公开(公告)号：US20060052385A1

公开(公告)日：2006-03-09

申请号：US10515165

申请日：2003-05-25

Applicant: Wesley Blackaby ,  Jose Castro Pineiro ,  Simon Goodacre ,  David Hallett ,  Alexander Humphries ,  Philip Jones ,  Kevin Merchant ,  Michael Reader

Inventor： Wesley Blackaby ,  Jose Castro Pineiro ,  Simon Goodacre ,  David Hallett ,  Alexander Humphries ,  Philip Jones ,  Kevin Merchant ,  Michael Reader

IPC: A61K31/506 ,  A61K31/502 ,  A61K31/497 ,  C07D471/02

CPC classification number: C07D471/04

Abstract: A class of 8-fluoroimidazo[1,2-α]pyridine derivatives, substituted at the 3-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.

Abstract translation: 一类由任选取代的五元或六元杂芳环在3-位被取代的8-氟咪唑并[1,2-α]吡啶衍生物，是GABA A A受体的选择性配体 特别是对α2和/或α3和/或α5亚基具有高亲和力，因此有益于治疗和/或预防中枢神经系统的不利条件，包括焦虑，抽搐和认知障碍。

公开(公告)号：US20050166983A1

公开(公告)日：2005-08-04

申请号：US10772043

申请日：2004-02-03

Applicant: James Shaw ,  Philip Jones

Inventor： James Shaw ,  Philip Jones

IPC: B64D37/00 ,  G05D7/00

CPC classification number: B64C1/1453 ,  B64D11/02 ,  Y02T50/46 ,  Y10T137/6906

Abstract: The waste disposal service panel assembly includes a housing, waste drain valve, rinse/fill valve, handle assembly and service panel door. The housing has a tubular side wall and a base near one end of the side wall. The waste drain valve is at least partially mounted within the housing through the base. The waste drain valve includes an outlet positioned within the housing and an inlet configured to couple to a waste collection tank within a aircraft. The service panel door is pivotally coupled to the housing near an end of the side wall remote from the base. The service panel door has an outer surface configured to substantially match an outer contour of the aircraft's skin, and an outer cap coupled to an inner surface of the service panel door. The outer cap is configured and dimensioned to mate with the outlet to seal the outlet when the service panel door is closed.

Abstract translation: 废物处理维修面板组件包括壳体，排泄阀，冲洗/填充阀，手柄组件和维修面板门。 壳体具有管状侧壁和靠近侧壁一端的底座。 废物排放阀至少部分地通过底座安装在壳体内。 废物排放阀包括位于壳体内的出口和配置成耦合到飞行器内的废物收集箱的入口。 维修面板门可靠近靠近底座的侧壁的端部连接到壳体。 维修面板门具有被配置为基本上匹配飞行器的皮肤的外轮廓的外表面和联接到维修面板门的内表面的外盖。 外盖的构造和尺寸设计为与出口配合，以在维修面板门关闭时密封出口。

公开(公告)号：US6141546A

公开(公告)日：2000-10-31

申请号：US953126

申请日：1997-10-17

Applicant: Howard John Thomas ,  Rupinder Singh Oberoi ,  Christopher Parker ,  Philip Jones

Inventor： Howard John Thomas ,  Rupinder Singh Oberoi ,  Christopher Parker ,  Philip Jones

IPC: H04B17/00 ,  H04W24/00 ,  H04W24/08 ,  H04B1/00

CPC classification number: H04W24/08 ,  H04B17/391 ,  H04W24/00 ,  H04W24/06 ,  H04W24/10 ,  H04W28/16 ,  H04W72/02 ,  H04W88/08

Abstract: In a mobile cellular communication system, adjacent basestations BS1-BS4 are assigned different selections of different frequency channels to communicate with mobiles in their cells (10, etc.). To improve system quality and capacity, a basestation selects a frequency channel which is not assigned to it or any neighbour station, and makes test communications on that frequency channel with mobiles (e.g. MS1) in its cell. The basestation assesses the potential performance of that frequency channel, and neighbour basestations can monitor for potential interference on that frequency channel. The information so gathered can be analysed by an operations maintenance station OMC.

Abstract translation: 在移动蜂窝通信系统中，相邻基站BS1-BS4被分配不同频率信道的不同选择，以与其小区（10等）中的移动台通信。 为了提高系统质量和容量，基站选择一个没有分配给它或任何相邻站的频道，并在其小区中用移动台（例如MS1）在该频道上进行测试通信。 基站评估该频道的潜在性能，邻居基站可以监视该频道上的潜在干扰。 所收集的信息可以由操作维护站OMC进行分析。

公开(公告)号：US4113826A

公开(公告)日：1978-09-12

申请号：US761900

申请日：1977-01-24

Applicant: Alan Philip Jones

Inventor： Alan Philip Jones

IPC: F16K1/00 ,  B29C35/00 ,  B29C43/00 ,  B29C45/00 ,  B29C45/14 ,  B29C55/00 ,  B29C65/70 ,  F16K27/02 ,  B29F1/00

CPC classification number: F16K27/0272 ,  B29C45/14622

Abstract: A method of forming an injection moulded lining on a valve body comprises the step of defining a cavity having a main portion which when filled with lining material forms the desired lining, and an extension portion continuous with an edge of the main portion. Lining material is injected into the extension portion until the cavity is filled. Any sprues produced by the injection are on the tab formed by the material in the extension portion and not on the lining proper. Thus, there is no danger of damaging the lining as sprues are removed, and they do not cause local stress in the lining.

Abstract translation: 在阀体上形成注射成型衬垫的方法包括以下步骤：确定具有主要部分的空腔，当填充衬里材料形成期望的衬里时，以及与主要部分的边缘连续的延伸部分。 衬里材料被注入到延伸部分中，直到空腔被填充。 由注射产生的任何浇道都在由延伸部分中的材料形成的接片上，而不是在衬里上。 因此，除去浇口不会损坏衬里，并且不会在衬里中引起局部应力。

公开(公告)号：US1220835A

公开(公告)日：1917-03-27

申请号：US12175816

申请日：1916-09-23

Applicant: FORBES PHILIP JONES

Inventor： FORBES PHILIP JONES

CPC classification number: B65D9/22

公开(公告)号：US20130158003A1

公开(公告)日：2013-06-20

申请号：US13700051

申请日：2011-05-26

Applicant: John Emmerson Campbell ,  Michael Charles Hewitt ,  Philip Jones ,  Linghong Xie

Inventor： John Emmerson Campbell ,  Michael Charles Hewitt ,  Philip Jones ,  Linghong Xie

IPC: C07D403/06 ,  C07D409/06 ,  C07D405/14 ,  C07D409/14 ,  C07D498/04 ,  C07D417/06 ,  C07D413/06 ,  C07D487/04 ,  C07D471/14 ,  C07D471/04 ,  C07D401/14

CPC classification number: C07D498/06 ,  A61K31/4164 ,  A61K31/4178 ,  A61K31/4709 ,  A61K31/498 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/517 ,  A61K31/5383 ,  C07D233/58 ,  C07D401/06 ,  C07D401/14 ,  C07D403/06 ,  C07D405/14 ,  C07D409/06 ,  C07D409/14 ,  C07D413/06 ,  C07D417/06 ,  C07D471/04 ,  C07D471/06 ,  C07D471/14 ,  C07D487/04 ,  C07D491/056 ,  C07D498/04 ,  C07D498/14 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

公开(公告)号：US20130048783A1

公开(公告)日：2013-02-28

申请号：US13569528

申请日：2012-08-08

Applicant: Andrija Ekmedzic ,  Mario Straccia ,  Philip Jones

Inventor： Andrija Ekmedzic ,  Mario Straccia ,  Philip Jones

IPC: B64C25/10

CPC classification number: B64C25/04

Abstract: A landing gear attachment apparatus (100) hasa landing gear side bearing retention arrangement (104) connected to an aircraft side attachment apparatus (102), held together by a series of fuse pins. The interaction between a fuse pin carrier and a trunnion block varies the amount of load required to separate the landing gear from the fuselage depending on the direction of the load.

Abstract translation: 起落架附接装置（100）具有连接到飞行器侧连接装置（102）的起落架侧轴承保持装置（104），其通过一系列熔丝销保持在一起。 保险丝销托架和耳轴座之间的相互作用根据负载方向改变将起落架与机身分离所需的负载量。

公开(公告)号：US08188084B2

公开(公告)日：2012-05-29

申请号：US12227513

申请日：2007-05-25

Applicant: Philip Jones ,  Olaf Kinzel ,  Giovanna Pescatore ,  Laura Llauger Bufi ,  Carsten Schultz-Fademrecht ,  Federica Ferrigno

Inventor： Philip Jones ,  Olaf Kinzel ,  Giovanna Pescatore ,  Laura Llauger Bufi ,  Carsten Schultz-Fademrecht ,  Federica Ferrigno

IPC: C07D401/12 ,  A61P35/00 ,  A61P9/10 ,  A61P29/00

CPC classification number: C07D471/04 ,  A61K31/435 ,  A61K31/495 ,  C07D237/14 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/10 ,  C07D403/12 ,  C07D403/14 ,  C07D405/10 ,  C07D471/10 ,  C07D487/04 ,  C07D491/10

Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.

Abstract translation: 本发明涉及式I化合物及其药学上可接受的盐或互变异构体，其是聚（ADP-核糖）聚合酶（PARP）的抑制剂，因此可用于治疗癌症，炎性疾病，再灌注损伤，缺血性病症，中风 ，肾衰竭，心血管疾病，心血管疾病以外的血管疾病，糖尿病，神经变性疾病，逆转录病毒感染，视网膜损伤，皮肤衰老和紫外线诱发的皮肤损伤，以及用于癌症治疗的化学或放射增敏剂。

公开(公告)号：US08126451B2

公开(公告)日：2012-02-28

申请号：US12016663

申请日：2008-01-18

Applicant: Carlo Luschi ,  Steve Allpress ,  Philip Jones

Inventor： Carlo Luschi ,  Steve Allpress ,  Philip Jones

IPC: H04W4/00

CPC classification number: H04B17/345 ,  H04B1/7115 ,  H04B17/27 ,  H04B17/318 ,  H04B17/336 ,  H04L25/0212 ,  H04L25/0224 ,  H04L25/03019

Abstract: Methods are described of processing signals received over a wireless communication channel by a receiver in a wireless cellular network. A method includes receiving a sequence of signal samples. The received sequence of samples can be used to estimate at least one channel coefficient for at least one transmission path. An estimate of an orthogonality factor can be generated based on said at least one channel coefficient. An estimate of the disturbance can be generated based on said at least one estimated channel coefficient. An estimate of input signal power can be generated using the received sequence. An estimate of cell geometry can be generated using the estimated orthogonality factor, estimated disturbance, and estimated input signal power. The estimate of cell geometry can be used in processing received data samples. Related methods of processing digital samples are described. Related receivers are also described.

Abstract translation: 描述了处理由无线蜂窝网络中的接收机在无线通信信道上接收的信号的方法。 一种方法包括接收信号样本序列。 所接收的样本序列可以用于估计至少一个传输路径的至少一个信道系数。 可以基于所述至少一个信道系数来生成正交因子的估计。 可以基于所述至少一个估计的信道系数来产生扰动的估计。 可以使用接收到的序列来生成输入信号功率的估计。 可以使用估计的正交因子，估计的干扰和估计的输入信号功率来生成小区几何的估计。 单元几何的估计可用于处理接收的数据样本。 描述处理数字样本的相关方法。 还描述了相关接收机。

公开(公告)号：US08080573B2

公开(公告)日：2011-12-20

申请号：US12084269

申请日：2006-10-26

Applicant: Philip Jones ,  Jesus Maria Ontoria Ontoria

Inventor： Philip Jones ,  Jesus Maria Ontoria Ontoria

IPC: A61K31/4164 ,  C07D233/54

CPC classification number: C07D403/12 ,  C07D233/64 ,  C07D409/14

Abstract: The present invention related to compounds of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Compounds of the present invention are useful for treating or preventing neurodegenerative diseases, schizophrenia and stroke among other diseases.

Abstract translation: 本发明涉及式（I）化合物：或其药学上可接受的盐，立体异构体或互变异构体。 本发明化合物是组蛋白脱乙酰酶（HDAC）的抑制剂，可用于治疗包括癌症在内的细胞增殖性疾病。 本发明的化合物可用于治疗或预防神经变性疾病，精神分裂症和中风等疾病。