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公开(公告)号：US11891668B2
公开(公告)日：2024-02-06
申请号：US17514724
申请日：2021-10-29
Inventor： Mei He
IPC: A61K47/00 , C12Q1/6886 , A61K47/69 , G01N33/574 , G01N33/543 , B03C1/015 , B03C1/30 , B01L3/00 , A61K49/00
CPC classification number: C12Q1/6886 , A61K47/6901 , A61K49/0097 , B01L3/502715 , B01L3/502761 , B03C1/015 , B03C1/30 , G01N33/5434 , G01N33/54333 , G01N33/574 , C12Q2600/156 , C12Q2600/158 , C12Q2600/178 , G01N2446/80
Abstract: Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments.
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公开(公告)号：US20230189786A1
公开(公告)日：2023-06-22
申请号：US17559397
申请日：2021-12-22
Inventor： Andrew W. Harmon , Ajay Sharda
CPC classification number: A01M7/0089 , B05B1/20 , B05B12/084 , B05B12/085 , G05B15/02
Abstract: An agricultural system can include a product application system including one or more nozzle assemblies. A sensing system can include at least one flow sensor operably coupled with the product application system and configured to capture data indicative of a flow condition within the product application system. A computing system is communicatively coupled to the product application system and the sensing system. The computing system can be configured to calculate a spray quality index based on data from the sensing system, detect a pressure drop within the product application system based on the data indicative of a flow condition within the product application system, and generate an output based on the spray quality index and/or the detection of one or more pressure drops in the product application system.
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公开(公告)号：US20230128983A1
公开(公告)日：2023-04-27
申请号：US18045280
申请日：2022-10-10
Inventor： James Scott DROUILLARD , Celine Caroline Aperce , Gina Rae Herren , Tara Jo Ellerman , Ciana Marie Scaletti , Katherine Van Jordan , James Morris Lattimer , Scott Beyer , Solange Uwituze , Teresa Lea Douthit , Christina Denise Gunkel
Abstract: The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals.
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公开(公告)号：US20230103224A1
公开(公告)日：2023-03-30
申请号：US17911221
申请日：2021-03-11
Applicant: Kansas State University Research Foundation
Inventor： George T. Amariucai , Pascal Hitzler , Abhishek Jana , Monireh Ebrahimi , Md Kamruzzaman Sarker
IPC: H04L9/32
Abstract: Computer-implemented methods, systems and computer-readable media for building and using an artificial intelligence model for secure biometric authentication. Utilizing difference vectors, the model securely relates output vectors generated from noisy biometric data of a plurality of enrolled users to pre-defined fixed points in a vector space.
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公开(公告)号：US11612623B2
公开(公告)日：2023-03-28
申请号：US16692411
申请日：2019-11-22
Applicant: Kansas State University Research Foundation
Inventor： Megan C. Niederwerder
IPC: A61K35/745 , A23K50/30 , A23K10/18 , A61K9/00 , A61K35/00
Abstract: The present disclosure provides compositions and methods for improving disease resistance, increasing weight gain, and reducing the incidence and/or severity of clinical signs of infection. The composition generally comprises one or more microorganisms that is administered to an animal in need thereof. Preferred infections that can be combated with the compositions and methods of this disclosure are respiratory infections including PRRSV and PCV2.
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Patent Agency Ranking
公开(公告)号：US20230029979A1
公开(公告)日：2023-02-02
申请号：US17755359
申请日：2020-10-30
Applicant: Kansas State University Research Foundation
Inventor： Waithaka Mwangi , Huldah Sang
IPC: C12N15/86
Abstract: A vector comprising a BPI3Vc backbone and at least one antigenic insert sequence from a pathogen other than BPI3V is provided. The vector is configured to provide protection against BPI3V as well as against the pathogen from which the insert sequence was obtained.
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77.发明申请公开(公告)号：US20220380731A1
公开(公告)日：2022-12-01
申请号：US17774968
申请日：2020-11-05
Applicant: Kansas State University Research Foundation
Inventor： Mark L. Weiss , Adrienne Wright
IPC: C12N5/0775
Abstract: Methods for improved handling of isolated canine umbilical cord mesenchymal stromal cells (UC-MSCs), including methods for expansion of canine UC-MSCs, cryopreservation and improved post-thaw viability using adherent plates, as well as standardized methods and kits for characterizing isolated canine UC-MSCs in a cell population. Methods for improved detachment or dissociation of adherent cells and new dissociation reagents comprising nattokinase are also disclosed.
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公开(公告)号：US11492629B2
公开(公告)日：2022-11-08
申请号：US16811265
申请日：2020-03-06
Applicant: Kansas State University Research Foundation
Inventor： Mithila Jugulam , Dal-Hoe Koo , Bikram S. Gill , Bernd Friebe
IPC: C12N15/82
Abstract: Methods of modifying plants by amplifying native or introducing extrachromosomal circular plant DNA comprising one or more exogenous or endogenous genes conferring an agronomically useful trait when expressed in a plant, or disrupting the association or tethering of endogenous extrachromosomal circular plant DNA with endogenous chromosomes in a plant to change one or more plant traits.
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公开(公告)号：US11492587B2
公开(公告)日：2022-11-08
申请号：US16481962
申请日：2018-01-31
Inventor： James Scott Drouillard , Celine Caroline Aperce , Gina Rae Herren , Tara Jo Ellerman , Ciana Marie Scaletti , Katherine Van Jordan , James Morris Lattimer , Scott Beyer , Solange Uwituze , Teresa Lea Douthit , Christina Denise Gunkel
Abstract: The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals.
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公开(公告)号：US20220347450A1
公开(公告)日：2022-11-03
申请号：US17862315
申请日：2022-07-11
Inventor： Jungkwun KIM , Keun Ho LEE , Jung Dong KIM , Dohyeon JEONG
Abstract: Lithography fabrication methods for producing polymeric microneedles, microprobes, and other micron-sized structures with sharp tips. The fabrication process utilizes a single-step bottom-up exposure of photosensitive resin through a photomask micro-pattern, with a corresponding change/increase in refractive index of the resin creating a meta-state waveguide within the resin which focuses down additional transmitted energy and forms a converging shape (first harmonic microcone). Energy is diffracted through the tip of the first harmonic microcone as a second harmonic beam to form a second converging shape (second harmonic shape) adjacent the first microcone, followed by additional tertiary harmonic microcones, which can be built upon these structures with application of additional energy.
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