摘要:
A brush seal assembly for turbo-engines is provided for sealing off spaces on a circumferential gap which are differently acted upon by pressure, particularly between an engine stator and an engine rotor. A holding device for a bristle bundle is provided on the engine stator, from which holding device the bristle bundle is guided between circumferential webs in a sealing manner against the engine rotor and forms an axial gap in the circumferential direction with respect to one web facing the high-pressure side. In this case, at least on the side which faces the space of the higher pressure on the seal, the bristle bundle is to have devices for the shielding against a turbulent flow triggered by the engine rotor.
摘要:
Primary and secondary amines in biological fluids are selectively derivitized by reaction with esters of N-hydroxysuccinimide or N-hydroxysulfosuccinimide to form an N-acylated derivative. Those N-acylated derivatives may then be extracted into a polar organic phase and extracted. Non-electroactive amines may be made suitable for coulometric analysis by selecting the ester used so as to attach an electroactive group to the amine. For example, histamine may be reacted with the Bolton-Hunter reagent to form a suitable derivative in high yield.
摘要:
A composite board with a multilayer laminated facer is presented having a nonwoven, a first polymer layer, and a second polymer layer. The laminate may be printed on the nonwoven, on the upper surface of the first polymer layer or inverted printed on the backside of an applied film. A number of configurations for the polymer layers are disclosed. The laminate may include exposed fibers on the lower surface or the nonwoven may be saturated. A removable peel-ply may be included. By controlling the placement and thickness of the polymer layers it is possible to tailor additive in the polymers such as colorants, opacifiers, UV stabilizers, and fire retardants to improve quality and reduce costs. In an alternate embodiment of the present invention, a first polymer layer is applied to the topside of the nonwoven and the second polymer is laminated to the first polymer layer as a preformed film. The laminated facer is thermally or adhesively bonded to the composite board.
摘要:
The present invention provides a laminate material having a polyester film and a layer of polyester fibers cohesively bonded thereto. Generally, a metal layer deposited at least one surface of the laminate. The invention may also include a glass reinforced polymer layer formed on the laminated facer where the polymer of the glass reinforced polymer layer is commingled with the nonwoven of the laminated facer. The laminate may further include a second polymer layer having a thickness joined to the fiber layer and/or a layer of hot melt adhesive applied to the polyester fibers. Also presented is a composite material having a polyester film, a layer of polyester fibers bonded to the second polymer layer; a second polymer layer joined to the polyester film; and a glass reinforced polymer layer formed on the laminated facer, where the polymer of the glass reinforced polymer layer is commingled with the nonwoven of the laminated facer.
摘要:
The present invention relates to a network based, third-party beneficiary donation system, and in particular to systems and methods that allow a merchant to provide a choice to participating consumer(s) in the form of donations to third party beneficiaries based on consumer purchases wherein the consumer chooses their third party beneficiary from a merchant curated list or customer self-generated list and independently determines the percentage amount of the donation or selects a pre-determined amount. In this manner, consumers are provided with an option to purchase products from the authorized merchant knowing that the product purchases may result in a specified donation to a customer selected third-party beneficiary or multiple customer selected third party beneficiaries on a per product or per order basis. Third party beneficiaries are generally intended to be charities or causes but are not required to have tax-exempt status.
摘要:
The invention encompasses a novel class of diaryl ether derivatives which inhibit the processing of APP by the putative γ-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included.
摘要:
A medical device for example a wound dressing having antibacterial and optionally, antifungal properties, are provided together with methods for making the device. An exemplary dressing includes a layer of silver-containing fabric, (optionally) a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.
摘要:
A device for determining material properties includes a bottom panel extending from a first end to a second end of the device, for supporting a material to be tested. A closed loop flexible wall extends upwardly from the panel and is in operational engagement with a flexible wall idle means towards the first end of the device and a flexible wall driving means in spaced relation with the flexible wall idle means. The flexible wall driving means causes movement of the closed loop flexible wall along a predetermined closed loop path. The flexible wall driving means and the means of driving it are arranged at a position outside of a material containment area of the device.
摘要:
A self-aligning fairlead latch device is provided for guiding and securing an anchor chain between an offshore structure and an anchor. The fairlead latch device includes a latch housing pivotally mounted to a fairlead housing. The latch housing includes one or more latches for securing the anchor chain in place. The fairlead latch device further includes an upper retainer component that is coupled to an upper support structure and a lower support structure. The coupling of the upper retainer component to the support structures allow the fairlead latch device to be relocated by lifting of the device from the support structures.
摘要:
The present invention relates to a novel class of substituted spirocyclic compounds, represented by the following structural Formula: I Wherein A, B and D are independently selected from CR12, NR1a, C(O) and O; E is selected from a bond, CR12, NR1a, C(O) and O; wherein at least one of A, B, D or E is CR12; and provided that when A is O, then E is not O; G is CR12; R is selected from NH2 and OH; These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing termin differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo.