INSULIN RELATED TRANSCRIPTION FACTOR AND USES THEREOF
    61.
    发明申请
    INSULIN RELATED TRANSCRIPTION FACTOR AND USES THEREOF 失效
    胰岛素相关转录因子及其用途

    公开(公告)号:US20080081337A1

    公开(公告)日:2008-04-03

    申请号:US11838068

    申请日:2007-08-13

    申请人: Arun Sharma

    发明人: Arun Sharma

    CPC分类号: C07K14/705

    摘要: The invention provides isolated mMafA polypeptides, nucleic acids, vectors and host cells containing them, which encode a novel insulin related transcription factor. Diagnostic methods, methods of selecting and differentiating insulin-producing cells, and methods of treatment utilizing compositions of the invention are also provided.

    摘要翻译: 本发明提供了分离的mMafA多肽,核酸,载体和含有它们的宿主细胞,其编码新的胰岛素相关转录因子。 还提供诊断方法,选择和区分胰岛素产生细胞的方法,以及利用本发明组合物的治疗方法。

    Self-monitoring and self-healing of frequency specific position errors in a data storage device
    64.
    发明授权
    Self-monitoring and self-healing of frequency specific position errors in a data storage device 失效
    数据存储设备中频率特定位置误差的自我监测和自我修复

    公开(公告)号:US06937422B2

    公开(公告)日:2005-08-30

    申请号:US10289603

    申请日:2002-11-07

    CPC分类号: G11B5/596 G11B19/04

    摘要: An apparatus and method of controlling an actuator of a data storage device detect and/or correct narrowband mechanical excitations such as due to spindle bearing defects through sensing and/or rejecting disturbance frequencies associated with such narrowband mechanical excitations in an actuator control signal generated by a data storage device controller. A narrowband filter may be used to reject, from an actuator control signal generated by a data storage device controller, a disturbance frequency associated with a spindle bearing defect in a data storage device, and disposed in proximity to a zero crossover frequency associated with the data storage device controller. In addition, a peak filter disposed in a control loop of a data storage device controller may be configured to detect a spindle bearing defect in a data storage device by detecting an amplitude of a control signal in the control loop in proximity to a disturbance frequency associated with the spindle bearing defect.

    摘要翻译: 控制数据存储设备的致动器的装置和方法通过检测和/或排除与由这样的窄带机械激励相关联的干扰频率来检测和/或校正窄带机械激励,例如由于主轴承载缺陷而导致的致动器控制信号产生的干扰频率 数据存储设备控制器。 窄带滤波器可以用于从数据存储设备控制器产生的致动器控制信号中拒绝与数据存储设备中的主轴承载缺陷相关联的干扰频率,并且设置在与数据相关联的零交叉频率附近 存储设备控制器 此外,布置在数据存储装置控制器的控制环路中的峰值滤波器可以被配置为通过检测控制回路中与干扰频率相关联的控制信号的幅度来检测数据存储装置中的主轴承载缺陷 主轴轴承缺陷。

    Human hematopoietic growth regulatory gene and uses
    65.
    发明授权
    Human hematopoietic growth regulatory gene and uses 失效
    人造血生长调节基因及用途

    公开(公告)号:US06900017B2

    公开(公告)日:2005-05-31

    申请号:US10043774

    申请日:2002-01-10

    摘要: The present invention relates to novel human hiwi protein and genes that encode such proteins. The invention is directed toward the isolation and characterization of human hiwi proteins. The invention specifically provides isolated complementary DNA copies of mRNA corresponding a human hiwi gene. Also provided are recombinant expression constructs capable of expressing the human hiwi gene of the invention in cultures of transformed prokaryotic and eukaryotic cells, as well as such cultures of transformed cells that synthesize the human hiwi proteins encoded therein. The invention also provides methods for isolating human hematopoietic stem cells.

    摘要翻译: 本发明涉及编码这种蛋白质的新型人类hiwi蛋白质和基因。 本发明涉及人类hiwi蛋白的分离和表征。 本发明特别提供了与人hiwi基因相对应的mRNA的分离的互补DNA拷贝。 还提供了能够在转化的原核和真核细胞的培养物中表达本发明的人hiwi基因以及合成其中编码的人hiwi蛋白的转化细胞的这种培养物的重组表达构建体。 本发明还提供了分离人类造血干细胞的方法。

    Disk-flutter servo control in rotating storage system with optimum disk thickness
    66.
    发明授权
    Disk-flutter servo control in rotating storage system with optimum disk thickness 有权
    旋转存储系统中的磁盘颤动伺服控制,磁盘厚度最佳

    公开(公告)号:US06339512B1

    公开(公告)日:2002-01-15

    申请号:US09276211

    申请日:1999-03-25

    IPC分类号: G11B5596

    摘要: A hard disk has a servo loop and a rotating storage medium. The rotating storage medium has one or more significant flutter modes at frequencies below a zero cross frequency of a rejection transfer function of the servo loop. The effect of the forgoing is to allow the servo loop to better track a rotating medium that is subject to significant flutter. Peak filters with frequency bands that substantially overlap frequency bands of the significant flutter modes can also be added to the servo loop to further improve tracking. Multiple narrow band filters with frequency bands overlap can be used to cover the spectrum of a single flutter mode. Two lag-lead filters, the frequency responses of which overlap can be used to cover two adjacent significant flutter modes. At frequencies intermediate to the two adjacent flutter, modes, the lead caused by one filter, will be cancelled by the lag caused by the second.

    摘要翻译: 硬盘具有伺服回路和旋转存储介质。 旋转存储介质在低于伺服环路的拒绝传递函数的零交叉频率的频率下具有一个或多个显着颤振模式。 上述的效果是允许伺服回路更好地跟踪受到显着颤动的旋转介质。 具有基本上与重要抖动模式的频带重叠的频带的峰值滤波器也可以被添加到伺服环路中以进一步改善跟踪。 具有频带重叠的多个窄带滤波器可以用于覆盖单个颤振模式的频谱。 两个滞后引线滤波器,其重叠的频率响应可用于覆盖两个相邻的显着颤振模式。 在两个相邻颤振之间的频率中,模式,由一个滤波器引起的引线将被第二个引起的滞后所抵消。

    Repeatable runout free servo architecture in direct access storage device
    67.
    发明授权
    Repeatable runout free servo architecture in direct access storage device 失效
    可重复跳出自由伺服架构在直接存取存储设备

    公开(公告)号:US6097565A

    公开(公告)日:2000-08-01

    申请号:US594572

    申请日:1996-01-31

    IPC分类号: G11B21/10 G11B5/596

    CPC分类号: G11B5/59627

    摘要: In a direct access storage device including a rotating disk, a head positioned for interaction with said disk, an actuator for carrying said head and a servo system for operating said actuator so as to follow a substantially circular track on said disk by responding to a position error signal, a method for reducing response of the servo system to radial runout of the circular tracks, comprising the steps of obtaining radial runout data; filtering the data; storing the filtered data; subtracting the filtered data from the position error signal to obtain a corrected position error signal; and using the corrected position error signal to control the servo system. A direct access storage device in accordance with the invention includes means for obtaining radial runout data; means for filtering the data; means for storing the filtered data; means for subtracting the filtered data from the position error signal to obtain a corrected position error signal; and means for controlling the servo system using the corrected position error signal.

    摘要翻译: 在包括旋转盘的直接存取存储装置中,用于与所述盘相互作用的头部,用于承载所述头部的致动器和用于操作所述致动器的伺服系统,以便通过响应于位置 误差信号,用于减小伺服系统对圆形轨道的径向跳动的响应的方法,包括以下步骤:获得径向跳动数据; 过滤数据; 存储经过滤的数据; 从位置误差信号中减去滤波后的数据,得到校正后的位置误差信号; 并使用校正的位置误差信号来控制伺服系统。 根据本发明的直接存取存储装置包括用于获得径向跳动数据的装置; 用于过滤数据的手段; 用于存储经过滤数据的装置; 用于从所述位置误差信号中减去所述滤波数据以获得校正的位置误差信号的装置; 以及用于使用校正的位置误差信号来控制伺服系统的装置。

    Magnetic disk unit and method for controlling the same
    68.
    发明授权
    Magnetic disk unit and method for controlling the same 失效
    磁盘单元及其控制方法

    公开(公告)号:US5579186A

    公开(公告)日:1996-11-26

    申请号:US416587

    申请日:1995-04-03

    摘要: In an idle state, servo information from all sectors is not used, but the servo information from every other sector or from every three or more sectors is used so that head positioning can be performed with only a minimum amount of servo information. The power to the electric circuitry of a write or read system and a servo system, which is not needed in the idle state, is interrupted, from the arrival of the selected servo information to the arrival of the next selected servo information, by a power control signal generated in accordance with the timing of the sectors. The power consumption can be reduced by the amount corresponding to turning off the circuitry not needed, plus the amount needed for computing for position control.

    摘要翻译: 在空闲状态下,不使用来自所有扇区的伺服信息,而是使用来自每个其他扇区或每三个或更多个扇区的伺服信息,以便只能以最小量的伺服信息执行磁头定位。 在空闲状态下不需要的写入或读取系统和伺服系统的电路的电力从所选择的伺服信息的到达到下一个所选择的伺服信息的到达被中断, 控制信号根据扇区的时序产生。 功耗可以减少对应于关闭不需要的电路的数量,加上用于位置控制的计算所需的量。

    Inter-sample switching of servo control in direct access storage devices
    69.
    发明授权
    Inter-sample switching of servo control in direct access storage devices 失效
    直接存取存储设备中伺服控制的采样间切换

    公开(公告)号:US5381282A

    公开(公告)日:1995-01-10

    申请号:US779438

    申请日:1991-10-18

    IPC分类号: G11B21/08 G11B5/596

    CPC分类号: G11B5/596

    摘要: A direct access storage device and a method of operation thereof where the output of the circuit which controls energy to the position actuator for the head may be changed at times between receipt of sequential position error signals from the medium. Instead of waiting for the next position error signal, a computation is done based on at least the current position and the desired position of the head as to when the head velocity will be equal to a desired velocity. The optimum time to switch is estimated, the energy required to achieve a predetermined velocity and a predetermined offset with respect to the desired position are computed, and operation is conducted accordingly. The amount of energy may again be changed at a time subsequent to the estimated time. The predetermined velocity and the predetermined offset may be zero or may have values other than zero in accordance with the requirements of the track following controller.

    摘要翻译: 一种直接存取存储装置及其操作方法,其中可以在接收到来自介质的连续位置误差信号之间的时候改变控制头部位置致动器的能量的电路的输出。 代替等待下一个位置误差信号,至少基于头部的当前位置和期望位置来计算关于头部速度将等于期望速度的时间。 估计最佳切换时间,计算实现预定速度所需的能量和相对于期望位置的预定偏移量,并相应地进行操作。 在估计时间之后的时间,能量的量再次可以改变。 预定速度和预定偏移可以为零,或者可以根据跟踪跟踪控制器的要求具有除零之外的值。

    LINKING OPEN OFFERS AND NEGOTIATION HISTORY
    70.
    发明申请
    LINKING OPEN OFFERS AND NEGOTIATION HISTORY 审中-公开
    连接开放和谈判历史

    公开(公告)号:US20160180422A1

    公开(公告)日:2016-06-23

    申请号:US14582044

    申请日:2014-12-23

    申请人: Arun Sharma

    发明人: Arun Sharma

    IPC分类号: G06Q30/06

    CPC分类号: G06Q30/0613 G06Q30/0611

    摘要: Systems and methods are presented for linking open offers and negotiation history of a terminated transaction to a newly listed transaction. In some embodiments, the system presents a first item listing including at least a portion of a first set of data indicative of a product. The system receives interaction data indicative of a user interacting with the first item listing and associates the interaction data with the first item listing. The interaction data includes an offer of a user for purchase of a product. The system terminates the first item listing based on a predetermined time period and generates a second item listing including the portion of the first set of data included in the first item listing and the interaction data associated with the first item listing.

    摘要翻译: 系统和方法被提供用于将终止的交易的公开报价和谈判历史链接到新上市的交易。 在一些实施例中,系统呈现包括指示产品的第一组数据的至少一部分的第一项目列表。 系统接收指示用户与第一项目列表交互并且将交互数据与第一项目列表相关联的交互数据。 交互数据包括用户购买产品的提议。 系统基于预定时间段终止第一项目列表,并且生成包括第一项目列表中包括的第一组数据的部分和与第一项目列表相关联的交互数据的第二项目列表。