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70 条记录 (耗时 0.024 秒)

    Method for providing a sterility seal in a medicinal storage bottle
    62.
    发明授权
    Method for providing a sterility seal in a medicinal storage bottle 失效
    在药用储藏瓶中提供无菌密封的方法

    公开(公告)号：US5613291A

    公开(公告)日：1997-03-25

    申请号：US377885

    申请日：1995-01-25

    申请人： Donald D. Solomon ,  Jean-Claude Thibault

    发明人： Donald D. Solomon ,  Jean-Claude Thibault

    IPC分类号： B65B7/28 ,  A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  B65D41/02 ,  B65D53/06 ,  B23P25/00

    CPC分类号： A61J1/2089 ,  A61J1/1412 ,  A61J1/18 ,  A61J1/1468 ,  A61J1/201 ,  Y10S604/905 ,  Y10T29/49885 ,  Y10T29/49982

    摘要： A bottle having a sterility seal and a method for producing same are disclosed. The bottle, which can be configured to retain a medicament in powder or tablet form, features a protective cap configured to engage a transfer assembly associated with the bottle. The cap includes one or more raised ridges on an interior surface engageable with a portion of the transfer assembly. A band or layer configuration of a sealing material such as silicone is applied to the transfer assembly prior to insertion of the cap thereover. As the cap comes into surface contact with the sealing material, the ridges cause the material to "roll up" into a toroidal O-ring configuration, thereby forming a seal between the cap and the bottle adapted to the dimensional variations of those components. The seal, which is resilient, is able to withstand harsh handling treatment and pressure or temperature variations without separation from the cap or bottle, thereby providing a hermetic seal isolating the transfer assembly and, hence, the medicament from the outside environment.

    摘要翻译： 公开了一种具有无菌密封的瓶子及其制造方法。 可以构造成保持粉末或片剂形式的药物的瓶具有构造成接合与瓶相关联的转运组件的保护帽。 所述盖包括在内表面上与所述转移组件的一部分可接合的一个或多个凸脊。 在其上插入盖之前，将诸如硅树脂的密封材料的带或层构造施加到转移组件。 当盖与密封材料进行表面接触时，脊使材料“卷起”成环形O形环构型，从而在适于这些部件的尺寸变化的帽和瓶之间形成密封。 具有弹性的密封件能够承受恶劣的处理处理和压力或温度变化，而不会与盖或瓶分离，从而提供将转印组件以及因此从外部环境分离的气密密封。

    Method of making an article having a hemocompatible surface
    66.
    发明授权
    Method of making an article having a hemocompatible surface 失效
    制备具有血液相容性表面的制品的方法

    公开(公告)号：US5059269A

    公开(公告)日：1991-10-22

    申请号：US491020

    申请日：1990-03-09

    申请人： Can B. Hu ,  Donald D. Solomon ,  Stanley C. Wells

    发明人： Can B. Hu ,  Donald D. Solomon ,  Stanley C. Wells

    IPC分类号： A61L33/06 ,  C08G18/61

    CPC分类号： C08G18/61 ,  A61L33/068

    摘要： An article has a blood-contacting hemocompatible surface layer of a urethane-siloxane copolymer on a thermoplastic polymeric base material. The copolymer has siloxane segments prepared from hydroxyalkyl terminated polysiloxane glycols. The article is prepared by coextrusion of the base material and the copolymer.

    摘要翻译： 制品在热塑性聚合物基材上具有聚氨酯 - 硅氧烷共聚物的与血液接触的血液相容性表面层。 该共聚物具有由羟烷基封端的聚硅氧烷二醇制备的硅氧烷链段。 该制品通过共挤出基材和共聚物制备。

    Catheter obturator with automatic feed and control
    68.
    发明授权
    Catheter obturator with automatic feed and control 失效
    导管闭塞器具有自动进料和控制

    公开(公告)号：US4976697A

    公开(公告)日：1990-12-11

    申请号：US427422

    申请日：1989-10-26

    申请人： Anthony J. Walder ,  Donald D. Solomon ,  Richard W. Beck ,  James M. Lambert ,  Timothy Ignatius ,  Mark Crawford

    发明人： Anthony J. Walder ,  Donald D. Solomon ,  Richard W. Beck ,  James M. Lambert ,  Timothy Ignatius ,  Mark Crawford

    IPC分类号： A61M25/00 ,  A61M25/01

    CPC分类号： A61M25/0017 ,  A61M25/0113

    摘要： An obturator is provided which allows for placing and withdrawing of a single catheter obturator over an extended period of time so as to allow speed intervals of use, and non-use of a catheter while in place in the patient's skin, while at the same time doing away with cumbersome, costly and time consuming administration and maintenance of saline and heparin locks. The device feeds the obturator in place for occluding the catheter lumen, when no fluids are being administered to the patient, and then may be retracted to a position allowing fluid feed through a supply tube connection to the catheter. The device includes a coating on the obturator rod which swells in contact with aqueous fluids to seal completely the catheter lumen which coating includes heparin to prevent clotting. Moreover, the entire internal functioning arrangement remains sterile during the entire period of use, thus avoiding infection.

    摘要翻译： 提供了一种闭孔器，其允许在延长的时间段内放置和取出单个导管闭塞器，以允许使用速度间隔，并且在同时在患者皮肤中就位时不使用导管 消除麻醉，昂贵和耗时的盐水和肝素锁的管理和维护。 当没有向患者施用流体时，该装置将闭塞器馈送到适当位置以封闭导管腔，然后可以缩回至允许流体通过与导管连接的供应管的位置。 该装置包括在封闭杆上的涂层，其与水性流体接触膨胀以完全密封导管腔，该涂层包括肝素以防止凝血。 此外，整个内部功能安排在整个使用期间保持不育，从而避免感染。