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70 条记录 (耗时 0.021 秒)

    Anti-infective and antithrombogenic medical articles and method for their preparation
    3.
    发明授权
    Anti-infective and antithrombogenic medical articles and method for their preparation 失效
    抗感染和抗血栓形成的医疗用品及其制备方法

    公开(公告)号：US5013306A

    公开(公告)日：1991-05-07

    申请号：US497780

    申请日：1990-03-21

    申请人： Donald D. Solomon ,  M. Parke Byron

    发明人： Donald D. Solomon ,  M. Parke Byron

    IPC分类号： A61L27/34 ,  A61L27/54 ,  A61L29/06 ,  A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16

    CPC分类号： A61L29/06 ,  A61M2025/0056

    摘要： An anti-infective medical article has chlorhexidine bulk distributed throughout a polyurethane base layer and may have a coating layer on the base layer. The coating layer may be chlorhexidine permeated into the surface or it may be an antibiotic, antithrombogenic agent or a polymeric surface layer laminated onto the base layer. The invention includes a method for preparing the article wherein a homogeneous melt of polymer and chlorhexidine is prepared by twin screw compounding and the melt is extruded to give a medical article having bulk distributed chlorhexidine.

    摘要翻译： 抗感染性医疗用品具有遍及整个聚氨酯基层的氯己定，并且可以在基层上具有涂层。 涂层可以是氯己定渗透到表面中，或者它可以是层压到基底层上的抗生素，抗血栓形成剂或聚合物表面层。 本发明包括一种制备该制品的方法，其中通过双螺杆混合制备聚合物和氯己定的均匀熔体，并将该熔体挤出以得到具有体积分布的氯己定的医用制品。

    Anti-infective and antithrombogenic medical articles and method for their preparation
    4.
    发明授权
    Anti-infective and antithrombogenic medical articles and method for their preparation 失效
    抗感染和抗血栓形成的医疗用品及其制备方法

    公开(公告)号：US4999210A

    公开(公告)日：1991-03-12

    申请号：US449382

    申请日：1989-12-07

    申请人： Donald D. Solomon ,  M. Parke Byron

    发明人： Donald D. Solomon ,  M. Parke Byron

    IPC分类号： A61L27/34 ,  A61L27/54 ,  A61L29/06 ,  A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16

    CPC分类号： A61L29/16 ,  A61L29/06 ,  A61L29/085 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/406 ,  A61L2300/42 ,  A61L2300/608 ,  A61M2025/0056 ,  Y10S514/822 ,  Y10S524/916

    摘要： An anti-infective medical article has chlorhexidine bulk distributed throughout a polyurethane base layer and may have a coating layer on the base layer. The coating layer may be chlorhexidine, an antibiotic, or an antithrombogenic agent permeated into the surface or it may be a polymeric surface layer having bulk distributed chlorhexidine laminated onto the base layer. The invention includes a method for preparing the article wherein a homogeneous melt of polymer and chlorhexidine is prepared by twin screw compounding and the melt is extruded to give a medical article having bulk distributed chlorhexidine. The article may then be laminated by dipping into a solution of chlorhexidine and a substantially hydrophilic polymer in a solvent.

    摘要翻译： 抗感染性医疗用品具有遍及整个聚氨酯基层的氯己定，并且可以在基层上具有涂层。 涂层可以是氯己定，抗生素或渗透到表面中的抗血栓形成剂，或者它可以是层叠在基底层上的体积分散的氯己定的聚合物表面层。 本发明包括一种制备该制品的方法，其中通过双螺杆混合制备聚合物和氯己定的均匀熔体，并将该熔体挤出以得到具有体积分布的氯己定的医用制品。 然后可以通过在溶剂中浸入氯己定和基本亲水性聚合物的溶液中来层压该制品。

    Needle assembly having an elongate blunting device which allows for venting of air
    9.
    发明授权
    Needle assembly having an elongate blunting device which allows for venting of air 失效
    针组件具有允许排出空气的细长钝化装置

    公开(公告)号：US06328717B1

    公开(公告)日：2001-12-11

    申请号：US09453983

    申请日：1999-12-02

    申请人： Donald D. Solomon ,  Michael L. Miller

    发明人： Donald D. Solomon ,  Michael L. Miller

    IPC分类号： A61M532

    CPC分类号： A61M25/0643 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150641 ,  A61B5/1535 ,  A61M25/065 ,  A61M25/0693 ,  A61M2005/3212

    摘要： The invention generally relates to a needle assembly of the kind having a needle, an elongate blunting device, a shifting member, and a flash chamber. The needle is of the kind that has a needle proximal end, a sharp needle distal end and a needle cannula extending therethrough. The elongate blunting device is at least partially located within the needle cannula. The elongate blunting device is of the kind that has a blunting device proximal end, a blunting device distal end, and a blunting device blood flow passage therethrough through which blood can flow from the blunting device distal end to the blunting device proximal end. The shifting member can be actuated to move relative to the needle and, upon movement relative to the needle, causes movement to the elongate blunting device from a retracted position wherein the blunting device distal end is retracted into the needle cannula so that the sharp needle distal end can penetrate the body, to an extended position wherein the blunting device distal end extends out of the needle cannula so as to prevent the sharp needle distal end from penetrating the body.

    摘要翻译： 本发明一般涉及一种具有针头，细长钝化装置，移动构件和闪光室的针组件。 针是具有针近端，尖针头端和延伸穿过其中的针插管的针。 细长钝化装置至少部分地位于针插管内。 细长钝化装置是具有钝器件近端，钝器装置远端以及穿过其的平坦化装置血流通道的类型，血液可以通过该血流通道从平坦化装置远端流到平稳装置近端。 移动构件可以被致动以相对于针移动，并且在相对于针移动时使其从缩回位置移动到细长的钝化装置，其中平坦化装置远端缩回到针插管中，使得尖锐的针远端 末端可以穿透身体到达延伸位置，其中钝化装置远端延伸出针管，以防止尖锐的针头远端穿透身体。