公开(公告)号：US5801284A

公开(公告)日：1998-09-01

申请号：US795985

申请日：1997-02-05

Applicant: Franz-Josef Mais ,  Klaus-Christian Paetz ,  Helmut Fiege ,  Heinz Ulrich Blank ,  Dieter Brueck ,  Wolf Mehl

Inventor： Franz-Josef Mais ,  Klaus-Christian Paetz ,  Helmut Fiege ,  Heinz Ulrich Blank ,  Dieter Brueck ,  Wolf Mehl

IPC: C07D231/38 ,  B01J25/02 ,  C07B43/04 ,  C07B61/00 ,  C07C209/36 ,  C07C231/12 ,  C07C233/80 ,  C07C233/81 ,  C07D231/40 ,  C07D231/52

CPC classification number: C07C209/365 ,  C07D231/52

Abstract: Process for preparing haloaromatic amines by catalytic hydrogenation of the corresponding halonitroaromatic compounds, characterized in that iron-containing Raney nickel is used as catalyst, where the haloaromatic amines prepared can be used for the synthesis of photographic couplers which are useful in photographic emulsions or elements.

Abstract translation: 通过相应的卤代硝基芳族化合物的催化氢化制备卤代芳族胺的方法，其特征在于使用含铁阮内镍作为催化剂，其中所制备的卤代芳族胺可用于合成可用于感光乳剂或元素的照相成色剂。

公开(公告)号：US5801276A

公开(公告)日：1998-09-01

申请号：US910442

申请日：1997-08-05

Applicant: Karl-Heinz Neumann ,  Winfried Joentgen ,  Dieter Heitkamp ,  Helmut Fiege

Inventor： Karl-Heinz Neumann ,  Winfried Joentgen ,  Dieter Heitkamp ,  Helmut Fiege

IPC: C07C51/285 ,  C07C59/01 ,  C07C51/235

CPC classification number: C07C51/285

Abstract: Hydroxypivalic acid can be prepared by oxidation of hydroxypivalaldehyde with hydrogen peroxide by metering the hydrogen peroxide, as the oxidizing agent, into an aqueous hydroxypivalaldehyde reservoir in the temperature range from 60.degree. to 80.degree. C. such that a hydrogen peroxide concentration of 4% by weight, based on the total weight of the reaction mixture, is not exceeded, and ending the addition of hydrogen peroxide as soon as the concentration of hydroxypivalaldehyde in the reaction mixture falls below 1% by weight.

Abstract translation: 羟基新戊酸可以通过用过氧化氢氧化羟基新戊醛来制备，通过将过氧化氢作为氧化剂计量到在60℃至80℃的温度范围内的羟基新戊醛水溶液储存器中，使得过氧化氢浓度为4％ 不超过反应混合物的总重量，并且一旦反应混合物中羟基新戊醛的浓度降至低于1重量％，则结束加入过氧化氢。

公开(公告)号：US5780638A

公开(公告)日：1998-07-14

申请号：US762625

申请日：1996-12-09

Applicant: Helmut Kraus ,  Helmut Fiege

Inventor： Helmut Kraus ,  Helmut Fiege

IPC: C07D277/24

CPC classification number: C07D277/24

Abstract: 5-Hydroxymethylthiazole is prepared in an improved manner by reducing 5-formylthiazole using a borane compound. Particularly advantageous in this case is the use of 5-formylthiazole which has been obtained by reaction of a 2-halomalonaldehyde compound with thioformamide in the presence of less than 5% by weight of water (based on the reaction mixture).

Abstract translation: 使用硼烷化合物还原5-甲酰基噻唑，以改进的方式制备5-羟基甲基噻唑。 在这种情况下特别有利的是使用5-甲酰基噻唑，其通过2-卤代甲醛化合物与硫代甲酰胺在小于5重量％的水（基于反应混合物）的存在下反应获得。

公开(公告)号：US5670694A

公开(公告)日：1997-09-23

申请号：US610772

申请日：1996-03-04

Applicant: Ferdinand Hagedorn ,  Helmut Fiege ,  Reinhard Lantzsch

Inventor： Ferdinand Hagedorn ,  Helmut Fiege ,  Reinhard Lantzsch

IPC: B01J27/198 ,  C07B61/00 ,  C07C253/28 ,  C07C253/34 ,  C07C255/50 ,  C07C253/24

CPC classification number: C07C253/28

Abstract: A mixture of 2,4-dichloro-5-fluorotoluene and 2,6-dichloro-3-fluorotoluene which cannot be separated in an economically efficient manner and can be reacted individually to give the corresponding benzonitriles is subjected according to the invention to ammoxidation in the form of this mixture and then separated at the stage of the benzonitriles by methods known to the person skilled in the art.

Abstract translation: 不能以经济有效的方式分离并且可以单独反应得到相应的苯腈的2,4-二氯-5-氟甲苯和2,6-二氯-3-氟甲苯的混合物根据本发明进行氨氧化 该混合物的形式，然后通过本领域技术人员已知的方法在苯甲腈的阶段分离。

公开(公告)号：US5585521A

公开(公告)日：1996-12-17

申请号：US532909

申请日：1995-09-22

Applicant: Wolfram Eichinger ,  Helmut Fiege

Inventor： Wolfram Eichinger ,  Helmut Fiege

IPC: C07C241/02 ,  C07C243/14 ,  C07C243/16 ,  C07C243/18

CPC classification number: C07C241/02

Abstract: Alkylhydrazine salts are prepared on an industrial scale and with good results by reacting together hydrazine, an alkene and a strong protonic acid in the presence of water, hydrazine and the protonic acid being introduced, the alkene being added, the liquid and gaseous phases present in the reaction vessel being intensively mixed together at 75.degree. to 150.degree. C., then the reaction mixture being cooled to temperatures below 60.degree. C., the precipitated alkylhydrazine salt being separated off, hydrazine and strong protonic acid being again added to the mother liquor, then alkene being added again and the next reaction cycle being thus carried out.

Abstract translation: 在工业规模上制备烷基肼盐，并且在水，肼和引入的质子酸，加入的烯烃，存在的液体和气相中，肼，烯烃和强质子酸之间使肼， 将反应容器在75〜150℃剧烈混合，然后将反应混合物冷却至低于60℃的温度，分离出沉淀的烷基肼盐，再将肼和强质子酸加入到母液中 然后再次加入烯烃，从而进行下一个反应循环。

公开(公告)号：US5574188A

公开(公告)日：1996-11-12

申请号：US549241

申请日：1995-10-27

Applicant: Horst Behre ,  Helmut Fiege ,  Heinz-Ulrich Blank ,  Uwe Heinz ,  Wolfgang Eymann

Inventor： Horst Behre ,  Helmut Fiege ,  Heinz-Ulrich Blank ,  Uwe Heinz ,  Wolfgang Eymann

IPC: C07C201/08 ,  B01J23/44 ,  C07B61/00 ,  C07C205/12 ,  C07C205/37 ,  C07C213/02 ,  C07C215/80 ,  C07C213/00

CPC classification number: C07C201/08 ,  C07C201/12 ,  C07C213/02

Abstract: 4,6-diaminoresorcinol can be prepared in a plurality of steps in such a way thata) 1,3-dichlorobenzene is nitrated with a mixed acid of HNO.sub.3, H.sub.2 SO.sub.4 and SO.sub.3 at 0 to 40.degree. C. in anhydrous H.sub.2 SO.sub.4,b) the resulting 1,3-dichloro-4,6/2,4-dinitrobenzene isomeric mixture is first reacted with benzyl alcohol in the presence of a strong base at -15.degree. C. to +15.degree. C. and then at 20.degree. to 40.degree. C. to give the dibenzyloxy compound andc) the 1,3-dibenzyloxy-4,6-dinitrobenzene isomer arising in pure form in b) is converted to the 4,6-diaminoresorcinol by catalytic hydrogenation.

Abstract translation: 可以以多个步骤制备4,6-二氨基间苯二酚，使得a）在无水H 2 SO 4中在0至40℃下用HNO 3，H 2 SO 4和SO 3的混合酸硝化1,3-二氯苯，b） 所得的1,3-二氯-4,6 / 2,4-二硝基苯异构体混合物首先在强碱存在下在-15℃至+ 15℃下与苄醇反应，然后在20℃至 40℃，得到二苄氧基化合物，和c）在b）中以纯形式产生的1,3-二苄氧基-4,6-二硝基苯异构体通过催化氢化转化为4,6-二氨基间苯二酚。

公开(公告)号：US5475163A

公开(公告)日：1995-12-12

申请号：US369560

申请日：1995-01-06

Applicant: Karl H. Neumann ,  Wolfram Kissener ,  Helmut Fiege

Inventor： Karl H. Neumann ,  Wolfram Kissener ,  Helmut Fiege

IPC: C07C201/08 ,  C07C205/12 ,  C07C205/06

CPC classification number: C07C201/08

Abstract: 2,3-dichloro-nitrobenzene can be prepared by nitration of 1,2-dichlorobenzene using an anhydrous mixture of phosphoric acid, sulphuric acid and nitric acid. The conditions according to the invention displace the ratio of 2,3,-dichloro-nitrobenzene and 3,4-dichloro-nitrobenzene in favor of the 2,3-isomer.

Abstract translation: 可以使用磷酸，硫酸和硝酸的无水混合物硝化1,2-二氯苯来制备2,3-二氯 - 硝基苯。 根据本发明的条件取代2,3-二氯硝基苯和3,4-二氯硝基苯的比例，有利于2,3-异构体。

公开(公告)号：US5463068A

公开(公告)日：1995-10-31

申请号：US255024

申请日：1994-06-07

Applicant: Ferdinand Hagedorn ,  Helmut Fiege ,  Hans-Joachim Traenckner

Inventor： Ferdinand Hagedorn ,  Helmut Fiege ,  Hans-Joachim Traenckner

IPC: B01J23/75 ,  B01J23/755 ,  C07B61/00 ,  C07D235/06 ,  C07D277/62 ,  C07D277/72 ,  C07D277/82 ,  C07D235/04

CPC classification number: C07D235/06 ,  C07B61/00 ,  C07D277/62

Abstract: Organic compounds of reduced sulphur content and sulphur-free organic compounds can be prepared from organic mercapto and/or disulphide compounds in a particularly advantageous manner by hydrogenolytic elimination of hydrogen sulphide if the elimination of hydrogen sulphide is carried out in the presence of an organic solvent by means of an aqueous, non-oxidizing, strong acid and elemental iron, aluminium and/or zinc in the presence of catalytic amounts of nickel and/or cobalt.

Abstract translation: 减少硫含量的有机化合物和无硫有机化合物可以通过有机巯基和/或二硫化物化合物以特别有利的方式通过硫化氢的氢解消除来制备，如果在有机溶剂存在下进行硫化氢的消除 在催化量的镍和/或钴存在下，通过水性，非氧化性强酸和元素铁，铝和/或锌。

公开(公告)号：US5382686A

公开(公告)日：1995-01-17

申请号：US70482

申请日：1993-06-02

Applicant: Ferdinand Hagedorn ,  Helmut Fiege

Inventor： Ferdinand Hagedorn ,  Helmut Fiege

IPC: C07B61/00 ,  C07C67/00 ,  C07C201/00 ,  C07C201/12 ,  C07C205/38 ,  C07C213/00 ,  C07C217/90 ,  C07C253/00 ,  C07C255/50 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C315/04 ,  C07C317/22 ,  C07C319/14 ,  C07C323/09 ,  C07C323/18 ,  C07C323/20 ,  C07C323/37 ,  C07C323/62 ,  C07C323/65 ,  C07C211/45

CPC classification number: C07C201/12 ,  C07C213/06 ,  C07C253/30 ,  C07C319/14 ,  C07C319/20

Abstract: Nitrodiphenyl(thio) ethers in which the nitro group is in the ortho- or para-position with respect to the ether oxygen or ether sulphur can be prepared from halonitrobenzones in which the nitro group is in the ortho- or para-position with respect to the halogen and, alkali metal (thio)phenolates in liquid ammonia, the reaction being carried out under pressure and at a temperature from -30.degree. C. to +140.degree. C. and the ammonia being separated off after the reaction is completed.

Abstract translation: 相对于醚氧或醚硫，硝基位于邻位或对位的硝基二苯基（硫代）醚可由卤代硝基苯酮制备，其中硝基相对于邻位或对位为硝基 在液氨中的卤素和碱金属（硫代）酚盐，反应在压力和-30℃至+ 140℃的温度下进行，反应完成后分离出氨。

公开(公告)号：US5130493A

公开(公告)日：1992-07-14

申请号：US681244

申请日：1991-04-05

Applicant: Albert Schnatterer ,  Helmut Fiege ,  Karl-Heinz Neumann

Inventor： Albert Schnatterer ,  Helmut Fiege ,  Karl-Heinz Neumann

IPC: B01J31/22 ,  B01J31/12 ,  B01J31/18 ,  C07B61/00 ,  C07C45/36 ,  C07C47/565 ,  C07C47/575

CPC classification number: C07C45/36 ,  B01J31/183 ,  B01J2531/0241 ,  B01J2531/72 ,  B01J2531/842

Abstract: o-Hydroxy-benzaldehydes can be obtained by oxidation of the o-cresols, on which they are based, with oxygen in the presence of substances having a base reaction in a solvent if chelate complexes of iron, manganese or a mixuture of both with polyaza-macrocycles as chelating agents are employed as catalysts. Copper or a copper compound is advantageously added as a co-catalyst.

Abstract translation: 邻羟基苯甲醛可以通过在它们所基于的邻甲酚的氧化作用下，在溶剂中具有碱反应的物质存在下，如果铁，锰的螯合络合物或两者的混合物 作为螯合剂的大环化合物被用作催化剂。 铜或铜化合物有利地作为助催化剂加入。