公开(公告)号：US10575748B2

公开(公告)日：2020-03-03

申请号：US16051779

申请日：2018-08-01

Applicant: Medtronic, Inc.

Inventor： Elise J. Higgins ,  Mark L. Brown ,  Jian Cao

IPC: A61B5/04 ,  A61B5/0464 ,  A61B5/00 ,  A61B5/024 ,  A61B5/042 ,  A61B5/0456 ,  A61B5/046 ,  A61N1/39 ,  A61B5/0472

Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.

公开(公告)号：US20200038671A1

公开(公告)日：2020-02-06

申请号：US16050928

申请日：2018-07-31

Applicant: Medtronic, Inc.

Inventor： Randal C. Schulhauser ,  Jian Cao ,  David Probst ,  Daniel Hahn ,  Eric C. Maass ,  Patrick W. Kinzie

IPC: A61N1/39 ,  A61N1/04 ,  A61B5/00 ,  A61B5/145 ,  A61B5/0476 ,  A61B5/021 ,  A61B5/024 ,  A61B5/08 ,  A61B5/11

Abstract: In some examples, an apparatus configured to be worn by a patient for cardiac defibrillation comprises sensing electrodes configured to sense a cardiac signal of the patient, defibrillation electrodes, therapy delivery circuitry configured to deliver defibrillation therapy to the patient via the defibrillation electrodes, communication circuitry configured to receive data of at least one physiological signal of the patient from at least one sensing device separate from the apparatus, a memory configured to store the data, the cardiac signal, and a machine learning algorithm, and processing circuitry configured to apply the machine learning algorithm to the data and the cardiac signal to probabilistically-determine at least one state of the patient and determine whether to control delivery of the defibrillation therapy based on the at least one probabilistically-determined patient state.

公开(公告)号：US20190351246A1

公开(公告)日：2019-11-21

申请号：US16531685

申请日：2019-08-05

Applicant: Medtronic, Inc.

Inventor： Robert W. Stadler ,  Jian Cao

IPC: A61N1/39 ,  A61B5/0464

Abstract: A medical device is configured to deliver an electrical stimulation pulse to a heart of a patient, determine a pre-stimulation cardiac event amplitude prior to delivering the electrical stimulation pulse and adjust a cardiac event sensing threshold according to a first post-stimulation decay sequence in response to the electrical stimulation pulse delivery. The first post-stimulation decay sequence is controlled by a sensing module of the medical device according to a first set of sensing control parameters including at least one sensing control parameter based on the pre-stimulation cardiac event amplitude.

公开(公告)号：US10369372B2

公开(公告)日：2019-08-06

申请号：US14519220

申请日：2014-10-21

Applicant: Medtronic, Inc.

Inventor： Robert W. Stadler ,  Jian Cao

IPC: A61N1/39 ,  A61B5/0464 ,  A61B5/0452 ,  A61B5/046 ,  A61N1/37

Abstract: A medical device is configured to deliver an electrical stimulation pulse to a heart of a patient, determine a pre-stimulation cardiac event amplitude prior to delivering the electrical stimulation pulse and adjust a cardiac event sensing threshold according to a first post-stimulation decay sequence in response to the electrical stimulation pulse delivery. The first post-stimulation decay sequence is controlled by a sensing module of the medical device according to a first set of sensing control parameters including at least one sensing control parameter based on the pre-stimulation cardiac event amplitude.

公开(公告)号：US10252071B2

公开(公告)日：2019-04-09

申请号：US15142171

申请日：2016-04-29

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Timothy A. Ebeling ,  Saul E. Greenhut ,  Michael W. Heinks ,  Irving J. Sanchez ,  Paul R. Solheim ,  Xusheng Zhang ,  Gerald P. Arne

IPC: A61N1/39 ,  A61N1/05 ,  A61B5/0456 ,  A61N1/362 ,  A61N1/365

Abstract: An implantable medical device system capable of sensing cardiac electrical signals includes a sensing circuit, a therapy delivery circuit and a control circuit. The sensing circuit is configured to receive a cardiac electrical signal and sense a cardiac event in response to the signal crossing a cardiac event sensing threshold. The therapy delivery circuit is configured to deliver an electrical stimulation therapy to a patient's heart via the electrodes coupled to the implantable medical device. The control circuit is configured to control the sensing circuit to set a starting value of the cardiac event sensing threshold and hold the starting value constant for a sense delay interval. The control circuit is further configured to detect an arrhythmia based on cardiac events sensed by the sensing circuit and control the therapy delivery circuit to deliver the electrical stimulation therapy in response to detecting the arrhythmia.

公开(公告)号：US10213125B2

公开(公告)日：2019-02-26

申请号：US14604468

申请日：2015-01-23

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot

IPC: A61B5/0456 ,  A61B5/046 ,  A61B5/00 ,  A61B5/0452

Abstract: A method and medical device for detecting a cardiac event that includes sensing a cardiac signal, determining RR-intervals in response to the sensed cardiac signal, detecting a cardiac event in response to the RR-intervals, iteratively sensing a predetermined number of P-waves in response to detecting the cardiac event, and confirming the cardiac event in response to the iteratively sensed P-waves.

公开(公告)号：US09717437B2

公开(公告)日：2017-08-01

申请号：US14520798

申请日：2014-10-22

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J DeGroot

IPC: A61B5/046 ,  A61B5/0456 ,  A61B5/00 ,  A61N1/39

CPC classification number: A61B5/046 ,  A61B5/0456 ,  A61B5/686 ,  A61N1/3962

Abstract: A method and medical device for determining a cardiac event that includes sensing a cardiac signal, determining a predetermined number of sensed cardiac events in response to the sensed cardiac signal, determining a plurality of sensed event windows in response to the predetermined number of the sensed cardiac events, determining, for each of the plurality of sensed event windows, whether a number of paced events is less than a paced event threshold, determining whether intervals within the sensed event windows having a number of paced events less than the paced event threshold are greater than an interval threshold, determining an interval difference factor for each of the plurality of windows having intervals less than the interval threshold, and determining the cardiac event in response to the interval difference factors determined for each of the plurality of windows.

公开(公告)号：US09675261B2

公开(公告)日：2017-06-13

申请号：US15004202

申请日：2016-01-22

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J. Degroot

IPC: A61B5/04 ,  A61B5/00 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/0464 ,  A61N1/362 ,  A61N1/37 ,  A61N1/39

CPC classification number: A61B5/04012 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/686 ,  A61B5/7264 ,  A61B5/7282 ,  A61N1/3624 ,  A61N1/3702 ,  A61N1/3956 ,  A61N1/3987 ,  G06F19/00

Abstract: A method and medical device for detecting a cardiac event that includes sensing a cardiac signal, identifying R-waves in the cardiac signal attendant ventricular depolarizations, determining RR-intervals between successive R-waves in response to the sensed cardiac signal, detecting an atrial tachyarrhythmia based on an analysis of the RR-intervals, iteratively sensing groups of a predetermined number of P-waves attendant atrial depolarizations in response to detecting the atrial tachyarrhythmia, and confirming the atrial tachyarrhythmia based on an analysis of the iteratively sensed groups of P-waves.

公开(公告)号：US20250041591A1

公开(公告)日：2025-02-06

申请号：US18926382

申请日：2024-10-25

Applicant: Medtronic, Inc.

Inventor： Mark T. Marshall ,  Jian Cao ,  Melissa G.T. Christie ,  Paul J. DeGroot ,  Vladimir P. Nikolski ,  Amy E. Thompson-Nauman

IPC: A61N1/05 ,  A61N1/39

Abstract: Implantable medical electrical leads having electrodes arranged such that a defibrillation coil electrode and a pace/sense electrode(s) are concurrently positioned substantially over the ventricle when implanted as described. The leads include an elongated lead body having a distal portion and a proximal end, a connector at the proximal end of the lead body, a defibrillation electrode located along the distal portion of the lead body, wherein the defibrillation electrode includes a first electrode segment and a second electrode segment proximal to the first electrode segment by a distance. The leads may include at least one pace/sense electrode, which in some instances, is located between the first defibrillation electrode segment and the second defibrillation electrode segment.

公开(公告)号：US12128230B2

公开(公告)日：2024-10-29

申请号：US18062714

申请日：2022-12-07

Applicant: Medtronic, Inc.

Inventor： Mark T. Marshall ,  Jian Cao ,  Melissa G. T. Christie ,  Paul J. DeGroot ,  Vladimir P. Nikolski ,  Amy E. Thompson-Nauman

IPC: A61N1/39 ,  A61N1/05

CPC classification number: A61N1/05 ,  A61N1/0504 ,  A61N1/3918

Abstract: Implantable medical electrical leads having electrodes arranged such that a defibrillation coil electrode and a pace/sense electrode(s) are concurrently positioned substantially over the ventricle when implanted as described. The leads include an elongated lead body having a distal portion and a proximal end, a connector at the proximal end of the lead body, a defibrillation electrode located along the distal portion of the lead body, wherein the defibrillation electrode includes a first electrode segment and a second electrode segment proximal to the first electrode segment by a distance. The leads may include at least one pace/sense electrode, which in some instances, is located between the first defibrillation electrode segment and the second defibrillation electrode segment.