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公开(公告)号:US20060234355A1
公开(公告)日:2006-10-19
申请号:US10464488
申请日:2003-06-19
申请人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
发明人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
CPC分类号: C12Y302/01158 , C12N9/2465 , C12P19/04 , C12P19/24
摘要: A polypeptide having an α-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
摘要翻译: 具有α-琼脂糖酶活性的多肽,编码该多肽的基因,通过遗传工程生产该多肽的方法以及使用该多肽制备琼脂低聚糖的方法。
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公开(公告)号:US06599729B2
公开(公告)日:2003-07-29
申请号:US09924097
申请日:2001-08-08
申请人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
发明人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
IPC分类号: C12N924
CPC分类号: C12Y302/01158 , C12N9/2465 , C12P19/04 , C12P19/24
摘要: A polypeptide having an &agr;-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
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公开(公告)号:US07678368B2
公开(公告)日:2010-03-16
申请号:US11311341
申请日:2005-12-20
申请人: Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人: Shigetoshi Mizutani , Suzu Deguchi , Eiji Kobayashi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
CPC分类号: A61Q19/10 , A61K8/60 , A61K8/73 , A61K8/9706 , A61K31/04 , A61K31/08 , A61K31/13 , A61K31/70 , A61K33/20 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00 , A61Q19/005 , A61Q19/007 , A61Q19/08 , Y10S514/88
摘要: To find a substance which has a skin cosmeticizing effect such as prevention of skin aging, amelioriation of sensitive skin, or antipruritic action, and can serve as an effective ingredient for a hair-care product, thereby providing cosmetics comprising the effective ingredient. Concretely, there are provided cosmetics characterized in that the cosmetics comprise as an effective ingredient a compound selected from a fucoidan, a degradation product thereof, a sulfated monosaccharide or a salt thereof.
摘要翻译: 为了找到具有防止皮肤老化,敏感性皮肤的改善或止痒作用的皮肤美容效果的物质,可以作为护发品的有效成分,从而提供含有效成分的化妆品。 具体地,提供了化妆品,其特征在于,所述化妆品包含选自岩藻依聚糖,其降解产物,硫酸化单糖或其盐的化合物作为有效成分。
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公开(公告)号:US20050124575A1
公开(公告)日:2005-06-09
申请号:US10507937
申请日:2003-04-14
申请人: Eiji Nishiyama , Nobuko Muraki , Hiromu Ohnogi , Hiroaki Sagawa , Ikunoshin Kato
发明人: Eiji Nishiyama , Nobuko Muraki , Hiromu Ohnogi , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号: A23K1/16 , A23L1/0532 , A23L1/30 , A61K31/715 , A61K31/729 , A61P29/00 , C08B37/00 , A23G3/00 , A61K47/00
CPC分类号: C08B37/0039 , A23K20/163 , A23L29/256 , A23L33/10 , A23V2002/00 , A61K31/715 , A61K31/729 , A23V2250/5024 , A23V2250/1578 , A23V2250/5108 , A23V2250/616 , A23V2250/5118
摘要: Remedies or preventives, which are characterized by containing as the active ingredient at least one member selected from the group consisting of agar, agarose, high-molecular weight digestion products originating in agar and high-molecular weight digestion products originating in agarose, for diseases sensitive to the above active ingredients.
摘要翻译: 其特征在于含有选自琼脂,琼脂糖,源自琼脂的高分子量消化产物和起源于琼脂糖的高分子量消化产物中的至少一种成分为活性成分,用于疾病敏感性的补救剂或预防剂 以上活性成分。
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公开(公告)号:US07410786B2
公开(公告)日:2008-08-12
申请号:US11681453
申请日:2007-03-02
申请人: Harumi Ueno , Jun Tomono , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
发明人: Harumi Ueno , Jun Tomono , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
CPC分类号: C12N9/2465 , C12N9/2402 , C12P19/00 , C12P19/04 , C12P19/12 , C12P19/14 , G01N2333/924
摘要: A gene encoding a polypeptide having an activity of digesting sulfated fucogalactan which is useful in sugar chain engineering reagents, analyzing the structures of sulfated fucose-containing polysaccharides and preparing degraded products of the polysaccharides; a genetic engineering process for producing the polypeptide; and the polypeptide obtained by the process.
摘要翻译: 编码具有消化硫酸化的赖氨酰半乳糖的活性的多肽的基因,其可用于糖链工程试剂,分析硫酸化岩藻糖多糖的结构并制备多糖的降解产物; 用于产生多肽的基因工程方法; 和通过该方法获得的多肽。
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公开(公告)号:US07329524B2
公开(公告)日:2008-02-12
申请号:US10467824
申请日:2002-02-26
申请人: Jun Tomono , Hiroaki Sagawa , Ikunoshin Kato
发明人: Jun Tomono , Hiroaki Sagawa , Ikunoshin Kato
CPC分类号: C12Y302/01081 , C12N9/2468
摘要: Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide; a process for producing the polypeptide; a process for producing agaro-oligosaccharide; and a process for extracting a substance such as a nucleic acid from an agarose gel.
摘要翻译: 高效生产琼脂寡糖的生产; 具有琼脂糖酶活性的多肽,其可用于例如从琼脂糖凝胶中有效地提取诸如核酸的物质; 多肽的氨基酸序列; 编码该多肽的基因; 一种生产该多肽的方法; 制备琼脂寡糖的方法; 以及从琼脂糖凝胶中提取核酸等物质的方法。
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公开(公告)号:US20070166804A1
公开(公告)日:2007-07-19
申请号:US11553912
申请日:2006-10-27
申请人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
发明人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
CPC分类号: C12Y302/01158 , C12N9/2465 , C12P19/04 , C12P19/24
摘要: A polypeptide having an α-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
摘要翻译: 具有α-琼脂糖酶活性的多肽,编码该多肽的基因,通过遗传工程生产该多肽的方法以及使用该多肽制备琼脂低聚糖的方法。
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公开(公告)号:US07244588B2
公开(公告)日:2007-07-17
申请号:US10538793
申请日:2003-12-11
申请人: Jun Tomono , Harumi Ueno , Masayuni Kishimoto , Hiroaki Sagawa , Ikunoshin Kato
发明人: Jun Tomono , Harumi Ueno , Masayuni Kishimoto , Hiroaki Sagawa , Ikunoshin Kato
摘要: A vector having a region encoding a cold shock protein gene mRNA-origin 5′-nontranslated region, characterized in that the 5′-nontranslated region has a mutation having been transferred therein so as to change the distance of the stem structure formed by the region.
摘要翻译: 具有编码冷激蛋白基因mRNA起始的5'-非翻译区的区域的载体,其特征在于,所述5'-非翻译区具有转移的突变,以便改变由所述区域形成的茎结构的距离 。
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公开(公告)号:US07141402B2
公开(公告)日:2006-11-28
申请号:US10464488
申请日:2003-06-19
申请人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
发明人: Jun Tomono , Yoshiko Nomura , Hiroaki Sagawa , Takeshi Sakai , Ikunoshin Kato
CPC分类号: C12Y302/01158 , C12N9/2465 , C12P19/04 , C12P19/24
摘要: A polypeptide having an α-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
摘要翻译: 具有α-琼脂糖酶活性的多肽,编码该多肽的基因,通过遗传工程生产该多肽的方法以及使用该多肽制备琼脂低聚糖的方法。
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公开(公告)号:US07268160B2
公开(公告)日:2007-09-11
申请号:US10182193
申请日:2001-01-26
申请人: Hiromu Ohnogi , Masahiro Shiraga , Eiji Kobayashi , Tuo-Ping Li , Suzu Deguchi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人: Hiromu Ohnogi , Masahiro Shiraga , Eiji Kobayashi , Tuo-Ping Li , Suzu Deguchi , Eiji Nishiyama , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号: A61K31/35 , A61K31/22 , C07D307/02 , C07C67/02
CPC分类号: A61K31/7004 , A23L33/10 , A61K31/12 , A61K31/216 , A61K31/222 , A61K31/352
摘要: The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production, each comprising as an effective ingredient a specified compound or a salt thereof having enhancing activity for nerve growth factor production; a method for enhancing nerve growth factor production, comprising administering to a mammal the above-mentioned compound or a salt thereof; and use of the above-mentioned compound or a salt thereof in the preparation of a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production. In addition, the present invention provides novel compounds having enhancing activity for nerve growth factor production.
摘要翻译: 本发明提供了需要增强神经生长因子产生的疾病的治疗剂或预防剂,用于神经生长因子产生的增强剂或用于增强神经生长因子产生的食品,饮料或饲料,其各自包含作为有效成分 具有增强神经生长因子生成活性的特定化合物或其盐; 一种用于增强神经生长因子产生的方法,包括向哺乳动物施用上述化合物或其盐; 以及上述化合物或其盐在制备需要增强神经生长因子产生的疾病的治疗剂或预防剂,用于神经生长因子产生的增强剂或食品,饮料或饲料中的用途 增强神经生长因子的产生。 此外,本发明提供了具有增强神经生长因子产生活性的新型化合物。
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