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61.发明授权Method for obtaining strain from radially-tagged magnetic resonance imaging (MRI) 有权从径向标记的磁共振成像（MRI）获得应变的方法公开(公告)号：US08073523B2
公开(公告)日：2011-12-06
申请号：US11810806
申请日：2007-06-06
IPC分类号： A61B5/055
CPC分类号： G01R33/56333
摘要： The present invention relates to a system for obtaining strain corresponding to an object's deformation by radially-tagged magnetic resonance imaging (MRI). The system acquires at least a ring-shaped crown region of Fourier domain (k-space) data for at least two sequential images of a radially-tagged object at different phases of deformation of the radially-tagged object. A first image represents a primary state of the radially-tagged object and a second image represents a secondary state of the radially-tagged object. Additionally, the images include radial tag lines. The first and second images are reconstructed as a reconstructed primary-state image and a reconstructed secondary-state image. The images are reconstructed as weighted by circumferential density of the radial tag lines, such that they are “tag line density-weighted” reconstructed images. Circumferential strain of the radially-tagged object is determined by comparing the two images.
摘要翻译： 本发明涉及通过径向标记的磁共振成像（MRI）获得对应于物体的变形的应变的系统。 该系统在径向标记物体的不同变形阶段获取至少两个具有径向标记物体的连续图像的傅立叶域（k-空间）数据的环形冠部区域。 第一图像表示径向标记对象的主状态，第二图像表示径向标记对象的次状态。 另外，图像包括径向标签线。 第一和第二图像被重建为重建的主状态图像和重建的次状态图像。 通过径向标签线的圆周密度来重建图像，使得它们是“标签线密度加权”重建图像。 通过比较两个图像来确定径向标记物体的周向应变。
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62.发明申请METHOD TO GENERATE MICRO SCALE GAS FILLED LIQUID BUBBLES AS TRACER PARTICLES OR INHALER MIST FOR DRUG DELIVERY 审中-公开生产微量气体填充液体泡沫作为追踪颗粒或吸入剂雾剂用于药物输送的方法公开(公告)号：US20110284648A1
公开(公告)日：2011-11-24
申请号：US13089910
申请日：2011-04-19
申请人： Morteza Gharib , Daegyoum Kim
发明人： Morteza Gharib , Daegyoum Kim
CPC分类号： A61M11/00 , A61M11/007 , A61M2202/0468 , B05B7/0018
摘要： A method and apparatus that enables the production of micron-scale free-standing bubbles made of liquids containing surfactants are provided. The method and apparatus of the invention overcomes the limitations of conventional bubble forming techniques by using a controlled cavitation process in a liquid media.
摘要翻译： 提供了能够生产由含有表面活性剂的液体制成的微米级独立气泡的方法和装置。 本发明的方法和装置通过在液体介质中使用受控的空化工艺来克服常规气泡形成技术的局限性。
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63.发明申请FABRICATION OF ANCHORED CARBON NANOTUBE ARRAY DEVICES FOR INTEGRATED LIGHT COLLECTION AND ENERGY CONVERSION 有权用于集成光收集和能量转换的固定碳纳米管阵列装置的制造公开(公告)号：US20110236619A1
公开(公告)日：2011-09-29
申请号：US13105777
申请日：2011-05-11
CPC分类号： H01L51/444 , B29C70/88 , B29K2105/16 , B29K2105/167 , B29K2995/0018 , B82Y10/00 , B82Y15/00 , B82Y20/00 , B82Y30/00 , C01B31/022 , C01B32/158 , C08J5/005 , H01L51/0048 , H01L51/0049 , H01L51/4253 , Y02E10/549 , Y10S977/742 , Y10S977/753 , Y10T428/23921 , Y10T428/23957 , Y10T428/23979 , Y10T428/24355 , Y10T428/30
摘要： A method of fabricating optical energy collection and conversion devices using carbon nanotubes (CNTs), and a method of anchoring CNT's into thin polymeric layers is disclosed. The basic method comprises an initial act of surrounding a plurality of substantially aligned nanostructures within at least one fluid layer of substantially uniform thickness such that a first end of the plurality of nanostructures protrudes from the fluid layer. Next, the fluid layer is altered to form an anchoring layer, thereby fastening the nanostructures within the primary anchoring layer with the first ends of the nanostructures protruding from a first surface of the primary anchoring layer. Finally, a portion of the anchoring layer is selectively removed such that a second end of the nanostructures is exposed and protrudes from the anchoring layer. The resulting product is an optically absorbent composite material having aligned nanostructures protruding from both sides of an anchoring layer.
摘要翻译： 公开了一种使用碳纳米管（CNT）制造光能收集和转换装置的方法，以及将CNT锚定到薄聚合物层中的方法。 基本方法包括在基本均匀厚度的至少一个流体层内围绕多个基本排列的纳米结构的初始动作，使得多个纳米结构的第一端从流体层突出。 接下来，改变流体层以形成锚定层，从而将纳米结构紧固在主锚定层内，纳米结构的第一端从主锚定层的第一表面突出。 最后，锚定层的一部分被选择性地去除，使得纳米结构的第二端被暴露并从锚定层突出。 所得产品是具有从锚定层的两侧突出的取向的纳米结构的光学吸收复合材料。
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公开(公告)号：US20110111365A1
公开(公告)日：2011-05-12
申请号：US12940847
申请日：2010-11-05
IPC分类号： A61C5/02
摘要： Apparatus and methods for root canal treatments are provided. In some embodiments, an aiming element may be used to position a high-velocity liquid jet near a desired location in the tooth. Embodiments of the aiming element may include an interrupter that deflects or impedes the liquid jet when it is not desirable for the jet to propagate from the aiming element. Embodiments of the aiming element may include an elongated member that permits passage of the liquid jet through a channel. The elongated member may include one or more openings, for example, on sides and/or ends of the member. Some root canal cleaning techniques include one or more applications of the liquid jet followed by application of a disinfectant such as, for example, an aqueous solution of sodium hypochlorite.
摘要翻译： 提供了根管治疗的装置和方法。 在一些实施例中，瞄准元件可用于将高速液体射流定位在牙齿中所需位置附近。 瞄准元件的实施例可以包括当不期望射流从瞄准元件传播时偏转或阻止液体射流的中断器。 瞄准元件的实施例可以包括允许液体射流通过通道的细长构件。 细长构件可以包括例如在构件的侧面和/或端部上的一个或多个开口。 一些根管清洁技术包括液体射流的一个或多个应用，然后施加消毒剂，例如次氯酸钠水溶液。
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65.发明申请METHOD APPLYING HEMODYNAMIC FORCING AND KLF2 TO INITIATE THE GROWTH AND DEVELOPMENT OF CARDIAC VALVES 审中-公开应用血液动力学和KLF2方法来启动心脏瓣膜的生长和发育公开(公告)号：US20110033933A1
公开(公告)日：2011-02-10
申请号：US12837369
申请日：2010-07-15
CPC分类号： A61L27/3625 , A61F2/2415 , A61L27/3834 , A61L27/507 , A61L2430/20 , C12M21/08 , C12M25/14 , C12M29/12 , C12M35/04 , C12N5/0657 , C12N2501/15 , C12N2501/165 , C12N2521/00
摘要： A method for forming a cardiovascular structure in culture is provided. The method includes applying mechanical force to a cell population in culture such that a cardiovascular structure is formed. In some embodiments, the mechanical force is produced in culture medium by a pulsatile liquid flow with a retrograde component. The cell population can include stem cells or differentiated cells, or combinations of both. In particular embodiments, a cardiovascular valve is formed. Scaffolds for the support and growth of the cell population, and bioreactors including the scaffolds, are also provided.
摘要翻译： 提供了一种在培养中形成心血管结构的方法。 该方法包括对培养物中的细胞群体施加机械力，从而形成心血管结构。 在一些实施方案中，通过具有逆行组分的脉动液体流在培养基中产生机械力。 细胞群可包括干细胞或分化细胞，或两者的组合。 在特定实施例中，形成心血管瓣膜。 还提供了用于支持和生长细胞群体的支架，以及包括支架的生物反应器。
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公开(公告)号：US07833016B2
公开(公告)日：2010-11-16
申请号：US11752812
申请日：2007-05-23
申请人： Morteza Gharib , Erik Hars
发明人： Morteza Gharib , Erik Hars
IPC分类号： A61C5/02
CPC分类号： A61C5/04 , A61C5/50 , A61C5/62 , A61K6/0008 , A61K6/0038 , A61K6/0041 , A61L27/04 , A61L27/34 , A61L2430/12 , A61K6/0017 , C08L83/04
摘要： In various embodiments of a method for filling root canal spaces, the root canal spaces are cleaned and irrigated, for example, by any suitable endodontic procedure, and the irrigating liquid is not removed from the canal spaces prior to filling. In some embodiments, a hydrophobic filler material is introduced into the root canal spaces while they are filled with liquid. As the canal spaces are filled, the hydrophobic filler material displaces the liquid and drives it out of the canal spaces, towards the crown of the tooth, where it can be removed. The hydrophobic filler material may comprise magnetically responsive particles having a hydrophobic surface coating that are compacted into the root canal spaces by application of a magnetic force field. In other embodiments, hydrophilic filler material in a flowable phase is introduced into the canal spaces where it partly displaces and partly absorbs the irrigating liquid before solidifying.
摘要翻译： 在用于填充根管空间的方法的各种实施例中，例如通过任何合适的牙髓手术来清洁和灌溉根管空间，并且冲洗液体在填充之前不从运河空间中移除。 在一些实施方案中，将疏水性填料材料引入根管空间，同时填充液体。 随着运河空间的填充，疏水性填充材料使液体移动，并将其从运河空间驱动，朝向牙齿的冠部移动，在那里可以将其移除。 疏水性填料可以包括具有通过施加磁力场而被压实成根管空间的疏水表面涂层的磁响应颗粒。 在其他实施方案中，可流动相中的亲水性填料材料被引入其中部分置换并在凝固之前部分地吸收冲洗液体的运河空间中。
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公开(公告)号：US07715018B2
公开(公告)日：2010-05-11
申请号：US11784304
申请日：2007-04-05
申请人： Morteza Gharib , Joshua Adams
发明人： Morteza Gharib , Joshua Adams
IPC分类号： G01B11/24
CPC分类号： G01S15/8993 , G01N29/06 , G01N2291/106 , G01S7/52026 , G01S7/5205 , G01S15/8977
摘要： The present invention relates to a system for three-dimensional (3-D) acoustic imaging of a scattering structure using information from a two-dimensional (2-D) image. The system uses a characterized sensor array to emit a signal from the sensor array into an object of interest to generate at least one 2-D representation of the object of interest. The 2-D representation comprises a plurality of x and y coordinate pairs and at least one candidate scattering structure. The candidate scattering structure comprises a shape defined by at least one pair of x and y coordinates. The candidate scattering structure shape is restricted to at least one pair of x and y coordinates. The pair of x and y coordinates of the candidate scattering structure shape are then compared with a first coordinate-dependent response function to assign an x, y, and z position of a scattering structure in 3-D space.
摘要翻译： 本发明涉及使用来自二维（2-D）图像的信息的散射结构的三维（3-D）声学成像系统。 该系统使用表征的传感器阵列将来自传感器阵列的信号发射到感兴趣的对象中，以产生感兴趣对象的至少一个2-D表示。 2-D表示包括多个x和y坐标对以及至少一个候选散射结构。 候选散射结构包括由至少一对x和y坐标定义的形状。 候选散射结构形状被限制为至少一对x和y坐标。 然后将候选散射结构形状的一对x和y坐标与第一坐标依赖响应函数进行比较，以在3-D空间中分配散射结构的x，y和z位置。
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公开(公告)号：US07524298B2
公开(公告)日：2009-04-28
申请号：US11137852
申请日：2005-05-24
CPC分类号： A61M5/14276 , A61M27/006
摘要： A shunt system for use in a human body that is formed from a length of tube that is configured as a pump. The length of tube may be configured as a hydroimpedance pomp, whose surfaces are pressed to pump fluid in the specified direction and way. The length of tube that forms the pump may be connected to shunt inlet and outlet parts, and may also include a valve that is adjustable to prevent back draining of fluid.
摘要翻译： 一种用于人体的分流系统，其由构成为泵的管的长度形成。 管的长度可以被配置为一个抗阻抗性，其表面被按压以沿着指定的方向和方式泵送流体。 形成泵的管的长度可以连接到分流入口和出口部分，并且还可以包括可调节的阀，以防止流体反向排出。
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公开(公告)号：US07513863B2
公开(公告)日：2009-04-07
申请号：US10878591
申请日：2004-06-28
IPC分类号： A61N1/362
CPC分类号： A61M1/101 , A61M1/10 , A61M1/1005 , A61M1/1008 , A61M1/1034 , A61M1/107 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/125 , A61M1/3621 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M25/0026 , A61M25/003 , A61M25/007 , A61M2230/04
摘要： An extracardiac pumping system and method for using it supplement the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart. A battery powered pump may be implanted subcutaneously and attached to an inflow conduit fluidly coupled to a patient's femoral artery via a subcutaneous anastomosis connection. The pump draws blood from the inflow conduit and discharges it through an outflow conduit fluidly coupled to a second peripheral artery via another subcutaneous anastomosis connection. The battery may be charged extracorporeally and the pump may be operated in either a continuous or pulsatile fashion in synchronization with the patient's heart. The conduits can be housed in a multi-lumen catheter and a reservoir may be provided which fluidly communicates with the inflow conduits. An additional feature may keep blood traveling extracorporeally within the system at or near body temperature. The system is capable of adjusting outflow from the pump to optimize the mixing of red blood cells in the aorta and thereby enhance oxygen delivery to tissues by minimizing blood cell concentration in the center of the aorta.
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70.发明申请Aperture system with spatially-biased aperture shapes and positions (SBPSP) for static and dynamic 3-D defocusing-based imaging 审中-公开具有空间偏置孔径形状和位置（SBPSP）的孔径系统，用于静态和动态3-D散焦成像公开(公告)号：US20080278572A1
公开(公告)日：2008-11-13
申请号：US12150239
申请日：2008-04-23
申请人： Morteza Gharib , Emilio Graff , Francisco Pereira
发明人： Morteza Gharib , Emilio Graff , Francisco Pereira
IPC分类号： H04N13/00
CPC分类号： H04N13/254 , G01B11/2509 , G02B5/005 , G02B2207/129 , G03B15/12 , G03B35/02 , G06T7/50 , H04N13/204 , H04N13/207
摘要： A device and method for three-dimensional (3-D) imaging using a defocusing technique is disclosed. The device comprises a lens, a plurality of spatially-biased apertures obstructing the lens, a sensor operable for capturing light transmitted from an object through the lens and the plurality of spatially-biased apertures, and a processor communicatively connected with the sensor for processing the sensor information and producing a 3-D image of the object. The spatially-biased apertures may differ in shape, size, and/or distance from the optical axis.
摘要翻译： 公开了一种使用散焦技术进行三维（3-D）成像的装置和方法。 该装置包括透镜，多个空间偏置的孔，阻挡透镜，可操作用于捕获从物体透过透镜和多个空间偏置孔的光的传感器，以及与传感器通信连接的处理器 传感器信息并产生物体的三维图像。 空间偏置的孔可以在与光轴的形状，尺寸和/或距离上不同。
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