公开(公告)号：US20050207901A1

公开(公告)日：2005-09-22

申请号：US10805835

申请日：2004-03-22

申请人： Joseph Klobucar ,  James Pakkala ,  Mazen Haddad ,  David Cole

发明人： Joseph Klobucar ,  James Pakkala ,  Mazen Haddad ,  David Cole

IPC分类号： B05B7/14 ,  F04B49/00 ,  F04F1/02 ,  F04F1/18 ,  F04F5/48 ,  F04F5/54

CPC分类号： B05B7/1459 ,  F04F1/02 ,  F04F1/18 ,  F04F5/54

摘要： A pump for transferring particulate material from a source to a remote location, including a particulate chamber having open ends, check valves at the open ends, a vacuum source connected to the chamber adjacent one end, a gas source at the opposed end of the chamber and a control which alternatively connects the vacuum to the chamber to draw particulate material from the source to the chamber and connecting the gas under pressure to drive the particulate material to the remote location. In a preferred embodiment, the chamber has a cylindrical inner diameter and the source of vacuum is a venturi pump connected to a pinch valve permitting overflow of particulate material through the pinch valve and venturi pump, which is returned to the source. In one embodiment, the pinch valve surrounds an open end of the chamber permitting overflow while avoiding agglomeration of the particulate material.

摘要翻译： 一种用于将颗粒材料从源传输到远程位置的泵，包括具有开口端的微粒室，在开口端的止回阀，邻近一端连接到腔室的真空源，在腔室的相对端处的气体源 以及将真空交替地连接到室以将颗粒材料从源抽吸到室并且在压力下连接气体以将颗粒材料驱动到远程位置的控制器。 在优选实施例中，腔室具有圆柱形内径，真空源是连接到夹管阀的文丘里泵，允许颗粒材料通过夹送阀和文丘里泵溢出，该泵返回到源头。 在一个实施例中，夹管阀围绕室的开口端，允许溢流，同时避免颗粒材料的团聚。

公开(公告)号：US20050203618A1

公开(公告)日：2005-09-15

申请号：US11003693

申请日：2004-12-03

申请人： Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

发明人： Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/2418 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2220/0066 ,  A61F2230/0054 ,  A61F2250/006

摘要： Implantable prosthetic valve systems and methods for implanting them are provided. Magnets are employed within one or more components of the valve systems to facilitate anchoring of the prosthetic valve at a target implant site, delivery of the prosthetic valve to the target implant site or both.

摘要翻译： 提供了植入式假体瓣膜系统及其植入方法。 磁体被用在阀系统的一个或多个部件内，以便于在目标植入部位处将人工瓣膜锚固，将人造瓣膜递送到目标植入部位或两者。

公开(公告)号：US20050192954A1

公开(公告)日：2005-09-01

申请号：US11119917

申请日：2005-05-03

申请人： Sunil Gupta ,  Kevin Hrim ,  David Cole

发明人： Sunil Gupta ,  Kevin Hrim ,  David Cole

IPC分类号： G06F17/30 ,  G09B7/02

CPC分类号： G09B7/02 ,  G06F16/9535 ,  Y10S707/99933 ,  Y10S707/99944 ,  Y10S707/99945

摘要： The present invention relates to delivering adaptive content to a user via a user output device, typically a computer. In general, user information associated with a particular user is retrieved and activity selection and topic selection information are received. A set of one or more questions is retrieved based upon the selected topic and the user information. The retrieved question set is presented to the user in the context of interacting with the selected activity. Progression through the selected activity results from successfully answering the questions. In some instances, questions may be evaluated for bias with respect to particular user group(s). Further, certain embodiments may support assignment of particular topics, questions and/or activities to particular users or user groups. Facilities may also be supported for aiding users in developing and/or expanding the available questions, topics and/or activities.

摘要翻译： 本发明涉及通过用户输出设备（通常为计算机）向用户传送自适应内容。 通常，检索与特定用户相关联的用户信息，并且接收活动选择和主题选择信息。 基于所选择的主题和用户信息来检索一组一个或多个问题。 所检索的问题集在与所选择的活动交互的上下文中呈现给用户。 通过选择的活动进行成功回答问题。 在某些情况下，可以针对特定用户组评估问题的偏差。 此外，某些实施例可以支持将特定主题，问题和/或活动分配给特定用户或用户组。 还可以支持设施帮助用户开发和/或扩展可用的问题，主题和/或活动。

公开(公告)号：US20050123976A1

公开(公告)日：2005-06-09

申请号：US11003223

申请日：2004-12-02

申请人： Michael Mitas ,  David Cole ,  William Gillanders ,  Michael Wallace

发明人： Michael Mitas ,  David Cole ,  William Gillanders ,  Michael Wallace

IPC分类号： A61B20060101 ,  C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118

摘要： Provided is a method for detecting metastases of epithelial cancers, comprising detecting in non-primary tissue overexpression of a nucleic acid of KS1/4, or detecting in non-primary tissue overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx, the overexpression of a nucleic acid of KS1/4, or the overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx in non-primary tissue being correlated with metastases of epithelial cancers.

摘要翻译： 提供了一种用于检测上皮癌转移的方法，包括在非原代组织中检测KS1 / 4核酸的过表达，或检测非小细胞组织过表达KS1 / 4和PIP核酸的组合， KS1 / 4，PIP和mam核酸或KS1 / 4和lunx核酸的PIP和mam的核酸的KS1 / 4和mam的核酸，KS1 / 4的核酸的过表达 或KS1 / 4，PIP和mam核酸或核酸的核酸的PIP和mam的核酸的KS1 / 4和mam的核酸的KS1 / 4和PIP的核酸的组合的过表达或核酸 KS1 / 4的酸和非原发性组织中的lunx与上皮癌的转移相关。

公开(公告)号：US20050021059A1

公开(公告)日：2005-01-27

申请号：US10774345

申请日：2004-02-06

申请人： David Cole ,  Samuel Crews ,  Michael Reo ,  Dean Carson ,  Keke Lepulu ,  Darin Gittings

发明人： David Cole ,  Samuel Crews ,  Michael Reo ,  Dean Carson ,  Keke Lepulu ,  Darin Gittings

IPC分类号： A61B17/00 ,  A61B17/04 ,  A61B17/064 ,  A61B17/11 ,  A61F2/00 ,  A61F2/02 ,  A61F2/06 ,  A61F2/24 ,  A61F2/94 ,  H01F7/02 ,  H01F41/02 ,  A61B17/08

CPC分类号： A61F2/2493 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00876 ,  A61B2017/1107 ,  A61B2017/1132 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61B2018/00392 ,  A61F2/064 ,  A61F2/07 ,  A61F2/94 ,  A61F2002/30079 ,  A61F2210/0076 ,  A61F2210/009 ,  H01F7/0263 ,  H01F41/026

摘要： Methods and devices for forming an anastomosis between hollow bodies utilize magnetic force to couple anastomotic securing components and connect the lumens of the hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created without using suture or any other type of mechanical fasteners, although such attachment means may be used in practicing some aspects of the invention. The securing components have the ability to produce a magnetic field and may include materials or assemblies. A component may also be used to form a port into the lumen of a vessel, the component being attached to the vessel by mechanical and/or magnetic means. Magnetic components may include means for concentrating the magnetic flux between respective components to increase the attraction force, thereby enhancing the security of the anastomosis. Also, rather than form a port communicating with a lumen of a vessel or other cavity, the components may have an occlusion surface and be used to close an opening in tissue, e.g., an atrial septal defect.

摘要翻译： 用于形成中空体之间的吻合的方法和装置利用磁力来联接吻合的固定部件并连接中空体的内腔。 可以在不使用缝合线或任何其它类型的机械紧固件的情况下创建端对侧，侧向对侧和端对端吻合，尽管这些附接手段可用于实践本发明的某些方面。 固定部件具有产生磁场的能力并且可以包括材料或组件。 组件也可用于在容器的内腔中形成端口，该部件通过机械和/或磁性方式附接到容器。 磁性部件可以包括用于将磁通集中在各个部件之间以增加吸引力的装置，从而增强吻合的安全性。 而且，组件可以具有闭塞表面，并且用于封闭组织中的开口，例如房间隔缺损，而不是形成与容器或其它空腔的内腔连通的端口。

公开(公告)号：US06409086B1

公开(公告)日：2002-06-25

申请号：US09190485

申请日：1998-11-12

申请人： John Pellaumail ,  Thomas Roslak ,  David Cole ,  Jerome Swartz ,  Robert Beach

发明人： John Pellaumail ,  Thomas Roslak ,  David Cole ,  Jerome Swartz ,  Robert Beach

IPC分类号： G06K710

CPC分类号： G07G1/0018 ,  G06Q20/343 ,  G07F7/02 ,  G07G1/0081

摘要： A wireless system for self-service shopping is described that includes a customer identification device with an optically readable code, a portable terminal that includes an optical code reader, a local area radio, a terminal controller, and a locking mechanism, a master station, consisting of a master controller and a master radio, and a receiving rack for the portable terminals to which the scanners may be locked using the locking mechanism. A customer presents his or her identification device to a terminal which reads the code, the code is transferred by radio to the master controller which checks the identification and, if valid, sends an authorized signal by radio to the terminal to unlock the scanner. In addition, several locking mechanisms are described that are controlled by the terminal controller. An additional feature provides a shopping cart with a receiving cradle for a portable terminal that allows the customer to lock the scanner onto the cart for hands-free shopping.

摘要翻译： 描述了一种用于自助购物的无线系统，其包括具有光学可读代码的客户识别装置，包括光学代码读取器，局域无线电，终端控制器和锁定机构的便携式终端，主站， 包括主控制器和主无线电装置，以及用于使用锁定机构锁定扫描仪的便携式终端的接收架。 客户将其识别装置呈现给读取代码的终端，代码通过无线电传送到主控制器，主控制器检查该标识，并且如果有效，则通过无线电向终端发送授权信号以解锁扫描仪。 此外，描述了由终端控制器控制的几个锁定机构。 附加功能为购物车提供便携式终端的接收支架，允许客户将扫描仪锁定在购物车上以进行免提购物。

公开(公告)号：US5104668A

公开(公告)日：1992-04-14

申请号：US645543

申请日：1991-01-24

申请人： David Cole ,  Andreas Schmidt

发明人： David Cole ,  Andreas Schmidt

IPC分类号： A23L17/30 ,  A23L17/40

CPC分类号： A23L17/40 ,  A23L17/30 ,  Y10S426/805

摘要： A process for treating Artemia brine shrimp cysts, which are deemed unhatchable, by the following steps: rehydrating the cysts in clear water until they are approximately double their weight; mechanically rupturing the rehydrated cysts without destroying the internal embryo content of the cysts; centrifuging the resulting slurry to extract the content of the cysts from fragmented casings; and processing the slurry to stabilize the contained nutritional values thereof.

摘要翻译： 通过以下步骤处理被认为是不可孵出的卤虫盐虾虾囊肿的方法：将清水中的囊肿再水合至其重量的大约两倍; 机械地破坏再水合的囊肿，而不破坏囊肿的内胚胎含量; 将得到的浆液离心以从碎片壳中提取囊肿的含量; 并处理浆料以稳定其含有的营养价值。