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    Novel indole derivative for alkylating specific base sequence of dna and alkylating agent and drug containing the derivative
    71.
    发明申请
    Novel indole derivative for alkylating specific base sequence of dna and alkylating agent and drug containing the derivative 失效
    用于烷基化dna和烷化剂的特异性碱基序列的新型吲哚衍生物和含有衍生物的药物

    公开(公告)号：US20070191260A1

    公开(公告)日：2007-08-16

    申请号：US10598789

    申请日：2005-03-10

    申请人： Hiroshi Sugiyama ,  Toshikazu Bando

    发明人： Hiroshi Sugiyama ,  Toshikazu Bando

    IPC分类号： A61K38/04 ,  A61K31/7052 ,  A61K31/407 ,  A61K31/4178 ,  A61K31/405 ,  C07D403/14

    CPC分类号： C07D403/14 ,  C07D487/04

    摘要： There is provided a novel pyrrole-imidazole polyamide compound for alkylating the specific base sequence of DNA, the polyamide compound being capable of being synthesized through fewer reaction steps than known hybrid molecules and having a combination of a high reactivity in DNA alkylation and the ability to recognize a sequence. Furthermore, there is provided an alkylating agent and a molecule serving as a drug, the alkylating agent and the molecule containing the polyamide compound. An indole derivative is represented by general formula (1): wherein R1 represents a functional group for alkylating DNA; R2 represents a hydrogen atom, an alkyl group, or an acyl group; and X represents a divalent group having one constitutional unit or having two or more constitutional units which may be the same or different, the constitutional unit being represented by the following formula: (wherein m is an integer of 0 to 10), wherein among the constitutional units, a terminal constitutional unit adjacent to R2 may be a constitutional unit represented by the following formula: (wherein k is an integer of 0 to 10).

    摘要翻译： 提供了一种用于烷基化DNA特异性碱基序列的新型吡咯 - 咪唑聚酰胺化合物，该聚酰胺化合物能够通过比已知杂化分子更少的反应步骤合成，并且具有DNA烷基化反应性高的能力和 识别序列。 此外，提供烷基化剂和作为药物的分子，烷基化剂和含有聚酰胺化合物的分子。 吲哚衍生物由通式（1）表示：其中R 1表示用于烷基化DNA的官能团; R 2表示氢原子，烷基或酰基; X表示具有一个结构单元或具有两个或更多个可以相同或不同的结构单元的二价基团，其结构单元由下式表示：（其中m为0至10的整数），其中 结构单元，与R 2相邻的末端结构单元可以是由下式表示的结构单元：（其中k是0至10的整数）。

    Anti-obesity agent
    72.
    发明申请
    Anti-obesity agent 审中-公开
    抗肥胖剂

    公开(公告)号：US20060210659A1

    公开(公告)日：2006-09-21

    申请号：US11377795

    申请日：2006-03-16

    申请人： Isao Nadaoka ,  Hiroshi Sugiyama

    发明人： Isao Nadaoka ,  Hiroshi Sugiyama

    IPC分类号： A61K36/71 ,  A61K31/704 ,  A61K31/20

    CPC分类号： A61K31/704 ,  A21D13/80 ,  A23F3/163 ,  A23F5/243 ,  A23G3/36 ,  A23G4/06 ,  A23L2/02 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/20 ,  A61K36/71 ,  A61K2300/00 ,  A23V2250/21

    摘要： The object of the present invention is to provide an active substance which has an anti-obesity effect such as a triglyceride lowering activity, a cholesterol lowering activity and the like. The present invention provides a blood triglyceride lowering agent, a cholesterol lowering agent, a body fat storage suppressive agent, an anti-obesity agent and an antilipemic agent, characterized in that each of said agents comprises a cycloartane-type triterpene or glycoside thereof. Moreover, the present invention provides the use of a Black cohosh plant in order to prepare said agents. Further, the present invention provides a beverage, food and quasi-drug comprising said agents.

    摘要翻译： 本发明的目的是提供具有抗肥胖作用的活性物质，例如甘油三酯降低活性，降胆固醇活性等。 本发明提供了一种血液甘油三酸酯降低剂，降胆固醇剂，体脂储存抑制剂，抗肥胖剂和抗血脂剂，其特征在于，所述药物均包含环戊烷型三萜烯或其糖苷。 此外，本发明提供了一种黑咖啡植物以便制备所述药剂的用途。 此外，本发明提供了包含所述试剂的饮料，食品和准药物。

    Output apparatus and output method
    73.
    发明授权
    Output apparatus and output method 失效
    输出设备及输出方式

    公开(公告)号：US06278527B1

    公开(公告)日：2001-08-21

    申请号：US09002372

    申请日：1998-01-02

    申请人： Hiroyuki Maeda ,  Yuko Suga ,  Hiroshi Sugiyama ,  Akira Katayama ,  Akihiko Shimomura ,  Kazuhiro Nakajima

    发明人： Hiroyuki Maeda ,  Yuko Suga ,  Hiroshi Sugiyama ,  Akira Katayama ,  Akihiko Shimomura ,  Kazuhiro Nakajima

    IPC分类号： G06K1500

    CPC分类号： H04N1/00297 ,  G06K15/00 ,  G06K2215/0011 ,  G06K2215/0014 ,  G06K2215/0071 ,  H04N1/00283

    摘要： An output apparatus which produces the print output by saving in a first memory print data input via a two-way interface, and converting the print data into the print out information, comprising a second memory different from the first memory for saving the print data with a print ID number added which is input via the interface, a retrieving unit for retrieving corresponding print data of the second memory based on a print ID number input from the outside, and an output unit for outputting the retrieved print data converted into the print out information.

    摘要翻译： 一种输出装置，其通过保存经由双向接口输入的第一存储器打印数据并将打印数据转换为打印输出信息来产生打印输出，该打印输出装置包括与第一存储器不同的第二存储器，用于保存打印数据， 经由接口输入的打印ID号码，基于从外部输入的打印ID号来检索第二存储器的相应打印数据的检索单元，以及用于输出被转换成打印输出的检索到的打印数据的输出单元 信息。

    Electrophotographic photoreceptor
    74.
    发明授权
    Electrophotographic photoreceptor 有权
    电子照相感光体

    公开(公告)号：US6150065A

    公开(公告)日：2000-11-21

    申请号：US285712

    申请日：1999-04-05

    申请人： Tohru Kobayashi ,  Yoko Aoki ,  Mamoru Yamada ,  Yoshimasa Matsushima ,  Hiroshi Sugiyama ,  Toshimitsu Hagiwara ,  Hajime Suzuki

    发明人： Tohru Kobayashi ,  Yoko Aoki ,  Mamoru Yamada ,  Yoshimasa Matsushima ,  Hiroshi Sugiyama ,  Toshimitsu Hagiwara ,  Hajime Suzuki

    IPC分类号： G03G5/06 ,  G03G5/09

    CPC分类号： G03G5/0607 ,  G03G5/0672

    摘要： Disclosed is a charge transfer material which is highly soluble in a binder resin, does not precipitates crystals and produces no pinhole and also disclosed is an electrophotographic photoreceptor comprising the charge transfer material which comprises a butadiene compound represented by the formula (I): ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, respectively represent a lower alkyl group having 1-4 carbon atoms or a phenyl group or benzyl group which may have a substituent and R.sup.3, R.sup.4 and R.sup.5, which may be the same or different, respectively represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group having 1-4 carbon atoms or a halogen atom; and a butadiene compound represented by the general formula (II): ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same as above, and the content of the butadiene compound of the formula (I) is at least 60% by weight based on the total amount by weight of the butadiene compounds of the formulae (I) and (II).

    摘要翻译： 公开了一种高度可溶于粘合剂树脂的电荷转移材料，不会析出晶体并且不产生针孔，并且还公开了包含电荷转移材料的电子照相感光体，其包含由式（I）表示的丁二烯化合物：其中R1 和可以相同或不同的R 2分别表示可以具有取代基的具有1-4个碳原子的低级烷基或可以具有取代基的苯基或苄基，R 3，R 4和R 5可以相同或不同， 分别表示氢原子，卤素原子，低级烷基，具有1-4个碳原子的低级烷氧基或卤素原子; 和由通式（II）表示的丁二烯化合物：其中R1，R2，R3，R4和R5与上述相同，式（I）的丁二烯化合物的含量为至少60重量％ 关于式（I）和（II）的丁二烯化合物的总重量。

    Information recording apparatus
    76.
    发明授权
    Information recording apparatus 失效
    信息记录装置

    公开(公告)号：US5589858A

    公开(公告)日：1996-12-31

    申请号：US213998

    申请日：1994-03-15

    申请人： Hidejiro Kadowaki ,  Hiroshi Sugiyama ,  Yasuhiko Ishida ,  Makoto Takamiya

    发明人： Hidejiro Kadowaki ,  Hiroshi Sugiyama ,  Yasuhiko Ishida ,  Makoto Takamiya

    IPC分类号： B41J2/125 ,  B41J11/42 ,  B41J29/38

    CPC分类号： B41J2/125 ,  B41J11/42

    摘要： In an apparatus wherein a recording medium is conveyed by a conveying system with the front surface of the recording medium opposed to recording heads and information is recorded on the recording medium by liquid droplet jet, a first speed meter is provided on the back side of the recording medium and further, a second speed meter for detecting liquid droplet jet speed together with the first speed meter is provided at a predetermined location, whereby the recording position is adjusted. The first and second speed meters may preferably be optical Doppler velocimeters which will not cause any speed detection error with fluctuation of the wavelength of a light source.

    摘要翻译： 在记录介质由记录介质的前表面与记录头相对并通过液滴喷射记录在记录介质上的传送系统传送的设备中，在第一速度计 记录介质，并且在预定位置处设置用于与第一速度计一起检测液滴喷射速度的第二速度计，由此调节记录位置。 第一和第二速度计可以优选地是光学多普勒测速仪，其不会由于光源的波长的波动而引起任何速度检测误差。