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公开(公告)号:US6057431A
公开(公告)日:2000-05-02
申请号:US930677
申请日:1997-12-22
CPC分类号: C07H21/00
摘要: The present invention provides a compound of general formula (I): ##STR1## wherein X represents group (II) or (III): ##STR2## wherein Y represents a leaving group and Z represents an oligonucleotide. The compound can specifically transfer oligonucleotides to cells which specifically recognize a specified saccharide construction. Accordingly, the compound can be used as an antiviral agent or an antitumor agent.
摘要翻译: PCT No.PCT / JP96 / 00868 Sec。 371 1997年12月22日第 102(e)日期1997年12月22日PCT 1996年3月29日PCT公布。 WO96 / 30386 PCT公开号 日期:1996年10月3日本发明提供通式(I)的化合物:其中X表示基团(II)或(III):其中Y表示离去基团,Z表示寡核苷酸。 该化合物可以将寡核苷酸特异性转移到特异性识别特定糖结构的细胞中。 因此,该化合物可以用作抗病毒剂或抗肿瘤剂。
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62.
公开(公告)号:US5756568A
公开(公告)日:1998-05-26
申请号:US748441
申请日:1996-11-13
申请人: Yoshitsugu Morita , Atsushi Sasaki
发明人: Yoshitsugu Morita , Atsushi Sasaki
CPC分类号: C08J3/124 , B29B9/16 , C08J3/203 , C08J2383/04 , Y10T428/2991 , Y10T428/2995 , Y10T428/2998
摘要: There is disclosed a composite powder composition which has excellent flowability and water repellency and finds utility as a modifier for paints and organic resins, said composition comprising: (A) 100 parts by weight of a cured silicone powder that has an average particle size of 0.1 to 100 micrometers and contains a non-crosslinking silicone oil; and (B) 0.1 to 100 parts by weight of a microfine inorganic powder, said inorganic powder being coated on the surface of said cured silicone powder.
摘要翻译: 公开了具有优异的流动性和防水性的复合粉末组合物,可用作油漆和有机树脂的改性剂,所述组合物包含:(A)100重量份平均粒径为0.1的固化的硅氧烷粉末 至100微米,并含有非交联硅油; 和(B)0.1至100重量份的微细无机粉末,所述无机粉末涂覆在所述固化的硅氧烷粉末的表面上。
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公开(公告)号:US5719539A
公开(公告)日:1998-02-17
申请号:US294711
申请日:1994-08-23
申请人: Toshio Ishizaki , Atsushi Sasaki , Yuki Satoh , Hiroshi Kushitani , Hideaki Nakakubo , Toshiaki Nakamura , Kimio Aizawa , Takashi Fujino
发明人: Toshio Ishizaki , Atsushi Sasaki , Yuki Satoh , Hiroshi Kushitani , Hideaki Nakakubo , Toshiaki Nakamura , Kimio Aizawa , Takashi Fujino
CPC分类号: H01P1/20345 , H01P1/20381 , H01P1/2056 , H01P1/2135
摘要: A dielectric antenna duplexer used in a high frequency radio device such as a portable telephone, and a dielectric filter for forming the duplexer of the SIR (stepped impedance resonator) composed by cascade connection of first transmission lines having one end grounded and second transmission lines having one end open and lower in characteristic impedance than in the first transmission lines, first transmission lines and second transmission lines are individually coupled in electromagnetic field, thereby forming an antenna duplexer and a dielectric filter of small insertion loss, high bandwidth selectivity, excellent band pass characteristic, and low cost.
摘要翻译: 在诸如便携式电话的高频无线电设备中使用的介质天线双工器和用于形成由具有一端接地的第一传输线和第二传输线的级联连接的SIR(阶梯式阻抗谐振器)的双工器的介质滤波器, 一端的特征阻抗比第一传输线的开路低,第一传输线和第二传输线分别在电磁场中耦合,从而形成一个天线双工器和介质滤波器,其插入损耗小,带宽选择性好,带通优良 特点,成本低。
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公开(公告)号:US5620976A
公开(公告)日:1997-04-15
申请号:US449739
申请日:1995-05-25
申请人: Hachiro Sugimoto , Masahiro Yonaga , Norio Karibe , Youichi Iimura , Satoshi Nagato , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Takashi Kosasa , Kumi Uchikoshi , Kiyomi Yamatsu
发明人: Hachiro Sugimoto , Masahiro Yonaga , Norio Karibe , Youichi Iimura , Satoshi Nagato , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Takashi Kosasa , Kumi Uchikoshi , Kiyomi Yamatsu
IPC分类号: A61K31/40 , A61K31/00 , A61K31/395 , A61K31/42 , A61K31/423 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/4985 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/535 , A61K31/536 , A61K31/5365 , A61K31/5377 , A61K31/55 , A61P9/00 , A61P25/00 , A61P25/02 , A61P25/28 , A61P43/00 , C07D207/16 , C07D263/58 , C07D265/18 , C07D265/26 , C07D401/04 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/06 , C07D413/12 , C07D413/14 , C07D471/04 , C07D475/02 , C07D487/04 , C07D495/04 , C07D498/04 , C12N9/99
CPC分类号: C07D401/06 , C07D401/14 , C07D413/06 , C07D413/14 , C07D471/04 , C07D487/04 , C07D495/04
摘要: The cyclic amide derivative is defined by the formula (I) or a salt thereof: R.sup.1 --(CH2)n--Z in which R.sup.1 is a group derived from a cyclic amide compound, substituted or unsubstituted, n is zero or an integer of 1 to 10 and Z is ##STR1## R.sup.2 being an aryl, a substituted aryl, a cycloalkyl or a heterocyclic group, m being an integer of 1 to 6, R.sup.3 being hydrogen or a lower alkyl, R.sup.4 being an aryl or a substituted aryl, a cycloalkyl or a heterocyclic group, p being an integer of 1 to 6, provided that the cyclic amide compound is quinazoline-on or quinazoline-dion, R2 and R4 are neither aryl nor substituted aryl. The cyclic amide compound is pharmacologically effective to prevent and treat diseases due to insufficiency of the central choline functions.
摘要翻译: 环酰胺衍生物由式(I)或其盐定义:R 1(CH 2)n Z,其中R 1是衍生自环状酰胺化合物的基团,取代或未取代的,n为0或1〜10的整数 Z为芳基,取代芳基,环烷基或杂环基,m为1〜6的整数,R3为氢或低级烷基,R4为芳基或取代芳基,环烷基 或杂环基,p为1〜6的整数,条件是环酰胺化合物为喹唑啉或喹唑啉二酮,R2和R4既不是芳基也不是取代的芳基。 环酰胺化合物在预防和治疗由于中枢胆碱功能不足引起的疾病方面具有药理作用。
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公开(公告)号:US5492945A
公开(公告)日:1996-02-20
申请号:US314484
申请日:1994-09-28
IPC分类号: C08J3/12 , C08K3/36 , C08L83/04 , C09D183/04 , C08K9/00
CPC分类号: C08J3/124 , C08J2383/04
摘要: There is disclosed a process comprising(I) preparing a water-based dispersion of(A) a cured silicone powder having an average particle diameter of 0.1 to 200 micrometers and(B) an amorphous silica micropowder that has an average particle diameter not exceeding 1 micrometer and a surface silanol group density of at least 2 silanol groups per 100 square angstroms;(II) heating said water-based dispersion; and(III) removing the water from said dispersion, thereby producing a cured silicone rubber composition wherein the silica micropowder is immobilized on the surface of the cured silicone powder.
摘要翻译: 公开了一种方法,其包括(I)制备(A)平均粒径为0.1至200微米的固化的硅氧烷粉末和(B)平均粒径不超过1的无定型二氧化硅微粉的水性分散体 千分尺,表面硅烷醇基密度为每100平方埃至少2个硅烷醇基; (II)加热所述水性分散体; 和(III)从所述分散体中除去水,从而制备固化的硅橡胶组合物,其中将二氧化硅微粉固定在固化的硅氧烷粉末的表面上。
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公开(公告)号:US5475014A
公开(公告)日:1995-12-12
申请号:US204326
申请日:1994-03-08
申请人: Kozo Akasaka , Akiharu Kajiwara , Satoshi Nagato , Youichi Iimura , Ichirou Yoshida , Atsushi Sasaki , Masanori Mizuno , Atsuhiko Kubota , Takaki Kagaya , Mariko Komatsu
发明人: Kozo Akasaka , Akiharu Kajiwara , Satoshi Nagato , Youichi Iimura , Ichirou Yoshida , Atsushi Sasaki , Masanori Mizuno , Atsuhiko Kubota , Takaki Kagaya , Mariko Komatsu
IPC分类号: A61K31/42 , A61K31/423 , A61K31/425 , A61K31/445 , A61P25/24 , A61P25/26 , C07D263/56 , C07D263/57 , C07D263/58 , C07D417/04 , C07D417/14 , C07D417/10
CPC分类号: C07D263/57 , C07D417/04 , C07D417/14
摘要: An oxazolidone derivative represented by formula (I) which has a monoamine oxidase inhibition effect: ##STR1## {wherein A and B each represents a nitrogen atom, a sulfur atom or an oxygen atom, with the proviso than at least one of A and B must be a nitrogen atom,R.sup.1 represents a group of the formula: ##STR2## (in which n and m each represents 0 or an integer of 1 to 4, and R.sup.3 and R.sup.4 each represents a hydrogen atom, a hydroxyl group, a lower alkyl group, etc. ), a group represented by the formula: ##STR3## (in which p and q each represents 0 or an integer of 1 to 4 and X represents an oxygen atom, sulfur atom, etc.) and a group represented by the formula: ##STR4## R.sup.2 represents a hydrogen atom or a lower alkyl group}.
摘要翻译: 具有单胺氧化酶抑制作用的式(I)表示的恶唑烷酮衍生物:其中A和B各自表示氮原子,硫原子或氧原子,条件是至少一个 A和B必须是氮原子,R 1表示下式的基团:其中n和m各自表示0或1至4的整数,并且R 3和R 4各自表示氢原子,羟基 ,低级烷基等),由下式表示的基团:其中p和q各自表示0或1〜4的整数,X表示氧原子,硫原子等)和 由下式表示的基团:
R 2表示氢原子或低级烷基}。 -
公开(公告)号:US5292735A
公开(公告)日:1994-03-08
申请号:US715754
申请日:1991-06-14
申请人: Hachiro Sugimoto , Masahiro Yonaga , Norio Karibe , Youichi Iimura , Satoshi Nagato , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Takashi Kosasa , Kumi Uchikoshi , Kiyomi Yamatsu
发明人: Hachiro Sugimoto , Masahiro Yonaga , Norio Karibe , Youichi Iimura , Satoshi Nagato , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Takashi Kosasa , Kumi Uchikoshi , Kiyomi Yamatsu
IPC分类号: A61K31/40 , A61K31/00 , A61K31/395 , A61K31/42 , A61K31/423 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/4985 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/535 , A61K31/536 , A61K31/5365 , A61K31/5377 , A61K31/55 , A61P9/00 , A61P25/00 , A61P25/02 , A61P25/28 , A61P43/00 , C07D207/16 , C07D263/58 , C07D265/18 , C07D265/26 , C07D401/04 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/06 , C07D413/12 , C07D413/14 , C07D471/04 , C07D475/02 , C07D487/04 , C07D495/04 , C07D498/04 , C12N9/99
CPC分类号: C07D401/06 , C07D401/14 , C07D413/06 , C07D413/14 , C07D471/04 , C07D487/04 , C07D495/04
摘要: The cyclic amide derivative is defined by the formula (I) or a salt thereof: R1--(CH2)n-z in which R1 is a group derived from a cyclic amide compound, substituted or unsubstituted, n is zero or an integer of 1 to 10 and Z is ##STR1## R2 being an aryl, a substituted aryl, a cycloalkyl or a heterocyclic group, m being an integer of 1 to 6, R3 being hydrogen or a lower alkyl, R4 being an aryl or a substituted aryl, a cycloalkyl or a heterocyclic group, p being an integer of 1 to 6, provided that the cyclic amide compound is quinazoline-on or quinazoline-dion, R2 and R4 are neither aryl nor substituted aryl. The cyclic amide compound is pharmacologically effective to prevent and treat diseases due to insufficiency of the central choline functions.
摘要翻译: 环酰胺衍生物由式(I)或其盐定义:R 1(CH 2)n z,其中R 1是衍生自环状酰胺化合物的基团,被取代或未取代的,n为0或1〜10的整数 Z为(*化学结构*)(1)或(*化学结构*)(2)R2为芳基,取代芳基,环烷基或杂环基,m为1〜6的整数,R3为氢 或低级烷基,R4为芳基或取代芳基,环烷基或杂环基,p为1〜6的整数,条件是环酰胺化合物为喹唑啉或喹唑啉二酮,R2和R4均不为 芳基或取代的芳基。 环酰胺化合物在预防和治疗由于中枢胆碱功能不足引起的疾病方面具有药理作用。
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68.
公开(公告)号:US4895841A
公开(公告)日:1990-01-23
申请号:US209339
申请日:1988-06-20
申请人: Hachiro Sugimoto , Yutaka Tsuchiya , Kunizou Higurashi , Norio Karibe , Youichi Iimura , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Shin Araki , Takashi Kosasa , Atsuhiko Kubota , Michiko Kosasa , Kiyomi Yamatsu
发明人: Hachiro Sugimoto , Yutaka Tsuchiya , Kunizou Higurashi , Norio Karibe , Youichi Iimura , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Shin Araki , Takashi Kosasa , Atsuhiko Kubota , Michiko Kosasa , Kiyomi Yamatsu
IPC分类号: C07D211/18 , A61K31/452 , A61P25/02 , C07D207/09 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/32 , C07D211/34 , C07D211/44 , C07D211/70 , C07D211/76 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D471/04
CPC分类号: C07D401/06 , C07D207/09 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/32 , C07D211/34 , C07D211/44 , C07D211/70 , C07D211/76 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D471/04 , Y10S152/90
摘要: A cyclic amine compound is defined by the formula: ##STR1## in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is --(CHR22)r--, R22 being H or methyl, --CO--(CHR22)r--, .dbd.(CH--CH.dbd.CH)b--, .dbd.CH--(CH2)c-- or .dbd.(CH--CH)d.dbd. and the ring including T and Q is piperidine. The compound is useful to treat senile dementia.
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公开(公告)号:US4669976A
公开(公告)日:1987-06-02
申请号:US763012
申请日:1985-08-06
申请人: Hirofumi Hatano , Masayasu Yamazaki , Atsushi Sasaki , Keigo Mikami, deceased , Kiyomichi Taoda , Mitsuharu Murakami
发明人: Hirofumi Hatano , Masayasu Yamazaki , Atsushi Sasaki , Keigo Mikami, deceased , Kiyomichi Taoda , Mitsuharu Murakami
CPC分类号: C04B7/434 , F27B7/205 , F27B7/2058
摘要: There is here disclosed a calcining apparatus for a powdery material comprising a first preheating series composed of a calcining kiln and preheaters at a plurality of stages for heating the powdery material with an exhaust gas from the calcining kiln, a second preheating series composed of other preheaters at a plurality of stages for heating the powdery material with an exhaust gas from a rotary kiln, and a gas carrying pipe for connecting the first and second prehating series in the middle thereof, a flow path for the powdery material being adapted so that the powdery material fed to each series may be led into the rotary kiln via a combining duct disposed in front of the undermost preheaters in both the series and then via the undermost portions of both the series. Further, disclosed is a calcining apparatus for a powdery material in which a sub-calcining kiln and a calcining chamber are disposed on an exhaust gas pipe extending from a rotary kiln. Still futher, disclosed is a calcining apparatus for a powdery material in which a calcining chamber is disposed, and a flow path through which the powdery material fed to first and second preheating series passes is provided with a powdery material carrying pipe for connecting both series in front of the second preheaters from the bottom in both series, and is further provided with a combining duct for combining powdery materials from both series in the rear of the second preheaters from the bottom in both series.
摘要翻译: 这里公开了一种用于粉末材料的煅烧装置,包括由煅烧窑组成的第一预热系列和用于从煅烧窑炉排出废气的多个阶段的预热器,由其它预热器组成的第二预热系列 在用于从回转窑排出气体的情况下加热粉末材料的多个阶段,以及用于在其中间连接第一和第二预分离系列的气体输送管,该粉末材料的流路适于使粉末状材料 馈送到每个系列的材料可以通过布置在不连续的预热器前面的组合管道被引入回转窑,并且然后经过两个系列的最下部分。 此外,公开了一种粉末材料的煅烧装置,其中在从回转窑延伸的废气管上设置有次煅烧窑和煅烧室。 更进一步地,公开了一种用于粉末状材料的煅烧装置,其中设置有煅烧室,并且向第一和第二预热系列供给的粉末材料通过的流路设置有用于将两个系列连接的粉末输送管 第二预热器的前部从两个串联的底部进一步设置有组合管道,用于从两个串联的底部的第二预热器的后部组合来自两个系列的粉末材料。
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公开(公告)号:US4623311A
公开(公告)日:1986-11-18
申请号:US757926
申请日:1985-07-22
CPC分类号: F27B7/205
摘要: There is here disclosed a calcining apparatus for a powdery material comprising a first preheating series composed of a calcining kiln and preheaters at a plurality of stages for heating the powdery material with an exhaust gas from the calcining kiln, a second preheating series composed of a calcining chamber disposed on an exhaust gas pipe extending from a rotary kiln and other preheaters at a plurality of stages for heating the powdery material with an exhaust gas from a rotary kiln, a gas carrying pipe for connecting the first and second preheating series in the middle thereof, and a flow path through which the powdery material fed to first and second preheating series passes is provided with a powdery material carrying pipe for connecting both series in front of second preheaters from the bottom in both series, and is further provided with a combining duct for combining powdery materials from both the series in the rear of the second preheaters from the bottom in both series, the flow path for the powdery material being adapted so that the powdery material fed to each series may be led into the rotary kiln via the combining duct and then via the undermost traveling portions of both series.
摘要翻译: 这里公开了一种用于粉末材料的煅烧装置,其包括由煅烧窑组成的第一预热系列和多个阶段的预热器,用于将来自煅烧窑的废气加热到粉末材料,第二预热系列由煅烧 设置在从旋转窑等多个预热器延伸的排气管上,多个阶段用于从旋转窑中排出废气来加热粉末状材料,用于将第一和第二预热系列在其中间连接的气体输送管 并且供给第一和第二预热系列的粉末材料经过的流路设置有粉末状材料承载管,用于从两个串联的底部将第二预热器前面的两个串联连接起来,并且还设置有组合管 用于从两个系列的底部组合来自第二预热器后部的系列的粉末材料 粉末材料的流动路径适于使得供给到每个系列的粉末材料可以经由合并管道然后经由两个系列的最下部行进部分引入回转窑。
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