公开(公告)号：US20100190824A1

公开(公告)日：2010-07-29

申请号：US12452389

申请日：2008-06-24

Applicant: Prabhat Kumar ,  Anookh Mohanan ,  Navnath Argade ,  Chakradhar Hadole ,  Appaji Mandhare ,  Ramesh Gupta ,  Shailesh Deshpande ,  Prashant Jamadarkhana ,  Poonam Joshi

Inventor： Prabhat Kumar ,  Anookh Mohanan ,  Navnath Argade ,  Chakradhar Hadole ,  Appaji Mandhare ,  Ramesh Gupta ,  Shailesh Deshpande ,  Prashant Jamadarkhana ,  Poonam Joshi

IPC: A61K31/4545 ,  C07D211/68 ,  A61P25/28 ,  A61P25/08 ,  A61P9/10

CPC classification number: C07D401/06 ,  C07D211/74 ,  C07D409/06 ,  C07D413/06

Abstract: The present invention relates to novel compounds of formula (I) or (II), their pharmaceutically acceptable salts and their hydrates, solvates, stereoisomers, conformers, tautomers, polymorphs and prodrugs and also pharmaceutically acceptable compositions containing them Wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification. The compounds of the present invention are HSP inducers and by virtue of this effect, useful for the treatment of various diseases accompanying pathological stress. The present invention also relates to a process for the preparation of the said novel compounds. The invention also relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract translation: 本发明涉及式（I）或（II）的新化合物，其药学上可接受的盐及其水合物，溶剂合物，立体异构体，构象异构体，互变异构体，多晶型物和前药以及含有它们的药学上可接受的组合物。其中R1，R2，R3， R4，R5，R6和R7如说明书中所定义。 本发明的化合物是HSP诱导剂，并且由于这种效果，可用于治疗伴随病理应激的各种疾病。 本发明还涉及制备所述新化合物的方法。 本发明还涉及上述化合物在制备用作药物的药物中的用途。

公开(公告)号：US20100170830A1

公开(公告)日：2010-07-08

申请号：US12661353

申请日：2010-03-16

Applicant: Tahmid I. Mizan ,  Ramesh Gupta

Inventor： Tahmid I. Mizan ,  Ramesh Gupta

IPC: C10G75/04

CPC classification number: B01J19/002 ,  B01J8/0085 ,  B01J8/025 ,  B01J8/0453 ,  B01J2208/00707

Abstract: This invention relates to reactors with mitigation of fouling-related pressure buildup, the reactors having a reactor bed containing at least one catalyst layer through which reactants flow. The mitigation of fouling which occurs at the top of the reactor bed is accomplished by using at least one blowback ring located near the top of the reactor bed.

Abstract translation: 本发明涉及具有减轻结垢相关压力累积的反应器，该反应器具有反应器床，该反应器床含有至少一个催化剂层，反应物通过该催化剂层流动。 通过使用位于反应器床顶部附近的至少一个回吹环来实现在反应器床的顶部发生的减轻污染。

公开(公告)号：US20090090559A1

公开(公告)日：2009-04-09

申请号：US12252931

申请日：2008-10-16

Applicant: Richard S. Polizzotti ,  Dennis George Peiffer ,  Ramesh Gupta ,  Norman M. Pokutylowicz ,  Barbara Carstensen ,  Michael J. Luton ,  Paul Matthew Spiecker

Inventor： Richard S. Polizzotti ,  Dennis George Peiffer ,  Ramesh Gupta ,  Norman M. Pokutylowicz ,  Barbara Carstensen ,  Michael J. Luton ,  Paul Matthew Spiecker

IPC: C09K8/58

CPC classification number: C09K8/03 ,  B29C44/00 ,  E21B21/08 ,  Y10T428/1328 ,  Y10T428/2982

Abstract: A compressible object is described that may be utilized in drilling mud and with a drilling system to manage the density of the drilling mud. The compressible object includes a shell that encloses an interior region. The shell experiences less strain when the external pressure is about equal to the internal pressure than when the external pressure is above or below a predetermined compression interval of the compressible object includes a shell that encloses an interior region.

Abstract translation: 描述了一种可压缩物体，其可用于钻井泥浆和钻井系统以管理钻井泥浆的密度。 可压缩物体包括封闭内部区域的壳体。 当外部压力大约等于内部压力的外部压力高于或低于可压缩物体的预定压缩间隔时，壳体遇到较小的应变，包括包围内部区域的壳体。

公开(公告)号：US20090090558A1

公开(公告)日：2009-04-09

申请号：US12252927

申请日：2008-10-16

Applicant: Richard S. Polizzotti ,  Dennis George Peiffer ,  Ramesh Gupta ,  Norman M. Pokutylowicz ,  Barbara Carstensen ,  Michael J. Luton ,  Paul Matthew Spiecker

Inventor： Richard S. Polizzotti ,  Dennis George Peiffer ,  Ramesh Gupta ,  Norman M. Pokutylowicz ,  Barbara Carstensen ,  Michael J. Luton ,  Paul Matthew Spiecker

IPC: C09K8/02

CPC classification number: C09K8/03 ,  C09K2208/10 ,  E21B21/08 ,  Y10T428/1328 ,  Y10T428/2982

Abstract: A compressible object is described that may be utilized in drilling mud and with a drilling system to manage the density of the drilling mud. The compressible object includes a shell that encloses an interior region. Also, the compressible object has an internal pressure (i) greater than about 200 pounds per square inch at atmospheric pressure and (ii) selected for a predetermined external pressure, wherein external pressures that exceed the internal pressure reduce the volume of the compressible object and wherein the shell being designed to reduce localized strains of the compressible object during expansion and compression of the compressible object.

Abstract translation: 描述了一种可压缩物体，其可用于钻井泥浆和钻井系统以管理钻井泥浆的密度。 可压缩物体包括封闭内部区域的壳体。 此外，可压缩物体在大气压下具有大于约200磅/平方英寸的内部压力（i），并且（ii）选择预定的外部压力，其中超过内部压力的外部压力减小了可压缩物体的体积， 其中所述壳被设计成在所述可压缩物体的膨胀和压缩期间减小所述可压缩物体的局部应变。

公开(公告)号：US20070204974A1

公开(公告)日：2007-09-06

申请号：US11726687

申请日：2007-03-22

Applicant: Ramesh Gupta ,  Walter Weissman ,  George Walchuk ,  Randall Partridge

Inventor： Ramesh Gupta ,  Walter Weissman ,  George Walchuk ,  Randall Partridge

IPC: F28D15/00 ,  F02G5/00

CPC classification number: F28D15/02 ,  F28D15/06

Abstract: The present invention is a heat pipe having a specified volume of working fluid determined in relation to the interior volume of the heat pipe and a target temperature TT, to provide self-temperature regulation and pressure management. The heat pipe comprises at least a evaporator region and a condenser region having a known interior volume V and a mass of working fluid given by the relationship Mwf=Dwf at TT×V plus an amount of additional working fluid sufficient to have the rate of evaporation about equal to the rate of condensation for the particular heat pipe configuration.

Abstract translation: 本发明是一种热管，其具有相对于热管的内部容积确定的特定体积的工作流体和目标温度T T T以提供自我温度调节和压力管理。 热管至少包括一个蒸发器区域和一个具有已知内部体积V的凝结器区域，以及由<？in-line-formula description =“In-line Formulas”end =“lead”？ 在T T x X <？？tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail tail 加上足以使蒸发速率等于特定热管结构的冷凝速率的附加工作流体的量。

公开(公告)号：US20060156403A1

公开(公告)日：2006-07-13

申请号：US11033426

申请日：2005-01-10

Applicant: Steven Haeffele ,  Ramesh Gupta ,  Ananth Raman ,  Srikant Vissamsetti

Inventor： Steven Haeffele ,  Ramesh Gupta ,  Ananth Raman ,  Srikant Vissamsetti

IPC: G06F12/14

CPC classification number: H04L63/0218 ,  H04L63/0227 ,  H04L63/1408 ,  H04L63/1441 ,  H04L63/20

Abstract: A system, method and computer program product are provided including a router and a security sub-system coupled to the router. Such security sub-system includes a plurality of virtual firewalls, a plurality of virtual intrusion prevention systems (IPSs), and a plurality of virtual virus scanners. Further, each of the virtual firewalls, IPSs, and virus scanners is assigned to at least one of a plurality of user and is configured in a user-specific

Abstract translation: 提供了一种系统，方法和计算机程序产品，其包括路由器和耦合到路由器的安全子系统。 这种安全子系统包括多个虚拟防火墙，多个虚拟入侵防御系统（IPS）以及多个虚拟病毒扫描器。 此外，每个虚拟防火墙，IPS和病毒扫描器被分配给多个用户中的至少一个，并且被配置为用户特定的

公开(公告)号：US20060065577A1

公开(公告)日：2006-03-30

申请号：US11227802

申请日：2005-09-14

Applicant: Jeffrey Dysard ,  Zhigou Hou ,  Jonathan McConnachie ,  Andrzej Malek ,  Ramesh Gupta ,  William Lewis

Inventor： Jeffrey Dysard ,  Zhigou Hou ,  Jonathan McConnachie ,  Andrzej Malek ,  Ramesh Gupta ,  William Lewis

IPC: C10G29/04 ,  C10G67/00

CPC classification number: C10G45/02 ,  C10G19/073 ,  C10G29/04 ,  C10G65/04 ,  C10G67/10

Abstract: Refractory or hard sulfur found in a hydrocarbon stream containing refractory sulfur heterocycle compounds, particularly those exhibiting steric hindrance, is removed from the stream by contacting it with a sodium reagent comprising a sodium component, having free sodium, supported on a solid support component. If the hydrocarbon stream contains more labile or easy sulfur, then it is treated, typically by hydrodesulfurization, to remove at least most of the labile sulfur before it is contacted with the sodium reagent. This is useful for bringing the sulfur level of middle distillate fuel streams, such as diesel and jet fuel fractions, down to a level of less than about 10 wppm, employing conventional hydrodesulfurizing catalysts and conditions.

公开(公告)号：US06692545B2

公开(公告)日：2004-02-17

申请号：US09780079

申请日：2001-02-09

Applicant: Craig S. Gittleman ,  Ramesh Gupta

Inventor： Craig S. Gittleman ,  Ramesh Gupta

IPC: C10K302

CPC classification number: B01D53/06 ,  B01D53/047 ,  B01D53/864 ,  B01D2253/102 ,  B01D2253/104 ,  B01D2253/108 ,  B01D2253/112 ,  B01D2256/16 ,  B01D2257/502 ,  B01D2257/504 ,  B01D2259/40052 ,  B01D2259/40062 ,  B01D2259/41 ,  C01B3/16 ,  C01B3/48 ,  C01B3/56 ,  C01B2203/0205 ,  C01B2203/0283 ,  C01B2203/0425 ,  C01B2203/047 ,  C01B2203/0475 ,  C01B2203/0495 ,  C01B2203/066 ,  C01B2203/0811 ,  C01B2203/0822 ,  C01B2203/0827 ,  C01B2203/0883 ,  C01B2203/1005 ,  C01B2203/1047 ,  C01B2203/1082 ,  C01B2203/1223 ,  C01B2203/1229 ,  C01B2203/1241 ,  C01B2203/1247 ,  C01B2203/146 ,  C01B2203/1604 ,  C01B2203/1652 ,  C01B2203/82 ,  H01M8/0612 ,  H01M8/0668 ,  Y02C10/08 ,  Y02P20/128 ,  Y02P20/129 ,  Y02P20/152

Abstract: An apparatus removes CO from a hydrogen-rich gas stream in a hydrogen fuel cell system. CO fouls costly catalytic particles in the membrane electrode assemblies. Both a catalyst adapted to perform a water gas shift reaction, and a carbon dioxide adsorbent are disposed in a rotating pressure swing adsorber housing. The adsorption of carbon dioxide shifts equilibrium toward carbon monoxide consumption. A second adsorbent may be disposed in the housing for adsorbing carbon monoxide at low temperatures, and is adapted to desorb carbon monoxide at high temperatures. The present invention advantageously eliminates a unit operation from a space-constrained fuel cell vehicle by combining the WGS catalyst and a CO2 adsorbent in a single reactor/housing. The apparatus further eliminates the use of a PROX reactor, by providing an apparatus which incorporates CO2 adsorption and consequent carbon monoxide consumption in the place of the PROX reactor.

Abstract translation: 一种装置从氢燃料电池系统中的富氢气流中除去CO。 CO会损坏膜电极组件中昂贵的催化颗粒。 适用于执行水煤气变换反应的催化剂和二氧化碳吸附剂均设置在旋转变压吸附器壳体中。 二氧化碳的吸附将平衡转移到一氧化碳消耗。 第二吸附剂可以设置在壳体中用于在低温下吸附一氧化碳，并且适于在高温下解吸一氧化碳。 本发明通过在单个反应器/壳体中组合WGS催化剂和CO 2吸附剂有利地消除了来自空间受限的燃料电池车辆的单元操作。 该设备进一步消除了使用PROX反应器，通过提供一种将CO 2吸附和随后的一氧化碳消耗引入到PROX反应器的装置中。

公开(公告)号：US06623622B2

公开(公告)日：2003-09-23

申请号：US09960015

申请日：2001-09-21

Applicant: Ramesh Gupta

Inventor： Ramesh Gupta

IPC: C10G6502

CPC classification number: C10G65/08

Abstract: A diesel fraction is purified by a process having two reaction stages and a stripping stage in a single vessel. Heteroatoms are removed in the first stage, to permit the use of a sulfur sensitive aromatics saturation catalyst in the second stage, to produce a purified diesel stock. The first stage liquid effluent is stripped in a stripping stage and then passed into the second reaction stage, in which it reacts with fresh hydrogen for aromatics removal. The second reaction stage produces a hydrogen-rich vapor effluent, which may provide all or a portion of the first stage reaction hydrogen. A noble metal catalyst is employed in the second stage. The diesel feed for the process may be one that has been at least partially refined with respect to either or both heteroatom or aromatics removal.

公开(公告)号：US06593947B1

公开(公告)日：2003-07-15

申请号：US08646528

申请日：1996-05-10

Applicant: Dylan B. Ashe ,  Lewis Karl Cirne ,  Jeffrey Robert Cobb ,  Ramesh Gupta ,  Eric Charles Schlegel

Inventor： Dylan B. Ashe ,  Lewis Karl Cirne ,  Jeffrey Robert Cobb ,  Ramesh Gupta ,  Eric Charles Schlegel

IPC: G06F1721

CPC classification number: G06F9/451

Abstract: A system for providing polymorphic image data for images in a graphical user interface on a computer system includes an operating system, and an imaging object structure, the imaging object structure included in the operating system and utilized to generate images in the graphical user interface. Additionally, the imaging object structure further comprises a subclass of imaging objects, the subclasses includes singular imaging objects and composite imaging objects. The singular imaging objects further include, but are not limited to, text imaging objects, picture imaging objects, pattern imaging objects, and icon imaging objects. Additionally, the composite imaging objects generate composite images of a desired combination of singular images generated by the singular imaging objects. Further, the imaging object structure includes a SOM object structure.

Abstract translation: 用于在计算机系统上的图形用户界面中为图像提供多态图像数据的系统包括操作系统和成像对象结构，该成像对象结构包括在操作系统中并用于在图形用户界面中生成图像。 此外，成像对象结构还包括成像对象的子类，子类包括单个成像对象和复合成像对象。 单个成像对象还包括但不限于文本成像对象，图像成像对象，图案成像对象和图标成像对象。 此外，复合成像对象产生由单个成像对象产生的奇异图像的期望组合的合成图像。 此外，成像对象结构包括SOM对象结构。