公开(公告)号：US20160131627A1

公开(公告)日：2016-05-12

申请号：US14896785

申请日：2014-05-20

Applicant: DRÄGER SAFETY AG & CO. KGAA

Inventor： Hans-Ullrich HANSMANN ,  Philipp ROSTALSKI

IPC: G01N33/00 ,  G01F1/708 ,  G01F1/66

CPC classification number: G01N33/0067 ,  G01F1/661 ,  G01F1/704 ,  G01F1/7086 ,  G01F1/74 ,  G01N21/77 ,  G01N21/85 ,  G01N31/223 ,  G01N33/007 ,  G01N2015/0026 ,  G01P5/001 ,  G01P5/20

Abstract: A measuring system (10) and method measure a concentration of components of a gas mixture of gas/aerosol. A reaction support (14) has a flow channel (42) that forms a reaction chamber (46) with an optically detectable reactant (48) that reacts with at least one component or with a reaction product of the component. The flow channel (42) is at least partially filled with particles (100, 102, 104, 110) which have a pre-flow starting position and to which a gas flow is applied through the flow channel (42) in a flow position. The particles (100, 102, 104, 110) are designed (configured) in such a manner that the particles (100, 102, 104, 110) in the starting position and the particles (100, 102, 104, 110) in the flow position can be optically distinguished. The invention also relates to an optical flow sensor (109) for determining a flow of a fluid.

Abstract translation: 测量系统（10）和方法测量气体/气溶胶气体混合物的组分浓度。 反应载体（14）具有流动通道（42），其形成具有与至少一种组分或组分的反应产物反应的可光学检测的反应物（48）的反应室（46）。 流动通道（42）至少部分地填充有具有预流起始位置的颗粒（100,102,104,110），并且在流动位置通过流动通道（42）施加气流。 颗粒（100,102,104,110）被设计（配置），使得处于起始位置的颗粒（100,102,104,110）和颗粒（100,102,104,110）中的颗粒 流动位置可以光学地区分。 本发明还涉及一种用于确定流体流动的光学流量传感器（109）。

公开(公告)号：US20160025535A1

公开(公告)日：2016-01-28

申请号：US14774921

申请日：2014-03-14

Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH

Inventor： Charles L. Byers ,  Chris J. Hetlinger

IPC: G01F1/56

CPC classification number: G01F1/56 ,  G01F1/7086 ,  G01F1/7088

Abstract: A microfluidic flow rate sensor includes a droplet within a channel and a droplet movement detector that generates a signal based on the position and/or movement of the droplet within the channel. A processor determines the flow rate of a fluid through the channel based on the signal received from the droplet movement detector. In one example, the droplet movement detector is an optical detector, such as a combination of a lens and an image capturing device. In other examples, the droplet is electrically conductive, and at least a portion of the channel is conductive or includes electrical contacts. The position of the droplet within the channel is determined by observing the electrical characteristics of the channel.

Abstract translation: 微流体流量传感器包括通道内的液滴和液滴移动检测器，其基于通道内液滴的位置和/或移动产生信号。 处理器基于从液滴移动检测器接收的信号确定通过通道的流体的流速。 在一个示例中，液滴移动检测器是诸如透镜和图像捕获装置的组合的光学检测器。 在其他示例中，液滴是导电的，并且通道的至少一部分是导电的或包括电接触。 通过观察通道的电气特性来确定液滴在通道内的位置。

公开(公告)号：US09165357B2

公开(公告)日：2015-10-20

申请号：US13804248

申请日：2013-03-14

Applicant: Alverix, Inc.

Inventor： Scott Dylewski

IPC: G01F1/708 ,  G06T7/00 ,  G01N21/84 ,  G01N21/78

CPC classification number: G06T7/0012 ,  G01F1/7086 ,  G01N21/78 ,  G01N21/8483

Abstract: The present disclosure relates to methods for determining a wavefront position of a liquid on a surface of an assay test strip placing a liquid on the surface of the test strip; and acquiring one or more signals from the surface of the test strip at one or more times, comparing the one or more acquired signals to a threshold, wherein the wavefront position is a position on the surface of the test strip where a signal is greater than or less than a threshold (e.g., fixed or dynamic threshold). Such methods may be used to determine the wavefront velocity of a liquid on a surface of an assay test strip and the transit time of a liquid sample to traverse the one or more positions on the surface of the assay test strip.

Abstract translation: 本公开涉及用于确定在测试条的表面上放置液体的测定试纸的表面上的液体的波前位置的方法; 以及一次或多次从所述测试条的表面获取一个或多个信号，将所述一个或多个获取的信号与阈值进行比较，其中所述波前位置是所述测试条的表面上的位置，其中信号大于 或小于阈值（例如，固定或动态阈值）。 这样的方法可以用于确定测定试纸的表面上的液体的波前速度和液体样品穿过测定测试条的表面上的一个或多个位置的通过时间。

公开(公告)号：US20150149099A1

公开(公告)日：2015-05-28

申请号：US14549860

申请日：2014-11-21

Applicant: Fluke Electronics Corporation

Inventor： Malcolm Charles Brown ,  Keith Norman McMann

IPC: G01F1/708

CPC classification number: G01F1/7086 ,  G01F1/007 ,  G01F23/292

Abstract: A flow measuring device, comprising a container for receiving a flow of liquid, a plurality of optical sensors associated with the container, each of the plurality of optical sensors producing an output signal dependent upon the presence of liquid reaching a level in the container associated with each optical sensor, means for modifying the output signal in accordance with at least one predetermined temperature compensation factor, and means for calculating a flow rate from the time at which the liquid traverses between two levels in the container.

Abstract translation: 一种流量测量装置，包括用于接收液体流的容器，与所述容器相关联的多个光学传感器，所述多个光学传感器中的每一个光学传感器产生输出信号，所述输出信号取决于液体的存在达到与所述容器相关联的容器中的水平 每个光学传感器，用于根据至少一个预定温度补偿因子来修改输出信号的装置，以及用于从液体在容器中的两个水平面之间穿过的时间计算流量的装置。

公开(公告)号：US20140324366A1

公开(公告)日：2014-10-30

申请号：US14328198

申请日：2014-07-10

Applicant: Halliburton Energy Services, Inc.

Inventor： Patrick Matthew Ljungdahl ,  Sean A. Roach ,  Alexis Wachtel

IPC: G01F1/66 ,  E21B49/08

CPC classification number: G01F1/661 ,  E21B21/067 ,  E21B47/00 ,  E21B49/005 ,  E21B49/08 ,  G01F1/7086 ,  G01F1/74 ,  G01F1/86 ,  G01N21/31

Abstract: An example system includes a separator that accepts and separates a multiphase flowback effluent stream into a plurality of secondary streams. A first sensor assembly monitors the multiphase flowback effluent stream and generates a first signal corresponding to at least one characteristic of the multiphase flowback effluent stream. A second sensor assembly monitors one of the plurality of secondary streams and generates a second signal corresponding to at least one characteristic of the one of the plurality of secondary streams. A signal processor receives the first and second signals and determines a mass flow rate of a substance present in both the multiphase flowback effluent stream and the one of the plurality of secondary streams.

Abstract translation: 示例系统包括分离器，其将多相回流流出物流接收并分离成多个次流。 第一传感器组件监测多相回流流出物流并产生对应于多相回流流出物流的至少一个特性的第一信号。 第二传感器组件监测多个次流中的一个，并且产生对应于多个次流中的一个的至少一个特性的第二信号。 信号处理器接收第一和第二信号并且确定存在于多相回流流出物流和多个次流中的一个的物质的质量流量。

公开(公告)号：US20140272984A1

公开(公告)日：2014-09-18

申请号：US13836301

申请日：2013-03-15

Applicant: CANON U.S. LIFE SCIENCES, INC.

Inventor： Kenton C. Hasson ,  Gregory A. Dale

IPC: C12Q1/68

CPC classification number: B01L3/502746 ,  B01L3/502715 ,  B01L7/525 ,  B01L2200/143 ,  B01L2300/0627 ,  B01L2300/0816 ,  C12P19/34 ,  C12Q1/686 ,  G01F1/704 ,  G01F1/7086 ,  G01F1/712 ,  G05D7/00 ,  C12Q2565/629

Abstract: The present invention relates to systems and methods of monitoring velocity or flow in channels, especially in microfluidic channels. In some embodiments, the present invention relates to systems and methods of monitoring velocity or flow rate in systems and methods for performing a real-time polymerase chain reaction (PCR) in a continuous-flow microfluidic system.

Abstract translation: 本发明涉及监测通道，特别是微流体通道中的速度或流速的系统和方法。 在一些实施方案中，本发明涉及用于在连续流微流体系统中进行实时聚合酶链式反应（PCR）的系统和方法中监测速度或流速的系统和方法。

公开(公告)号：US08743350B2

公开(公告)日：2014-06-03

申请号：US13382104

申请日：2010-07-01

Applicant: Jean-Pierre Delville ,  Joël Plantard ,  Sébastien Cassagnere ,  Matthieu Robert de Saint Vincent

Inventor： Jean-Pierre Delville ,  Joël Plantard ,  Sébastien Cassagnere ,  Matthieu Robert de Saint Vincent

IPC: G01P3/36

CPC classification number: G01F1/74 ,  B01L3/502784 ,  G01F1/7086

Abstract: The invention relates to a device (1) for characterizing a two-phase flow in a channel (11), and to a related method. The device includes: a light source (10) for illuminating the channel (11), in which a fluid can flow in the form of a series of droplets in another fluid; a means (12) for detecting variations in illumination related to the passage of a drop in the channel, said detection means including at least two photodiodes (121, 122) arranged in series in the direction of the longitudinal axis of the channel (11), so that a droplet in said series of droplet flowing in the channel (11) can consecutively vary the illumination detected by the first photodiode (121) and then the illumination detected by the second photodiode (122), the photodiodes (121, 122) being reversibly mounted such that the difference in current between the electric currents of each of the two photodiodes can be determined in order to obtain a differential current representing the difference in the variation in the illumination of the photodiodes; and a processing means (19) for processing the data from the detection means (12) in order to provide data which are characteristic of the two-phase flow.

Abstract translation: 本发明涉及用于表征通道（11）中的两相流的装置（1）以及相关方法。 该装置包括：用于照亮通道（11）的光源（10），其中流体可以在另一流体中以一系列液滴的形式流动; 用于检测与通道中液滴通过有关的照明变化的装置（12），所述检测装置包括在通道（11）的纵向轴线方向上串联设置的至少两个光电二极管（121,122） ，使得在所述通道（11）中流动的所述一系列液滴中的液滴可以连续地改变由第一光电二极管（121）检测到的照明，然后连续地改变由第二光电二极管（122）检测的照明，光电二极管（121,122） 可逆地安装，使得可以确定两个光电二极管中的每一个的电流之间的电流差，以便获得表示光电二极管的照明变化的差异的差动电流; 以及用于处理来自检测装置（12）的数据的处理装置（19），以提供作为两相流的特征的数据。

公开(公告)号：US20130196345A1

公开(公告)日：2013-08-01

申请号：US13804284

申请日：2013-03-14

Applicant: Alverix, Inc.

Inventor： Scott Dylewski

IPC: G01N21/78

CPC classification number: G06T7/0012 ,  G01F1/7086 ,  G01N21/78 ,  G01N21/8483

Abstract: The present disclosure relates to methods for determining a wavefront position of a liquid on a surface of an assay test strip placing a liquid on the surface of the test strip; and acquiring one or more signals from the surface of the test strip at one or more times, comparing the one or more acquired signals to a threshold, wherein the wavefront position is a position on the surface of the test strip where a signal is greater than or less than a threshold (e.g., fixed or dynamic threshold). Such methods may be used to determine the wavefront velocity of a liquid on a surface of an assay test strip and the transit time of a liquid sample to traverse the one or more positions on the surface of the assay test strip.

公开(公告)号：US08429984B2

公开(公告)日：2013-04-30

申请号：US12737992

申请日：2009-09-17

Applicant: Noriaki Furusato ,  Yasumasa Honda ,  Daisuke Takahashi ,  Minoru Kotaki ,  Yoshikazu Hirano

Inventor： Noriaki Furusato ,  Yasumasa Honda ,  Daisuke Takahashi ,  Minoru Kotaki ,  Yoshikazu Hirano

IPC: G01F1/74

CPC classification number: G01N35/08 ,  G01F1/704 ,  G01F1/7086 ,  G01N33/49

Abstract: The present invention relates to a flow rate sensor 52 which causes a gas 80 included in a liquid 81 to travel in a piping 56, and which measures a flow speed of a sample by detecting the gas 80. The flow rate sensor 52 is configured to maintain a contact area of the gas with respect to the piping 56 at constant or at substantially constant.

Abstract translation: 本发明涉及一种流量传感器52，其使包含在液体81中的气体80在管道56中行进，并且通过检测气体80来测量样品的流速。流量传感器52被配置为 以恒定或基本恒定的方式保持气体相对于管道56的接触面积。

公开(公告)号：US08420014B2

公开(公告)日：2013-04-16

申请号：US11962538

申请日：2007-12-21

Applicant: Igor V. Shvets ,  Cecilia Franken ,  Tomasz P. Zawada

Inventor： Igor V. Shvets ,  Cecilia Franken ,  Tomasz P. Zawada

IPC: G01F1/00

CPC classification number: B01L3/0241 ,  B01L2200/061 ,  B01L2200/0615 ,  B01L2200/143 ,  B01L2200/148 ,  B01L2300/0654 ,  G01F1/7086 ,  G01F13/008 ,  G01F15/075 ,  G01F15/0755 ,  G01N35/1016

Abstract: The present invention is directed to a liquid droplet monitoring and measuring apparatus for use with a liquid dispensing system of the type comprising a nozzle having a liquid dispensing tip and means for delivering the dispensed liquid through the nozzle onto a receiving substrate. Further, the invention provides a method of monitoring and measuring the volume of a liquid droplet as it is being dispensed from a liquid dispensing system comprising a nozzle having a dispensing tip. The main use for the invention is in the fields of drug discovery, genomics, medical diagnostics and other life science-related applications. The invention could also be used in other areas for example in the food industry, cosmetic industry or the chemical industry.

Abstract translation: 本发明涉及一种用于液体分配系统的液滴监测和测量装置，该液体分配系统包括具有液体分配尖端的喷嘴和用于将分配的液体通过喷嘴输送到接收基板上的装置。 此外，本发明提供一种监测和测量液滴在从包括具有分配尖端的喷嘴的液体分配系统中分配的体积的方法。 本发明的主要用途是药物发现，基因组学，医学诊断学和其他生命科学相关应用领域。 本发明也可用于例如食品工业，化妆品工业或化学工业的其他领域。