公开(公告)号：US07009700B2

公开(公告)日：2006-03-07

申请号：US10742054

申请日：2003-12-18

申请人： Frank Dubois ,  Catherine Yourassowski

发明人： Frank Dubois ,  Catherine Yourassowski

IPC分类号： G01J3/30 ,  G03H1/26

CPC分类号： G01N21/6458 ,  G02B21/16 ,  G02B21/365 ,  G03H1/0005 ,  G03H1/041 ,  G03H1/0443 ,  G03H1/0465 ,  G03H1/0866 ,  G03H2001/005 ,  G03H2001/0452 ,  G03H2001/0456 ,  G03H2001/0458 ,  G03H2222/24 ,  G03H2223/14 ,  G03H2223/26

摘要： A method and device for obtaining a sample with three-dimensional microscopy, in particular a thick biological sample and the fluorescence field emitted by the sample. One embodiment includes obtaining interferometric signals of a specimen, obtaining fluorescence signals emanating from the specimen, recording these signals, and processing these signals so as to reconstruct three-dimensional images of the specimen and of the field of fluorescence emitted by the specimen at a given time. Another embodiment includes a digital holography microscope, a fluorescence excitation source illuminating a specimen, where the microscope and the fluorescence excitation source cooperate to obtain interferometric signals of the specimen and obtain fluorescence signals emanating from the specimen, means for recording the interferometric signals and fluorescence signals, and means for processing the interferometric signals and the fluorescence signals so as to reconstruct three-dimensional images of the specimen and of the field of fluorescence emitted by the specimen at a given time.

摘要翻译： 一种利用三维显微镜获得样品的方法和装置，特别是厚的生物样品和由样品发射的荧光场。 一个实施例包括获得样本的干涉信号，获得从样本发出的荧光信号，记录这些信号，以及处理这些信号，以便重建样本的三维图像和由给定的样本发射的荧光场 时间。 另一个实施例包括数字全息显微镜，照射样本的荧光激发源，其中显微镜和荧光激发源协作以获得样本的干涉信号并获得从样本发出的荧光信号，用于记录干涉信号和荧光信号的装置 以及用于处理干涉信号和荧光信号的装置，以便重建样本的三维图像和在给定时间由样本发射的荧光场。

公开(公告)号：US06943924B2

公开(公告)日：2005-09-13

申请号：US10497312

申请日：2002-12-04

申请人： Pierre Marquet ,  Etienne Cuche ,  Christian Depeursinge ,  Pierre Magistretti

发明人： Pierre Marquet ,  Etienne Cuche ,  Christian Depeursinge ,  Pierre Magistretti

IPC分类号： G03H1/06 ,  G03H1/08 ,  G03H1/22 ,  G06T1/00 ,  G03H1/02

CPC分类号： G03H1/0443 ,  G03H1/0005 ,  G03H1/0866 ,  G03H2001/0033 ,  G03H2001/0456 ,  G03H2001/0473 ,  G03H2210/30 ,  G03H2210/62 ,  G03H2210/63 ,  G03H2227/03 ,  G03H2240/54

摘要： The present invention is related to a method for performing digital holographic imaging (DHI), said DHI being characterized by the fact that images of a sample are obtained by applying numerical means to reconstruct holograms of the sample. In the method of the invention, the sample is in a medium with controlled properties that influence the behaviour of the sample, and/or that influence the process of hologram formation. The information content of one hologram, or of a plurality of holograms, recorded with the sample in one medium, or in a plurality of medium, is used to reconstruct one image of the sample, or a plurality of images of the sample, that describe quantitatively one property of the sample, or a plurality of properties of the sample. The present invention is also related to an apparatus with which to perform said method.

摘要翻译： 本发明涉及一种用于执行数字全息成像（DHI）的方法，所述DHI的特征在于，通过应用数值装置重建样品的全息图来获得样品的图像。 在本发明的方法中，样品处于影响样品行为的受控特性的介质和/或影响全息图形成过程的介质中。 使用在一个介质或多个介质中用样本记录的一个全息图或多个全息图的信息内容用于重建描述的样本或样本的多个图像的一个图像 定量的样品的一个性质，或样品的多个性质。 本发明还涉及一种用于执行所述方法的装置。

公开(公告)号：US20040212807A1

公开(公告)日：2004-10-28

申请号：US10607840

申请日：2003-06-27

发明人： Gregory R. Hanson ,  Philip R. Bingham

IPC分类号： G01B009/021

CPC分类号： G03H1/0406 ,  G03H1/0443 ,  G03H1/0866 ,  G03H1/265 ,  G03H1/28 ,  G03H2001/0456 ,  G03H2001/046 ,  G03H2001/0469 ,  G03H2226/11 ,  G03H2226/13

摘要： Systems and methods are described for faster processing of multiple spatially-heterodyned direct to digital holograms. A method includes of obtaining multiple spatially-heterodyned holograms, includes: digitally recording a first spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; digitally recording a second spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded first spatially-heterodyned hologram by shifting a first original origin of the recorded first spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a first angle between a first reference beam and a first, object beam; applying a first digital filter to cut off signals around the first original origin and performing an inverse Fourier transform on the result; Fourier analyzing the recorded second spatially-heterodyned hologram by shifting a second original origin of the recorded second spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a second angle between a second reference beam and a second object beam; and applying a second digital filter to cut off signals around the second original origin and performing an inverse Fourier transform on the result, wherein digitally recording the first spatially-heterodyned hologram is completed before digitally recording the second spatially-heterodyned hologram and a single digital image includes both the first spatially-heterodyned hologram and the second spatially-heterodyned hologram.

摘要翻译： 描述了用于更快处理多空间外差直接数字全息图的系统和方法。 一种包括获得多空间外差全息图的方法，包括：数字记录包括用于傅立叶分析的空间外差条纹的第一空间外差全息图; 数字记录包括用于傅立叶分析的空间外差条纹的第二空间外差全息图; 通过将所记录的第一空间外差全息图的第一原始原始位置（包括傅立叶空间中的空间外差条纹）移位到位于第一参考点之间的第一角度的空间外差载波频率之上，从而傅里叶分析所记录的第一空间外差全息图 光束和第一个物体光束; 施加第一数字滤波器以切断围绕第一原始原点的信号，并对该结果执行逆傅里叶变换; 通过将所记录的第二空间外差全息图的第二原始原点移动到傅立叶空间中的空间外差条纹，以置于空间外差载波频率的顶部上来对第二空间外差全息图进行傅立叶分析，该空间外差载波频率定义为第二参考 光束和第二物体光束; 以及施加第二数字滤波器以截断所述第二原始原点周围的信号并对所述结果执行逆傅里叶变换，其中在对所述第二空间外差全息图和单个数字图像进行数字记录之前完成数字记录所述第一空间外差全息图 包括第一空间外差全息图和第二空间外差全息图。

公开(公告)号：US20040042015A1

公开(公告)日：2004-03-04

申请号：US10234043

申请日：2002-09-03

发明人： Jeffery R. Price

IPC分类号： G01B009/02

CPC分类号： G03H1/0866 ,  G01B9/021 ,  G03H2001/0456

摘要： Systems and methods are described for content-based fused off-axis illumination direct-to-digital holography. A method includes calculating an illumination angle with respect to an optical axis defined by a focusing lens as a function of data representing a Fourier analyzed spatially heterodyne hologram; recording a content based spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; Fourier analyzing the recorded content based spatially heterodyne hologram including spatially heterodyne fringes by transforming axes of the recorded content based spatially heterodyne hologram including spatially heterodyne fringes in Fourier space to sit on top of a heterodyne carrier frequency defined as an angle between the reference beam and the object beam; applying a digital filter to cut off signals around an original origin; and then performing an inverse Fourier transform.

摘要翻译： 对基于内容的融合离轴照明直接数字全息术描述了系统和方法。 一种方法包括：计算相对于由聚焦透镜限定的光轴的照明角度作为表示傅立叶分析的空间外差全息图的数据的函数; 记录基于内容的空间外差全息图，包括用于傅立叶分析的空间外差条纹; 通过将所记录的内容的空间外差全息图的轴旋转，包括傅立叶空间中的空间外差条纹，以定位为参考光束与第二像素之间的角度的外差载波频率的顶部，傅里叶分析包含空间外差条纹的记录内容的空间外差全息图 物体光束 应用数字滤波器来切断围绕原始原点的信号; 然后执行逆傅里叶变换。

公开(公告)号：US20030016364A1

公开(公告)日：2003-01-23

申请号：US10166859

申请日：2002-06-11

发明人： Clarence E. Thomas ,  Gregory R. Hanson

IPC分类号： G01B009/021 ,  G03H001/02

CPC分类号： G03H1/0406 ,  G01B9/021 ,  G03H1/02 ,  G03H1/0443 ,  G03H1/0866 ,  G03H1/0891 ,  G03H1/22 ,  G03H1/2249 ,  G03H1/2294 ,  G03H2001/0033 ,  G03H2001/005 ,  G03H2001/0066 ,  G03H2001/0088 ,  G03H2001/0456 ,  G03H2001/2263 ,  G03H2210/30 ,  G03H2222/18 ,  G03H2226/11

摘要： Improvements to the acquisition and replay systems for direct-to-digital holography and holovision are described. A method of recording an off-axis hologram includes: splitting a laser beam into an object beam and a reference beam; reflecting the reference beam from a reference beam mirror; reflecting the object beam from an illumination beamsplitter; passing the object beam through an objective lens; reflecting the object beam from an object; focusing the reference beam and the object beam at a focal plane of a digital recorder to form an off-axis hologram; digitally recording the off-axis hologram; and transforming the off-axis hologram in accordance with a Fourier transform to obtain a set of results. A method of writing an off-axis hologram includes: passing a laser beam through a spatial light modulator; and focusing the laser beam at a focal plane of a photorefractive crystal to impose a holographic diffraction grating pattern on the photorefractive crystal. A method of replaying an off-axis hologram includes: illuminating a photorefractive crystal having a holographic diffraction grating with a replay beam.

公开(公告)号：US20010041296A1

公开(公告)日：2001-11-15

申请号：US09781881

申请日：2001-02-12

发明人： Daniel J.C. Herr ,  David Charles Joy

IPC分类号： G03H001/04 ,  H01L021/00

CPC分类号： G03H1/04 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/2002 ,  G03F7/2049 ,  G03F7/70408 ,  G03H1/02 ,  G03H1/0402 ,  G03H1/0866 ,  G03H5/00 ,  G03H2001/0038 ,  G03H2001/0094 ,  G03H2001/0204 ,  G03H2001/0456 ,  G03H2001/0469 ,  G03H2210/30 ,  G03H2222/34 ,  G03H2260/14 ,  G03H2260/62 ,  G03H2260/63 ,  H01J37/3174

摘要： A method for patterning a layer on a substrate can include projecting coherent radiation toward a reflector surface so that the coherent radiation is reflected off the reflector surface to provide a holographic projection of a desired image wherein the reflector surface includes information that corresponds to an inverse of the holographic projection of the desired image. The substrate including the layer can be maintained in the path of the reflected radiation so that the holographic projection is projected onto the layer. Related systems are also discussed.

摘要翻译： 用于图案化衬底上的层的方法可以包括将相干辐射投射到反射器表面，使得相干辐射从反射器表面反射以提供期望图像的全息投影，其中反射器表面包括对应于 所需图像的全息投影。 包括该层的衬底可以保持在反射辐射的路径中，使得全息投影投影到该层上。 还讨论了相关系统。

公开(公告)号：US20180188016A1

公开(公告)日：2018-07-05

申请号：US15590706

申请日：2017-05-09

申请人： National Taiwan Normal University

发明人： Chau-Jern Cheng ,  Chin-Yu Liu ,  Xin-Ji Lai

IPC分类号： G01B9/021 ,  G01B9/02 ,  G03H1/04 ,  G03H1/16

CPC分类号： G01B9/021 ,  G01B9/0201 ,  G01B9/02016 ,  G01B9/02018 ,  G01B9/0203 ,  G03H1/0443 ,  G03H2001/0033 ,  G03H2001/0447 ,  G03H2001/0456 ,  G03H2210/12 ,  G03H2223/12 ,  G03H2223/52 ,  G03H2223/55

摘要： A method for defect inspection of a transparent substrate comprises (a) providing an optical system for performing a diffraction process of object wave passing through a transparent substrate, (b) interfering and wavefront recording for the diffracted object wave and a reference wave to reconstruct the defect complex images (including amplitude and phase) of the transparent substrate, (c) characteristics analyzing, features classifying and sieving for the defect complex images of the transparent substrate, and (d) creating defect complex images database based-on the defect complex images for comparison and detection of the defect complex images of the transparent substrate.

公开(公告)号：US09733064B2

公开(公告)日：2017-08-15

申请号：US14442910

申请日：2013-11-15

申请人： Centre National de la Recherche Scientifique—CNRS

发明人： Michael Atlan ,  Benjamin Samson

IPC分类号： G01B9/02 ,  G01B9/021 ,  G03H1/00 ,  G03H1/08 ,  G01N21/45 ,  G03H1/04

CPC分类号： G01B9/021 ,  G01N21/453 ,  G03H1/0005 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/0033 ,  G03H2001/0456 ,  G03H2001/0463 ,  G03H2210/62 ,  G03H2227/03

摘要： The invention relates to a digital holography method for detecting the vibration amplitude of an object (15) having a vibration frequency ω, comprising: generating object illumination waves (Wt) and reference waves (WLO); acquiring interferograms between the reference wave (WLO) and a signal wave (Ws) by means of a bandwidth ω s detector (19), the reference wave comprising two components ELO1, ELO1 of frequencies ω1, ω2 that are respectively staggered in relation to the laser frequency ωL by a quantity δ1=γ1ωs and δ2=qω+γ2ωs, where q is an integer and −0.5≦γ1, γ2≦0.5; and calculating the vibration amplitude of the object from the optical beats spectrum deduced from the complex amplitude of an interferogram.

公开(公告)号：US09599960B2

公开(公告)日：2017-03-21

申请号：US14567436

申请日：2014-12-11

申请人： CANON KABUSHIKI KAISHA

发明人： Akira Eguchi

IPC分类号： G01B9/021 ,  G03H1/04

CPC分类号： G03H1/0443 ,  G03H2001/0456 ,  G03H2001/046 ,  G03H2001/0471 ,  G03H2210/62 ,  G03H2222/42 ,  G03H2222/44 ,  G03H2223/14

摘要： The imaging apparatus includes an optical system dividing light into object and reference beams and causing the object beam and the reference beam to interfere with each other to form interference fringes on an image sensor. A processor performs multiple imaging processes for the interference fringes with different incident angles of the object beam to an object, a first process to acquire a transmitted wavefront for each incident angle and a second process to calculate a three-dimensional refractive index distribution from the transmitted wavefronts. The apparatus includes a modulator changing a phase distribution of light in any one of an optical path from a light source to a dividing element, a reference beam path and an optical path from a combining element to the image sensor and causes the modulator to change the phase distribution in at least one of the multiple imaging processes.

公开(公告)号：US09581961B2

公开(公告)日：2017-02-28

申请号：US14433528

申请日：2013-10-04

申请人： University of Hyogo

发明人： Kunihiro Sato

IPC分类号： G03H1/04 ,  G03H1/00 ,  G02B21/06 ,  G02B21/36 ,  G03H1/08 ,  G03H1/26

CPC分类号： G03H1/0005 ,  G02B21/06 ,  G02B21/365 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/005 ,  G03H2001/0445 ,  G03H2001/0447 ,  G03H2001/0456 ,  G03H2001/0825 ,  G03H2001/0883 ,  G03H2001/266 ,  G03H2222/13 ,  G03H2222/42 ,  G03H2222/52 ,  G03H2226/02

摘要： The present method includes a data acquisition process and tomographic image generation processes. In the data acquisition process, holograms of an object light and so forth are acquired for each light with a wavelength by changing the wavelengths of the illumination light, off-axis spherical wave reference light, and inline spherical wave reference light. In the tomographic image generation process, a reconstructed light wave of the object light and a reconstructed light wave of the illumination light on a reconstruction surface are generated from these holograms. A reconstruction light wave with adjusted phase is added up for each wavelength to generate a tomographic hologram. From this, an accurate and focused tomographic image without distortion can be generated.

摘要翻译： 本方法包括数据采集处理和断层图像生成处理。 在数据采集处理中，通过改变照明光的波长，离轴球面波参考光和直列球面波参考光，获得具有波长的每个光的物体光等的全息图。 在断层图像生成处理中，从这些全息图生成物体光的重建光波和重构面上的照明光的重建光波。 对于每个波长加上调整相位的重建光波，以产生断层全息图。 由此，可以产生无失真的准确且聚焦的断层图像。