公开(公告)号：US4731424A

公开(公告)日：1988-03-15

申请号：US25640

申请日：1987-03-13

申请人： Teruo Fujimoto ,  Mikio Shiono ,  Osamu Watanabe ,  Koichi Ito

发明人： Teruo Fujimoto ,  Mikio Shiono ,  Osamu Watanabe ,  Koichi Ito

IPC分类号： C08F12/14 ,  C08F4/42 ,  C08F4/46 ,  C08F12/00 ,  C08F30/08

CPC分类号： C08F30/08

摘要： A process for producing an alkenylsilyl group-containing polymer compound, comprising polymerizing a vinyl monomer compound containing an alkenylsilyl group-containing styrene compound represented by General Formula (I): ##STR1## wherein R.sup.1 represents hydrogen atom, methyl group or ethyl group; R.sup.2 and R.sup.3 may be the same or different and each represent an alkyl group having 1 to 3 carbon atoms or phenyl group; and n is an integer of 0 to 4, by using an organic metallic compound as an initiator, wherein the polymerization is carried out in the presence of N-methylpyrrolidine.There can be obtained a monodisperse alkenylsilyl group-containing high molecular compound in which only the unsaturated bond in the styrene moiety of the compound of Formula (I) has been predominantly polymerized.

摘要翻译： 一种含有烯基甲硅烷基的高分子化合物的制造方法，其特征在于，使通式（I）表示的含有含烯基甲硅烷基的苯乙烯化合物的乙烯基单体化合物聚合：其中，R1表示氢原子，甲基或乙基 组; R2和R3可以相同或不同，各自表示碳原子数1〜3的烷基或苯基; n为0〜4的整数，通过使用有机金属化合物作为引发剂，其中聚合在N-甲基吡咯烷的存在下进行。 可以得到其中仅主要使式（I）化合物的苯乙烯部分中的不饱和键聚合的单分散烯基甲硅烷基的高分子化合物。

公开(公告)号：US4560679A

公开(公告)日：1985-12-24

申请号：US542439

申请日：1983-10-17

申请人： Shigeshi Toyoshima ,  Masayasu Kurono ,  Ryoichi Unno ,  Koichi Ito

发明人： Shigeshi Toyoshima ,  Masayasu Kurono ,  Ryoichi Unno ,  Koichi Ito

IPC分类号： A61K31/695 ,  A61P35/00 ,  C07F7/08 ,  C07F7/10

CPC分类号： C07F7/0812 ,  C07F7/0818

摘要： A novel organosilicon compound represented by a formula ##STR1## wherein A is methylene, carbonyl or sulfonyl group; R, R.sub.1 and R.sub.2 are alkyl group, respectively; R.sub.3 is alkyl, substituted alkyl, alkenyl, phenyl, substituted phenyl, naphthyl, substituted naphthyl, pyridyl, substituted pyridyl, furyl, substituted furyl, thienyl, substituted thienyl group or cycloalkyl group together with the substituent A; R.sub.4 is hydrogen, alkyl or alkenyl group; and R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11 and R.sub.12 are hydrogen, alkyl or substituted alkyl, respectively,a non-toxic salt thereof, a process for the preparation of said compound or salt, as well as an antitumor agent comprising as an effective agent at least one of said compound and salt.

摘要翻译： 一种由下式表示的新型有机硅化合物，其中A是亚甲基，羰基或磺酰基; R，R 1和R 2分别是烷基; R 3是烷基，取代的烷基，烯基，苯基，取代的苯基，萘基，取代的萘基，吡啶基，取代的吡啶基，呋喃基，取代的呋喃基，噻吩基，取代的噻吩基或环烷基与取代基A一起; R4是氢，烷基或烯基; R 5，R 6，R 7，R 8，R 9，R 10，R 11和R 12分别为氢，烷基或取代的烷基，其无毒盐，制备所述化合物或盐的方法，以及抗肿瘤剂 包括所述化合物和盐中的至少一种作为有效剂。

公开(公告)号：US09453000B2

公开(公告)日：2016-09-27

申请号：US12671873

申请日：2008-08-28

申请人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D471/04 ,  A61K31/437 ,  C07D487/04 ,  C07D498/04 ,  C07D403/10 ,  A61P25/28 ,  C07D403/04

CPC分类号： C07D403/10 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by Aβ, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.

公开(公告)号：US08571515B2

公开(公告)日：2013-10-29

申请号：US12398578

申请日：2009-03-05

申请人： Koichi Ito

发明人： Koichi Ito

IPC分类号： H04M11/00

CPC分类号： H04M1/72572 ,  H04M1/0214 ,  H04M1/236 ,  H04M1/274575 ,  H04M1/274583 ,  H04M2250/10 ,  H04M2250/12 ,  H04M2250/16 ,  H04M2250/60

摘要： A mobile terminal as a mobile terminal includes a storage unit which stores an action pattern record table having at least one action pattern registered preliminarily in correlation with addressee information, a control unit which obtains position information of the mobile terminal via a GPS antenna to identify the action pattern based on the position information obtained by a receiver in reference to the stored action pattern record table responding to the request for activating a redial function, and a main display which displays the addressee information in accordance with the priority of the addressee information correlated with the action pattern identified by the control unit in reference to the action pattern record table.

摘要翻译： 作为移动终端的移动终端包括存储单元，其存储具有与收件人信息相关的预先登记的至少一个动作模式的动作模式记录表，控制单元，其通过GPS天线获取移动终端的位置信息，以识别 基于由接收机参照存储的动作模式记录表响应于激活重拨功能的请求获得的位置信息的动作模式，以及主显示器，其根据与所述收件人信息相关联的收件人信息的优先级显示收件人信息 由控制单元参考动作模式记录表识别的动作模式。

公开(公告)号：US08433209B2

公开(公告)日：2013-04-30

申请号：US12960398

申请日：2010-12-03

申请人： Koichi Ito

发明人： Koichi Ito

IPC分类号： G03G15/00 ,  G06K15/00

CPC分类号： G03G15/5016 ,  G03G15/5062 ,  G03G15/5087 ,  G03G2215/00109

摘要： If a print misregistration amount on a sheet is larger than a predetermined threshold before determining whether a printed image is appropriate or not, an abnormal status of the image printed on the sheet is detected without correcting image data for inspection. A control method for controlling a detecting apparatus for inspecting a print status of an image printed on a sheet by a printing apparatus includes detecting, in a case where it is determined that a print misregistration amount of the image printed on the sheet with respect to the sheet is larger than a predetermined threshold, an abnormality of the print status of the image read by a reading unit without performing correction.

摘要翻译： 如果在确定打印图像是否合适之前纸张上的打印重合量大于预定阈值，则在不校正图像数据的情况下检测打印在纸张上的图像的异常状态。 一种用于控制检测装置的控制方法，用于检查通过打印装置打印在片材上的图像的打印状态，包括在确定打印在片材上的图像的打印重合量相对于 片材大于预定阈值，由读取单元读取的图像的打印状态的异常，而不进行校正。

公开(公告)号：US08248312B2

公开(公告)日：2012-08-21

申请号：US12551800

申请日：2009-09-01

申请人： Ning Guan ,  Koichi Ito

发明人： Ning Guan ,  Koichi Ito

IPC分类号： H01Q1/24 ,  H01Q1/36

CPC分类号： H01Q1/243 ,  H01Q1/36 ,  H01Q5/371 ,  H01Q9/42

摘要： The present invention provides an antenna that is small in size and has band frequencies corresponding to multibands, and a wireless communication apparatus including the antenna. The antenna according to the present invention has two radiation elements 12a and 12b connected to a ground plate 11 via a shorting pin. The two radiation elements 12a and 12b each have a lower arm and an upper arm that are formed through bending. The lower arm is connected to the shorting pin and is located closer to the ground plate 11 than the upper arm is. At least one of the lower arm and the upper arm has a meandered structure.

摘要翻译： 本发明提供一种尺寸小且具有对应于多个频带的频带频率的天线，以及包括该天线的无线通信装置。 根据本发明的天线具有通过短路引脚连接到接地板11的两个辐射元件12a和12b。 两个辐射元件12a和12b各自具有通过弯曲形成的下臂和上臂。 下臂连接到短路销，并且比上臂更靠近接地板11。 下臂和上臂中的至少一个具有蜿蜒的结构。

公开(公告)号：US08048878B2

公开(公告)日：2011-11-01

申请号：US12403565

申请日：2009-03-13

申请人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Mamoru Takaishi ,  Koichi Ito ,  Toshihiko Kaneko ,  Takeo Sasaki ,  Takehiko Miyagawa ,  Hiroaki Hagiwara ,  Yu Yoshida

发明人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Mamoru Takaishi ,  Koichi Ito ,  Toshihiko Kaneko ,  Takeo Sasaki ,  Takehiko Miyagawa ,  Hiroaki Hagiwara ,  Yu Yoshida

IPC分类号： C07D491/02 ,  C07D265/36 ,  C07D498/02 ,  C07D295/00 ,  A61K31/535 ,  A61K31/50 ,  A61K31/44 ,  A01N43/60

CPC分类号： C07D471/04 ,  C07D487/04

摘要： The present invention relates to a novel two cyclic cinnamide compound and a pharmaceutical agent comprising the compound as an active ingredient. The two cyclic cinnamide compound represented by the general formula (I): wherein represents a single bond or a double bond; Ar1 represents a phenyl group or pyridinyl group that may be substituted with 1 to 3 substituents; R1 and R2 each represent a C1-6 alkyl group, a hydroxyl group, or the like; Z1 represents a methylene group or vinylene group, which may be substituted with 1 or 2 substituents selected from Substituent Group A1, an oxygen atom, or an imino group that may be substituted with a substituent selected from Substituent Group A1; and p, q, and r each represent an integer of 0 to 2, which has an effect of reducing Aβ40 and Aβ42 production, and thus is particularly useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ such as Alzheimer's disease or Down's syndrome.

摘要翻译： 本发明涉及一种新型的两种环状肉桂酰胺化合物和包含该化合物作为活性成分的药剂。 由通式（I）表示的两个环状肉桂酰胺化合物：其中表示单键或双键; Ar 1表示可被1〜3个取代基取代的苯基或吡啶基; R1和R2各自表示C1-6烷基，羟基等; Z1表示亚甲基或亚乙烯基，其可以被1或2个选自取代基组A1，氧原子或可被选自取代基组A1的取代基取代的亚氨基取代基取代; p，q和r各自表示0〜2的整数，其具有降低A＆bgr 40和A＆bgr 42生成的效果，因此特别可用作由A＆bgr引起的神经变性疾病的预防或治疗剂。 如阿尔茨海默病或唐氏综合症。

公开(公告)号：US08008293B2

公开(公告)日：2011-08-30

申请号：US12522281

申请日：2008-02-27

申请人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Mamoru Takaishi ,  Koichi Ito ,  Toshihiko Kaneko ,  Takeo Sasaki ,  Nobuaki Sato ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Mamoru Takaishi ,  Koichi Ito ,  Toshihiko Kaneko ,  Takeo Sasaki ,  Nobuaki Sato ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D498/04 ,  A61K31/5375

CPC分类号： C07D498/04

摘要： The present invention relates to a compound represented by formula (I): wherein R1 represents a C1-3 alkyl group, R2 represents a hydrogen atom or a C1-3 alkyl group, Ar represents a phenyl group or the like which may be substituted with 1 to 3 substituents, X represents an oxygen atom or the like, n and m are the same or different and integers of 0 to 2, or a pharmacologically acceptable salt, and use thereof as a medicament.

摘要翻译： 本发明涉及由式（I）表示的化合物：其中R1表示C1-3烷基，R2表示氢原子或C1-3烷基，Ar表示可被基团取代的苯基等 1〜3个取代基，X表示氧原子等，n和m相同或不同，为0〜2的整数，或药理学上可接受的盐及其作为药物的用途。

公开(公告)号：US07973033B2

公开(公告)日：2011-07-05

申请号：US13005064

申请日：2011-01-12

申请人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Eriko Doi ,  Mamoru Takaishi ,  Takeo Sasaki ,  Takehiko Miyagawa ,  Hiroaki Hagiwara ,  Takashi Doko

发明人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Eriko Doi ,  Mamoru Takaishi ,  Takeo Sasaki ,  Takehiko Miyagawa ,  Hiroaki Hagiwara ,  Takashi Doko

IPC分类号： C07D471/04 ,  C07D498/04 ,  A61K31/5383 ,  A61K31/5025

CPC分类号： C07D403/10 ,  C07D471/04 ,  C07D498/04

摘要： The present invention provides a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that may be substituted with a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, which is effective as a therapeutic or prophylactic agent for a disease caused by Aβ.

公开(公告)号：US07939549B2

公开(公告)日：2011-05-10

申请号：US12395378

申请日：2009-02-27

申请人： Satoshi Nagato ,  Kohshi Ueno ,  Koki Kawano ,  Yoshihiko Norimine ,  Koichi Ito

发明人： Satoshi Nagato ,  Kohshi Ueno ,  Koki Kawano ,  Yoshihiko Norimine ,  Koichi Ito

IPC分类号： C07D401/04 ,  A61K31/44

CPC分类号： C07D213/70 ,  C07D213/64 ,  C07D213/65 ,  C07D213/69 ,  C07D213/73 ,  C07D213/74 ,  C07D213/75 ,  C07D213/76 ,  C07D213/81 ,  C07D213/84 ,  C07D213/89 ,  C07D401/04 ,  C07D401/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D471/04 ,  C07D471/06 ,  C07F7/1804

摘要： The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula —X-A (wherein X indicates a single bond, an optionally substituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).

摘要翻译： 本发明提供了具有优异的AMPA受体抑制作用和/或红藻氨酸盐抑制作用的新型化合物。 由下式表示的化合物，其盐或其水合物。 在该式中，Q表示NH，O或S; 并且R 1，R 2，R 3，R 4和R 5彼此相同或不同，各自表示氢原子，卤素原子，C 1-6烷基或由式-XA表示的基团（其中X表示单 键，任选取代的C 1-6亚烷基等; A表示任选取代的C 6-14芳族烃基环基或5至14元芳族杂环基等）。