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61.
公开(公告)号:US11071812B2
公开(公告)日:2021-07-27
申请号:US15608023
申请日:2017-05-30
Applicant: Penumbra, Inc.
Inventor: Karthik Raman , Colin Yee , Chia-Hung Sze , Arthur John Lockhart , David Barry
Abstract: Doxorubicin is extracted from blood using anionic material, such as a resin comprising sulfonated polystyrene divinylbenzene beads, and polyethersulfone membrane, or both. After exposing the resin and/or membrane to blood in order to remove doxorubicin therefrom, the doxorubicin maybe extracted from the resin and/or membrane by exposing the material to an extraction solution, sonicating the extraction solution to enhance release of the doxorubicin, and repeating the exposure and sonication in order to remove substantially all of doxorubicin from the resin.
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62.
公开(公告)号:US20200367917A1
公开(公告)日:2020-11-26
申请号:US16988556
申请日:2020-08-07
Applicant: Penumbra, Inc.
Inventor: Scott Teigen , Steven Loisel , Stephen Pons , Ben Tompkins
Abstract: A vacuum aspiration control system for use with a vacuum source and an aspiration catheter includes a connecting tube configured to connect the vacuum source with a lumen of an aspiration catheter. An on-off valve is operatively coupled to the connecting tube, and a sensing unit is configured to detect flow within the connecting tube and provide a signal representative of flow. A controller receives the signal to decide whether to open or close the valve. The controller may automatically close the valve to stop flow when flow through the connecting tube is unrestricted, or according to a predetermined timing sequence. The controller can further periodically open a closed valve to determine whether flow has entered an acceptable range. The controller can still further engage pulsed aspiration with a pressure manipulation assembly when flow is restricted or occluded.
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公开(公告)号:US20200170666A1
公开(公告)日:2020-06-04
申请号:US16783872
申请日:2020-02-06
Applicant: Penumbra, Inc.
Inventor: Nicole Trosper , Holly Sit , Kathleen Lockhart , Stephany Lai
IPC: A61B17/3207
Abstract: A target substance, such as a thrombus, is removed from a patient's body via minimally invasive technique. A catheter is maneuvered and positioned near the target substance. The catheter may have a soft, atraumatic tip constructed from a metallic backbone covered by a polymer. Target substances are drawn into the catheter via an aspiration source. Near the catheter's distal end, a blade and opposing surface are housed within the catheter, and the blade moves relative to the opposing surface within the catheter lumen in order to fragment the target substance. The substances are fragmented within the catheter into discreet and relatively uniform particles. The aspiration source, which helps ensnare target substances, also serves to evacuate the substance fragments from the patient's body.
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公开(公告)号:US20190216476A1
公开(公告)日:2019-07-18
申请号:US16367060
申请日:2019-03-27
Applicant: Penumbra, Inc.
Inventor: David Barry , Arani Bose
IPC: A61B17/221 , A61B17/22
CPC classification number: A61B17/221 , A61B17/22 , A61B2017/00526 , A61B2017/22034 , A61B2017/22044 , A61B2017/2215 , A61B2217/005 , A61F2/013 , A61M2025/1052 , Y10T29/49826
Abstract: A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.
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公开(公告)号:US20180228502A1
公开(公告)日:2018-08-16
申请号:US15892732
申请日:2018-02-09
Applicant: Penumbra, Inc.
Inventor: Robyn Shaffer , Holly Sit
IPC: A61B17/22
CPC classification number: A61B17/22 , A61B2017/00309 , A61B2017/22038 , A61B2017/22039 , A61B2017/22079 , A61B2217/005 , A61M25/0053 , A61M25/0108 , A61M25/0138 , A61M2025/0008 , A61M2025/0183
Abstract: A catheter includes a shaft having a proximal end, a distal end, and a central lumen extending continuously from the proximal end to the distal end. A hypotube forms a proximal region of the shaft, and a polymer tube forms a distal region of the shaft. A periphery of the hypotube is cut in a pattern which provides a decreasing stiffness in a proximal-to-distal direction, and in some embodiments the polymer tube is reinforced by a wire embedded over at least a portion of the polymer tube's length. A guidewire lumen is disposed at or near the distal end of the catheter and extends for a portion of the catheter's length. The catheter may be used for aspiration, device delivery, or other purposes in a patient's vasculature.
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公开(公告)号:US20180197633A1
公开(公告)日:2018-07-12
申请号:US15917308
申请日:2018-03-09
Applicant: Penumbra, Inc.
Inventor: Brijesh P. Mehta
CPC classification number: G16H40/20 , A61B5/0022 , A61B5/0042 , A61B5/1113 , A61B5/681 , A61B5/74 , G06Q10/0633 , G16H20/00 , G16H40/67 , G16H50/30 , G16H70/20 , G16H80/00
Abstract: A system for treatment of ischemic stroke provides a stroke treatment workflow plan defining series of diagnostic actions and therapeutic actions to be performed at locations within a health care facility identified by beacons detectable by proximity sensors that travel with the patient. A first communications device having wireless communications capabilities receives a signal from a proximity sensor and typically transmits data to a second communications device having a visible timer and configured to receive data from and send data to other wireless communications devices. When the a patient undergoes diagnosis and treatment via the workflow plan, the system tracks the location of the patient within the workflow plan and the time at which the patient is at each location, and records the location of the patient and the time of the location within the workflow plan.
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公开(公告)号:US20170095259A1
公开(公告)日:2017-04-06
申请号:US15383241
申请日:2016-12-19
Applicant: Penumbra, Inc.
Inventor: Ben Tompkins , Arani Bose , Delilah Hui , David Barry , Stephen Pons , Aleksander Leynov
IPC: A61B17/12
CPC classification number: A61B17/12154 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12181 , A61B2017/00871 , A61B2017/12054 , A61B2017/1209
Abstract: Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.
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公开(公告)号:US20140358175A1
公开(公告)日:2014-12-04
申请号:US14460234
申请日:2014-08-14
Applicant: Penumbra, Inc.
Inventor: Ben Tompkins , Arani Bose , Delilah Hui , David Barry , Stephen Pons , Aleksander Leynov
IPC: A61B17/12
CPC classification number: A61B17/12154 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12181 , A61B2017/00871 , A61B2017/12054 , A61B2017/1209
Abstract: Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.
Abstract translation: 公开了一种栓塞线圈植入系统及其线圈可机械拆卸的方法。 线圈包括可释放地保持在植入物工具的远端内的保持元件。 植入工具可以包括构造成接合第一细丝并且当第一细丝接合时防止线圈释放的支点。 或者,推动装置和孔可以设置在植入工具的侧壁内,并且第一细丝可以与孔和侧壁一起可释放地保持线圈直到第一丝被拉出。 植入工具还可以包括用于对准第一细丝的对准构件。
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公开(公告)号:US12216820B2
公开(公告)日:2025-02-04
申请号:US18673291
申请日:2024-05-23
Applicant: Penumbra, Inc.
Inventor: William Ka-Pui Yee , Jeffrey Peter Bellinghausen
Abstract: A method for compensating for a visual impairment in a virtual reality environment, by multiple computer systems associated with a head mounted display, including, rendering an initial image for display in a virtual reality environment, determining a first visual adjustment to the HMD based on an input received by the HMD, the input being associated with a visual impairment of a user of the HMD, determining that the first visual adjustment does not satisfy a threshold measure of compensation for the visual impairment of the user, determining a second visual adjustment to the HMD, and rendering an adjusted image for display in the virtual reality environment based on the first visual adjustment and the second visual adjustment.
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70.
公开(公告)号:US20240341786A1
公开(公告)日:2024-10-17
申请号:US18750647
申请日:2024-06-21
Applicant: Penumbra, Inc.
Inventor: Nicole Trosper , Stephen Pons
CPC classification number: A61B17/22 , A61M1/75 , A61M1/76 , A61M1/77 , A61M1/774 , A61B17/00 , A61B2017/00022 , A61B2017/00561 , A61B17/32037 , A61B17/3498 , A61B90/06 , A61B2090/064 , A61B2217/005 , A61M39/105 , A61M2205/3334 , A61M2205/3344
Abstract: A platform of computing systems is configured to receive thrombectomy procedure data that is associated with a user of an aspiration thrombectomy system. The procedure data includes sets of temporal datapoints associated with a thrombectomy procedure. The platform of computing systems is further configured to generate thrombectomy analytics data based on baseline procedure data and the sets of datapoints. The platform of computing systems is further configured to visually display the thrombectomy analytics data, and to provide comparative data metrics for selection on an interactive interface.
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