公开(公告)号：US07432091B2

公开(公告)日：2008-10-07

申请号：US10546210

申请日：2004-02-23

申请人： Hideaki Yukawa ,  Noriyuki Yamamoto

发明人： Hideaki Yukawa ,  Noriyuki Yamamoto

IPC分类号： C12P3/00 ,  H01M8/18

CPC分类号： C12P3/00

摘要： It is intended to obtain anaerobic microbial cells in an amount sufficient for hydrogen generation reaction, impart a hydrogen generation function to an aerobic microorganism within a short time and provide an industrial advantageous method of producing hydrogen.The above object can be established by providing a highly efficient microbial hydrogen production method characterized by comprising culturing a microorganism having a formate dehydrogenase gene and a hydrogenase gene under aerobic conditions, culturing the resulting microbial cells under anaerobic conditions in a liquid culture medium containing a formic acid compound, and then using the thus obtained cells for hydrogen generation.

摘要翻译： 旨在获得足够的氢生成反应的厌氧微生物细胞，在短时间内向需氧微生物赋予氢生成功能，并提供工业上有利的氢生产方法。 上述目的可以通过提供一种高效微生物氢生产方法来建立，其特征在于包括在需氧条件下培养具有甲酸脱氢酶基因和氢化酶基因的微生物，在厌氧条件下在含有甲酸的液体培养基中培养所得微生物细胞 酸化合物，然后使用如此获得的电池进行氢气生成。

公开(公告)号：US07258938B2

公开(公告)日：2007-08-21

申请号：US10087994

申请日：2002-03-05

申请人： Noriyuki Yamamoto ,  Nobuo Katoh ,  Hideaki Yukawa

发明人： Noriyuki Yamamoto ,  Nobuo Katoh ,  Hideaki Yukawa

IPC分类号： H01M8/06 ,  H01M8/16

CPC分类号： H01M8/0612 ,  H01M8/1009 ,  H01M8/16 ,  Y02E60/527

摘要： A polymer electrolyte fuel cell includes a housing provided with an anode-side supply inlet for supplying a material for fuel, an anode and a cathode accommodated in the housing to sandwich a polymer electrolyte membrane, and a layer containing a biochemical catalyst which decomposes the material for fuel to generate fuel, the layer being formed between the anode-side supply inlet and the anode.

公开(公告)号：US20050221353A1

公开(公告)日：2005-10-06

申请号：US11059468

申请日：2005-02-16

申请人： Ayako Fujisaki ,  Noriyuki Yamamoto ,  Atsushi Mori ,  Daisuke Sakurai ,  Iwao Yamashita ,  Takahiko Kasuga

发明人： Ayako Fujisaki ,  Noriyuki Yamamoto ,  Atsushi Mori ,  Daisuke Sakurai ,  Iwao Yamashita ,  Takahiko Kasuga

IPC分类号： C12Q1/68 ,  G06F19/00 ,  G06F19/18 ,  G06F19/22 ,  G01N33/48 ,  G01N33/50

CPC分类号： G16B45/00 ,  G16B25/00 ,  G16B30/00 ,  G16B50/00

摘要： In gene expression analysis using DNA chips, the position of a probe on a genome sequence, candidates for splice variants, and the like are displayed in relation to one another. Information on the position of the probe designed for a DNA chip system on the genome sequence is retrieved by connecting to an external database and a server that manage sequence information (genome sequence, mRNA, EST, etc.) and annotation information of various organisms. Further, homologous sequences of a gene for which the probe was designed are detected by homology search program, and the candidates for splice variants obtained from the search are stored in a DNA chip database in relation to expression data.

摘要翻译： 在使用DNA芯片的基因表达分析中，探针在基因组序列上的位置，剪接变体的候选等相互显示。 通过连接到管理各种生物体的序列信息（基因组序列，mRNA，EST等）和注释信息的外部数据库和服务器来检索针对基因组序列上的DNA芯片系统设计的探针的位置的信息。 此外，通过同源性检索程序检测设计探针的基因的同源序列，将从搜索获得的剪接变体的候选物存储在DNA芯片数据库中，与表达数据相关。

公开(公告)号：US06911443B2

公开(公告)日：2005-06-28

申请号：US10258628

申请日：2001-04-17

申请人： Takeshi Yura ,  Arnel B. Concepcion ,  Gyoonhee Han ,  Makiko Marumo ,  Hiroko Yoshino ,  Norihiro Kawamura ,  Toshio Kokubo ,  Hiroshi Komura ,  Yingfu Li ,  Timothy B. Lowinger ,  Muneto Mogi ,  Noriyuki Yamamoto ,  Nagahiro Yoshida ,  Scott Miller ,  Margaret A. Popp ,  Aniko M. Redmann ,  Martha E. Rodriguez ,  William J. Scott ,  Ming Wang

发明人： Takeshi Yura ,  Arnel B. Concepcion ,  Gyoonhee Han ,  Makiko Marumo ,  Hiroko Yoshino ,  Norihiro Kawamura ,  Toshio Kokubo ,  Hiroshi Komura ,  Yingfu Li ,  Timothy B. Lowinger ,  Muneto Mogi ,  Noriyuki Yamamoto ,  Nagahiro Yoshida ,  Scott Miller ,  Margaret A. Popp ,  Aniko M. Redmann ,  Martha E. Rodriguez ,  William J. Scott ,  Ming Wang

IPC分类号： A61K31/505 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/541 ,  A61P1/04 ,  A61P3/04 ,  A61P7/02 ,  A61P7/06 ,  A61P11/02 ,  A61P11/06 ,  A61P17/00 ,  A61P17/04 ,  A61P17/06 ,  A61P19/02 ,  A61P21/04 ,  A61P25/28 ,  A61P27/02 ,  A61P27/14 ,  A61P29/00 ,  A61P35/00 ,  A61P37/02 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  C07D487/04 ,  C07D519/00 ,  C07D417/10

CPC分类号： C07D487/04

摘要： A compound of the formula (I) in which R1 is —OR11, —SR11, —SOR11, —SO2R11, —NHR11, or —NR12R13 , and R11, R12, and R13 are as defined broadly in the text. R2 is H, C1-C6alkyl, carbamoyl, or an ester group. R3 is thienyl, pyridyl optionally substituted by halogen or C1-C6alkoxy; naphthyl optionally substituted by C1-C6alkoxy; dioxane fused phenyl; dioxacyclopentane fused phenyl; or optionally substituted phenyl. Y is CH or N. A process for preparing such compounds, pharmaceutical compositions containing such compounds, and a method of treating asthma using them are also disclosed and claimed.

摘要翻译： 其中R 1为-OR 11，-SR 11，-SOR 11的式（I）化合物， SO 2，-SO 2，R 11，-NHR 11或-NR 12 R 13 ＆lt; / SUP＆gt;和R 11，R 12和R 13如在文中广义地定义的。 R 2是H，C 1 -C 6烷基，氨基甲酰基或酯基。 R 3是噻吩基，任选被卤素或C 1 -C 6烷氧基取代的吡啶基; 任选被C 1 -C 6烷氧基取代的萘基; 二恶烷稠合苯基; 二氧杂环戊烷稠合苯基; 或任选取代的苯基。 Y是CH或N.一种制备这种化合物的方法，含有这些化合物的药物组合物和使用它们治疗哮喘的方法也被公开和要求保护。

公开(公告)号：US06731865B1

公开(公告)日：2004-05-04

申请号：US09438353

申请日：1999-11-11

申请人： Noriyuki Yamamoto

发明人： Noriyuki Yamamoto

IPC分类号： H04N5781

CPC分类号： H04N21/4425 ,  G11B20/10 ,  G11B20/18 ,  G11B27/034 ,  G11B27/105 ,  G11B27/329 ,  G11B2020/10916 ,  G11B2020/183 ,  G11B2220/20 ,  H04N5/76 ,  H04N5/781 ,  H04N21/4325

摘要： A recording/playback apparatus, includes a supplying device for supplying continuous data at a predetermined transfer rate. A recording device having a certain seek performance and recording mode records the continuous data on the recording medium in a recording unit, and a first setting device sets the size of the recording unit according to the transfer rate of the supplied continuous data or the seek performance of the recording device or the recording mode. The recording device includes a designating device for designating the transfer rate according to the recording mode. The apparatus further comprises a second setting device for setting the number of allowable retries to play back data from said recording medium according to the transfer rate or the seek performance or the recording unit size.

摘要翻译： 记录/重放装置包括用于以预定传送速率提供连续数据的供应装置。 具有一定寻找性能和记录模式的记录装置将记录介质上的连续数据记录在记录单元中，并且第一设置装置根据所提供的连续数据或寻找性能的传送速率来设置记录单元的尺寸 的记录装置或记录模式。 记录装置包括用于根据记录模式指定传送速率的指定装置。 该装置还包括第二设置装置，用于根据传送速率或搜索性能或记录单元尺寸设置允许重试次数从所述记录介质播放数据。

公开(公告)号：US06362521B1

公开(公告)日：2002-03-26

申请号：US09427997

申请日：1999-10-27

申请人： Yasuhiro Nabika ,  Tetsukazu Okamoto ,  Toshiharu Hirota ,  Noriyuki Yamamoto

发明人： Yasuhiro Nabika ,  Tetsukazu Okamoto ,  Toshiharu Hirota ,  Noriyuki Yamamoto

IPC分类号： H01L23053

CPC分类号： C04B35/465 ,  C04B35/4684

摘要： A semiconductor ceramic composed of barium titanate, lead titanate, strontium titanate, and calcium titanate as primary components, includes samarium oxide as a semiconductor-forming agent in the primary components, and the average diameter of crystalline particles of the semiconductor ceramic is about 7 to 12 &mgr;m. The semiconductor ceramic has a resistivity at room temperature not greater than 3.5 &OHgr;cm, a withstand voltage not less than 50 V/mm, a resistance-temperature coefficient &agr;10-100 not less than 9%/°C. and also has less variability of resistance.

摘要翻译： 由钛酸钡，钛酸铅，钛酸锶和钛酸钙作为主要成分构成的半导体陶瓷在主要成分中包含作为半导体形成剂的氧化钐，半导体陶瓷的结晶粒子的平均直径为约7〜 12个妈妈 半导体陶瓷在室温下的电阻率不大于3.5欧姆·厘米，耐压不低于50V / mm，电阻温度系数α10-100不低于9％/℃。 并且电阻的变异性也较小。

公开(公告)号：US06346496B2

公开(公告)日：2002-02-12

申请号：US09360313

申请日：1999-07-23

申请人： Yasuhiro Nabika ,  Tetsukazu Okamoto ,  Toshiharu Hirota ,  Noriyuki Yamamoto

发明人： Yasuhiro Nabika ,  Tetsukazu Okamoto ,  Toshiharu Hirota ,  Noriyuki Yamamoto

IPC分类号： C04B35468

CPC分类号： H01C7/025 ,  H01C17/30

摘要： A ceramic for the PTC thermistor having a resistivity at room temperature of 5 &OHgr;·cm or less, static withstanding voltage of 60 V/mm or more and temperature resistance coefficient of 9.0 %/° C., having small dispersion of the resistance, is composed of principal components of about 30 to 97 mol % of BaTiO3, about 1 to 50 mol % of PbTiO3, about 1 to 30 mol % of SrTiO3 and about 1 to 25 mol % of CaTiO3 (the total content of them being 100 mol %), as well as about 0.1 to 0.3 mole of Sm, about 0.01 to 0.03 mole of Mn and 0 to about 2.0 mole of Si relative to 100 moles of the principal components, the composite material being preferably heat-treated in an oxidative atmosphere after being fired in a reducing or neutral atmosphere for obtaining the ceramic.

摘要翻译： 在室温下具有5欧姆·厘米或更小的电阻率的PTC热敏电阻陶瓷，静电耐受电压为60V / mm以上，耐电阻系数为9.0％/℃，电阻分散小，为 由BaTiO 3的约30〜97摩尔％，PbTiO 3的1〜50摩尔％，SrTiO 3的1〜30摩尔％，CaTiO 3的1〜25摩尔％的主成分（其总量为100摩尔％ ），以及约0.1〜0.3摩尔的Sm，约0.01〜0.03摩尔的Mn和0〜约2.0摩尔的Si相对于100摩尔的主要成分，该复合材料优选在氧化气氛中经过热处理 在还原或中性气氛中烧制以获得陶瓷。

公开(公告)号：US6058084A

公开(公告)日：2000-05-02

申请号：US945333

申请日：1998-01-08

申请人： Noriyuki Yamamoto ,  Takamichi Yamakoshi

发明人： Noriyuki Yamamoto ,  Takamichi Yamakoshi

IPC分类号： G11B19/04 ,  G11B20/10 ,  G11B20/12 ,  G11B27/19 ,  G11B27/24 ,  G11B27/30 ,  G11B5/09 ,  G11B5/596

CPC分类号： G11B27/3027 ,  G11B19/04 ,  G11B20/10 ,  G11B20/1251 ,  G11B27/19 ,  G11B27/24 ,  G11B2020/1234 ,  G11B2020/1265 ,  G11B2020/1267 ,  G11B2020/1287 ,  G11B2220/20 ,  G11B2220/2516

摘要： The present invention relates to a disk unit or the like capable of improving the reliability of a sector ID-less system and performing rapid frame synchronization. A disk 101 has a plurality of segments (frames) extending in the direction of rotation thereof, each of which has servo regions for recording servo information and data regions for recording user data. A segment ID 105 is recorded in an address region in each servo region in the segment proportions of four to one. The segment ID is a code having information about frame numbers (segment numbers) as viewed from the position of origin and recorded with CRC added thereto. Owing to the detection of the segment ID 105 on the disk 101, the disk unit can rapidly establish frame synchronization, e.g., restrain a reduction in transfer rate used when, for example, data is recorded on both surfaces and reproduced therefrom. Even upon writing, the disk unit can detect out-of-frame synchronization, using the segment ID 105 and shift to an urgent write inhibiting process. Further, erroneous writing developed in the sector ID-less system can be avoided promptly.

摘要翻译： PCT No.PCT / JP97 / 00569 Sec。 371日期1998年1月8日 102（e）日期1998年1月8日PCT提交1997年2月27日PCT公布。 公开号WO97 / 32306 PCT 日期：1997年9月4日本发明涉及能够提高扇区无ID系统的可靠性并进行快速帧同步的盘单元等。 盘101具有沿其旋转方向延伸的多个段（帧），每个段具有用于记录伺服信息的伺服区域和用于记录用户数据的数据区域。 段ID 105被记录在每个伺服区域的地址区域中，以4比1的段比例。 片段ID是具有关于从原点位置观察的关于帧号（段号）的信息的代码并且被添加到其中的CRC记录的代码。 由于检测到盘101上的段ID105，因此盘单元可以快速建立帧同步，例如，当例如数据被记录在两个表面上并从其再现时，例如抑制所使用的传输速率的降低。 即使在写入时，盘单元也可以使用段ID 105检测帧外同步，并转移到紧急写入禁止进程。 此外，可以及时避免在扇区无ID系统中开发的错误写入。

公开(公告)号：US09212158B2

公开(公告)日：2015-12-15

申请号：US13537980

申请日：2012-06-29

申请人： Tatsuya Matsukawa ,  Noriyuki Yamamoto

发明人： Tatsuya Matsukawa ,  Noriyuki Yamamoto

IPC分类号： C07D317/30 ,  C07C405/00 ,  C07F7/18

CPC分类号： C07D317/30 ,  C07C405/00 ,  C07C2601/08 ,  C07F7/1804

摘要： A method for manufacturing a fatty acid derivative represented by formula (I) is provided: wherein Z1 is wherein R3 and R4 are hydrogen atom, halogen atom, lower alkyl or lower alkoxy; when R3 and R4 are lower alkoxy, R3 and R4 may be linked together to form a ring structure; which includes the step of reacting a compound of formula (II): wherein Z2 is the same as Z1; with a co-oxidizer under the presence of an azaadamantane-N-oxyl derivative.

摘要翻译： 提供了制备由式（I）表示的脂肪酸衍生物的方法：其中Z1是R3和R4是氢原子，卤素原子，低级烷基或低级烷氧基; 当R3和R4是低级烷氧基时，R3和R4可以连接在一起形成环结构; 其包括使式（II）化合物：其中Z2与Z1相同的步骤; 与共氧化剂在氮杂金刚烷-N-氧基衍生物存在下反应。

公开(公告)号：US20100137361A1

公开(公告)日：2010-06-03

申请号：US12700417

申请日：2010-02-04

申请人： Axel BOUCHON ,  Nicole Diedrichs ,  Achim Hermann ,  Klemens Lustig ,  Heinrich Meier ,  Josef Pernerstorfer ,  Elke Reissmüller ,  Muneto Mogi ,  Hiroshi Fujishima ,  Masaomi Tajimi ,  Noriyuki Yamamoto

发明人： Axel BOUCHON ,  Nicole Diedrichs ,  Achim Hermann ,  Klemens Lustig ,  Heinrich Meier ,  Josef Pernerstorfer ,  Elke Reissmüller ,  Muneto Mogi ,  Hiroshi Fujishima ,  Masaomi Tajimi ,  Noriyuki Yamamoto

IPC分类号： A61K31/47 ,  A61P11/06 ,  A61P13/02

CPC分类号： C07D215/38

摘要： This invention relates to tetrahydro-quinolinylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations.The tetrahydro-quinolinylurea derivative of the present invention has vanilloid receptor (VR1) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor overactivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).

摘要翻译： 本发明涉及可用作药物制剂活性成分的四氢 - 喹啉基脲衍生物及其盐。 本发明的四氢 - 喹啉基脲衍生物具有香草素受体（VR1）拮抗活性，可用于预防和治疗与VR1活性有关的疾病，特别是用于治疗泌尿系统疾病或障碍，例如逼尿肌过度活动 膀胱过度活动），尿失禁，神经源性逼尿肌过度活动（逼尿肌hyperflexia），特发性逼尿肌过度活动（逼尿肌不稳定），良性前列腺增生和下尿路症状; 慢性疼痛，神经性疼痛，术后疼痛，类风湿性关节炎疼痛，神经痛，神经病，痛觉，神经损伤，局部缺血，神经变性，中风和炎性疾病如哮喘和慢性阻塞性肺（或气道）疾病（COPD）。