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公开(公告)号：US20230399407A1
公开(公告)日：2023-12-14
申请号：US18035609
申请日：2021-11-03
发明人： Sang Taek JUNG , Ji Sun LEE , Bo Mi KIM
CPC分类号： C07K16/283 , C07K16/32 , C07K2317/92 , C07K2317/31 , C07K2317/622
摘要： The present invention relates to an antibody having enhanced binding affinity for human Fc alpha receptor and a technique for maximizing a mechanism of antibody action by using same. Antibodies specific for Fc alpha receptors or immunologically active fragments thereof according to the present invention are in the form of IgG and bind to Fc alpha receptors of effector cells, especially, neutrophils, which are most abundant in mammals, thereby overcoming the disadvantages of conventional IgA antibodies and maximizing an effector function in various antibody therapeutic agents, which leads to maximizing the mechanism of antibody action (ADCC and ADCP). Thus, various Fc-fused protein therapeutic agents using same can be advantageously utilized as antibody drugs with enhanced effector functions.
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62.发明公开公开(公告)号：US20230391753A1
公开(公告)日：2023-12-07
申请号：US18032724
申请日：2021-10-19
发明人： Jae Hong Seo , Kee Dal Nam , Ji Young Kim , Yoon Jae Kim , Min Su Park , Yong Koo Kang
IPC分类号： C07D403/12 , C07D235/32 , C07D409/12 , C07D405/12 , C07D401/12 , A61P35/00
CPC分类号： C07D403/12 , C07D235/32 , A61P35/00 , C07D405/12 , C07D401/12 , C07D409/12
摘要： The present invention relates to a thiobenzimidazole derivative or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating cancer, comprising the derivative as an active ingredient. The thiobenzimidazole derivative of the present invention exhibits cell toxicity by blocking the cell cycle of a cancer cell and inducing apoptosis when administered to an individual, as the derivative inhibits tubulin polymerization by being activated in the cancer cell, and, thus, the derivative can be used for prevention or treatment of cancer, desirably for prevention or treatment of triple-negative breast cancer.
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公开(公告)号：US11836315B2
公开(公告)日：2023-12-05
申请号：US17500108
申请日：2021-10-13
发明人： Chulwoo Kim , Soonsung Ahn
IPC分类号： G06F3/041 , G06F3/046 , G06F3/044 , G06F3/0354
CPC分类号： G06F3/04162 , G06F3/03545 , G06F3/046 , G06F3/0414 , G06F3/0441 , G06F3/0442 , G06F3/04166
摘要： Disclosed is electronic device for identifying touch position, touch system including electronic device, and operation method thereof.
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公开(公告)号：US20230387340A1
公开(公告)日：2023-11-30
申请号：US18362611
申请日：2023-07-31
发明人： Yongseok JUN , Yoonmook KANG , Chanyong LEE , Kyungjin CHAE
IPC分类号： H01L31/0475 , H01L31/0224
CPC分类号： H01L31/0475 , H01L31/022425
摘要： Disclosed in the present invention is a solar module, comprising: a frame including at least three sidewalls; first solar cells each having both ends coupled to each of two sidewalls of the frame; and second solar cells intersecting the first solar cells and coupled to each of the two sidewalls of the frame.
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公开(公告)号：US11832314B2
公开(公告)日：2023-11-28
申请号：US17718564
申请日：2022-04-12
发明人： Young Chai Ko , Ju Hyung Lee
IPC分类号： H04W74/08 , H04W72/04 , H04B7/195 , H04W72/0446 , H04W84/06
CPC分类号： H04W74/085 , H04B7/195 , H04W72/0446 , H04W74/0866 , H04W84/06
摘要： A random access method for a terminal with the processor and the memory to access a low earth orbit satellite network formed by multiple low earth orbit satellites (LEO SAT) includes: the stage where a Deep Reinforcement Learning (DRL) algorithm is applied for a pre-set time to decide which one between the first and the second actions should be performed at every access cycle, and to perform the random access to the low earth orbit satellite network based on the above decision while learning it; and the stage where, according to the learning result of the DRL algorithm performed for above pre-set time, it decides which of the first and the second actions should be chosen when attempting to access the low earth orbit satellite network at a new access cycle and then to perform the random access to the low earth orbit satellite network according to the above choice.
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公开(公告)号：US11828719B2
公开(公告)日：2023-11-28
申请号：US17186675
申请日：2021-02-26
发明人： Hee-Min Kang , Chandra Khatua , Gun-Hyu Bae , Hyo-Jun Choi , Sun-Hong Min
IPC分类号： C12N5/071 , C12N11/14 , G01N27/327 , C07K14/705 , C12N5/00
CPC分类号： G01N27/3278 , C07K14/70546 , C12N5/0075 , C12N11/14 , C12N2501/40 , C12N2533/50 , G01N2203/0635
摘要： The present invention relates to a nano-ligand for promoting cell adhesion and differentiation of stem cells and a method of promoting cell adhesion and differentiation of stem cells by using the nano-ligand, and the method of promoting cell adhesion and differentiation of stem cells according to the present invention may temporally and spatially, and reversibly control nano-ligand sliding by applying a magnetic field to a substrate including the nano-ligands, and efficiently control stem cell adhesion and differentiation ex vivo or in vivo through the magnetic-field based on spatiotemporal control.
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公开(公告)号：US11817020B2
公开(公告)日：2023-11-14
申请号：US17101583
申请日：2020-11-23
发明人： Mun Pyo Hong , Sang Il Kim , Ho Won Yoon , Jeong Sik Yoon
IPC分类号： G09F9/30 , H10K50/844 , H10K71/00 , H10K77/10
CPC分类号： G09F9/301 , H10K50/844 , H10K71/00 , H10K77/111
摘要： A method of manufacturing a stretchable display according to an embodiment of the present invention includes preparing a process carrier substrate, forming a flexible substrate on the process carrier substrate, forming a light emitting layer and a driving element controlling the light emitting layer on the flexible substrate, and attaching a stretchable film divided into a low stretchable area and a high stretchable area such that at least a part of the low stretchable area covers at least a part of the driving element in a state in which the high stretchable area is stretched.
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公开(公告)号：US20230347025A1
公开(公告)日：2023-11-02
申请号：US18348247
申请日：2023-07-06
发明人： Myoung-Ryul OK , Jimin PARK , Yu Chan KIM , Hyun Kwang SEOK , Hyung-Seop HAN , Hojeong JEON , Hyunseon SEO , Jee-Wook LEE , Jin Kyung JEON , Gayoung JUNG , Jong Woong PARK , Ji Hun PARK
CPC分类号： A61L31/16 , A61B17/8605 , A61B17/80 , A61K9/0024 , A61K33/00 , A61L31/022 , F16B35/04 , A61F2/2846 , A61B17/866 , A61B2017/00893
摘要： Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.
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69.发明公开公开(公告)号：US20230342468A1
公开(公告)日：2023-10-26
申请号：US18215678
申请日：2023-06-28
发明人： Dong Hoon Lee , Wonsuk Choi , Kyungho Joo , Seyoung Lee , Aram Cho
CPC分类号： G06F21/566 , H04L12/40013 , G06F2221/034 , H04L2012/40215 , H04L2012/40273
摘要： A system and method for identifying a compromised controller using an intentional error are provided. The method, performed by an electronic device in a controller area network (CAN), for identifying a compromised electronic control unit (ECU) that transmits an attack message on a CAN bus in a periodic transmission cycle. The method includes, in response to detecting the attack message, transitioning a first ECU among a plurality of ECUs connected to the CAN bus to a bus-off state intentionally, and determining whether the first ECU is the compromised ECU based at least in part on a time, which is predicted from recovery parameters related to the first ECU, for when the first ECU resumes transmission of a CAN message and a time when the attack message is redetected on the CAN bus.
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公开(公告)号：US20230330232A1
公开(公告)日：2023-10-19
申请号：US17989940
申请日：2022-11-18
发明人： Heemin KANG , Yu-Ri KIM , Gun-Hyu BAE , Sung-Gue LEE , Na-Yeon KANG , Sun-Hong MIN , Seong-Yeol KIM
CPC分类号： A61K47/02 , A61K9/0009 , A61K45/06
摘要： Disclosed is a self-assembled complex containing an iron ion that includes an iron ion; and at least one ligand, where the iron ion and the ligand are reversibly self-assembled or self-disassembled. The iron ion and the ligand are self-assembled to form an assembly structure at least part of which is round shaped.
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