公开(公告)号：US11998682B2

公开(公告)日：2024-06-04

申请号：US15711257

申请日：2017-09-21

申请人： Altria Client Services LLC

发明人： Michel Thorens

IPC分类号： A24F40/40 ,  A24D1/20 ,  A24F40/00 ,  A24F40/30 ,  A24F40/42 ,  A61M11/00 ,  A61M11/04 ,  A61M15/00 ,  A61M15/06 ,  H05B6/10 ,  A24D1/02 ,  A24D3/17 ,  A24F40/10 ,  A24F40/20 ,  B05B7/24

CPC分类号： A61M15/003 ,  A24D1/20 ,  A24F40/00 ,  A24F40/30 ,  A24F40/40 ,  A24F40/42 ,  A61M11/003 ,  A61M11/042 ,  A61M15/06 ,  H05B6/108 ,  A24D1/02 ,  A24D3/17 ,  A24F40/10 ,  A24F40/20 ,  A61M15/0003 ,  A61M15/0021 ,  A61M15/0035 ,  A61M15/0066 ,  A61M2205/0211 ,  A61M2205/3606 ,  A61M2205/3646 ,  A61M2205/368 ,  A61M2205/7545 ,  A61M2205/8206 ,  B05B7/2402

摘要： The aerosol-generating system includes an aerosol-generating article with an aerosol-forming substrate, the aerosol-generating article having an outlet end and a distal end upstream from the outlet end. The system also includes an electrically operated aerosol-generating device including a housing having a cavity configured to receive the distal end of the aerosol-generating article, an electric heating element, and a heat diffuser including a non-combustible porous body for absorbing heat from the electric heating element such that, in use, air drawn through the aerosol-generating article from the distal end to the outlet end is heated by the heat absorbed in the porous body.

公开(公告)号：US20240123165A1

公开(公告)日：2024-04-18

申请号：US18396145

申请日：2023-12-26

申请人： Altria Client Services LLC

发明人： Tony REEVELL

IPC分类号： A61M11/04 ,  A24F40/30 ,  A24F40/40 ,  A24F40/42 ,  A24F40/53 ,  A61M15/00 ,  A61M15/06

CPC分类号： A61M11/042 ,  A24F40/30 ,  A24F40/40 ,  A24F40/42 ,  A24F40/53 ,  A61M15/003 ,  A61M15/0036 ,  A61M15/06 ,  A24F40/10 ,  A61M15/0003 ,  A61M15/0021 ,  A61M15/0031 ,  A61M15/004 ,  A61M15/0041 ,  A61M2202/04 ,  A61M2202/064 ,  A61M2205/121 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/27 ,  A61M2205/3317 ,  A61M2205/3653 ,  A61M2205/6018 ,  A61M2205/6027 ,  A61M2205/6036 ,  A61M2205/6045 ,  A61M2205/8206

摘要： The method includes defining a chamber withing a first housing, the chamber including a first-shaped cavity and a second-shaped cavity configured to receive a first-type consumable and a second-type consumable, respectively.

公开(公告)号：US11896758B2

公开(公告)日：2024-02-13

申请号：US17003084

申请日：2020-08-26

申请人： Altria Client Services LLC

发明人： Tony Reevell

IPC分类号： A24F47/00 ,  A61M11/04 ,  A61M15/00 ,  A61M15/06 ,  A24F40/42 ,  A24F40/30 ,  A24F40/40 ,  A24F40/53 ,  A24F40/10 ,  A24F40/20

CPC分类号： A61M11/042 ,  A24F40/30 ,  A24F40/40 ,  A24F40/42 ,  A24F40/53 ,  A61M15/003 ,  A61M15/0036 ,  A61M15/06 ,  A24F40/10 ,  A24F40/20 ,  A61M15/0003 ,  A61M15/004 ,  A61M15/0021 ,  A61M15/0031 ,  A61M15/0041 ,  A61M2202/04 ,  A61M2202/064 ,  A61M2205/121 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/27 ,  A61M2205/3317 ,  A61M2205/3653 ,  A61M2205/6018 ,  A61M2205/6027 ,  A61M2205/6036 ,  A61M2205/6045 ,  A61M2205/8206

摘要： The e-vaping device includes a first housing, a chamber defined within the first housing, a first structure and a second structure that interface with the chamber, the first structure is configured to accept at least one first-type consumable within the chamber and the second structure is configured to receive at least one second-type consumable within the chamber.

公开(公告)号：US11878110B2

公开(公告)日：2024-01-23

申请号：US17835256

申请日：2022-06-08

申请人： Impel Pharmaceuticals Inc.

发明人： Craig Frederick Kohring ,  Christopher William Fuller

IPC分类号： A61H15/00 ,  A61M15/00 ,  A61M15/08

CPC分类号： A61M15/003 ,  A61M15/0035 ,  A61M15/08 ,  A61M15/009 ,  A61M2202/04 ,  A61M2202/064 ,  A61M2205/8225 ,  A61M2206/20

摘要： A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip that removably couples to the actuator body. The actuator body comprises a propellant channel in fluid communication with a propellant canister. The tip comprises an exit channel, an inlet interface, one or more grooves, and an outlet orifice. The exit channel extends between a proximal end and a distal end of the tip. The inlet interface is positioned about a distal end of the exit channel, and the inlet interface couples to a compound container containing the compound. The grooves are positioned about the inlet interface and direct propellant from the propellant channel into the compound container, thereby agitating and entraining the compound in the compound container with the released propellant. The compound and the propellant then travel through the exit channel and out the outlet orifice.

公开(公告)号：US11844900B1

公开(公告)日：2023-12-19

申请号：US18224502

申请日：2023-07-20

申请人： MICRONEB TECH HOLDINGS, INC.

发明人： Pradeep Albert ,  Christine Nichols ,  David J. Condron ,  Brian Artze ,  Fadi Saba ,  Jesse Klein ,  Vijay Vad

IPC分类号： A61M16/00 ,  A61M11/00 ,  A61M15/00 ,  A61M16/06

CPC分类号： A61M16/0084 ,  A61M11/005 ,  A61M15/003 ,  A61M16/06 ,  A61M2205/82

摘要： A method is disclosed for administering medication to conscious or unconscious patients using a device with a tubular chamber. The method involves the use of a device with a tubular chamber, wherein a liquid medication is contained within a capsule. The medication is atomized by activating an atomizer, thereby generating an atomized medication consisting of particles with a maximum diameter of four microns. The atomized medication is then dispensed into the tubular chamber. Using the device, the atomized medication is administered to the patient. In cases of unconsciousness, a resilient air bladder connected to the chamber is partially deflated, allowing air transfer into the chamber. This facilitates the administration of the atomized medication. This method enables effective medication delivery in various emergency scenarios, ensuring appropriate treatment even for unresponsive patients by providing a method of using a device with modular components.

公开(公告)号：US20230364010A1

公开(公告)日：2023-11-16

申请号：US18357927

申请日：2023-07-24

申请人： Impel Pharmceuticals Inc.

发明人： John D. Hoekman ,  Kelsey H. Satterly ,  Inna Dashevsky ,  Aditya R. Das

IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K31/5513 ,  A61M15/00 ,  A61K31/00 ,  A61P25/18

CPC分类号： A61K9/0043 ,  A61K9/16 ,  A61K31/5513 ,  A61M15/003 ,  A61K9/1652 ,  A61K31/00 ,  A61P25/18 ,  A61K9/1623 ,  A61K9/1617

摘要： Methods are provided for acute treatment of agitation, including agitation in patients with schizophrenia or bipolar disorder, comprising administering to a subject with agitation an effective dose of a dry pharmaceutical composition comprising olanzapine, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma olanzapine concentration (Cmax) of at least 30 ng/mL, with (b) a mean time to Cmax (Tmax) of olanzapine of less than 0.5 hours. Dry pharmaceutical compositions and devices suitable for intranasal delivery of olanzapine are provided.

公开(公告)号：US11717028B2

公开(公告)日：2023-08-08

申请号：US16916573

申请日：2020-06-30

申请人： Altria Client Services LLC

发明人： Yossef Raichman

IPC分类号： A24F40/42 ,  A24F40/40 ,  A24F40/46 ,  A24F40/57 ,  A24F40/50 ,  A61M11/04 ,  A61M15/00 ,  A61P25/36 ,  A61P27/06 ,  A61P25/30 ,  A61P43/00 ,  A61P11/06 ,  A61P25/18 ,  A61P25/08 ,  A61P29/00 ,  A61P1/08 ,  A61K9/00 ,  A61K31/05 ,  A61K31/352 ,  A61K36/185 ,  A61M15/06 ,  A24F40/20 ,  A24F40/60 ,  A24F40/95 ,  A61M16/00

CPC分类号： A24F40/42 ,  A24F40/40 ,  A24F40/46 ,  A24F40/50 ,  A24F40/57 ,  A61K9/007 ,  A61K31/05 ,  A61K31/352 ,  A61K36/185 ,  A61M11/042 ,  A61M15/00 ,  A61M15/003 ,  A61M15/06 ,  A61P1/08 ,  A61P11/06 ,  A61P25/08 ,  A61P25/18 ,  A61P25/30 ,  A61P25/36 ,  A61P27/06 ,  A61P29/00 ,  A61P43/00 ,  A24F40/20 ,  A24F40/60 ,  A24F40/95 ,  A61M15/002 ,  A61M15/0021 ,  A61M2016/0024 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/8206

摘要： A method of treating disorders in a human or animal subject may include heating a material containing a compound to a first temperature to form a heated volume of the material. The method may additionally include heating the heated volume to a higher second temperature to form a dose of vapor including the compound. The method may also include administering the dose of vapor to the subject to treat disorders such as pain. The method may further include pre-heating the material to a preliminary temperature prior to the heating to the first temperature. The heating and pre-heating may be performed with a capsule including two covering layers, each including an electrically conductive material, configured to hold the material therebetween and to generate heat by resistive heating.

公开(公告)号：US11696598B2

公开(公告)日：2023-07-11

申请号：US16796253

申请日：2020-02-20

申请人： Altria Client Services LLC

发明人： Yossef Raichman

IPC分类号： A61M15/06 ,  A61M11/04 ,  A24F40/46 ,  A24F40/42 ,  A24F40/57 ,  A24F40/20 ,  A61M15/00 ,  G05D23/19 ,  A24F40/51 ,  A24F40/40 ,  A61M16/00

CPC分类号： A24F40/42 ,  A24F40/40 ,  A24F40/46 ,  A24F40/51 ,  A24F40/57 ,  A61M11/042 ,  A61M11/044 ,  A61M15/003 ,  A61M15/0063 ,  A61M15/0085 ,  A61M15/06 ,  G05D23/1904 ,  A24F40/20 ,  A61M2016/0021 ,  A61M2016/0039 ,  A61M2205/3368 ,  A61M2205/3653 ,  A61M2205/8206

摘要： Apparatus and methods are described for use with a vaporizer that vaporizes at least one active ingredient of a plant material. In response to receiving a first input to the vaporizer, the plant material is heated, in a first heating step. An indication of the temperature of the plant material is detected, and, in response to detecting an indication that the temperature of the plant material is at a first temperature, the first heating step is terminated, by withholding causing further temperature increase of the plant material. The first temperature is less than 95 percent of the vaporization temperature of the active ingredient. Subsequently, a second input is received at the vaporizer. In response thereto, the plant material is heated to the vaporization temperature, in a second heating step. Other applications are also described.

公开(公告)号：US20230181848A1

公开(公告)日：2023-06-15

申请号：US17924724

申请日：2021-05-18

申请人： PHILIP MORRIS PRODUCTS S.A.

发明人： Fiorenzo Draghetti

IPC分类号： A61M15/06 ,  A61M15/00

CPC分类号： A61M15/06 ,  A61M15/003 ,  A61M2202/064

摘要： The invention relates to a method for manufacturing an inhaler article, the inhaler article comprising a body, a capsule cavity holding a capsule, a mouthpiece element and a deformable tubular element having an open distal end, the method comprising pre-treating the distal end of the deformable tubular element to obtain a pre-treated portion with reduced structural stability, and folding the pre-treated portion inwards by at least 90 degrees to at least partially close the distal end. The invention relates also to a device for manufacturing an inhaler article and to an inhaler article obtainable by the device.

公开(公告)号：US20180304031A1

公开(公告)日：2018-10-25

申请号：US16025437

申请日：2018-07-02

申请人： Nicholas A. Havercroft ,  Donald M. Pell ,  Michael P. Spuza ,  Govindan P. Nair

发明人： Nicholas A. Havercroft ,  Donald M. Pell ,  Michael P. Spuza ,  Govindan P. Nair

IPC分类号： A61M11/00 ,  A61K9/00

CPC分类号： A61K31/465 ,  A24F47/002 ,  A61K9/0078 ,  A61M11/003 ,  A61M11/005 ,  A61M15/0021 ,  A61M15/003 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/06 ,  A61M2205/50 ,  A61M2205/584 ,  A61M2205/8206 ,  A61M2209/10

摘要： A nebulizer comprising a nebulizing chamber with a vibrating mesh grid having a plurality of precision openings and said chamber with a liquid pharmaceutical product in a cartridge contacting the mesh grid for producing particle sizes of two (2) to four (4) microns; and an entrainment port for drawing air into the nebulizing chamber and through the grid. A control circuit, a source of electrical energy in said circuit such as two 1.5 volt lithium titanate batteries connected to said grid for producing vibration. A switch to turn said grid off and on and means for providing a first measured time period of four seconds for taking a first breath of air through the entrainment port and grid and through the thousands of passageways into the lungs and bloodstream of an individual. A second time period during which no vibration occurs. The grid is also self-cleaning as described.