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    MOTION-BASED OPTIMIZATION FOR PLACEMENT OF CARDIAC STIMULATION ELECTRODES
    71.
    发明申请
    MOTION-BASED OPTIMIZATION FOR PLACEMENT OF CARDIAC STIMULATION ELECTRODES 有权
    基于运动的优化用于放置心脏刺激电极

    公开(公告)号：US20120165643A1

    公开(公告)日：2012-06-28

    申请号：US13416211

    申请日：2012-03-09

    申请人： Michael Yang ,  Euljoon Park ,  Kyungmoo Ryu ,  Stuart Rosenberg ,  Michael J. Coyle

    发明人： Michael Yang ,  Euljoon Park ,  Kyungmoo Ryu ,  Stuart Rosenberg ,  Michael J. Coyle

    IPC分类号： A61B5/042

    CPC分类号： A61N1/056 ,  A61B5/0422 ,  A61B5/06 ,  A61N1/3627 ,  A61N1/36578 ,  A61N1/3684 ,  A61N2001/0585

    摘要： An exemplary method includes use of a multielectrode device that can help position a cardiac stimulation lead to an optimal site in the heart based at least in part on cardiac motion information acquired via the multielectrode device and one or more pairs of current delivery electrodes that establish potential fields (e.g., for use as a coordinate system). An exemplary mutlielectrode device may be a multielectrode catheter or a multifilar, electrode-bearing guidewire. Various other exemplary methods, devices, systems, etc., are also disclosed.

    摘要翻译： 一种示例性方法包括使用多电极装置，该多电极装置能够至少部分地基于通过多电极装置获得的心脏运动信息和建立潜在的一对或多对电流输送电极来帮助将心脏刺激引导到心脏中的最佳位置 字段（例如，用作坐标系）。 示例性的聚电极装置可以是多电极导管或多针，电极轴承导丝。 还公开了各种其它示例性方法，装置，系统等。

    Method and system for identifying cardiac arrhythmia driver sites
    72.
    发明申请
    Method and system for identifying cardiac arrhythmia driver sites 有权
    识别心律失常司机场所的方法和系统

    公开(公告)号：US20120089038A1

    公开(公告)日：2012-04-12

    申请号：US12923769

    申请日：2010-10-07

    申请人： Kyungmoo Ryu ,  Valtino X. Afonso

    发明人： Kyungmoo Ryu ,  Valtino X. Afonso

    IPC分类号： A61B5/0452 ,  A61N1/365

    CPC分类号： A61B5/0452 ,  A61B5/046 ,  A61N1/3624

    摘要： A method of identifying potential driver sites for cardiac arrhythmias includes acquiring a plurality of electrograms from a plurality of locations on at least a portion of a patient's heart. Using the acquired electrograms, at least one electrical activity map is generated. Desirable electrical activity maps include complex fractionated electrogram standard deviation and mean maps, dominant frequency maps, peak-to-peak voltage maps, and activation sequence maps. Using one or more of these maps (e.g., by analyzing one or more electrogram morphological characteristics represented by these maps), at least one potential driver site can be detected.

    摘要翻译： 识别用于心律失常的潜在驾驶员位置的方法包括从患者心脏的至少一部分上的多个位置获取多个电描记图。 使用所获取的电描记图，生成至少一个电活动图。 期望的电活动图包括复杂的分级电描记图标准偏差和平均图，主要频率图，峰 - 峰电压图和激活序列图。 使用这些图中的一个或多个（例如，通过分析由这些图表示的一个或多个电描记图形态特征），可以检测至少一个潜在的驾驶员位置。

    Methods and Systems for Filtering Respiration Noise from Localization Data
    73.
    发明申请
    Methods and Systems for Filtering Respiration Noise from Localization Data 有权
    从定位数据过滤呼吸噪声的方法和系统

    公开(公告)号：US20120016253A1

    公开(公告)日：2012-01-19

    申请号：US12835518

    申请日：2010-07-13

    申请人： Steve Koh ,  Stuart Rosenberg ,  Kyungmoo Ryu

    发明人： Steve Koh ,  Stuart Rosenberg ,  Kyungmoo Ryu

    IPC分类号： A61B5/08

    CPC分类号： A61B5/063 ,  A61B5/113 ,  A61B5/721 ,  A61B90/36 ,  A61B2017/00053 ,  A61B2034/2048 ,  A61B2034/2051 ,  A61B2034/2053 ,  A61B2562/0219

    摘要： A method of filtering respiration noise from a localization signal includes acquiring a localization signal from at least one position measurement sensor within a localization field and acquiring an acceleration signal for at least one localization field generator (e.g., a patch electrode). A displacement signal for the field generator is calculated, for example by integrating the acceleration signal twice, and transformed into the frequency domain in order to calculate a fractional power indicative of patient respiration. The fractional power can then be compared to a threshold value, and the localization signal can be filtered if the fractional power exceeds the threshold value. Alternatively, the acquired acceleration signal can be used to gate collection of data points from the localization signal.

    摘要翻译： 从定位信号过滤呼吸噪声的方法包括从定位场内的至少一个位置测量传感器获取定位信号，并获取至少一个定位场发生器（例如，贴片电极）的加速度信号。 计算场发生器的位移信号，例如通过对加速度信号进行两次积分，并将其变换到频域以便计算指示患者呼吸的分数功率。 然后可以将分数功率与阈值进行比较，如果分数功率超过阈值，则可以对定位信号进行滤波。 或者，获取的加速度信号可以用于从定位信号门控收集数据点。

    Method and system for identifying cardiac arrhythmia driver sites
    78.
    发明授权
    Method and system for identifying cardiac arrhythmia driver sites 有权

    公开(公告)号：US08340766B2

    公开(公告)日：2012-12-25

    申请号：US12923769

    申请日：2010-10-07

    申请人： Kyungmoo Ryu ,  Valtino X. Afonso

    发明人： Kyungmoo Ryu ,  Valtino X. Afonso

    IPC分类号： A61N1/365

    CPC分类号： A61B5/0452 ,  A61B5/046 ,  A61N1/3624

    摘要： A method of identifying potential driver sites for cardiac arrhythmias includes acquiring a plurality of electrograms from a plurality of locations on at least a portion of a patient's heart. Using the acquired electrograms, at least one electrical activity map is generated. Desirable electrical activity maps include complex fractionated electrogram standard deviation and mean maps, dominant frequency maps, peak-to-peak voltage maps, and activation sequence maps. Using one or more of these maps (e.g., by analyzing one or more electrogram morphological characteristics represented by these maps), at least one potential driver site can be detected.

    System and Method for ATP Treatment Utilizing Multi-Electrode Left Ventricular Lead
    79.
    发明申请
    System and Method for ATP Treatment Utilizing Multi-Electrode Left Ventricular Lead 审中-公开
    使用多电极左心室铅的ATP治疗的系统和方法

    公开(公告)号：US20120191154A1

    公开(公告)日：2012-07-26

    申请号：US13012574

    申请日：2011-01-24

    申请人： Kyungmoo Ryu ,  Stuart Rosenberg ,  Allen Keel ,  Taraneh Ghaffari Farazi ,  Richard Williamson ,  Mark Carlson

    发明人： Kyungmoo Ryu ,  Stuart Rosenberg ,  Allen Keel ,  Taraneh Ghaffari Farazi ,  Richard Williamson ,  Mark Carlson

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36521 ,  A61N1/3622 ,  A61N1/3684 ,  A61N1/3686 ,  A61N1/3962

    摘要： An implantable medical device includes a lead configured to be located proximate to the left ventricle (LV) of the heart, the lead including multiple LV electrodes to sense cardiac activity at multiple LV sensing sites. The a detection module to detect an arrhythmia that represents at least one of a tachycardia and fibrillation based at least in part on the cardiac activity sensed at the multiple LV sensing sites. The ATP therapy module to identify at least one of an ATP configuration or an ATP therapy site based on the cardiac sensed activity at the LV sensing sites, the ATP therapy module to control delivery of antitachycardia pacing (ATP) therapy at the ATP therapy site. The ATP therapy module delivers a stimulus to electrodes at one or more of an LV site, right ventricular (RV) site and right atrial (RA) site, the detection module to sense evoked responses at the LV sensing sites, the ATP therapy module to designate the ATP therapy site to include at least the LV sensing site with a shortest activation time relative to the one or more LV site, RV site and RA site where the stimulus is delivered.

    摘要翻译： 可植入医疗装置包括被配置为位于心脏左心室（LV）附近的引线，该引线包括多个LV电极以感测多个LV感测部位的心脏活动。 该检测模块至少部分地基于在多个LV感测位点处感测到的心脏活动来检测代表心动过速和颤动中的至少一种的心律失常。 ATP治疗模块基于LV感测位点处的心脏感测活动来鉴定ATP配置或ATP治疗部位中的至少一个，ATP治疗模块用于控制ATP治疗部位的抗心动过速起搏（ATP）治疗的递送。 ATP治疗模块向LV位点，右心室（RV）位点和右心房（RA）位点的一个或多个处的电极施加刺激，检测模块用于感测LV感测位点处的诱发反应，ATP治疗模块 指定ATP治疗部位至少包括相对于传递刺激物的一个或多个LV部位，RV部位和RA部位具有最短激活时间的LV感测部位。