公开(公告)号：US6103497A

公开(公告)日：2000-08-15

申请号：US205680

申请日：1998-12-04

申请人： Jennifer L. Hillman ,  Olga Bandman ,  Neil C. Corley ,  Preeti Lal ,  Purvi Shah

发明人： Jennifer L. Hillman ,  Olga Bandman ,  Neil C. Corley ,  Preeti Lal ,  Purvi Shah

IPC分类号： A61K38/00 ,  C07K14/47 ,  C12P21/00 ,  C07H21/04 ,  C07K14/46

CPC分类号： C07K14/4728 ,  A61K38/00

摘要： The invention provides two human S100 proteins designated individually as S100P1 and S10OP2 and collectively as S100P, and polynucleotides which identify and encode S100P. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of S100P.

摘要翻译： 本发明提供了分别命名为S100P1和S10OP2并统称为S100P的两种人S100蛋白，以及识别和编码S100P的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与S100P表达相关的疾病的方法。

公开(公告)号：US6096526A

公开(公告)日：2000-08-01

申请号：US82310

申请日：1998-05-20

申请人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Karl J. Guegler ,  Henry Yue

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Karl J. Guegler ,  Henry Yue

IPC分类号： C12N15/09 ,  A61K38/00 ,  A61P35/00 ,  C07K16/40 ,  C12N9/10 ,  C12N15/54 ,  C12Q1/68 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC分类号： C12N9/1007 ,  A61K38/00

摘要： The invention provides a human nucleic acid methylases (HNAM) and polynucleotides which identify and encode HNAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HNAM.

公开(公告)号：US6080847A

公开(公告)日：2000-06-27

申请号：US985335

申请日：1997-12-04

申请人： Jennifer L. Hillman ,  Henry Yue ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

发明人： Jennifer L. Hillman ,  Henry Yue ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

IPC分类号： C07K14/47 ,  C07H21/04 ,  C07H21/02

CPC分类号： C07K14/4702 ,  C07K14/4747

摘要： The invention provides three human proteins associated with cell proliferation, referred to collectively as "APOP" and individually as "APOP-1", "APOP-2", and "APOP-3", and polynucleotides which identify and encode APOP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of APOP.

公开(公告)号：US5981226A

公开(公告)日：1999-11-09

申请号：US193510

申请日：1998-11-17

申请人： Jennifer L. Hillman ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

IPC分类号： C07K14/47 ,  C12N1/21 ,  C12N15/12 ,  C12N15/63 ,  C12P21/00

CPC分类号： C07K14/47

摘要： The invention provides human vesicle transport associated proteins (VTAP) and polynucleotides which identify and encode VTAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of VTAP.

摘要翻译： 本发明提供了鉴定和编码VTAP的人囊泡转运相关蛋白（VTAP）和多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与VTAP表达相关的疾病的方法。

公开(公告)号：US5976801A

公开(公告)日：1999-11-02

申请号：US910927

申请日：1997-08-08

申请人： Olga Bandman ,  Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

发明人： Olga Bandman ,  Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

IPC分类号： A61K38/00 ,  C07K14/47 ,  C12N15/12 ,  C12Q1/68 ,  C12P19/34 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/4728 ,  A61K38/00

摘要： The invention provides two human reticulocalbin isoforms designated individually as RCN .gamma. and RCN .delta. and collectively as RCN, and polynucleotides which identify and encode RCN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RCN.

公开(公告)号：US5965395A

公开(公告)日：1999-10-12

申请号：US943600

申请日：1997-10-03

申请人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley

IPC分类号： C07K14/47 ,  C12P21/02 ,  C07H21/04 ,  C12N15/63

CPC分类号： C07K14/47

摘要： The invention provides a human maternally transcribed protein (HMTP) and polynucleotides which identify and encode HMTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HMTP.

公开(公告)号：US5962262A

公开(公告)日：1999-10-05

申请号：US900407

申请日：1997-07-25

申请人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

IPC分类号： C07K14/47 ,  C12N1/00 ,  C12N5/10 ,  C12N15/12 ,  C12N15/63 ,  C12P21/02

CPC分类号： C07K14/47

摘要： The invention provides a new human heat shock 27 like protein, (HSP27P) and polynucleotides which identify and encode HSP27P. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSP27P.

摘要翻译： 本发明提供了一种新的人类热休克27蛋白（HSP27P）和识别和编码HSP27P的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与HSP27P表达相关的疾病的方法。

公开(公告)号：US5932442A

公开(公告)日：1999-08-03

申请号：US933750

申请日：1997-09-23

申请人： Preeti Lal ,  Jennifer L. Hillman ,  Olga Bandman ,  Purvi Shah ,  Janice Au-Young ,  Henry Yue ,  Karl J. Guegler ,  Neil C. Corley

发明人： Preeti Lal ,  Jennifer L. Hillman ,  Olga Bandman ,  Purvi Shah ,  Janice Au-Young ,  Henry Yue ,  Karl J. Guegler ,  Neil C. Corley

IPC分类号： C12N15/09 ,  A61K38/00 ,  A61P35/00 ,  C07K14/47 ,  C07K16/18 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/00 ,  C12N15/12 ,  C12P21/02 ,  C12Q1/68 ,  G01N37/00 ,  C12P21/06 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC分类号： C12N9/93 ,  C07K14/4702 ,  A61K38/00 ,  Y10T436/143333

摘要： The invention provides human regulatory molecules and polynucleotides (collectively designated HRM) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, preventing, and treating disorders associated with expression of human regulatory molecules.

公开(公告)号：US5892012A

公开(公告)日：1999-04-06

申请号：US916901

申请日：1997-08-21

申请人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Purvi Shah

IPC分类号： C12N15/09 ,  A61K38/00 ,  A61K38/46 ,  A61K45/00 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07K16/18 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/16 ,  C12N15/55 ,  C12P21/02 ,  C12Q1/02 ,  C12Q1/68 ,  C07H21/02 ,  C07H21/00

CPC分类号： C12N9/16 ,  A61K38/00

摘要： The invention provides three human Rab proteins (RABP) and polynucleotides which identify and encode RABP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RABP.

摘要翻译： 本发明提供三种人类Rab蛋白（RABP）和识别和编码RABP的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与RABP表达相关的疾病的方法。

公开(公告)号：US5871973A

公开(公告)日：1999-02-16

申请号：US951148

申请日：1997-10-15

申请人： Jennifer L. Hillman ,  Olga Bandman ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

发明人： Jennifer L. Hillman ,  Olga Bandman ,  Preeti Lal ,  Purvi Shah ,  Neil C. Corley

IPC分类号： G01N33/53 ,  A61K38/00 ,  A61K39/395 ,  A61K45/00 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07K14/47 ,  C07K16/18 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12P21/02 ,  C12Q1/68 ,  G01N33/566 ,  C07K14/435

CPC分类号： C07K14/4738 ,  A61K38/00

摘要： The invention provides three human cell division regulators (HCDR) and polynucleotides which identify and encode HCDR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of HCDR.