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    INFORMATION RETRIEVAL SYSTEM AND METHOD USING A BAYESIAN ALGORITHM BASED ON PROBABILISTIC SIMILARITY SCORES
    62.
    发明申请
    INFORMATION RETRIEVAL SYSTEM AND METHOD USING A BAYESIAN ALGORITHM BASED ON PROBABILISTIC SIMILARITY SCORES 审中-公开
    信息检索系统和使用基于概率相似性的贝叶斯算法的方法

    公开(公告)号：US20100223258A1

    公开(公告)日：2010-09-02

    申请号：US12095637

    申请日：2006-12-01

    申请人： Zoubin Ghahramani ,  Katherine Anne Heller

    发明人： Zoubin Ghahramani ,  Katherine Anne Heller

    IPC分类号： G06F17/30

    CPC分类号： G06K9/6278 ,  G06F16/3346 ,  G06F16/583 ,  G06F16/951

    摘要： An algorithm is provided which uses a model-based concept of a cluster and scores items using a score representative of the probability that a given item has been generated from the same distribution as one or more query items. The items are represented by a feature vector xi comprising a plurality of digitally represented features xij the method including: receiving an input identifying the query items; for each of the other items computing a score which is a function of a conditional probability of the feature vectors xij of the query items being generated from the generating distribution formula (I) given that the respective other item is generated from the generating distribution formula (I) and returning a score for each of the other items, a list of some or all of the other items, sorted by their respective score, or a list of n other items which have the highest score.

    摘要翻译： 提供了一种算法，其使用群集的基于模型的概念，并且使用表示从与一个或多个查询项目相同的分布生成给定项目的概率的分数来评分项目。 这些项目由包括多个数字表示的特征的特征向量xi表示，该方法包括：接收标识查询项目的输入; 对于每个其他项目，计算作为从生成分配公式（I）生成的查询项目的特征向量xij的条件概率的函数的分数，假设从生成分配公式生成了相应的其他项目 I）并返回每个其他项目的分数，按其各自分数排序的一些或所有其他项目的列表，或者具有最高分数的n个其他项目的列表。

    BIOMATERIAL SCAFFOLDS FOR CONTROLLED TISSUE GROWTH
    63.
    发明申请
    BIOMATERIAL SCAFFOLDS FOR CONTROLLED TISSUE GROWTH 审中-公开
    用于控制组织生长的生物材料SCAFFOL

    公开(公告)号：US20100168872A1

    公开(公告)日：2010-07-01

    申请号：US12676342

    申请日：2008-09-03

    申请人： Robert BROWN ,  Tijna ALEKSEEVA

    发明人： Robert BROWN ,  Tijna ALEKSEEVA

    IPC分类号： A61F2/02 ,  C12N5/07

    CPC分类号： A61L27/58 ,  A61L27/24 ,  A61L27/38 ,  A61L27/50 ,  A61L27/52 ,  A61L27/56

    摘要： This invention relates to biomaterials for directional tissue growth which comprise soluble fibres having a variable cross-sectional area which dissolve in a directional manner in situ, thereby controlling the direction and rate of formation of microchannels within the biomaterial and allowing vectored and timed channelling through the biomaterial. This may be useful, for example in directing the growth of blood vessels, nerves and other repair cells through the biomaterial in defined directions.

    摘要翻译： 本发明涉及用于定向组织生长的生物材料，其包含具有可变横截面积的可溶性纤维，其可以以原位方向的方式溶解，从而控制生物材料内微通道的形成方向和速率，并允许通过 生物材料。 这可能是有用的，例如在指定方向上通过生物材料引导血管，神经和其他修复细胞的生长。

    Methods of diagnosing bladder cancer
    66.
    发明授权
    Methods of diagnosing bladder cancer 有权

    公开(公告)号：US11473148B2

    公开(公告)日：2022-10-18

    申请号：US15738539

    申请日：2016-06-24

    申请人： UCL Business PLC

    发明人： Andrew Feber ,  John Kelly

    IPC分类号： C12Q1/6886 ,  C12Q1/686 ,  C12Q1/6827 ,  C12Q1/6858 ,  G01N33/574

    摘要： The present invention relates to methods of diagnosing bladder cancer in a patient, involving determining the methylation status of Methylation Variable Positions (MVPs) in DNA from the patient and providing a diagnosis based on methylation status data. The invention also relates to methods of treating bladder cancer comprising providing a diagnosis of bladder cancer by the diagnostic methods defined herein followed by administering one or more anti-cancer agents to a patient. The invention also relates to methylation-discriminatory arrays comprising probes directed to the MVPs defined herein and kits comprising the arrays.