公开(公告)号：US07712806B2

公开(公告)日：2010-05-11

申请号：US11052599

申请日：2005-02-07

申请人： Hideki Adachi

发明人： Hideki Adachi

IPC分类号： B25B11/00

CPC分类号： B32B38/18 ,  B32B38/164 ,  B32B2037/243 ,  B32B2038/1891 ,  B32B2457/14 ,  B32B2457/20 ,  H01L21/6715 ,  H01L21/67167 ,  H01L21/6719 ,  H01L21/67207 ,  H01L21/67248 ,  H01L21/67742 ,  H01L21/68707 ,  Y10S414/141 ,  Y10T156/17 ,  Y10T156/1705 ,  Y10T156/1744

摘要： A center robot is fixed approximately in a central portion of a process part. A coating unit, a drying unit, a transfer unit, a peeling unit, a film supplying unit and a reversing unit are arranged around the center robot. The center robot comprises a hand-for-substrate and a hand-for-film which are allowed to directly access the respective units. Within a process part, the center robot transports a sheet film and/or a substrate between the coating unit, the drying unit, the transfer unit and the film supplying unit, and a thin film is formed on the substrate using the sheet film.

摘要翻译： 中心机器人大约固定在处理部件的中心部分。 中心机器人周围布置有涂布单元，干燥单元，转印单元，剥离单元，胶片供给单元和反转单元。 中心机器人包括被允许直接进入各个单元的手动基板和手工胶片。 在处理部分中，中心机器人在涂布单元，干燥单元，转印单元和膜供应单元之间传送片状薄膜和/或基底，并且使用薄膜在基板上形成薄膜。

公开(公告)号：US07494647B2

公开(公告)日：2009-02-24

申请号：US10462062

申请日：2003-06-16

申请人： Koh Sato ,  Hideki Adachi ,  Naohiro Yabuta

发明人： Koh Sato ,  Hideki Adachi ,  Naohiro Yabuta

IPC分类号： A61K39/395

CPC分类号： C07K16/36 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2319/00

摘要： A humanized antibody against tissue factor (TF), comprising:A: a humanized H chain comprising (1) a H chain V region comprising the H chain CDRs of a mouse monoclonal antibody against TF and the H chain FRs of a human antibody, and (2) the H chain C region of a human antibody; andB: a humanized L chain comprising (1) an L chain V region comprising the L chain CDRs of a mouse monoclonal antibody against TF and the L chain FRs of a human antibody, and (2) the L chain C region of a human antibody.After generating a humanized V region by grafting the CDRs of a mouse monoclonal antibody onto a human antibody, a humanized antibody having a higher activity is searched by replacing the FR of the above region with the corresponding FR of the human antibody having a high homology.

摘要翻译： 一种抗组织因子（TF）的人源化抗体，包括：A：人源化H链，其包含（1）H链V区，其包含针对TF的小鼠单克隆抗体的H链CDR和人抗体的H链FR，以及 （2）人抗体的H链C区; 和B：人源化L链，其包含（1）包含针对TF的小鼠单克隆抗体的L链CDR和人抗体的L链FR的L链V区，和（2）人的L链C区 抗体。 通过将小鼠单克隆抗体的CDR移植到人抗体上产生人源化V区后，通过用具有高同源性的人抗体的相应FR代替上述区域的FR来搜索具有较高活性的人源化抗体。

公开(公告)号：US20080273226A1

公开(公告)日：2008-11-06

申请号：US12111343

申请日：2008-04-29

申请人： Hideki Adachi ,  Koichi Homma ,  Hiroshi Yamaguchi ,  Joji Oki ,  Naohiro Yoshikawa ,  Hideyuki Fujiwara ,  Akira Negishi ,  Shuji Someya

发明人： Hideki Adachi ,  Koichi Homma ,  Hiroshi Yamaguchi ,  Joji Oki ,  Naohiro Yoshikawa ,  Hideyuki Fujiwara ,  Akira Negishi ,  Shuji Someya

IPC分类号： G06K15/02

CPC分类号： G06F3/1204 ,  G06F3/1208 ,  G06F3/125 ,  G06F3/1257 ,  G06F3/1285

摘要： A layout apparatus lays out a document by referencing personal information registered on a per user basis. Even if no particular print setting is input for a print job by a user, excellent prints customized for each user are thus provided.

摘要翻译： 布局装置通过参考在每个用户基础上注册的个人信息来布置文档。 即使用户没有为打印作业输入特定的打印设置，因此提供了为每个用户定制的优秀打印。

公开(公告)号：US06743994B2

公开(公告)日：2004-06-01

申请号：US10606781

申请日：2003-06-27

申请人： Hideki Adachi

发明人： Hideki Adachi

IPC分类号： H01H110

CPC分类号： H01H13/702 ,  H01H2215/002 ,  H01H2215/008 ,  H01H2221/042 ,  H01H2221/05

摘要： A circuitry is provided with a first switching contact. A first spacer is laminated on the circuitry so as to provide a first space above the first switching contact. A first, elastic sheet member is laminated on the first spacer and provided with a second switching contact opposing to the first switching contact in the first space. The first sheet member is operable to deform while using the first space to bring the second switching contact into an electrical contact with the first switching contact. A second spacer is laminated on the first sheet member so as to provide a second space above a first part of the first sheet member. A second sheet member is laminated on the second spacer, the second sheet member being operable to deform while using the second space to thereby deform the first part of the first sheet member. An elastic member is interposed between the first sheet member and the second sheet member at the second space. The elastic member has an elastic deformability which is higher than an elastic deformability of the first sheet member.

摘要翻译： 电路设置有第一开关触点。 第一间隔件层叠在电路上，以便在第一开关触点之上提供第一空间。 第一弹性片构件层叠在第一间隔件上，并且在第一空间中设置有与第一开关触点相对的第二开关触点。 第一片状构件可操作以在使用第一空间的同时使第二开关触点与第一开关触点电接触而变形。 第二间隔件层叠在第一片构件上，以在第一片构件的第一部分上方提供第二空间。 第二片材层压在第二间隔件上，第二片构件可操作以在使用第二空间的同时变形，从而使第一片构件的第一部分变形。 在第二空间处，弹性构件插入在第一片构件和第二片构件之间。 弹性构件具有比第一片构件的弹性变形性高的弹性变形性。

公开(公告)号：US06717320B2

公开(公告)日：2004-04-06

申请号：US10292437

申请日：2002-11-13

申请人： Hideki Adachi ,  Kazuto Nakamura

发明人： Hideki Adachi ,  Kazuto Nakamura

IPC分类号： H01R3900

CPC分类号： B60R16/027 ,  H01R39/10 ,  H01R39/64

摘要： The slip ring device (10) includes stationary and rotary members (11, 20) rotatable to each other. The slip ring device includes a sliding contact system for electrically interconnecting the stationary and rotary members. The sliding contact system includes slip rings (30, 31) with sliding faces (34a, 35a) mounted to one of the stationary and rotary members. The slip rings are separated from each other, with the sliding faces facing each other. The sliding contact system includes sliding contact members (17, 18) mounted to the other of the stationary and rotary members. Each of the sliding contact members slidably contact with each of the sliding faces.

摘要翻译： 滑环装置（10）包括彼此可旋转的固定和旋转构件（11,20）。 滑环装置包括用于将固定和旋转构件电连接的滑动接触系统。 滑动接触系统包括滑动环（30,31），其具有安装到固定和旋转构件之一的滑动面（34a，35a）。 滑环彼此分离，滑动面相互面对。 滑动接触系统包括安装到固定和旋转构件中的另一个的滑动接触构件（17,18）。 每个滑动接触构件与每个滑动面滑动接触。

公开(公告)号：US06677436B1

公开(公告)日：2004-01-13

申请号：US09647468

申请日：2000-09-29

申请人： Koh Sato ,  Hideki Adachi ,  Naohiro Yabuta

发明人： Koh Sato ,  Hideki Adachi ,  Naohiro Yabuta

IPC分类号： C12P2108

CPC分类号： C07K16/36 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2319/00

摘要： The present invention relates to a human/mouse chimeric antibody that includes the variable region of a mouse monoclonal antibody against human tissue factor (TF) and the constant region of a human antibody. The humanized antibody contains light and heavy chain complementarity determining regions of a mouse monoclonal antibody against human TF which have been grafted onto a human antibody. The present invention also provides a therapeutic agent for disseminated intravascular coagulation (DIC) syndrome, which includes a humanized antibody against human TF as an active ingredient.

摘要翻译： 本发明涉及包含针对人组织因子（TF）的小鼠单克隆抗体和人抗体恒定区的可变区的人/小鼠嵌合抗体。 人源化抗体含有已经接枝到人抗体上的针对人TF的小鼠单克隆抗体的轻链和重链互补决定区。 本发明还提供了用于弥散性血管内凝血（DIC）综合征的治疗剂，其包括针对人TF的人源化抗体作为活性成分。

公开(公告)号：US06669808B2

公开(公告)日：2003-12-30

申请号：US10102391

申请日：2002-03-18

申请人： Hideki Adachi ,  Katsuhiko Miya ,  Akira Izumi ,  Itsuki Kajino

发明人： Hideki Adachi ,  Katsuhiko Miya ,  Akira Izumi ,  Itsuki Kajino

IPC分类号： B08B504

CPC分类号： H01L21/68728 ,  G03F7/3021 ,  H01L21/6715 ,  H01L21/6838

摘要： A support member of a rotary base member engages with a substrate for preventing the substrate from horizontal movement and rotation with respect to the rotary base member while allowing vertical movement of the substrate, and a proximity suction plate is provided above the rotary base member so that the lower surface thereof is formed on a plane on the rotary base member parallel to the substrate for downwardly and outwardly injecting gas toward the overall upper surface of the substrate and sucking the substrate in a proximity state by Bernoulli effect. It is possible to provide an apparatus capable of reliably preventing mist of a processing solution or the processing solution from reaching the upper surface of the substrate when rotating the substrate and supplying the processing solution to the lower surface for processing the substrate.

公开(公告)号：US06323017B1

公开(公告)日：2001-11-27

申请号：US09196222

申请日：1998-11-20

申请人： Hideki Adachi ,  Masafumi Tsujimoto ,  Hiroyuki Arai ,  Keizo Inoue

发明人： Hideki Adachi ,  Masafumi Tsujimoto ,  Hiroyuki Arai ,  Keizo Inoue

IPC分类号： C12N914

CPC分类号： C12N9/18

摘要： The present invention relates to an isolated human protein having platelet activating factor acetylhydrolase activity.

摘要翻译： 本发明涉及具有血小板活化因子乙酰水解酶活性的分离的人蛋白质。

公开(公告)号：US5880272A

公开(公告)日：1999-03-09

申请号：US961716

申请日：1997-10-31

申请人： Hideki Adachi ,  Masafumi Tsujimoto ,  Keizo Inoue ,  Hiroyuki Arai

发明人： Hideki Adachi ,  Masafumi Tsujimoto ,  Keizo Inoue ,  Hiroyuki Arai

IPC分类号： C12N9/16 ,  C12N9/18 ,  C12N15/09 ,  C12N15/53 ,  C12N9/20 ,  C12N15/55

CPC分类号： C12N9/18

摘要： An oxidized phospholipid degrading enzyme is provided, which plays an important role in the oxygen stress preventive mechanism in organisms. The enzyme hydrolyzes a 1-acyl-2-.omega.-carboxyfatty acid acyl-3-phosphatidylcholine as a substrate at the 2-ester bond thereof to form 1-acyl-2-lyso-3-phosphatidylcholine. The activity of the enzyme is slightly enhanced by 4 mM calcium chloride. The molecular mass of the enzyme is 95.+-.5 kDa (by gel filtration). The enzyme is composed of three subunits whose molecular masses have been found to be 29 kDa, 30 kDa and 45 kDa, respectively, by SDS-polyacrylamide electrophoresis. A gene coding the enzyme is also provided. This gene is important for the synthesis of the enzyme by genetic engineering.

摘要翻译： 提供氧化磷脂降解酶，在生物体的氧应激预防机制中起重要作用。 该酶水解1-酰基-2-巯基脂肪酸酰基-3-磷脂酰胆碱作为其2-酯键的底物，形成1-酰基-2-溶血-3-磷脂酰胆碱。 该酶的活性由4mM氯化钙稍微增强。 酶的分子量为95 +/- 5kDa（通过凝胶过滤）。 该酶由三个亚基组成，其分子量分别通过SDS-聚丙烯酰胺电泳发现为29kDa，30kDa和45kDa。 还提供了编码酶的基因。 该基因对通过遗传工程合成酶非常重要。

公开(公告)号：US5689759A

公开(公告)日：1997-11-18

申请号：US622183

申请日：1996-03-25

申请人： Keizo Isemura ,  Hideki Adachi ,  Tokuharu Kaneko ,  Satoru Kutsuwada

发明人： Keizo Isemura ,  Hideki Adachi ,  Tokuharu Kaneko ,  Satoru Kutsuwada

IPC分类号： G03G15/00

CPC分类号： G03G15/6514 ,  G03G2215/00734

摘要： A copying apparatus provided with a manual sheet feeding device, including an image formation control unit for controlling an image forming operation, a manual input device for designating the size of a copying sheet placed on the manual sheet feeding device, a memory for memorizing the sheet size designated by the manual input device, and a display for displaying the sheet size memorized by the memory. The image formation control unit controls the image forming operation in accordance with the size designated by the manual input device.

摘要翻译： 一种具有手动送纸装置的复印装置，包括用于控制图像形成操作的图像形成控制单元，用于指定放置在手动送纸装置上的复印纸的尺寸的手动输入装置，用于记忆纸张的存储器 由手动输入装置指定的尺寸，以及用于显示由存储器存储的纸张尺寸的显示器。 图像形成控制单元根据由手动输入装置指定的尺寸来控制图像形成操作。