公开(公告)号：US20180214847A1

公开(公告)日：2018-08-02

申请号：US15938009

申请日：2018-03-28

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16

Abstract: A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch.

公开(公告)号：US09974896B2

公开(公告)日：2018-05-22

申请号：US14642847

申请日：2015-03-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  SuPing Lyu ,  Eric Grovender ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: B01D11/00 ,  A61M1/16 ,  C01B25/45 ,  B01J39/09

CPC classification number: A61M1/1696 ,  B01J39/09 ,  C01B25/45

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.

公开(公告)号：US20180021501A1

公开(公告)日：2018-01-25

申请号：US15723676

申请日：2017-10-03

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura ,  Thomas E. Meyer ,  VenKatesh R. Manda

IPC: A61M1/28

Abstract: The invention relates to devices, systems, and methods for generating a peritoneal dialysate having specified concentrations of one or more solutes. The devices, systems and methods use conductivity sensors, flow meters, and composition sensors to control addition of osmotic agents and ion concentrates into a peritoneal dialysate generation flow path.

公开(公告)号：US20180021500A1

公开(公告)日：2018-01-25

申请号：US15723550

申请日：2017-10-03

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura

IPC: A61M1/28 ,  A61M1/16

Abstract: The invention relates to devices, systems, and methods for temperature regulation in generating peritoneal dialysate and using a peritoneal dialysis (PD) system. The system can use a heater and temperature sensors to regulate the temperature of fluid within the PD system.

公开(公告)号：US20170281846A1

公开(公告)日：2017-10-05

申请号：US15478569

申请日：2017-04-04

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61K31/19 ,  A61K31/715 ,  A61K33/14 ,  A61L2/10 ,  A61K31/7004

CPC classification number: A61M1/282 ,  A61K31/19 ,  A61K31/7004 ,  A61K31/715 ,  A61K33/14 ,  A61L2/10 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/1686 ,  A61M1/28 ,  A61M1/287 ,  A61M2205/3331 ,  A61M2205/3337 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/75 ,  A61M2205/7518 ,  A61M2209/084 ,  A61M2209/10 ,  C02F1/283 ,  C02F1/325 ,  C02F1/42 ,  C02F1/441 ,  C02F1/442 ,  C02F1/444 ,  C02F2303/04

Abstract: Systems and methods of generating peritoneal dialysate and using the peritoneal dialysate with an integrated cycler are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare peritoneal dialysate from source water and infuse the prepared peritoneal dialysate into a patient with an integrated cycler. Optional dialysate storage containers are provided for storage of the peritoneal dialysate prior to use.

公开(公告)号：US20150367051A1

公开(公告)日：2015-12-24

申请号：US14633852

申请日：2015-02-27

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/14

CPC classification number: A61M1/1696

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

Abstract translation: 用于补充用于吸附剂透析的吸附剂盒中的脲酶的装置和方法。 吸附剂盒构造成允许将一定量的脲酶加入到吸附剂盒中。 可以将脲酶溶液注入吸附剂盒中以补充含脲酶的模块，或者可以将固体脲酶加入到吸附剂盒中。 吸附剂模块还可以包含用于从废透析液中去除尿素以外的毒素的其它可再充电的吸附剂材料。

公开(公告)号：US11673118B2

公开(公告)日：2023-06-13

申请号：US17330758

申请日：2021-05-26

Applicant: Medtronic, Inc

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16 ,  B01J20/22 ,  B01J20/06 ,  B01J20/02 ,  B01J20/20

CPC classification number: B01J20/28052 ,  A61M1/1696 ,  B01J20/0211 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22 ,  B01J2220/66

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.

公开(公告)号：US11607669B2

公开(公告)日：2023-03-21

申请号：US16691924

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/34 ,  B01J20/02 ,  A61M1/16

Abstract: The invention relates to devices, systems, and methods for precision recharging of sorbent materials in a sorbent module. The devices, systems, and methods use manufacturing characteristics of the sorbent module to set recharge parameters used in recharging the sorbent material.

公开(公告)号：US20220296794A1

公开(公告)日：2022-09-22

申请号：US17208251

申请日：2021-03-22

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61M1/16

Abstract: The invention relates to systems and methods for generation and use of peritoneal dialysis fluid. The peritoneal dialysis fluid is generated by dissolving solids or diluting concentrated liquids in a single container having all components of the final peritoneal dialysis fluid.

公开(公告)号：US11103626B2

公开(公告)日：2021-08-31

申请号：US15588806

申请日：2017-05-08

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Martin T. Gerber ,  Christopher M. Hobot ,  Thomas E. Meyer ,  Jin Huang

IPC: A61M1/16 ,  A61M1/26 ,  A61K33/00 ,  A61K33/14 ,  A61M1/34

Abstract: The invention relates to an infusate holder for use in dialysis. The infusate holder can include one or more interior compartments for holding infusate containers or infusates. The interior compartments are aligned to cooperate with fluid connectors of a dialysis system, ensuring that the proper infusates are added to the dialysis system at a proper location.