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    IMPLANTABLE OPTICAL HEMODYNAMIC SENSOR INCLUDING AN EXTENSION MEMBER
    83.
    发明申请
    IMPLANTABLE OPTICAL HEMODYNAMIC SENSOR INCLUDING AN EXTENSION MEMBER 审中-公开
    可伸缩的光学血液动力学传感器，包括延伸部件

    公开(公告)号：US20100022861A1

    公开(公告)日：2010-01-28

    申请号：US12180991

    申请日：2008-07-28

    申请人： Can Cinbis ,  Richard James O'Brien ,  James Kevin Carney

    发明人： Can Cinbis ,  Richard James O'Brien ,  James Kevin Carney

    IPC分类号： A61B5/1459 ,  A61B5/026 ,  A61B5/00

    CPC分类号： A61N1/3704 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/02154 ,  A61B5/0261 ,  A61B5/14542 ,  A61B5/1459 ,  A61N1/36557 ,  A61N1/36571 ,  A61N1/375 ,  A61N1/3962

    摘要： An implantable medical device includes an optical hemodynamic sensor comprising at least one optical emitter and at least one detector. In some examples, the at least one optical emitter may be optically coupled to at least one light transmission member that extends from a housing of the medical device. In addition, in some examples, the at least one detector may be optically coupled to at least one light transmission member that extends from the housing of the medical device. In other examples, an optical emitter and/or detector of a hemodynamic sensor may be carried by an elongated member that extends from a housing of the IMD. The elongated member may electrically couple the optical emitter and/or detector to a controller or other components within the IMD housing.

    摘要翻译： 可植入医疗装置包括光学血液动力学传感器，其包括至少一个光发射器和至少一个检测器。 在一些示例中，至少一个光发射器可以光耦合到从医疗装置的壳体延伸的至少一个光透射构件。 此外，在一些示例中，至少一个检测器可以光耦合到从医疗装置的壳体延伸的至少一个光传输构件。 在其他示例中，血液动力学传感器的光学发射器和/或检测器可以由从IMD的壳体延伸的细长构件承载。 细长构件可以将光学发射器和/或检测器电耦合到IMD壳体内的控制器或其它部件。

    Method and apparatus for using an optical hemodynamic sensor to identify an unstable arrhythmia
    84.
    发明申请
    Method and apparatus for using an optical hemodynamic sensor to identify an unstable arrhythmia 有权
    使用光学血液动力学传感器来识别不稳定心律失常的方法和装置

    公开(公告)号：US20070239215A1

    公开(公告)日：2007-10-11

    申请号：US11394477

    申请日：2006-03-31

    申请人： Sourav Bhunia ,  Walter Olson ,  Can Cinbis

    发明人： Sourav Bhunia ,  Walter Olson ,  Can Cinbis

    IPC分类号： A61N1/00

    CPC分类号： A61B5/14542 ,  A61B5/1459 ,  A61N1/3621 ,  A61N1/36557 ,  A61N1/3956

    摘要： A medical device identifies a hemodynamically unstable arrhythmia based upon optical hemodynamic sensor signals. The optical hemodynamic sensor includes a light source for transmitting light corresponding to first and second wavelengths through a blood perfused tissue of a patient and a light detector for generating optical signals corresponding to an intensity of the detected light at the first and second wavelengths. At a low motion period for the patient, optical signals are obtained from the optical hemodynamic sensor and are analyzed to determine a baseline motion level for the patient. Subsequent signals obtained from the optical hemodynamic sensor are compared to the baseline motion levels, with only those signals corresponding to periods where motion does not exceed the baseline level of motion being further analyzed to determine if they are consistent with a hemodynamically unstable arrhythmia.

    摘要翻译： 医疗设备基于光学血液动力学传感器信号识别血液动力学不稳定的心律失常。 光学血液动力学传感器包括用于通过患者的血液灌注组织透射与第一和第二波长相对应的光的光源，以及用于产生与第一和第二波长的检测光的强度对应的光信号的光检测器。 在患者的低运动周期中，从光学血液动力学传感器获得光学信号，并且被分析以确定患者的基线运动水平。 将从光学血液动力学传感器获得的后续信号与基线运动水平进行比较，只有那些对应于运动未超过基线运动水平的周期的信号进行进一步分析，以确定它们是否与血液动力学不稳定的心律失常一致。

    Method and apparatus for post-shock evaluation using tissue oxygenation measurements
    86.
    发明授权
    Method and apparatus for post-shock evaluation using tissue oxygenation measurements 有权
    使用组织氧合测量进行休克后评估的方法和装置

    公开(公告)号：US08918171B2

    公开(公告)日：2014-12-23

    申请号：US12845843

    申请日：2010-07-29

    申请人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    发明人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    IPC分类号： A61N1/365 ,  A61N1/39 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/1459

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a monitoring module detecting a cardiac event in response to the sensed cardiac signals using first detection criteria, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the monitoring module, the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, determine a recovery index in response to the determined tissue oxygenation trend, and control one or both of detecting a cardiac event by the monitoring module and delivery of therapy by the therapy delivery module in response to the determined recovery index.

    摘要翻译： 一种用于递送疗法的方法和装置，其包括用于感测心脏信号并递送治疗的电极，监测模块，响应于使用第一检测标准的所感测到的心脏信号检测心脏事件，发射光并检测由 与所述传感器相邻的组织体积以产生相应的检测到的光强度输出信号;控制模块，耦合到所述传感器以响应于递送所述治疗来控制所述传感器的光发射;以及控制器，耦合到所述监测模块，所述治疗递送模块 以及所述传感器，所述控制器被配置为响应于所述输出信号确定组织氧合测量，响应于组织氧合测量确定组织氧合趋势，响应于所确定的组织氧合趋势确定恢复指数，并且控制一个或两个 通过监测模块检测心脏事件并进行治疗 y由治疗递送模块响应于确定的恢复指数。

    Method and apparatus for post-shock evaluation using tissue oxygenation measurements
    87.
    发明授权
    Method and apparatus for post-shock evaluation using tissue oxygenation measurements 有权
    使用组织氧合测量进行休克后评估的方法和装置

    公开(公告)号：US08639332B2

    公开(公告)日：2014-01-28

    申请号：US12845830

    申请日：2010-07-29

    申请人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    发明人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    IPC分类号： A61N1/365

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a therapy delivery module coupled to the electrode to deliver a therapy via the electrode in response to the sensed cardiac signals, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the optical sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, and determine whether the delivered therapy restored cardiac hemodynamic function in response to the determined tissue oxygenation trend.

    摘要翻译： 一种用于递送治疗的方法和装置，其包括用于感测心脏信号并递送治疗的电极，治疗递送模块，其耦合到所述电极，以响应于感测到的心脏信号经由所述电极递送治疗;发射光和检测的传感器 发射由邻近光学传感器的组织体积散射的光，以产生对应的检测到的光强度输出信号;耦合到传感器的控制模块，以响应于递送治疗来控制传感器的光发射;以及耦合到治疗传递的控制器 模块和传感器，所述控制器被配置为响应于所述输出信号确定组织氧合测量，响应于所述组织氧合测量确定组织氧合趋势，并且确定所递送的治疗是否响应于所确定的组织氧合来恢复心脏血液动力学功能 趋势。

    Active noise cancellation in an optical sensor signal
    90.
    发明授权
    Active noise cancellation in an optical sensor signal 有权
    光学传感器信号中的主动噪声消除

    公开(公告)号：US08352008B2

    公开(公告)日：2013-01-08

    申请号：US12797831

    申请日：2010-06-10

    申请人： Jonathan L. Kuhn ,  David A. Anderson ,  Can Cinbis

    发明人： Jonathan L. Kuhn ,  David A. Anderson ,  Can Cinbis

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1459 ,  A61B5/1495

    摘要： A medical device system and associated method are used for monitoring tissue oxygenation. An optical sensor produces a signal corresponding to tissue light attenuation. A processor receives the optical sensor signal and computes a first measure of light attenuation at a first light wavelength and a second measure of light attenuation at a second light wavelength. In one embodiment, noise cancellation circuitry receives the first measure and the second measure and generates a guessed ratio of the first and second measures. Using the first measure, the second measure and the guessed ratio, the noise cancellation circuitry provides a peak output power when the guessed ratio corresponds to an actual ratio of the first and second measures.

    摘要翻译： 医疗器械系统和相关方法用于监测组织氧合。 光学传感器产生对应于组织光衰减的信号。 处理器接收光学传感器信号并且计算第一光波长处的光衰减的第一测量值和在第二光波长处的光衰减的第二测量值。 在一个实施例中，噪声消除电路接收第一测量和第二测量并产生第一和第二测量的猜测比率。 使用第一测量，第二测量和猜测比率，当猜测比率对应于第一和第二测量的实际比率时，噪声消除电路提供峰值输出功率。