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71 条记录 (耗时 0.038 秒)

    Implantable medical device and methods for automated detection of infection
    61.
    发明授权
    Implantable medical device and methods for automated detection of infection 有权
    植入式医疗设备和自动检测感染的方法

    公开(公告)号：US08583224B2

    公开(公告)日：2013-11-12

    申请号：US11833548

    申请日：2007-08-03

    申请人： Kent Lee ,  Jonathan T. Kwok ,  Hugo Andres Belalcazar ,  Jennifer Lynn Pavlovic ,  Ronald W. Heil, Jr.

    发明人： Kent Lee ,  Jonathan T. Kwok ,  Hugo Andres Belalcazar ,  Jennifer Lynn Pavlovic ,  Ronald W. Heil, Jr.

    IPC分类号： A61B5/05

    CPC分类号： A61B5/053 ,  A61B5/02405 ,  A61B5/036 ,  A61B5/0816 ,  A61B5/145 ,  A61B5/14539 ,  A61B5/412 ,  A61N1/36521

    摘要： The invention relates to systems, devices, and methods for detecting infections associated with implantable medical devices. In an embodiment, the invention includes a method of detecting infection in a patient including measuring a physiological parameter using a chronically implanted sensor at a plurality of time points and evaluating the physiological parameter measurements to determine if infection is indicated. In an embodiment, the invention includes an implantable medical device including a first chronically implantable sensor configured to generate a first signal corresponding to a physiological parameter and a controller disposed within a housing, the controller configured to evaluate the first physiological parameter signal to determine if an infection is indicated. Other embodiments are also included herein.

    摘要翻译： 本发明涉及用于检测与可植入医疗装置相关的感染的系统，装置和方法。 在一个实施例中，本发明包括检测患者感染的方法，包括在多个时间点使用长期植入的传感器测量生理参数，并评估生理参数测量以确定是否指示感染。 在一个实施例中，本发明包括可植入医疗装置，其包括被配置为产生对应于生理参数的第一信号的第一长期可植入传感器和设置在壳体内的控制器，所述控制器被配置为评估第一生理参数信号以确定是否 表示感染。 本文还包括其它实施例。

    Extendable/retractable fixation lead with distal travelling seal and related devices
    62.
    发明授权
    Extendable/retractable fixation lead with distal travelling seal and related devices 有权
    可扩展/可伸缩固定引线，远端行驶密封件和相关设备

    公开(公告)号：US08478429B2

    公开(公告)日：2013-07-02

    申请号：US13253345

    申请日：2011-10-05

    申请人： Joseph Walker ,  Ronald W. Heil, Jr. ,  G. Shantanu Reddy

    发明人： Joseph Walker ,  Ronald W. Heil, Jr. ,  G. Shantanu Reddy

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0575

    摘要： An implantable lead having a distal assembly including a coupler, a fixation helix secured to the coupler, a housing in which the fixation helix and the coupler are disposed, and a resilient seal that is fixedly secured to the coupler between proximal and distal ends thereof and able to translate with the coupler relative to the housing. The seal is positioned to sealingly engage an internal surface of the housing. When the coupler is translated such that the fixation helix is in a fully extended position, the seal is positioned to substantially seal off the housing to prevent tissue ingrowth.

    摘要翻译： 一种可植入引线，其具有远端组件，该远端组件包括耦合器，固定到耦合器的固定螺旋线，其中设置有固定螺旋和耦合器的壳体;以及弹性密封件，其在近端和远端之间固定地固定到耦合器， 能够与耦合器相对于壳体平移。 密封件被定位成密封地接合外壳的内表面。 当联接器平移以使得固定螺旋处于完全伸出位置时，密封件被定位成基本上密封壳体以防止组织向内生长。

    Sensors having protective eluting coating and method therefor
    66.
    发明授权
    Sensors having protective eluting coating and method therefor 有权
    具有保护性洗脱涂层的传感器及其方法

    公开(公告)号：US07225024B2

    公开(公告)日：2007-05-29

    申请号：US10677144

    申请日：2003-09-30

    申请人： Qingsheng Zhu ,  Ronald W. Heil, Jr. ,  Mudit Jain

    发明人： Qingsheng Zhu ,  Ronald W. Heil, Jr. ,  Mudit Jain

    IPC分类号： A61N1/365 ,  A61B5/00

    CPC分类号： A61B5/14546 ,  A61B5/14532 ,  A61N1/0568

    摘要： A cardiac management implantable device that has an intravascular device body, and one or more chemical sensors coupled with the intravascular device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near the one or more chemical sensors, where the drug eluting substance prevents fibrotic growth on the one or more chemical sensors.

    摘要翻译： 一种具有血管内装置体的心脏管理可植入装置，以及与血管内装置本体结合的一个或多个化学传感器。 药物洗脱物质被布置在包括一个或多个化学传感器中的至少一个，直接相邻或接近的位置，其中药物洗脱物质防止在一个或多个化学传感器上的纤维化生长。

    Positive fixation device
    68.
    发明授权
    Positive fixation device 失效
    正固定装置

    公开(公告)号：US5425756A

    公开(公告)日：1995-06-20

    申请号：US174919

    申请日：1993-12-29

    申请人： Ronald W. Heil, Jr. ,  Robert W. Wickham, Jr. ,  Bruce H. Kenknight

    发明人： Ronald W. Heil, Jr. ,  Robert W. Wickham, Jr. ,  Bruce H. Kenknight

    IPC分类号： A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/0573

    摘要： An implantable defibrillation electrode including a conductive distal end portion and a non-conductive proximal end portion is provided with at least a major portion of the length of the distal end portion having a pre-configured shape and being resiliently deformable into a generally straight condition. The distal end portion includes distal and proximal ends and at least one of those ends is hollow and has hook structure shiftably supported therein for movement longitudinally thereof from a retracted position at least substantially contained within the hollow end and an extended position at least substantially fully outwardly projected from the hollow end. Spring structure is provided for yieldingly biasing the hook structure from the extended position toward the retracted position and axial thrust developing structure is slidingly telescoped through the proximal end portion and operatively associated with the hook structure for exerting an axial thrust thereon from the terminal end of the proximal end portion in order to effect shifting of the hook structure from the retracted position to the extended position.

    摘要翻译： 包括导电性末端部和非导电性基端部的可植入除颤电极具有前端部的长度的至少大部分具有预先构造的形状，并且可弹性变形为大致直线的状态。 远端部分包括远端和近端，并且这些端部中的至少一个端部是中空的并且具有可移动地支撑在其中的钩结构，用于使其纵向移动，从至少基本上容纳在中空端部内的缩回位置和至少基本上完全向外的延伸位置 从中空端突出。 提供弹簧结构用于使挂钩结构从延伸位置朝向缩回位置有效地偏置，并且轴向推力显影结构通过近端部分滑动伸缩并与钩结构可操作地相关联，从而从其上端施加轴向推力 近端部分，以便实现钩结构从缩回位置到延伸位置的移动。

    Controlled discharge defibrillation electrode
    69.
    发明授权
    Controlled discharge defibrillation electrode 失效
    控制放电除颤电极

    公开(公告)号：US5063932A

    公开(公告)日：1991-11-12

    申请号：US416421

    申请日：1989-10-03

    申请人： Roger W. Dahl ,  Ronald W. Heil, Jr.

    发明人： Roger W. Dahl ,  Ronald W. Heil, Jr.

    IPC分类号： A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/0587 ,  A61N1/0563

    摘要： A defibrillation electrode for implantation on or about the heart and for connection to a defibrillation system. The electrode comprises a plurality of electrically conductive elements spaced apart and electrically connected together, thus, increasing the number of discharging edges on the electrode. In a first embodiment, the electrode comprises a plurality of concentric conductive rings electrically connected together. In a second embodiment, electrode comprises a plurality of conductive planar elements electrically connected together in a generally puzzle-like configuration. In a third embodiment, the electrode comprises electrically conductive wires wrapped around the length of a cardiac catheter. In a fourth embodiment, electrically conductive wires are concentrically spiralled into a spiral patch configuration. In a fifth specific embodiment, a plurality of electrically isolated active sites are provided on the distal portion of an endocardial catheter. In all of the above embodiments, the electrical discharge of energy from the electrode to the heart surface favors the conductive edges of the electrically conductive and connected components of the electrodes. Therefore, by increasing the number of conductive edges, a more uniform distribution of energy is delivered to the heart. Furthermore, each of the electrode configurations may be constructed without an insulative backing to further increase the efficiency of discharge.

    摘要翻译： 用于植入在心脏上或其周围并用于与除颤系统连接的除颤电极。 电极包括间隔开并电连接在一起的多个导电元件，从而增加电极上的放电边缘的数量。 在第一实施例中，电极包括电连接在一起的多个同心导电环。 在第二实施例中，电极包括多个导电平面元件，其通常以类似益智的结构电连接在一起。 在第三实施例中，电极包括围绕心脏导管的长度缠绕的导电线。 在第四实施例中，导电线同心地螺旋成螺旋形贴片构型。 在第五具体实施方案中，在心内膜导管的远侧部分上设置多个电隔离的活性部位。 在所有上述实施例中，从电极到心脏表面的能量放电有利于电极的导电和连接部件的导电边缘。 因此，通过增加导电边缘的数量，将更均匀的能量分布传递到心脏。 此外，每个电极配置可以构造成没有绝缘背衬，以进一步提高放电效率。

    Low energy defibrillation electrode
    70.
    发明授权
    Low energy defibrillation electrode 失效
    低能除颤电极

    公开(公告)号：US5020544A

    公开(公告)日：1991-06-04

    申请号：US430050

    申请日：1989-11-01

    申请人： Roger W. Dahl ,  Ronald W. Heil, Jr. ,  Graydon E. Beatty ,  Morton M. Mower

    发明人： Roger W. Dahl ,  Ronald W. Heil, Jr. ,  Graydon E. Beatty ,  Morton M. Mower

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587

    摘要： An implantable cardiac electrode for use in defibrillation. The electrode comprises a plurality of layers of porous conductive screens and backed by an insulation layer. When implanted on or about the heart surface, body fluids can flow through the screens thus increasing the effective surface area of contact. Each individual layer of mesh can be microscopically textured to create indentations on the layer for further increasing the surface area of each screen, and thus, the surface area of body fluid contact. Also disclosed is an electrode without an insulative backing facing away from the heart.

    摘要翻译： 用于除颤的植入式心脏电极。 电极包括多层多孔导电屏，并由绝缘层支撑。 当植入心脏表面或其周围时，体液可以流过筛网，从而增加接触的有效表面积。 每个单独的网格层可以被显微纹理化以在该层上产生凹痕，以进一步增加每个筛网的表面积，并因此增加体液接触的表面积。 还公开了一种没有背离心脏的绝缘背衬的电极。