻译： 本发明涉及一种高速粒子产生方法等，用于通过将脉冲激光束与高速粒子产生的表面上的微点集中而从高速粒子产生靶产生高速粒子 目标。 高速粒子产生方法是通过在脉冲激光束发生器产生的脉冲激光束通过照射光学系统在预定的聚光点聚光并将脉冲激光束照射到高速粒子发生方法， 设定在所述规定的聚光点的高速粒子产生目标，所述方法包括准备基准数据的第一步骤，测量所述脉冲激光束的波前的第二步骤，以及补偿所述脉冲激光束的波前的第三步骤， 基于参考数据的脉冲激光束。

公开(公告)号：US06965421B2

公开(公告)日：2005-11-15

申请号：US10639493

申请日：2003-08-13

申请人： Yutaka Tsuchiya

发明人： Yutaka Tsuchiya

IPC分类号： G02F1/1333 ,  G02F1/1337 ,  G02F1/1368

CPC分类号： G02F1/133788

摘要： A liquid crystal device, in which an orientation film does not deteriorate over time, contrast decreases slightly during longterm use, the axial orientation in the horizontal direction is high, and superior display quality is exhibited, and electronic equipment therewith are disclosed. A liquid crystal light valve employing a liquid crystal device is also disclosed, in which a pair of substrates facing each other; a liquid crystal layer interposed between the pair of substrates; an electrode formed on each of the substrates; and an orientation film formed on the surface of each of the electrodes are provided on the surface 15 of the substrate body 10A, plural grooves 16 are formed in parallel, in each of the grooves, concave-convex portions 10a are formed, which periodically vary along an axial orientation direction Ax of the liquid crystal and have a sawtoothed cross-sectional form along the direction Ax, and between an opening 16a of the groove 16 and each of the top parts 18 of the concave-convex portions 10a, a height difference G is provided.

摘要翻译： 其中取向膜不会随着时间而劣化的液晶装置，长期使用中的对比度稍微降低，水平方向上的轴向取向高，并且显示出优异的显示质量，并且公开了电子设备。 还公开了一种采用液晶装置的液晶光阀，其中一对基板彼此面对; 夹在所述一对基板之间的液晶层; 形成在每个基板上的电极; 并且在基板主体10A的表面15上设置形成在每个电极的表面上的取向膜，多个槽16平行地形成，在每个槽中形成有凹凸部10a，其中 周期性地沿着液晶的轴向取向方向Ax变化，并且沿着方向Ax具有锯齿状横截面形状，并且在凹槽16的开口16a和凹凸部10a的顶部18之间 提供了高度差G。

公开(公告)号：US06844905B2

公开(公告)日：2005-01-18

申请号：US10305985

申请日：2002-11-29

申请人： Shuhei Yamada ,  Yutaka Tsuchiya

发明人： Shuhei Yamada ,  Yutaka Tsuchiya

IPC分类号： G02F1/13 ,  G02F1/1337

CPC分类号： G02F1/133711 ,  G02F2001/133715 ,  G02F2001/133726 ,  Y10T428/10 ,  Y10T428/1005 ,  Y10T428/1023

摘要： The invention provides an alignment film that is provided with a high alignment control force to a target molecule and less likely to cause problems to an element during the formation of the alignment film. An alignment film has a configuration in which, on a first alignment layer, a second alignment film layer that is uniform in the in-plane anisotropy more than the first alignment film thereof and aligned along surface alignment of the first alignment film. The first alignment film layer can be formed of, for instance, a polyimide film whose rubbing density is 200 or less, and the second alignment film layer can be formed by use of an ion deposition method with an acryl monomers as a deposition material. A liquid crystal device provided with the alignment film like this becomes higher in the alignment control force to a liquid crystal.

摘要翻译： 本发明提供了一种对准膜，其向目标分子提供高取向控制力，并且在形成取向膜期间不易引起元件问题。 取向膜具有这样的结构，其中在第一取向层上具有比其第一取向膜大的面内各向异性均匀且与第一取向膜的表面取向对准的第二取向膜层。 第一取向膜层可以由例如摩擦密度为200以下的聚酰亚胺膜形成，第二取向膜层可以使用以丙烯酸类单体作为沉积材料的离子沉积法形成。 设置有这样的取向膜的液晶装置在对液晶的取向控制力中变得更高。

公开(公告)号：US06240305B1

公开(公告)日：2001-05-29

申请号：US09359750

申请日：1999-07-23

申请人： Yutaka Tsuchiya

发明人： Yutaka Tsuchiya

IPC分类号： A61B500

CPC分类号： G01N21/49

摘要： A method characterized by making modulated light having a predetermined modulation frequency component, incident to a scattering medium, receiving the modulated light having propagated inside the scattering medium to acquire measurement signals, detecting signals of the foregoing modulation frequency component from the measurement signals, obtaining amplitudes and inclinations of phase against modulation angular frequency, of the signals of the foregoing modulation frequency component, calculating a difference between absorption coefficients being primary information, based on a predetermined relation among the amplitudes, the inclinations of phase against modulation angular frequency and the difference between absorption coefficients, and calculating a difference of concentration of an absorptive constituent being secondary information, based on the difference between absorption coefficients.

摘要翻译： 一种方法，其特征在于使具有预定调制频率分量的调制光入射到散射介质，接收在散射介质内传播的调制光以获得测量信号，从测量信号中检测上述调制频率分量的信号，获得幅度 和相对于调制角频率的倾斜相对于前述调制频率分量的信号，基于幅度之间的预定关系，相位与调制角频率的倾斜度以及相位调制角频率之间的差异来计算作为主信息的吸收系数之间的差异 吸收系数，并且基于吸收系数之差来计算作为次级信息的吸收成分的浓度差。

公开(公告)号：US5640247A

公开(公告)日：1997-06-17

申请号：US353202

申请日：1994-12-01

申请人： Yutaka Tsuchiya ,  Kazuyoshi Ohta ,  Tsuneyuki Urakami

发明人： Yutaka Tsuchiya ,  Kazuyoshi Ohta ,  Tsuneyuki Urakami

IPC分类号： G01N33/72 ,  A61B5/145 ,  A61B5/1455 ,  G01J1/00 ,  G01N21/17 ,  G01N21/49 ,  G01N21/47 ,  A61B5/00 ,  A61B6/00 ,  G01N21/00

CPC分类号： G01N21/49

摘要： Light having a predetermined wavelength and various incident angle components to be incident on a surface of a scattering medium to generate an equivalent point light source or a group of equivalent point light sources near or on the surface of the scattering medium, and light diffused during propagation in the scattering medium is detected outside, and considering isotropic light from the equivalent light sources is immediately diffused, the optically detected signal is processed to detect a predetermined parameter which is primary information and this predetermined parameter is processed to measure internal information which is secondary information in the scattering medium with high accuracy.

摘要翻译： 具有预定波长的光和入射到散射介质的表面上的各种入射角分量的光，以在散射介质的表面附近或表面上产生等效点光源或一组等效点光源，以及在传播期间漫射的光 在散射介质外部检测到，考虑到来自等效光源的各向同性光立即扩散，对光检测信号进行处理，以检测作为主要信息的预定参数，并且处理该预定参数以测量作为次要信息的内部信息 在散射介质中具有高精度。

公开(公告)号：US5491329A

公开(公告)日：1996-02-13

申请号：US353358

申请日：1994-12-02

申请人： Tsuneyuki Urakami ,  Yutaka Tsuchiya

发明人： Tsuneyuki Urakami ,  Yutaka Tsuchiya

IPC分类号： G01J1/00 ,  A61B5/00 ,  G01J1/42 ,  G01J1/44 ,  G01J11/00 ,  G01N21/17 ,  G01N21/49 ,  G01J1/32

CPC分类号： G01N21/49 ,  A61B5/0059

摘要： Light the intensity of which is modulated to the initial intensity by a modulating signal having an ac component with a predetermined frequency and which is from the intensity tuneable light irradiating unit irradiates the scattering and absorption medium which is an object to be measured. The modulated light incident on the scattering and absorption medium propagates in the scattering and absorption medium, emerges therefrom and is incident to the photodetecting unit, and the photodetecting unit converts the incident light into an electric signal corresponding to the intensity of the incident light, and thereafter, outputs the electric signal as an optically detected signal. The feedback unit extracts the ac component from the input optically detected signal, and the intensity of the ac electric signal and the adjusting value are compared and the variation of the quantity of generating light is sent to the intensity tuneable light irradiating unit. Then, the phase difference detection is performed as the gain of the photodetecting means is fixed and the intensity of the ac component having a modulation frequency emitted from the photodetecting means is maintained so as to substantially match with the preset adjusting value.

摘要翻译： 通过具有预定频率的交流分量并且来自强度可调光照射单元的调制信号将其强度调制到初始强度的光照射作为待测对象的散射和吸收介质。 入射在散射和吸收介质上的调制光在散射和吸收介质中传播，从中出射并入射到光电检测单元，光电检测单元将入射光转换成与入射光强度对应的电信号， 此后，作为光检测信号输出电信号。 反馈单元从输入的光检测信号中提取ac分量，并且比较ac电信号和调整值的强度，并将发光量的变化发送到强度可调光照射单元。 然后，随着光检测装置的增益被固定，并且保持从光检测装置发射的调制频率的交流分量的强度，使其与预设的调整值基本一致，进行相位差检测。

公开(公告)号：US5306720A

公开(公告)日：1994-04-26

申请号：US811698

申请日：1991-12-20

申请人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Yutaka Tsuchiya ,  Hiroyuki Sugumi ,  Kunizou Higurashi ,  Norio Karibe ,  Yoshiharu Yamanishi ,  Hiroo Ogura ,  Shin Araki ,  Atsuhiko Kubota ,  Michiko Ohtake ,  Kiyomi Tamatsu

发明人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Yutaka Tsuchiya ,  Hiroyuki Sugumi ,  Kunizou Higurashi ,  Norio Karibe ,  Yoshiharu Yamanishi ,  Hiroo Ogura ,  Shin Araki ,  Atsuhiko Kubota ,  Michiko Ohtake ,  Kiyomi Tamatsu

IPC分类号： A61K31/44 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/4465 ,  A61K31/451 ,  A61K31/495 ,  A61K31/505 ,  A61P21/00 ,  A61P25/02 ,  A61P25/18 ,  A61P25/28 ,  A61P43/00 ,  C07D211/00 ,  C07D211/14 ,  C07D211/22 ,  C07D211/26 ,  C07D211/32 ,  C07D211/70 ,  C07D211/94 ,  C07D213/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D471/04 ,  C07D487/04 ,  C12N9/99

CPC分类号： C07D401/06 ,  C07D211/22 ,  C07D211/26 ,  C07D401/12 ,  C07D401/14 ,  C07D471/04 ,  C07D487/04

摘要： A novel piperidine derivative is defined by the formula (I), including a salt thereof, ##STR1## wherein R.sup.1 denotes a univalent group derived from substituted or unsubstituted quinazolinedione,X denotes a group of the formula ##STR2## n is an integer of 1 through 7, the ring A denotes a group of the formula ##STR3## a group of the formula ##STR4## or a group of the formula ##STR5## and R.sup.2 denotes a hydrogen atom, a lower alkyl group, a substituted benzoyl group, a pyridyl group, a 2-hydroxyethyl group, a pyridylmethyl group, or a group of the formula ##STR6## wherein Z represents a halogen atom). The novel compounds of this invention are used for treating dementias and sequelae of cerebrovascular diseases.

摘要翻译： 新颖的哌啶衍生物由式（I）定义，包括其盐，其中R 1表示衍生自取代或未取代的喹唑啉二酮的一价基团，X表示下式的基团：n是 1〜7的整数，环A表示式“IMAGE”的基团，即式（IMAGE）的基团或式（IMAGE）的基团，R 2表示氢原子，低级烷基，取代的苯甲酰基 基团，吡啶基，2-羟基乙基，吡啶基甲基或下式的基团，其中Z表示卤素原子）。 本发明的新化合物用于治疗脑血管疾病的痴呆和后遗症。

公开(公告)号：US5270852A

公开(公告)日：1993-12-14

申请号：US744501

申请日：1991-08-14

申请人： Yutaka Tsuchiya ,  Katsuyuki Kinoshita

发明人： Yutaka Tsuchiya ,  Katsuyuki Kinoshita

IPC分类号： G02F1/35 ,  G02F1/29 ,  G03B39/06 ,  G02B26/08 ,  G02F1/01

CPC分类号： G02F1/293

摘要： An optical shutter-camera includes a first optical unit, a deflecting unit, and a second optical unit. The first optical unit receives image rays from a subject and outputs first optical image rays to form a first optical image of the subject. The deflecting unit includes a deflection member and a pumping unit. The deflection member is a nonlinear optical material whose refractive index is varied by beam radiation. The pumping unit radiates a pumping beam having a variable intensity to a required region of the deflection member and varies the refractive index of the required region to variably deflect optical paths of the first optical image rays. The deflection unit is positioned so that a deflection center of the optical paths of the first optical image rays, formed when the variable intensity-pumping beam in incident on the deflection member, substantially agree with a position where the first optical image is formed. The second optical unit receives the first optical image rays from the deflection unit and outputs second optical image rays to form a second optical image of the subject. The second optical unit includes an aperture. The aperture restricts one of the first optical image rays and the second optical image rays.

公开(公告)号：US4994663A

公开(公告)日：1991-02-19

申请号：US355608

申请日：1989-05-23

申请人： Shinichiro Aoshima ,  Tsuneyuki Urakami ,  Yutaka Tsuchiya

发明人： Shinichiro Aoshima ,  Tsuneyuki Urakami ,  Yutaka Tsuchiya

IPC分类号： G02F3/00 ,  G01J1/00 ,  G01J11/00 ,  G06E3/00

CPC分类号： G01J11/00 ,  G06E3/005

摘要： An apparatus for measuring an autocorrelation wavaeform of intensity of input light comprises a beam splitting means for dividing the input light into two light beams, a photoelectric converter for converting one of the divided beams into an electrical signal, an optical modulating means for modulating the other light beam in accordance with the electrical signal, a delay means for varying a relative delay time between arrival times to the optical modulating means of the light beam and the electrical signal, and a photodetector having a response speed faster than that of the delay time variation for detecting output light from the optical modulating means.