摘要:
The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors encoding the same, and recombinant T cells comprising the CD33 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD33 binding domain.
摘要:
A locking element is described for securing containers, pallets or similar freight items in the cargo bay of an aircraft, wherein a first and a second locking claw are mounted on a frame swivellable from a lowered loading position into a raised working position for securing containers. A remotely controllable adjustment device is provided to change and adjust the state of the locking claws between the loading state in which the locking claws are in the loading position, a holding state in which the locking claws are in the working position and fixed, and a trigger state in which the locking claws are in the working position but can be swivelled from the working position into the loading position if a force acting on the locking claws exceeds a predetermined amount.
摘要:
A device for detecting at least one substance of a fluid, has a piezoacoustic thin film resonator with a piezoelectric layer on which electrode layers are arranged, and an adsorption surface for adsorbing the fluid substance, wherein the piezoelectric and electrode layers and the adsorption surface are designed and arranged on each other such that by electrically activating the electrode layers, an excitation alternating field can be coupled into the piezoelectric layer. The thin film resonator can be excited to a resonance oscillation frequency fR which depends on an amount of the substance adsorbed on the adsorption surface because of an excitation alternating field coupled into the piezoelectric layer. An electrical insulating layer is arranged directly on a side of one of the electrode layers facing away from the piezoelectric layer. Particularly advantageous is the combination of an aluminum electrode layer and a silicon dioxide insulating layer.
摘要:
Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly obtaining a NABB not associated with membrane proteins. Immunogenic compositions comprising NABBs with native conformational epitopes are also provided along with their methods of use.
摘要:
The invention relates to a cargo holding device, in particular cargo container or pallet, for loading aircraft, comprising a bottom element and a plurality of profile elements and corner elements, wherein a bottom element edge portion is connected to the profile elements and corner elements, wherein the profile elements are connected to the corner elements via push-fit connections, wherein at least one profile element is connected to at least one corner element via a push-fit connection which comprises a push-fit connection recess and a corresponding push-fit connection pin, wherein the push-fit connection recess and the push-fit connection pin are configured such that the profile element and the corner element can be connected together by push-fit by a translational movement, wherein a translational movement direction has an angle in relation to a profile longitudinal axis of the profile element.
摘要:
To secure containers in a cargo bay of an aircraft, locking elements are known comprising locking lugs which can move from a locked position to a rest position. The locking lugs engage in engagement recesses of freight items. On movement of the locking lugs from the locked position to the rest position, the locking lugs can seize in the engagement recesses. A locking element is proposed to which a pair of locking lugs is allocated which in the locked position each have a stop surface which can be brought into engagement on a stop edge of the engagement recess, wherein the locking lugs are mounted mobile such that on movement from the locked position to a rest position, the two stop surfaces separate from the stop edges. As a result the space required in the holding direction for the locking lugs and the risk of seizing of the locking lugs in the engagement recess are substantially reduced.
摘要:
A cargo hold floor of an upper and/or a lower deck of an aircraft having a plane of symmetry which divides the cargo hold floor into a first half and a second half is disclosed, said cargo hold floor comprising locking gaps which each encompass all the locking elements located substantially on one level in the longitudinal direction (x direction) of the aircraft, in particular longitudinal locking elements for securing standardized cargo containers, in particular pallets and/or containers, in the longitudinal direction (x direction) of the aircraft whereby all the longitudinal locking elements of at least one locking gap are arranged in only one of the halves.
摘要:
In the present digital age, the storage of data and the administration of the stored data is a problem area which, despite rapidly dropping prices for storage media, is increasingly important as technology becomes more sophisticated. In the field of security technology, for instance, storing streams of video data or compressed streams of video data that are recorded by surveillance cameras plays an important role. Some of the streams of video data stored should be stored for a defined length of time, such as a few days, while some data should be stored permanently, and there is accordingly a need for a highly flexible solution to the problem. A video recording system for recording video data, a method for memory space distribution in the video recording system, and a computer program for this purpose are proposed.
摘要:
A floor module with roller conveyors which define an aircraft cargo hold floor with a loading level is provided. The floor modules have cross-members to which the roller conveyor is attached. A rail with two side pieces is provided, between which rollers are rotatably mounted in such a way that they protrude above upper edges of the rails. The side pieces are joined to one another by a floor section. To improve the strength of the floor module, the floor section has a bent region inclined in cross-section at an angle to the loading level, the bent region dividing the floor section into one partial section lying higher and one partial section lying lower relative to the upper edges.