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公开(公告)号：US20220002342A1
公开(公告)日：2022-01-06
申请号：US17469102
申请日：2021-09-08
发明人： David MACMILLAN , Daniel Novoa , Stefan McCarver
摘要： Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.
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公开(公告)号：US20210406668A1
公开(公告)日：2021-12-30
申请号：US17360155
申请日：2021-06-28
摘要： A hybrid neuromorphic computing device is provided, in which artificial neurons include light-emitting devices that provide weighted sums of inputs as light output. The output is detected by a photodetector and converted to an electrical output. Each neuron may receive output from one or more other neurons as initial input. Interconnects between neurons may be optical, electrical, or a combination thereof. The neurons also may provide imaging sensor and/or display capabilities.
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公开(公告)号：US20210380952A1
公开(公告)日：2021-12-09
申请号：US17381930
申请日：2021-07-21
发明人： Emre Koyuncu , Ileana M. Cristea , Thomas Shenk
摘要： A method is provided to improve virus production is an infected host cell by culturing the infected cell in an effective amount of alpha-ketoglutarate.
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公开(公告)号：US11187963B2
公开(公告)日：2021-11-30
申请号：US16775746
申请日：2020-01-29
发明人： Chaoran Huang , Thomas Ferreira De Lima , Alexander Tait , Siamak Abbaslou , Aashu Jha , Bhavin Shastri , Paul R. Prucnal , Mitchell A. Nahmias , Hsuan-Tung Peng
摘要： According to various embodiments, an all-optical thresholder device is disclosed. The all-optical thresholder device includes a Mach-Zehnder interferometer (MZI) coupled to a Mach-Zehnder coupler (MZC). The MZI includes at least one microring resonator (MRR) and a first tunable element, where the MRR further includes a second tunable element. The MZC includes a third tunable element. The first, second, and third tunable elements are configured to control biases of the all-optical thresholder device to achieve a desired power transfer function.
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公开(公告)号：US20210367065A1
公开(公告)日：2021-11-25
申请号：US17389117
申请日：2021-07-29
发明人： Jason Petta , Xiao Mi , David Zajac
IPC分类号： H01L29/66
摘要： Methods, devices, and systems are described for storing and transferring quantum information. An example device may comprise at least one semiconducting layer, one or more conducting layers configured to define at least two quantum states in the at least one semiconducting layer and confine an electron in or more of the at least two quantum states, and a magnetic field source configured to generate an inhomogeneous magnetic field. The inhomogeneous magnetic field may cause a first coupling of an electric charge state of the electron and a spin state of the electron. The device may comprise a resonator configured to confine a photon. An electric-dipole interaction may cause a second coupling of an electric charge state of the electron to an electric field of the photon.
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公开(公告)号：US11161147B2
公开(公告)日：2021-11-02
申请号：US16270787
申请日：2019-02-08
发明人： Johan A. Carlsson
摘要： According to various embodiments, a system for acoustic to electronic transduction is disclosed. The system includes a transducing medium configured to convert a received acoustic signal into a transduced electronic signal when a voltage is applied. The system further includes a high-pass filter coupled to the transducing medium, the high-pass filter configured to isolate the transduced signal from the applied voltage.
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公开(公告)号：US20210330287A1
公开(公告)日：2021-10-28
申请号：US17232642
申请日：2021-04-16
摘要： This disclosure describes systems and methods for crosstalk-free source encoding for ultrasound tomography. This disclosed systems and methods feature real data acquisition acceleration and/or numerical simulation acceleration (or image processing acceleration).
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公开(公告)号：US11154667B2
公开(公告)日：2021-10-26
申请号：US16096901
申请日：2017-04-27
发明人： Joshua Rabinowitz
摘要： The present invention an electronic inhaler for the delivery of pharmaceuticals through vaporization.
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公开(公告)号：US20210290675A1
公开(公告)日：2021-09-23
申请号：US17258716
申请日：2019-07-11
申请人： GPB SCIENTIFIC, INC. , THE TRUSTEES OF PRINCETON UNIVERSITY , UNIVERSITY OF MARYLAND, BALTIMORE
发明人： Anthony WARD , Roberto CAMPOS-GONZALEZ , Alison SKELLEY , Khushroo GANDHI , Michael GRISHAM , Curt CIVIN , James C. STURM
摘要： The present invention is directed to the use of microfluidics in the preparation of genetically transformed cells and compositions for therapeutic uses.
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公开(公告)号：US11121239B2
公开(公告)日：2021-09-14
申请号：US16534431
申请日：2019-08-07
发明人： Jason Petta , Xiao Mi , David Zajac
IPC分类号： H01L29/66
摘要： Methods, devices, and systems are described for storing and transferring quantum information. An example device may comprise at least one semiconducting layer, one or more conducting layers configured to define at least two quantum states in the at least one semiconducting layer and confine an electron in or more of the at least two quantum states, and a magnetic field source configured to generate an inhomogeneous magnetic field. The inhomogeneous magnetic field may cause a first coupling of an electric charge state of the electron and a spin state of the electron. The device may comprise a resonator configured to confine a photon. An electric-dipole interaction may cause a second coupling of an electric charge state of the electron to an electric field of the photon.
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