-
公开(公告)号：US07138106B2
公开(公告)日：2006-11-21
申请号：US10161606
申请日：2002-06-05
申请人： Scott Evans , Richard J. Greff , James I. Wright
发明人： Scott Evans , Richard J. Greff , James I. Wright
CPC分类号： A61K9/0024
摘要： Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a polymer, a biocompatible solvent and a contrast agent. The polymer is selected from the group consisting of polyacrylonitrile, polyurethane, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid.
-
公开(公告)号：US07083643B2
公开(公告)日：2006-08-01
申请号：US10388741
申请日：2003-03-17
申请人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
发明人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/00491 , A61B17/12022 , A61B17/12118 , A61B17/12186 , A61B2017/00495 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2002/823 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61L24/043 , A61M25/1011 , A61M2025/1013 , A61M2025/105 , A61M2025/1086 , Y10S623/903
摘要： This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.
-
公开(公告)号：US07022318B2
公开(公告)日：2006-04-04
申请号：US10330533
申请日：2002-12-30
申请人： George Wallace , Richard J. Greff
发明人： George Wallace , Richard J. Greff
IPC分类号： A16K31/74
CPC分类号： A61K49/048 , A61K31/717 , A61K31/765 , A61K49/0002
摘要： Disclosed are methods for treating urinary incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the periurethral tissue of the mammal.
摘要翻译： 公开了用于治疗哺乳动物的尿失禁的方法，其中将包含生物相容性聚合物，生物相容性溶剂和造影剂的组合物递送至哺乳动物的尿道周围组织。
-
公开(公告)号：US06645167B1
公开(公告)日：2003-11-11
申请号：US09574500
申请日：2000-05-19
申请人： Thomas J. Whalen, II , Chinh Ngoc Tran , Douglas Ray Hayman , Noah Michael Roth , Jacques Moret , Richard J. Greff
发明人： Thomas J. Whalen, II , Chinh Ngoc Tran , Douglas Ray Hayman , Noah Michael Roth , Jacques Moret , Richard J. Greff
IPC分类号： A61F200
CPC分类号： A61K49/0419 , A61K9/0024 , A61L24/001 , A61L24/046 , A61L24/06 , A61L24/08 , A61L2430/36 , A61M5/31586 , A61M2025/1052 , C08J3/091 , C08L29/04
摘要： Disclosed are novel methods for embolizing blood vessels comprising delivering, via a catheter, an embolic composition comprising a biocompatible polymer, a biocompatible water insoluble contrast agent, and a biocompatible solvent. In one embodiment, the method is conducted during a single surgical procedure whereby a flow-arresting device is positioned and activated at the vascular site to be embolized, the embolic composition is injected, and the flow-arresting device is deactivated. In another embodiment, the method is conducted during a single surgical procedure whereby two embolic compositions, situated adjacent to one another, are injected at the vascular site to be embolized.
摘要翻译： 公开了用于栓塞血管的新颖方法，包括通过导管递送包含生物相容性聚合物，生物相容性水不溶性造影剂和生物相容性溶剂的栓塞组合物。 在一个实施方案中，该方法在单次外科手术过程中进行，由此在要栓塞的血管部位定位并激活止血装置，注射栓塞组合物，并且阻流装置停用。 在另一个实施方案中，该方法在单次外科手术过程中进行，由此彼此相邻的两个栓塞组合物被注射到待栓塞的血管部位。
-
公开(公告)号：US06565601B2
公开(公告)日：2003-05-20
申请号：US09811600
申请日：2001-03-20
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61B17/1214 , A61B17/12172 , A61B17/12186 , A61B2017/1205 , A61F2/90 , A61F2/945 , A61F2002/077 , A61F2002/30583 , A61F2210/0085 , Y10S623/903
摘要： Disclosed are methods for vascular reconstruction of diseased, non-aneurysmal arteries.
-
公开(公告)号：US06562317B2
公开(公告)日：2003-05-13
申请号：US09785274
申请日：2001-02-20
申请人： Richard J. Greff , George Wallace
发明人： Richard J. Greff , George Wallace
IPC分类号： A61K5100
CPC分类号： A61K51/06 , A61K51/1217 , A61K2121/00
摘要： Disclosed are novel radioactive compositions which are particularly suited for treating solid mass tumors via catheter delivery.
摘要翻译： 公开了特别适用于通过导管递送治疗固体肿瘤的新型放射性组合物。
-
公开(公告)号：US06555104B2
公开(公告)日：2003-04-29
申请号：US09848303
申请日：2001-05-04
申请人： George Wallace , Richard J. Greff
发明人： George Wallace , Richard J. Greff
IPC分类号： A61K3174
CPC分类号： A61K49/048 , A61K31/717 , A61K31/765 , A61K49/0002
摘要： Disclosed are methods for treating incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the periurethral tissue of a mammal.
摘要翻译： 公开了用于治疗哺乳动物中失禁的方法，其中将包含生物相容性聚合物，生物相容性溶剂和造影剂的组合物递送至哺乳动物的尿道周围组织。
-
公开(公告)号：US06241719B1
公开(公告)日：2001-06-05
申请号：US09311802
申请日：1999-05-13
申请人： George Wallace , Richard J. Greff
发明人： George Wallace , Richard J. Greff
IPC分类号： A61M3100
CPC分类号： A61F2/958 , A61F2210/0095 , A61K51/1282 , A61M2025/1086 , A61N5/1002
摘要： Disclosed are methods for the endovascular formation of a radioactive stent using a radioactive composition. These compositions are delivered to one or more vascular sites in a mammal as a fluid composition which solidifies in vivo to form a solid, coherent radioactive mass, preferably in the form or a stent. The solidified mass stents the vascular site thereby delivering the radioactivity attendant with the composition resulting in inhibition of restenosis.
摘要翻译： 公开了使用放射性组合物的放射性支架的血管内形成的方法。 这些组合物作为流体组合物递送至哺乳动物的一个或多个血管部位，其在体内固化以形成固体，相干放射性质量，优选为形式或支架。 凝固的质量支架血管部位，从而输送伴随该组合物的放射性物质，从而抑制再狭窄。
-
公开(公告)号：US06168777A
公开(公告)日：2001-01-02
申请号：US09185147
申请日：1998-11-03
申请人： Richard J. Greff , George Wallace
发明人： Richard J. Greff , George Wallace
IPC分类号： A61K5112
CPC分类号： A61K51/06 , A61K51/1217 , A61K2121/00
摘要： Disclosed are methods for treating solid mass prostate tumors in a male mammal by use of a radiation composition.
摘要翻译： 公开了通过使用辐射组合物治疗雄性哺乳动物中的固体质量前列腺肿瘤的方法。
-
90.发明授权
公开(公告)号：US6146373A
公开(公告)日：2000-11-14
申请号：US953149
申请日：1997-10-17
申请人： Andrew H. Cragg , Richard J. Greff , Robert Pecor , John Perl , Blair Walker , George Wallace
发明人： Andrew H. Cragg , Richard J. Greff , Robert Pecor , John Perl , Blair Walker , George Wallace
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B17/00491 , A61B2017/00495 , A61B2017/1205 , A61B90/39 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M25/00 , A61M25/0097
摘要： A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent. The controlled solidification of the liquid embolic composition by use of the solidification agent allows the aneurysm to be filled precisely and rapidly even when the aneurysm is located such that gravity does not cause the liquid embolic composition to flow into the aneurysm.
-
-
-
-
-
-
-
-
-
搜索结果
99 条记录 (耗时 0.038 秒)
