公开(公告)号：US20070196458A1

公开(公告)日：2007-08-23

申请号：US11640139

申请日：2006-12-14

申请人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

发明人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

IPC分类号： A61F13/02 ,  A61L15/16

CPC分类号： A61K9/0014 ,  A61K9/7015 ,  A61L26/0066 ,  A61L26/0076 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/602

摘要： The present invention is drawn to adhesive solidifying formulations for treating neuropathic pain. The formulation can include a drug suitable for treating neuropathic pain, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent capable of facilitating the delivery of the drug at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.

摘要翻译： 本发明涉及用于治疗神经性疼痛的粘合剂固化剂。 制剂可以包括适合于治疗神经性疼痛的药物，溶剂载体和固化剂。 溶剂载体可以包括包含至少一种挥发性溶剂的挥发性溶剂体系和包含至少一种能够在持续的时间内以治疗有效速率递送药物的至少一种非挥发性溶剂的非挥发性溶剂体系。 在挥发性溶剂体系蒸发之前，配方可以具有适用于皮肤表面的粘度。 当施用于皮肤时，在挥发性溶剂体系的至少一部分蒸发后，制剂可以形成固化层。

公开(公告)号：US20070196453A1

公开(公告)日：2007-08-23

申请号：US11640445

申请日：2006-12-14

申请人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

发明人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

IPC分类号： A61K9/70

CPC分类号： A61K9/7015 ,  A61K31/473 ,  A61K31/513 ,  A61K31/573 ,  A61K47/10 ,  A61K47/42

摘要： The present invention is drawn to adhesive formulations, methods of drug delivery, and solidified layers for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can have a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least two non-volatile solvents. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.

摘要翻译： 本发明涉及粘合剂制剂，药物递送方法和用于药物真皮递送的固化层。 制剂可以包括药物，溶剂载体和固化剂。 溶剂载体可以具有包括至少一种挥发性溶剂的挥发性溶剂体系和包含至少两种非挥发性溶剂的非挥发性溶剂体系。 在挥发性溶剂体系蒸发之前，配方可以具有适用于皮肤表面的粘度。 当施用于皮肤时，在挥发性溶剂体系的至少一部分蒸发后，制剂可以形成固化层。

公开(公告)号：US20070196325A1

公开(公告)日：2007-08-23

申请号：US11640101

申请日：2006-12-14

申请人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

发明人： Jie Zhang ,  Kevin Warner ,  Sanjay Sharma

IPC分类号： A61K31/74

CPC分类号： A61K31/74 ,  A61K9/0014 ,  A61K9/7015 ,  A61K31/4174 ,  A61K31/522 ,  A61K47/12 ,  A61K47/18 ,  A61K47/32 ,  A61K47/38

摘要： The present invention is drawn to solidifying adhesive formulations, methods of drug delivery, and solidified layers for dermal delivery of a drug which can treat various skin infections, such as fungal, bacterial, and/or viral skin infections. The formulation can include an anti-infective drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent. The non-volatile solvent system can facilitate the delivery of the drug at therapeutically effective rates for sustained period of time. The non-volatile solvent system can also act as a plasticizer for the solidifying agent. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.

摘要翻译： 本发明涉及固化粘合剂制剂，药物递送方法和用于真皮递送药物的固化层，其可以治疗各种皮肤感染，例如真菌，细菌和/或病毒性皮肤感染。 制剂可包括抗感染药物，溶剂载体和固化剂。 溶剂载体可以包括包含至少一种挥发性溶剂的挥发性溶剂体系和包含至少一种非挥发性溶剂的非挥发性溶剂体系。 非挥发性溶剂体系可以有助于以治疗有效率持续持续的时间递送药物。 非挥发性溶剂体系也可以作为固化剂的增塑剂。 在挥发性溶剂体系蒸发之前，配方可以具有适用于皮肤表面的粘度。 当施用于皮肤时，在挥发性溶剂体系的至少一部分蒸发后，制剂可以形成固化层。

公开(公告)号：US20070189980A1

公开(公告)日：2007-08-16

申请号：US11640135

申请日：2006-12-14

申请人： Jie Zhang ,  Kevin Wamer ,  Sanjay Sharma

发明人： Jie Zhang ,  Kevin Wamer ,  Sanjay Sharma

IPC分类号： A61K31/573 ,  A61K31/513 ,  A61K31/473 ,  A61K9/00

CPC分类号： A61K9/7015 ,  A61K31/473 ,  A61K31/513 ,  A61K31/573 ,  A61K47/10 ,  A61K47/42

摘要： The present invention is drawn to adhesive solidifying formulations, methods of drug delivery, and solidified layers for topical delivery of drugs for treating alopecia. The formulation can include a drug for treating alopecia, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent which is capable of facilitating the delivery of the drug at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface as a layer prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.

摘要翻译： 本发明涉及胶粘剂凝固制剂，药物递送方法和用于局部递送用于治疗脱发的药物的固化层。 制剂可以包括治疗脱发的药物，溶剂载体和固化剂。 溶剂载体可以包括具有一种或多种挥发性溶剂的挥发性溶剂体系和具有一种或多种非挥发性溶剂的非挥发性溶剂体系，所述非挥发性溶剂系统能够在持续的时间内以有效的速率递送药物 时间。 制剂可以具有适于在蒸发挥发性溶剂体系之前作为层使用于皮肤表面的粘度。 当施用于皮肤时，在挥发性溶剂体系的至少一部分蒸发后，制剂可以形成固化层。

公开(公告)号：US07253611B2

公开(公告)日：2007-08-07

申请号：US10534111

申请日：2002-11-08

申请人： Liyao Ma ,  Yinghua Chen ,  Yingchun Jiang ,  Jie Zhang

发明人： Liyao Ma ,  Yinghua Chen ,  Yingchun Jiang ,  Jie Zhang

IPC分类号： G01B7/14

CPC分类号： G01D5/145 ,  G01B3/205 ,  G01D5/2451

摘要： This invention relates to a magnetic displacement measurement device, which comprises a ruler body and a vernier, wherein a magnetic main ruler is fixed on the ruler body, and a secondary ruler is fixed on the vernier; the secondary ruler comprises a magnetic sensor and a measurement circuit thereon; said magnetic sensor is composed of magnetoresistances; said measurement circuit comprises at least two measurement bridges composed of magnetoresistances; the movement distance of the vernier is displayed on the display screen of the device after being detected by the magnetic sensor and being processed by the measurement circuit. The magnetic displacement measurement device provided by the invention not only can normally work in the wet and oil polluted environment, but also has the advantages of simple structure, convenient manufacture, low price, low power consumption and high precision.

摘要翻译： 本发明涉及一种磁位移测量装置，其包括标尺体和游标，其中磁性主尺固定在标尺体上，二尺固定在游标上; 二次尺在其上包括磁传感器和测量电路; 所述磁传感器由磁阻组成; 所述测量电路包括至少两个由磁阻组成的测量桥; 在通过磁传感器检测并被测量电路处理之后，游标的移动距离被显示在设备的显示屏幕上。 本发明提供的磁位移测量装置不仅可以在湿油污染环境中正常工作，而且结构简单，制造方便，价格低廉，功耗低，精度高等优点。

公开(公告)号：US20070090858A1

公开(公告)日：2007-04-26

申请号：US11259480

申请日：2005-10-26

申请人： Paul Brazis ,  Daniel Gamota ,  Kin Tsui ,  John Szczech ,  Jie Zhang

发明人： Paul Brazis ,  Daniel Gamota ,  Kin Tsui ,  John Szczech ,  Jie Zhang

IPC分类号： H03K19/094

CPC分类号： H03K19/01721 ,  H03K19/09441

摘要： An inverter circuit (500) having a drive transistor (102) that operably couples to a voltage bias input (101) (and where that drive transistor controls the inverter circuit output by opening and closing a connection between the output (105) and ground (104)) is further operably coupled to a feedback switch (401). In a preferred approach the feedback switch is itself also operably coupled to the voltage bias input and the output and preferably serves, when the drive transistor is switched “off,” to responsively couple the voltage bias input to the drive transistor in such a way as to cause a gate terminal of the drive transistor to have its polarity relative to a source terminal of the drive transistor reversed and hence permit the inverter circuit to operate across a substantially full potential operating range of the drive transistor.

摘要翻译： 一种具有可操作地耦合到电压偏置输入（101）的驱动晶体管（102）的逆变器电路（500），并且其中该驱动晶体管通过打开和关闭输出（105）和地（ 104））进一步可操作地耦合到反馈开关（401）。 在优选的方法中，反馈开关本身也可操作地耦合到电压偏置输入端和输出端，并且优选地在驱动晶体管被切断时关断，以将电压偏置输入以驱动晶体管的方式耦合到驱动晶体管， 以使驱动晶体管的栅极端子相对于驱动晶体管的源极端子的极性相反，从而允许逆变器电路在驱动晶体管的基本上全部的电位工作范围内工作。

公开(公告)号：US20070053148A1

公开(公告)日：2007-03-08

申请号：US11344463

申请日：2006-01-30

申请人： Zheng Shi ,  Jie Zhang ,  Chien-Li Tsai

发明人： Zheng Shi ,  Jie Zhang ,  Chien-Li Tsai

IPC分类号： G06F1/16

CPC分类号： G06F1/187

摘要： A mounting apparatus is provided for mounting a data storage device in a computer enclosure. The data storage device is mounted with a locking member. The mounting apparatus includes a restricting portion arranged in the computer enclosure, a locking portion movably disposed in the restricting portion, a resilient element disposed between the locking portion and the restricting portion, and a resilient pushing portion disposed between the data storage device and the restricting portion. The locking member drives the locking portion to deform the resilient element, and then engages with the locking portion. When the locking member disengages from the locking portion, the resilient pushing portion drives the data storage device outwardly.

摘要翻译： 提供一种用于将数据存储装置安装在计算机机壳中的安装装置。 数据存储装置安装有锁定构件。 安装装置包括设置在计算机机壳中的限制部分，可移动地设置在限制部分中的锁定部分，设置在锁定部分和限制部分之间的弹性元件，以及设置在数据存储装置与限制部件之间的弹性推动部分 一部分。 锁定构件驱动锁定部分以使弹性元件变形，然后与锁定部分接合。 当锁定构件与锁定部分脱离时，弹性推动部分向外驱动数据存储装置。

公开(公告)号：US20070042392A1

公开(公告)日：2007-02-22

申请号：US11218141

申请日：2005-08-31

申请人： Y. Tang ,  Chenghua Liu ,  Vinod Asundi ,  Rui-hong Chen ,  Yunqing Ma ,  Feiyan Ren ,  Jian-Rui Wang ,  Thomas Wehrman ,  Chongjun Xu ,  Aidong Xue ,  Yonghong Yang ,  Jie Zhang ,  Qing Zhao ,  Ping Zhou ,  Radoje Drmanac ,  Yi-Cheng Cao ,  Dunrui Wang ,  Zhi Wang ,  Ryle Goodrich

发明人： Y. Tang ,  Chenghua Liu ,  Vinod Asundi ,  Rui-hong Chen ,  Yunqing Ma ,  Feiyan Ren ,  Jian-Rui Wang ,  Thomas Wehrman ,  Chongjun Xu ,  Aidong Xue ,  Yonghong Yang ,  Jie Zhang ,  Qing Zhao ,  Ping Zhou ,  Radoje Drmanac ,  Yi-Cheng Cao ,  Dunrui Wang ,  Zhi Wang ,  Ryle Goodrich

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q1/6883 ,  C12Q2600/136

摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.

公开(公告)号：US20070010118A1

公开(公告)日：2007-01-11

申请号：US11478644

申请日：2006-07-03

申请人： Zhong Li ,  Wolfgang Pabst ,  Jie Zhang

发明人： Zhong Li ,  Wolfgang Pabst ,  Jie Zhang

IPC分类号： H01R33/02

CPC分类号： H01J5/56 ,  H01J5/48 ,  H01J61/327 ,  H01R33/08

摘要： A fluorescent lamp mainly includes a lamp tube (1), a tube holder (2) and a lamp cap (3), wherein the tube holder (2) has one end fixed to the lamp cap (3) and the other end assembled to the lamp tube (1), characterized in that the walls (2-6) of the tube holder (2) are moved outward in radial direction, thereby substantially circularity gaps (2-3) are formed between the walls (2-6) and the end parts (1-2) of the lamp tube (1), and that the gaps (2-3) are filled with suitable heat insulating material (5) having low heat conduction and resistance to high temperature. An advantage of the lamp is that the hottest parts (2-2) of the tube holder (2) no longer melt and thereby safety is ensured, and that smoke or blackening will not appear any longer. Such fluorescent lamp will enjoy more popularity of the users.

摘要翻译： 荧光灯主要包括灯管（1），管保持器（2）和灯头（3），其中管保持器（2）的一端固定到灯头（3），另一端组装成 所述灯管（1）的特征在于，所述管保持器（2）的壁（2-6）沿径向向外移动，从而在所述壁（2-6）之间形成大致圆形的间隙（2-3） 和灯管（1）的端部部分（1-2），并且间隙（2-3）填充有具有低导热性和耐高温性的合适的隔热材料（5）。 灯的优点在于，管座（2）的最热的部件（2 - 2）不再熔化，从而确保了安全性，并且不再出现烟雾或变黑。 这样的荧光灯将会更受欢迎的用户。

公开(公告)号：US07138240B2

公开(公告)日：2006-11-21

申请号：US10141725

申请日：2002-05-09

申请人： Lawrence S. Barak ,  Marc G. Caron ,  Stephen S. Ferguson ,  Jie Zhang

发明人： Lawrence S. Barak ,  Marc G. Caron ,  Stephen S. Ferguson ,  Jie Zhang

IPC分类号： G01N33/566 ,  G01N21/76 ,  G01N33/53

CPC分类号： G01N33/5008 ,  C07K14/47 ,  C07K2319/00 ,  C07K2319/60 ,  C12N15/62 ,  G01N2333/726 ,  G01N2333/91

摘要： Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G Protein-coupled receptor kinase (GRK) activity, and compounds that interact with components of the GPCR regulatory process.

摘要翻译： 描述了体内和体外检测G蛋白偶联受体（GPCR）活性的方法; 测定GPCR活性的方法; 和筛选GPCR配体，G蛋白偶联受体激酶（GRK）活性和与GPCR调节过程的组分相互作用的化合物的方法。