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    DRUG REFILL APPLICATOR SYSTEM AND METHOD OF USE
    3.
    发明申请
    DRUG REFILL APPLICATOR SYSTEM AND METHOD OF USE 审中-公开
    药物补充施用者系统及其使用方法

    公开(公告)号：US20150174007A1

    公开(公告)日：2015-06-25

    申请号：US14579231

    申请日：2014-12-22

    申请人： Andres Rodriguez ,  Pedrum Minaie ,  Tun Min Soe ,  Jason Shih ,  Andrew Dunn ,  Andrew Urazaki ,  Bin Wang ,  Fukang Jiang

    发明人： Andres Rodriguez ,  Pedrum Minaie ,  Tun Min Soe ,  Jason Shih ,  Andrew Dunn ,  Andrew Urazaki ,  Bin Wang ,  Fukang Jiang

    IPC分类号： A61J1/22 ,  A61M5/142 ,  B65B3/00

    CPC分类号： A61J1/22 ,  A61J1/201 ,  A61M5/14276 ,  A61M2005/14268 ,  B65B3/003

    摘要： Embodiments of the present invention involve a refill apparatus comprising at least one pump, a plurality of reservoirs, a plurality of reservoir fluid channels each associated with one of the reservoirs, a plurality of valves, each having a cracking pressure, for fluidically sealing the reservoir fluid channels and the outlet fluid channel, an outlet fluid channel fluidically connected to the reservoir fluid channels, and a needle having a lumen in fluid communication with the outlet fluid channel. A parameter such as a pressure level is monitored, and one or more pumps and various ones of the valves are actuated in accordance with a protocol comprising a sequence of steps whereby fluidic pathways are opened between different ones of the reservoirs and the needle in a washing and filling sequence, each of the steps being associated with an expected pressure level.

    摘要翻译： 本发明的实施例涉及一种再填充装置，其包括至少一个泵，多个储存器，多个储存器流体通道，每个储存器流体通道与储存器中的一个相关联，多个阀，每个具有开启压力，用于流体地密封储存器 流体通道和出口流体通道，流体连接到储存器流体通道的出口流体通道，以及具有与出口流体通道流体连通的内腔的针。 监测诸如压力水平的参数，并且根据包括一系列步骤的方案致动一个或多个泵和各种阀，其中在洗涤中不同储存器和针之间的流体路径打开 和填充顺序，每个步骤与预期压力水平相关联。

    Pressure sensing in implantable drug pumps
    7.
    发明授权
    Pressure sensing in implantable drug pumps 有权

    公开(公告)号：US10307530B2

    公开(公告)日：2019-06-04

    申请号：US14982246

    申请日：2015-12-29

    申请人： Jason Shih ,  Andrew Dunn

    发明人： Jason Shih ,  Andrew Dunn

    IPC分类号： A61M5/142 ,  A61M5/145 ,  G01L1/22

    摘要： In various embodiments, approaches to calibrating an implantable drug-delivery device feature a drug reservoir, an expandable electrolysis chamber, and an integrated strain gauge using a refill apparatus having one or more pumps, one or more refill reservoirs, an outlet fluid channel fluidically connected to the refill reservoir(s), and a needle having a lumen in fluid communication with the outlet fluid channel include inserting a needle into a refill port of the implantable drug-delivery device, monitoring a pressure change within the device, monitoring a pressure level of one or more components of the implantable drug-delivery device, and calibrating the monitored pressure level of the component(s) of the implantable drug-delivery device to the monitored pressure level of the outlet fluid channel.