摘要:
To provide the compounds inhibiting PDE 7 selectively, and therefore, enhance cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic disease, inflammatory disease or immunologic disease. The compound is pyridinylpyrazolopyrimidinone compound represented by the following formula (IA) or (IB): especially, R1 is cyclohexyl or cycloheptyl group, R2 is methyl; R3 is a group: —NR5R6 or —S(O)0-2R8; hydrogen atom; nitro group; cyano group; a halogen atom; heteroaryl group; and R4 is methoxy or ethoxy group.
摘要翻译:选择性地提供抑制PDE 7的化合物,从而提高细胞cAMP水平。 因此,该化合物可用于治疗各种疾病如过敏性疾病,炎性疾病或免疫疾病。 化合物是由下式(IA)或(IB)表示的吡啶基吡唑并嘧啶酮化合物:特别地,R 1是环己基或环庚基,R 2是甲基; R 3是一个基团:-NR 5 R 6或-S(O)0-2 R 10, SUP> 8 SUP> 氢原子; 硝基; 氰基; 卤素原子; 杂芳基; R 4是甲氧基或乙氧基。
摘要:
A label position where a label is to be recorded is determined. Information of digital contents is recorded by a normal method at a position other than the label position on the information recording surface of a disc. On the other hand, information of the label is recorded at the label position on the information recording surface of the disc by modulating that information such that its visual pattern is different from that at a position other than the label position. Also, the information of the digital contents is recorded together in this label position.
摘要:
A method for adjusting a voltage control type oscillator prevent changes in characteristics from occurring after adjustments and permits the oscillator to be produced at a low cost. The voltage control type oscillator includes a strip electrode provided on a first surface of a dielectric substrate and a ground electrode provided on a second surface of the dielectric substrate. The strip electrode and the ground electrode constitute a microstrip line resonator. In addition to the resonator, electric components are mounted on the first surface of the dielectric substrate. A case is attached to the dielectric substrate such that the case covers the strip electrode and the electronic components. After attaching the case, the strip electrode is trimmed by irradiating a laser beam from the second surface side of the dielectric substrate.
摘要:
The present invention provides an image forming apparatus that has unfixed image forming device for forming an unfixed image based on an image formation start signal, and fixing device for fixing the unfixed image, formed by the unfixed image forming device, on a recording material, wherein the fixing device includes a rotating member and magnetic flux generating device for generating a magnetic flux by supplying power, wherein the magnetic flux generated by the magnetic flux generating device generates an eddy current in the rotating member, so that the rotating member generates heat, thereby an image on the recording material is heated, and wherein, in a stand-by state prior to an input of the image formation start signal, a rotation of the rotating member is stopped and the magnetic flux generating device is energized.
摘要:
This invention prepares two control voltage to be input to a VCO circuit. The first control voltage is used to continuously change the oscillation frequency of the VCO circuit. The second control voltage is used to continuously change the first control voltage/oscillation frequency characteristics. The invention also includes a phase detecting circuit for comparing the phase of the data read from a disk with that of the output from the voltage-controlled oscillator, a frequency detecting circuit for comparing the frequency of the data read from the disk with that of the output from the voltage-controlled oscillator, a first filter circuit for equalizing signals representing the detection results obtained by the phase detecting circuit and the frequency detecting circuit, and a second filter circuit for extracting only a low-frequency component from the output from the first filter circuit. The output from the first filter circuit is used as the first control voltage. The output from the second filter circuit is used as the second control voltage. The second control voltage is changed to always keep the first control voltage at a predetermined voltage.
摘要:
The present invention relates to an image heating apparatus, in which an end of a first magnetic portion and an end of a second magnetic portion are present within a width along a recording material moving direction of a nip, and a width of a gap along a recording material moving direction is different with respect to a direction which is orthogonal to the recording material moving direction.
摘要:
An apparatus and a signal processing circuit for reproducing data stored on a disc to prevent a buffer memory from experiencing overflow/underflow, and/or to reduce power consumption in a digital-to-analog converter. When the data to be read is ROM data, reading from the buffer memory is conducted in response to a varying frame clock signal, and the frequency of a reference clock signal to the digital-to-analog converter is reduced.
摘要:
A prophylactic or therapeutic agent for malignant hypercalcemia, bone Paget's disease and osteoporosis is disclosed, which contains as an active ingredient a dipeptide derivative represented by formula:R.sup.1 NH--CH(R.sup.2)--CO--NH--CH(R.sup.3)--R.sup.4 (I)wherein R.sup.1 represents an aliphatic acyl group, a halogen-substituted aliphatic acyl group, or benzyloxycarbonyl group; R.sup.2 represents a lower alkyl group or an aralkyl group; R.sup.3 represents a lower alkyl group, an aralkyl group, or methylthioethyl group; R.sup.4 represents formyl group, an aliphatic acyl group, an aliphatic acyl group substituted with a halogen atom or a lower alkoxycarbonyl group, a di-lower alkoxymethyl group, a diacyloxymethyl group, a lower alkoxalyl group, a 1-hydroxy-2-lower alkoxycarbonylethyl group, a halogen-substituted 1-hydroxy-2-lower alkoxycarbonylethyl group, hydroxyiminomethyl group, ureidoiminomethyl group, benzimidazol-2-yl group, or a group: ##STR1## wherein A and B, which may be the same or different, each represents O, S, NH; and n represents 2 or 3; provided that R.sup.4 is not a formyl group when R.sup.3 is an n-butyl group.
摘要:
The present electronic typewriter executes a spelling check control and, more specifically, judges whether or not a word in a dictionary memory identical to an inputted word exists. If a word does not exists, the word printing operation or sweep display of this word is automatically interrupted by a central processing unit. The present invention further provides an electronic typewriter wherein the operator is freed of the spelling check task and high-speed key-in operation can be achieved by preventing misspelled words from being printed.
摘要:
An electronic typewriter, comprising: (a) a keyboard (2) generating a signal corresponding to a depressed key and comprising at least a plurality of character keys (5) for inputting character data, a space key (4) for separating said character data into words and a release key (6), a dictionary memory (12) for storing a plurality of words, a working memory (13) for sequentially storing said plurality of words, a spelling check control means (11) for reading out word data from said dictionary memory (12) as well as said plurality of words inputted via said keyboard, comparing the spelling of said words with said word data, and judging whether or not the spelling of said words is correct, means for disabling said spelling check control means (11), said means disabling said spelling check control means (11) only for a first word inputted after the depression of said release key (6) of said keyboard (2), and visible outputting means (8), (9) for outputting input data visibly.