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107 条记录 (耗时 0.028 秒)

    Treatment Method
    73.
    发明申请
    Treatment Method 审中-公开
    治疗方法

    公开(公告)号：US20080293691A1

    公开(公告)日：2008-11-27

    申请号：US12094672

    申请日：2006-11-29

    申请人： Richard Anthony Brigandi ,  Mark Levick ,  William Henry Miller

    发明人： Richard Anthony Brigandi ,  Mark Levick ,  William Henry Miller

    IPC分类号： A61K31/506 ,  A61P9/00 ,  A61K31/55

    CPC分类号： A61K31/506 ,  A61K31/55 ,  A61K31/7052 ,  A61K39/395 ,  Y02P20/582 ,  A61K2300/00

    摘要： The present invention is directed to methods of treating an ocular neovascular disorder in a mammal by administration of pyrimidine derivatives, benzodiazepinyl derivatives and pharmaceutical compositions containing the same. The invention encompasses methods of treating an ocular neovascular disorder by administration of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, (S)-3-oxo-8-[3-(pyridin-2-ylamino)-1-propyloxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetic acid or salts or solvates thereof. Combination therapies for the treatment of ocular neovascular disorders are also encompassed.

    摘要翻译： 本发明涉及通过施用嘧啶衍生物，苯并二氮杂基衍生物和含有它们的药物组合物来治疗哺乳动物眼部新血管障碍的方法。 本发明包括通过施用5 - [[4 - [（2,3-二甲基-2H-吲唑-6-基）甲基氨基] -2-嘧啶基]氨基] -2-甲基苯磺酰胺处理眼新生血管障碍的方法， S）-3-氧代-8- [3-（吡啶-2-基氨基）-1-丙氧基] -2-（2,2,2-三氟乙基）-2,3,4,5-四氢-1H- - 苯并氮杂-4-乙酸或其盐或溶剂化物。 还包括用于治疗眼新生血管障碍的联合疗法。

    TOY PROJECTILE LAUNCHING DEVICES
    75.
    发明申请
    TOY PROJECTILE LAUNCHING DEVICES 审中-公开
    TOY PROJECTILE启动装置

    公开(公告)号：US20060272627A1

    公开(公告)日：2006-12-07

    申请号：US11421625

    申请日：2006-06-01

    申请人： Ruben Martinez ,  Steed Sun ,  Henry Miller ,  Michael Strauss

    发明人： Ruben Martinez ,  Steed Sun ,  Henry Miller ,  Michael Strauss

    IPC分类号： F41B7/00

    CPC分类号： F41B7/08 ,  A63H17/006

    摘要： Toy projectile launching devices comprising a projectile and a carrying case for housing the projectile in a stowed position. The carrying-case includes a base member, a cover member configured to pivot relative to the base member about an axis of rotation between a range of open positions and a closed position in which the cover member engages the base member, and a launching unit operatively coupled to the base member at an end region generally distal the axis of rotation. The launching unit is configured to engage the projectile, pivotally bias the projectile from the stowed position to a launch position, and launch the projectile.

    摘要翻译： 玩具射弹发射装置包括一个弹丸和一个用于将弹体放置在收起位置的手提箱。 所述手提箱包括基座构件，盖构件，所述盖构件构造成围绕所述打开位置的范围和所述盖构件接合所述基座构件的关闭位置之间的旋转轴线相对于所述基座构件枢转，以及可操作地启动的发射单元 在大致远离旋转轴线的端部区域处联接到基部构件。 发射单元被配置为接合射弹，将射弹从收起位置枢轴偏置到发射位置，并发射抛射体。