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公开(公告)号：US5593972A
公开(公告)日：1997-01-14
申请号：US125012
申请日：1993-09-21
Applicant: David B. Weiner , William V. Williams , Bin Wang
Inventor： David B. Weiner , William V. Williams , Bin Wang
CPC classification number: C07K14/005 , A61K39/00 , A61K39/12 , A61K39/21 , C12N15/87 , A61K2039/53 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16222 , C12N2740/16234 , C12N2740/16322 , C12N2740/16334 , Y10S435/975 , Y10S514/818
Abstract: Methods of prophylactic and therapeutic immunization of an individual against pathogen infection, diseases associated with hyperproliferative cells and autoimmune diseases are disclosed. The methods comprise the steps of administering to cells of an individual, a nucleic acid molecule that comprises a nucleotide sequence that encodes a protein which comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen, a hyperproliferative cell associated protein or a protein associated with autoimmune disease respectively. In each case, nucleotide sequence is operably linked to regulatory sequences to enable expression in the cells. The nucleic acid molecule is free of viral particles and capable of being expressed in said cells. The cells may be contacted cells with a cell stimulating agent. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.
Abstract translation: 公开了个体对病原体感染的预防和治疗免疫的方法，与过度增殖细胞和自身免疫疾病相关的疾病。 所述方法包括对个体的细胞施用包含编码蛋白质的核苷酸序列的核酸分子的步骤，所述核苷酸序列包含与病原体抗原的表位相同或基本上相似的至少一个表位，相关的过度增殖细胞 蛋白质或与自身免疫疾病相关的蛋白质。 在每种情况下，核苷酸序列可操作地连接到调节序列以使得能够在细胞中表达。 核酸分子不含病毒颗粒，能够在所述细胞中表达。 细胞可以与细胞刺激剂接触细胞。 公开了预防和治疗个体免受HIV感染的方法。 公开了用于本发明的实践方法的药物组合物和试剂盒。
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公开(公告)号：USD1039353S1
公开(公告)日：2024-08-20
申请号：US29782500
申请日：2021-05-07
Abstract: FIG. 1 is a perspective view of a magnet showing our new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation view thereof;
FIG. 4 is a left side elevation view thereof;
FIG. 5 is a right side elevation view thereof;
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.
The broken line showing of a magnet is for the purpose of illustrating portions of the article and forms no part of the claimed design.-
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Patent Agency Ranking
公开(公告)号：US10369079B2
公开(公告)日：2019-08-06
申请号：US14579231
申请日：2014-12-22
Applicant: Andres Rodriguez , Pedrum Minaie , Tun Min Soe , Jason Shih , Andrew Dunn , Andrew Urazaki , Bin Wang , Fukang Jiang
Inventor： Andres Rodriguez , Pedrum Minaie , Tun Min Soe , Jason Shih , Andrew Dunn , Andrew Urazaki , Bin Wang , Fukang Jiang
Abstract: Embodiments of the present invention involve a refill apparatus comprising at least one pump, a plurality of reservoirs, a plurality of reservoir fluid channels each associated with one of the reservoirs, a plurality of valves, each having a cracking pressure, for fluidically sealing the reservoir fluid channels and the outlet fluid channel, an outlet fluid channel fluidically connected to the reservoir fluid channels, and a needle having a lumen in fluid communication with the outlet fluid channel. A parameter such as a pressure level is monitored, and one or more pumps and various ones of the valves are actuated in accordance with a protocol comprising a sequence of steps whereby fluidic pathways are opened between different ones of the reservoirs and the needle in a washing and filling sequence, each of the steps being associated with an expected pressure level.
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公开(公告)号：US09962437B2
公开(公告)日：2018-05-08
申请号：US14318330
申请日：2014-06-27
Applicant: Bin Wang , Huali Jin , Youmin Kang , Hsien-Jue Chu , Terry Kaleung Ng
Inventor： Bin Wang , Huali Jin , Youmin Kang , Hsien-Jue Chu , Terry Kaleung Ng
CPC classification number: A61K39/35 , A61K39/0003 , A61K39/0005 , A61K39/0008 , A61K2039/53 , A61K2039/57
Abstract: Compositions, methods, and kits for inhibiting an allergic response against an allergenic protein are disclosed. Compositions, methods and kits for inhibiting an allergic response against a flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a blomia tropicalis allergenic protein are disclosed.
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公开(公告)号：US09834516B2
公开(公告)日：2017-12-05
申请号：US12539800
申请日：2009-08-12
Applicant: Charles Michael Buchanan , Norma Lindsey Buchanan , Robert Thomas Hembre , Juanelle Little Lambert , Michael Eugene Donelson , Maryna Grigorievna Gorbunova , Thauming Kuo , Bin Wang
Inventor： Charles Michael Buchanan , Norma Lindsey Buchanan , Robert Thomas Hembre , Juanelle Little Lambert , Michael Eugene Donelson , Maryna Grigorievna Gorbunova , Thauming Kuo , Bin Wang
IPC: G02B1/04 , C08L1/14 , C07D233/54 , G02B1/14 , C08B1/00 , C08B3/06 , C08B3/16 , C08B3/28 , C08J5/18 , G02B5/30 , G02B1/10
CPC classification number: C07D233/54 , C08B1/003 , C08B3/06 , C08B3/16 , C08B3/28 , C08J5/18 , C08J2301/14 , G02B1/105 , G02B1/14 , G02B5/3083
Abstract: This invention relates to novel compositions comprising regioselectively substituted cellulose esters. One aspect of the invention relates to processes for preparing regioselectively substituted cellulose esters from cellulose dissolved in ionic liquids. Another aspect of the invention relates to the utility of regioselectively substituted cellulose esters in applications such as protective and compensation films for liquid crystalline displays.
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公开(公告)号：US20170112918A9
公开(公告)日：2017-04-27
申请号：US14318330
申请日：2014-06-27
Applicant: Bin Wang , Huali Jin , Youmin Kang , Hsien-Jue Chu , Terry Kaleung Ng
Inventor： Bin Wang , Huali Jin , Youmin Kang , Hsien-Jue Chu , Terry Kaleung Ng
IPC: A61K39/35
CPC classification number: A61K39/35 , A61K39/0003 , A61K39/0005 , A61K39/0008 , A61K2039/53 , A61K2039/57
Abstract: Compositions, methods, and kits for inhibiting an allergic response against an allergenic protein are disclosed. Compositions, methods and kits for inhibiting an allergic response against a flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a blomia tropicalis allergenic protein are disclosed.
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公开(公告)号：US20160374901A9
公开(公告)日：2016-12-29
申请号：US14579231
申请日：2014-12-22
Applicant: Andres Rodriguez , Pedrum Minaie , Tun Min Soe , Jason Shih , Andrew Dunn , Andrew Urazaki , Bin Wang , Fukang Jiang
Inventor： Andres Rodriguez , Pedrum Minaie , Tun Min Soe , Jason Shih , Andrew Dunn , Andrew Urazaki , Bin Wang , Fukang Jiang
CPC classification number: A61J1/22 , A61J1/201 , A61M5/14276 , A61M2005/14268 , B65B3/003
Abstract: Embodiments of the present invention involve a refill apparatus comprising at least one pump, a plurality of reservoirs, a plurality of reservoir fluid channels each associated with one of the reservoirs, a plurality of valves, each having a cracking pressure, for fluidically sealing the reservoir fluid channels and the outlet fluid channel, an outlet fluid channel fluidically connected to the reservoir fluid channels, and a needle having a lumen in fluid communication with the outlet fluid channel. A parameter such as a pressure level is monitored, and one or more pumps and various ones of the valves are actuated in accordance with a protocol comprising a sequence of steps whereby fluidic pathways are opened between different ones of the reservoirs and the needle in a washing and filling sequence, each of the steps being associated with an expected pressure level.
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