公开(公告)号：US12136197B2

公开(公告)日：2024-11-05

申请号：US17519929

申请日：2021-11-05

Applicant: Massachusetts Institute of Technology

Inventor： Michael Newey ,  Prafull Sharma

IPC: G06T5/70 ,  G01S17/89 ,  G06N3/045 ,  G06N3/088 ,  G06T5/50

Abstract: A neural network is used to remove noise from a data signal. The noise removed by the neural network is compared to simulated noise that represents noise expected to be present in the data signal. The results of the comparison are used to train the neural network and improve its ability to remove noise from the data signal.

公开(公告)号：US12135254B2

公开(公告)日：2024-11-05

申请号：US17665186

申请日：2022-02-04

Applicant: Massachusetts Institute of Technology

Inventor： Edward Adelson ,  Sandra Liu

IPC: G01L1/24 ,  G01L5/00

Abstract: A retrographic sensor includes a flexible transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. The flexible transparent structure may be configured to elastically deform between multiple configurations. At least one light source emits light into the transparent structure. The flexible transparent structure may include one or more markers that are illuminated by the at least one light source. The retrographic sensor may also include a photosensitive detector configured to image the flexible transparent structure and one or more markers. A processor may determine a configuration of the flexible transparent structure based at least in part on an image from the one or more markers.

公开(公告)号：US20240362466A1

公开(公告)日：2024-10-31

申请号：US18308167

申请日：2023-04-27

Applicant: International Business Machines Corporation ,  Massachusetts Institute Of Technology

Inventor： Ramon Fernandez Astudillo ,  Andrew Drozdov ,  Jiawei Zhou ,  Radu Florian ,  Tahira Naseem ,  Yoon Hyung Kim

IPC: G06N3/0475 ,  G06N3/047 ,  G06N5/045

CPC classification number: G06N3/0475 ,  G06N3/047 ,  G06N5/045

Abstract: Systems, computer-implemented methods, and computer program products to facilitate reducing error propagation when combining generative aligners and transition-based aligners are provided. According to an embodiment, a system can comprise a processor that executed components stored in memory. The computer executable components comprise a generative alignment component, an error propagation component, a discriminative parser, and a stochastic oracle policy component. The error propagation component can compute a posterior distribution over one or more hard alignments of parts given a pair of the generative alignment component. The discriminative parser can be trained via the stochastic oracle policy component to reduce error propagation when combining the generative alignment component with the discriminative parser.

公开(公告)号：US20240358502A1

公开(公告)日：2024-10-31

申请号：US18655491

申请日：2024-05-06

Applicant: Children's Medical Center Corporation ,  President and Fellows of Harvard College ,  Massachusetts Institute of Technology

Inventor： Sophie-Charlotte Hofferberth ,  Pedro J. del Nido ,  Elazer R. Edelman ,  Peter E. Hammer ,  Christopher Payne

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2250/0004 ,  A61F2250/0065 ,  A61F2250/0082

Abstract: A replacement heart valve device is disclosed. In some embodiments, the device includes a frame coupled to one or more leaflets that are moveable between open and closed configurations. In some embodiments, the frame comprises at least two frame sections that join at a pair of commissural posts. In some embodiments, the device may be geometrically accommodating to adapt to different vasculature shapes and sizes and/or to be able to change size while implanted within a growing patient.

公开(公告)号：US12131276B2

公开(公告)日：2024-10-29

申请号：US15409653

申请日：2017-01-19

Applicant: Massachusetts Institute of Technology

Inventor： Carlo Filippo Ratti ,  Giovanni Resta ,  Paolo Santi

IPC: G06Q10/00 ,  G06Q10/0631 ,  G06Q50/00 ,  G06Q50/40 ,  G08G1/00

CPC classification number: G06Q10/06313 ,  G06Q10/06315 ,  G06Q50/40 ,  G08G1/202

Abstract: Real-time, point-to-point, on-demand ride dispatching system. The system provides for optimal operation including a fleet dimensioning module for determining an optimal number of vehicles in a fleet needed to serve a collection of trip requests, and a vehicle dispatching module for dispatching the fleet of vehicles to serve a selected number of trip requests. The fleet dimensioning module employs a shareability network to model trip requests that can be served by a same vehicle to find the minimum number of vehicles in the fleet to serve all trip requests in the collection of trip requests.

公开(公告)号：US12130281B2

公开(公告)日：2024-10-29

申请号：US17404286

申请日：2021-08-17

Applicant: Massachusetts Institute of Technology ,  President and Fellows of Harvard College

Inventor： Armon R. Sharei ,  Marc Lajoie ,  Klavs F. Jensen ,  Robert S. Langer

IPC: G01N33/487 ,  C12N15/87 ,  G01N33/50 ,  C12Q1/00

CPC classification number: G01N33/5002 ,  C12N15/87 ,  G01N33/48721 ,  C12Q1/00

Abstract: Gene editing can be performed by introducing gene-editing components into a cell by mechanical cell disruption. Related apparatus, systems, techniques, and articles are also described.

公开(公告)号：US12126324B2

公开(公告)日：2024-10-22

申请号：US18558207

申请日：2022-05-06

Applicant: Massachusetts Institute of Technology

Inventor： David J. Perreault ,  Jessica Boles ,  Jeffrey H. Lang ,  Joseph Bonavia

IPC: H03H9/17

CPC classification number: H03H9/17

Abstract: Described are structures and techniques for providing high-efficiency, high-power-density piezoelectric resonators (PRs) for use in power converters. In some embodiments, a power converter can include a PR for energy transfer, where the PR substantially satisfies geometry conditions disclosed herein for achieving high-efficiency and high-power-density. The geometry conditions can be defined in terms of the converter's specified (e.g., rated) voltage and power level.

公开(公告)号：US20240346352A1

公开(公告)日：2024-10-17

申请号：US18294259

申请日：2022-08-02

Applicant: President and Fellows of Harvard College ,  Massachusetts Institute of Technology

Inventor： Dolev Bluvstein ,  Harry Jay Levne ,  Giulia Semeghini ,  Tout WANG ,  Sepehr Ebadi ,  Alexander Keesling Contreras ,  Mikhail D. Lukin ,  Markus Greiner ,  Vladan Vuletic

IPC: G06N10/40 ,  G06N10/20 ,  G06N10/70

CPC classification number: G06N10/40 ,  G06N10/20 ,  G06N10/70

Abstract: Dynamically reconfigurable architectures for quantum information and simulation are provided. A plurality of neutral atoms is provided. Each neutral atom is disposed in a corresponding optical trap. Each of the plurality of neutral atoms is prepared in a mF=0 clock state. A pair of neutral atoms of the plurality of neutral atoms is entangled by directing a laser pulse thereto. The laser pulse is configured to transition the pair of neutral atoms through a Rydberg state. The optical trap corresponding to at least one neutral atom of the pair is adiabatically moved, thereby moving one atom of the pair relative to the other atom of the pair without destroying entanglement of the pair.

公开(公告)号：US20240344991A1

公开(公告)日：2024-10-17

申请号：US18685153

申请日：2022-08-19

Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Inventor： Pil Joong CHUNG ,  Sayuj KOYYAPPURATH ,  Nam-Hai CHUA ,  Rajani SAROJAM ,  Gajendra Pratap SINGH ,  Rajeev J. RAM

IPC: G01N21/65 ,  G01N33/00

CPC classification number: G01N21/65 ,  G01N33/0098

Abstract: The present invention relates to the use of Raman spectroscopy for the real time detection and quantitation of innate immunity response in plants. More specifically, the present invention provides Raman spectroscopy as a tool for rapid, non-invasive, and early detection and quantitation of plant innate immune response.

公开(公告)号：US20240338583A1

公开(公告)日：2024-10-10

申请号：US17357270

申请日：2021-06-24

Applicant: Massachusetts Institute of Technology

Inventor： Martin Zwierlein ,  Thomas Richard Hartke ,  Ningyuan Jia ,  Botond Oreg

IPC: G06N10/40 ,  G01N21/64 ,  G06N10/20 ,  G21K1/00

CPC classification number: G06N10/40 ,  G01N21/6458 ,  G06N10/20 ,  G21K1/003 ,  G21K1/006

Abstract: Fermions are the building blocks of matter. Here, we disclose a robust quantum register composed of hundreds of fermionic atom pairs trapped in an optical lattice. With each fermion pair forming a spin-singlet, the qubit is realized as a set of near-degenerate, symmetry-protected two-particle wavefunctions describing common and relative motion. Degeneracy is lifted by the atomic recoil energy, which depends on mass and lattice wavelength, thereby rendering two-fermion motional qubits insensitive to noise of the confining potential. The quantum coherence can last longer than ten seconds. Universal control is provided by modulating interactions between the atoms. Via state-dependent, coherent conversion of free atom pairs into tightly bound molecules, we tune the speed of motional entanglement over three orders of magnitude, yielding 104 Ramsey oscillations within the coherence time. For site-resolved motional state readout, pairs are coherently split into their constituent fermions via a double-well, creating entangled Bell pairs.