公开(公告)号：US09386944B2

公开(公告)日：2016-07-12

申请号：US12421776

申请日：2009-04-10

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/15 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/157 ,  A61B5/151

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150259 ,  A61B5/150419 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150702 ,  A61B5/150946 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15176 ,  A61B5/15182 ,  A61B5/157 ,  A61B2562/0295

摘要： An integrated analyte measurement system includes a housing and a disposable configured to be positioned in the housing. A plurality of penetrating members are positioned in the disposable. A penetrating member driver is configured to be coupled to each of a penetrating member. A plurality of analyte sensors are positioned in the disposable. The disposable houses both used and unused penetrating members and analyte sensors.

公开(公告)号：US09314194B2

公开(公告)日：2016-04-19

申请号：US11622389

申请日：2007-01-11

申请人： Ajay Deshmukh ,  Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Ajay Deshmukh ,  Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00 ,  B65D81/00 ,  A61B17/32 ,  A61B5/15 ,  A61B5/155 ,  A61B5/151 ,  A61M5/00

CPC分类号： A61B5/1411 ,  A61B5/1427 ,  A61B5/150022 ,  A61B5/150061 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15174 ,  A61B5/15176 ,  A61B5/15178 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/157 ,  A61M2005/005

摘要： A body fluid sampling system is provided for use on a tissue site. A drive force generator is coupled to penetrating members. The penetrating members are at least partially housed in a penetrating member housing. The penetrating member housing has openings for the penetrating members. The penetrating members are launched along a launch path by the drive force generator through an opening in the penetrating member housing. Analyte sensors are housed in a analyte sensor housing. Each analyte sensor is associated with a penetrating member. The analyte sensor housing and the penetrating member housing are coupled to provide that each analyte sensor is positioned out of a launch path of a penetrating member. The analyte sensor housing includes desiccant pockets for receiving desiccant plugs.

摘要翻译： 提供体液采样系统用于组织部位。 驱动力发生器联接到穿透构件。 穿透构件至少部分地容纳在穿透构件壳体中。 穿透构件壳体具有用于穿透构件的开口。 穿透构件通过驱动力发生器沿着发射路径通过穿透构件壳体中的开口而发射。 分析物传感器容纳在分析物传感器外壳中。 每个分析物传感器与穿透构件相关联。 分析物传感器壳体和穿透构件壳体被联接以提供每个分析物传感器位于穿透构件的发射路径之外。 分析物传感器外壳包括用于接收干燥剂塞的干燥剂袋。

公开(公告)号：US08496601B2

公开(公告)日：2013-07-30

申请号：US11735817

申请日：2007-04-16

申请人： Barry Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

发明人： Barry Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150832 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/150954 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15174 ,  A61B5/15176 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/1519 ,  A61B5/15194 ,  A61B17/32093 ,  B01L3/5027 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet and a processor coupled to the drive force generator capable of changing the direction and magnitude of force exerted on the lancet during the lancing cycle. The driver further includes a human interface on the housing providing at least one output for communicating with the patient.

摘要翻译： 提供了一种刺血针驱动器，其中驾驶员在穿刺周期期间在柳叶刀上施加驱动力并且在组织部位上使用。 驱动器包括用于使柳叶刀前进的驱动力发生器和与驱动力发生器耦合的处理器，其能够改变在穿刺周期期间施加在刺血针上的力的方向和大小。 驱动器还包括在壳体上的人机接口，提供至少一个用于与患者通信的输出。

公开(公告)号：US08262614B2

公开(公告)日：2012-09-11

申请号：US10558865

申请日：2004-06-01

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61M31/00 ,  A61M37/00 ,  A61B5/00

CPC分类号： A61B5/157 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150183 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150824 ,  A61B5/150954 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15176 ,  A61B5/15182 ,  A61B5/7445 ,  A61M5/20 ,  A61M5/282 ,  A61M5/3291 ,  A61M2005/004 ,  A61M2005/005 ,  A61M2005/206 ,  A61N2/002

摘要： A device is provided for fluid delivery. The device comprises a cartridge having a plurality of cavities and a plurality of penetrating members. The plurality of penetrating members are each at least partially contained in cavities of the cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue. Each of the penetrating members comprises a needle with a lumen coupled to a canister containing a material to be injected.

摘要翻译： 提供了用于流体输送的装置。 该装置包括具有多个空腔和多个穿透构件的盒。 多个穿透构件各自至少部分地容纳在盒的空腔中，其中穿透构件可滑动地移动以从所述盒上的开口向外延伸以穿透组织。 每个穿透构件包括具有与容纳待注射材料的罐连接的腔的针。

公开(公告)号：US08197423B2

公开(公告)日：2012-06-12

申请号：US12967139

申请日：2010-12-14

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150519 ,  A61B5/150572 ,  A61B5/150664 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/151 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/15182 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/157 ,  A61M37/0015

摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 墨盒容纳穿透构件。 筒具有联接到穿透构件的第一和第二密封件，以在穿透构件致动之前保持穿透构件的一部分周围的无菌环境。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。

公开(公告)号：US20120130343A1

公开(公告)日：2012-05-24

申请号：US13184644

申请日：2011-07-18

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden ,  Barry Dean Briggs ,  Jon Hewitt Leonard ,  Ray Freeman ,  George Gogue

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden ,  Barry Dean Briggs ,  Jon Hewitt Leonard ,  Ray Freeman ,  George Gogue

IPC分类号： A61M5/31

CPC分类号： A61M5/46 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150061 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15176 ,  A61B5/15178 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/157 ,  A61B17/32093 ,  A61M5/158 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502746 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905 ,  G01N33/557 ,  G06F19/00

摘要： An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft.

摘要翻译： 提供了能够将药剂注射到已知的预定组织深度的药剂注射装置。 注射构件具有细长注射轴，其具有配置成在可控制时间分配药剂的出口端口。 可控制的驱动器联接到细长注射轴并被构造成将注射构件驱动到靶组织中。 速度控制系统与可控驱动器连通，并被配置成控制细长注射轴的速度。

公开(公告)号：US07909774B2

公开(公告)日：2011-03-22

申请号：US11674203

申请日：2007-02-13

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/15107 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/157 ,  A61B17/32093 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

公开(公告)号：US07798979B2

公开(公告)日：2010-09-21

申请号：US12102455

申请日：2008-04-14

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  B65D81/00

CPC分类号： A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150519 ,  A61B5/150572 ,  A61B5/150664 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/151 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/15182 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/157 ,  A61M37/0015

摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid.

摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1μL的流体的样品来确定流体中的分析物的浓度。

公开(公告)号：US20070219573A1

公开(公告)日：2007-09-20

申请号：US11737818

申请日：2007-04-20

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B17/34

CPC分类号： A61B5/15178 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/15107 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/157

摘要： A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. A support is provided with a plurality of openings. Each opening receives a penetrating member. Each tip of a penetrating member is uncovered during launch of a penetrating member by the penetrating driver member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

摘要翻译： 组织穿透系统包括各自具有尖端的多个穿透构件。 穿透构件驱动器联接到多个穿透构件。 支撑件设置有多个开口。 每个开口接收穿透构件。 穿透构件的每个尖端在通过穿透驱动构件发射穿透构件时未被覆盖。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。

公开(公告)号：US20070073189A1

公开(公告)日：2007-03-29

申请号：US11536725

申请日：2006-09-29

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15176 ,  A61B5/15178 ,  A61B5/15184 ,  A61B5/157 ,  A61B17/32093 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

摘要翻译： 组织穿透系统具有壳体构件。 多个穿透构件定位在壳体构件中。 组织稳定构件联接到壳体。 穿透构件传感器联接到多个穿透构件。 穿透构件传感器被配置为提供关于穿透构件穿过皮肤表面的穿透深度的信息。