GENOME-SCALE ANALYSIS OF ABERRANT DNA METHYLATION IN COLORECTAL CANCER
    82.
    发明申请
    GENOME-SCALE ANALYSIS OF ABERRANT DNA METHYLATION IN COLORECTAL CANCER 审中-公开
    染色体癌细胞DNA甲基化的基因分析

    公开(公告)号:US20130065228A1

    公开(公告)日:2013-03-14

    申请号:US13486988

    申请日:2012-06-01

    CPC classification number: C12Q1/6886 C12Q2600/154 C12Q2600/158

    Abstract: Particular aspects provide methods and compositions (e.g., gene marker panels) having substantial utility for at least one of diagnosis, identification and classification of colorectal cancer (CRC) (e.g., tumors) relating to distinctive DNA methylation-based subgroups of CRC including CpG island methylator phenotype (CIMP) groups (e.g., CIMP-H and CIMP-L) and non-CIMP groups. Exemplary marker panels include: B3GAT2, FOXL2, KCNK13, RAB31 and SLIT1 (CIMP marker panel); and FAM78A, FSTL1, KCNC1, MYOCD, and SLC6A4 (CIMP-H marker panel). Further aspects relate to genetic mutations, and other epigenetic markers relating to said CRC subgroups that can be used in combination with the gene marker panels for at least one of diagnosis, identification and classification of colorectal cancer (CRC) (e.g., tumors) relating to distinctive CIMP and non-CIMP groups.

    Abstract translation: 具体方面提供了方法和组合物(例如,基因标记物组),其具有与基于特异性DNA甲基化的CRC亚基(包括CpG岛)相关的结肠直肠癌(CRC)(例如肿瘤)的诊断,鉴定和分类中的至少一种的实质效用 甲基化表型(CIMP)组(如CIMP-H和CIMP-L)和非CIMP组。 示例性标记面板包括:B3GAT2,FOXL2,KCNK13,RAB31和SLIT1(CIMP标记物组); 和FAM78A,FSTL1,KCNC1,MYOCD和SLC6A4(CIMP-H标记物组)。 其它方面涉及遗传突变和与所述CRC亚组相关的其它表观遗传标记,其可以与基因标记物组合使用,用于诊断,鉴定和分类结肠直肠癌(CRC)(例如肿瘤)中的至少一种 独特的CIMP和非CIMP组。

    MEMS diaphragm
    83.
    发明授权
    MEMS diaphragm 有权
    MEMS隔膜

    公开(公告)号:US08390085B2

    公开(公告)日:2013-03-05

    申请号:US13072358

    申请日:2011-03-25

    CPC classification number: B81C1/00587 B81B2201/0257 B81B2203/0127

    Abstract: A microelectromechanical system (MEMS) diaphragm is provided. The MEMS diaphragm includes a first conductive layer, a second conductive layer and a first dielectric layer. The first conductive layer is disposed on a substrate and having a plurality of openings. The openings having a first dimension and the openings having a second dimension are arranged alternately, and the first dimension is not equal to the second dimension. The second conductive layer is disposed between the first conductive layer and the substrate. The first dielectric layer is partially disposed between the first conductive layer and the second conductive layer, so that a portion of the first conductive layer is suspended.

    Abstract translation: 提供了微机电系统(MEMS)隔膜。 MEMS隔膜包括第一导电层,第二导电层和第一介电层。 第一导电层设置在基板上并且具有多个开口。 具有第一尺寸的开口和具有第二尺寸的开口交替布置,并且第一尺寸不等于第二尺寸。 第二导电层设置在第一导电层和衬底之间。 第一介电层部分地设置在第一导电层和第二导电层之间,使得第一导电层的一部分被悬挂。

    Orthogonal frequency division multiple access with carrier sense
    85.
    发明授权
    Orthogonal frequency division multiple access with carrier sense 有权
    具有载波侦听的正交频分多址

    公开(公告)号:US08374130B2

    公开(公告)日:2013-02-12

    申请号:US12020212

    申请日:2008-01-25

    Abstract: A communication system in which an access point and one or more devices communicating through the access point adaptively apply Orthogonal Frequency Division Multiple Access (OFDMA). The access point may assign orthogonal subcarriers to devices as in conventional OFDMA, but the access point senses activity on the subcarriers and selects subcarriers without activity for assignment. In an alternative approach, a device that is configured for OFDMA communication may receive a channel assignment from a device that does not support OFDMA. The OFDMA-capable device may use only a portion of the subcarriers in the assigned channel, which may be communicated to the non-OFDMA device. During the non-OFDMA device may then ignore unused subcarriers in error detection and correction to avoid incorrectly classifying communications as erroneous. Information about OFDMA capabilities, subcarrier assignments and subcarriers in use may be communicated as information elements in network control communications, such as beacons and probe messages.

    Abstract translation: 一种通信系统,其中接入点和通过接入点通信的一个或多个设备自适应地应用正交频分多址(OFDMA)。 接入点可以像传统OFDMA那样将正交子载波分配给设备,但是接入点感测对子载波的活动,并且选择没有用于分配的活动的子载波。 在替代方法中,配置用于OFDMA通信的设备可以从不支持OFDMA的设备接收信道分配。 具有OFDMA能力的设备可以仅使用所分配的信道中的子载波的一部分,其可以被传送到非OFDMA设备。 在非OFDMA设备期间,可以忽略错误检测和校正中的未使用的子载波,以避免将通信错误地分类为错误的。 关于OFDMA能力,子载波分配和正在使用的子载波的信息可以作为诸如信标和探测消息的网络控制通信中的信息元素传送。

    COMPOSITIONS AND METHODS FOR IMPROVED PLANT FEEDSTOCK
    86.
    发明申请
    COMPOSITIONS AND METHODS FOR IMPROVED PLANT FEEDSTOCK 有权
    改进植物饲料的组合物和方法

    公开(公告)号:US20120322122A1

    公开(公告)日:2012-12-20

    申请号:US13462583

    申请日:2012-05-02

    Abstract: The invention provides methods for modifying lignin content and composition in plants and achieving associated benefits therefrom involving altered expression of newly discovered MYB4 transcription factors. Nucleic acid constructs for modifying MYB4 transcription factor expression are described. By over-expressing the identified MYB4 transcription factors, for example, an accompanying decrease in lignin content may be achieved. Plants are provided by the invention comprising such modifications, as are methods for their preparation and use.

    Abstract translation: 本发明提供了修饰植物中木质素含量和组成的方法,并且实现了相关益处,从而涉及新发现的MYB4转录因子的改变表达。 描述了用于修饰MYB4转录因子表达的核酸构建体。 例如,通过过度表达鉴定的MYB4转录因子,可以实现伴随的木质素含量的降低。 植物由包括这些修饰的本发明提供,以及它们的制备和使用方法。

    METHOD FOR FEEDING BACK CHANNEL STATE INFORMATION, AND METHOD AND DEVICE FOR OBTAINING CHANNEL STATE INFORMATION
    87.
    发明申请
    METHOD FOR FEEDING BACK CHANNEL STATE INFORMATION, AND METHOD AND DEVICE FOR OBTAINING CHANNEL STATE INFORMATION 有权
    用于提供反向信道状态信息的方法,以及用于获取信道状态信息的方法和设备

    公开(公告)号:US20120257579A1

    公开(公告)日:2012-10-11

    申请号:US13529383

    申请日:2012-06-21

    Abstract: Embodiments of the present invention provide a method for feeding back channel state information, and a method and a device for obtaining channel state information. The method for feeding back the channel state information includes: compressing, by a user equipment, original time domain channel state information to obtain compressed time domain Channel state information: quantizing the compressed time domain channel state information to obtain a codebook index; and sending the codebook index to a base station. With the technical solutions provided by the embodiments of the present invention, the total overhead used for feeding back the channel state information from the user equipment to the base station is reduced.

    Abstract translation: 本发明的实施例提供一种用于反馈信道状态信息的方法,以及用于获得信道状态信息的方法和装置。 用于反馈信道状态信息的方法包括:由用户设备压缩原始时域信道状态信息以获得压缩时域信道状态信息:量化压缩的时域信道状态信息以获得码本索引; 并将码本索引发送到基站。 利用本发明实施例提供的技术方案,减少了从用户设备向基站反馈信道状态信息的总开销。

    PRIORITY HASH INDEX
    88.
    发明申请
    PRIORITY HASH INDEX 有权
    优先哈希指数

    公开(公告)号:US20120173510A1

    公开(公告)日:2012-07-05

    申请号:US12980582

    申请日:2010-12-29

    CPC classification number: G06F17/30628

    Abstract: A priority hash index provides efficient lookup of posting lists for search query terms. The priority hash index is a data structure in which hash values for terms are distributed across multiple storage devices based on importance of the terms and access speeds of the storage devices. Terms are grouped into search lists with each search list including a storage location on each storage device. When a search query is received, a term is identified and hashed to a location on the first storage device and to generate a unique hash value for the term. The locations on the storage device for the term's search list are sequentially read until the hash value for the term is located to access the posting list for the term.

    Abstract translation: 优先哈希索引提供了有效查找搜索查询条款的发布列表。 优先散列索引是一种数据结构,其中术语的哈希值基于存储设备的术语和访问速度的重要性在多个存储设备上分布。 术语被分组到搜索列表中,每个搜索列表包括每个存储设备上的存储位置。 当接收到搜索查询时,将对术语进行识别并将其散列到第一存储设备上的位置,并为该术语生成唯一的哈希值。 顺序读取术语搜索列表的存储设备上的位置,直到该术语的哈希值位于访问该术语的发布列表。

    LIGHT EMITTING DIODE AND METHOD FOR MANUFACTURING THE SAME
    90.
    发明申请
    LIGHT EMITTING DIODE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
    发光二极管及其制造方法

    公开(公告)号:US20120104407A1

    公开(公告)日:2012-05-03

    申请号:US13172734

    申请日:2011-06-29

    CPC classification number: H01L33/20 H01L33/22 H01L33/32

    Abstract: An LED includes a substrate, a first n-type GaN layer, a connecting layer, a second n-type GaN layer, a light emitting layer, and a p-type GaN layer. The first n-type GaN layer is formed on the substrate, the first n-type GaN layer has a first surface facing away from the substrate, and the first surface includes a first area and a second area. The connecting layer, the second n-type GaN layer, the light emitting layer, and the p-type GaN layer are formed on the first area in sequence. The connecting layer is etchable by alkaline solution; a bottom surface of the second n-type GaN layer facing towards the connecting layer has a roughened exposed portion; the GaN on the bottom surface of the second n-type GaN layer is N-face GaN.

    Abstract translation: LED包括基板,第一n型GaN层,连接层,第二n型GaN层,发光层和p型GaN层。 第一n型GaN层形成在基板上,第一n型GaN层具有背离基板的第一表面,第一表面包括第一区域和第二区域。 连续层,第二n型GaN层,发光层和p型GaN层依次形成在第一区域上。 连接层可用碱性溶液蚀刻; 面向连接层的第二n型GaN层的底表面具有粗糙化的暴露部分; 第二n型GaN层的底面上的GaN为N面GaN。

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