公开(公告)号：US20190352674A1

公开(公告)日：2019-11-21

申请号：US16399145

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Cristina Serrano AMATRIAIN ,  Gary J. Smith ,  Paul Sheldon Pearlman ,  Mark Paul Taylor ,  Jonathan Combe ,  Daniel Bawdon

IPC: C12P7/04 ,  C12N1/20 ,  C12P7/06 ,  C12P7/42 ,  C12N9/10 ,  C12N9/88 ,  C12N9/04

Abstract: Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.

公开(公告)号：US20190338377A1

公开(公告)日：2019-11-07

申请号：US16398401

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Emilie Sophie FRITSCH

IPC: C12R1/38 ,  C12N9/02 ,  C12N15/68 ,  C12N15/52 ,  C12N9/14 ,  C12P7/16

Abstract: Methods of redirecting carbon flux and increasing C2/C3 or a C4/5/6 carbon chain length carbon-based chemical product yield in an organism, nonnaturally occurring organisms with redirected carbon flux and increased C2/C3 or C4/5/6 carbon chain length carbon-based chemical product yield and methods for using these organisms in production of C2/C3 or C4/5/6 carbon chain length carbon-based chemical products are provided.

公开(公告)号：US20190316072A1

公开(公告)日：2019-10-17

申请号：US16372106

申请日：2019-04-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Gary J. Smith ,  Paul S. Pearlman ,  Gregory S. Kirby

IPC: C12M1/00 ,  C12P7/62 ,  C12M1/34

Abstract: Provided herein are systems and methods for recycling and supplementing off-gas from a gas fed reaction process. The systems and methods are particularly useful for bioprocesses that convert hydrogen gas into one or more biosynthetic products. By maintaining separate hydrogen and oxygen feed gas streams, and forming a recycle gas that introduces a target component of the supply gas to the bioreactor within a target concentration range, the yields, productivities, and safety profiles of the bioprocess can be enhanced.

公开(公告)号：US20190300839A1

公开(公告)日：2019-10-03

申请号：US16372099

申请日：2019-04-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Gary J. Smith ,  Paul S. Pearlman ,  Gregory S. Kirby

IPC: C12M1/34

Abstract: The present disclosure provides methods for controlling oxygen concentration during aerobic biosynthesis, e.g., fermentation. The method may comprise feeding an oxygen-containing gas into a vessel including a fermentation feedstock and reacting the fermentation feedstock with the oxygen-containing gas to form a broth including a gaseous phase dispersed within the broth. The gaseous phase may comprise any unreacted oxygen from the oxygen-containing gas. The method further includes reducing the concentration of the unreacted oxygen in the dispersed gaseous phase to less than the limiting oxygen concentration (“LOC”) for flammability before separating the gaseous phase from the fermentation broth. The concentration of the unreacted oxygen in the gaseous phase is reduced by employing oxygen removal schemes or oxygen dilution schemes.

公开(公告)号：US20190300838A1

公开(公告)日：2019-10-03

申请号：US16372092

申请日：2019-04-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Gary J. Smith ,  Paul S. Pearlman ,  Gregory S. Kirby

IPC: C12M1/34 ,  C12M1/107 ,  C12M1/00 ,  C12M1/36

Abstract: Disclosed are materials and methods for managing aerobic biosynthesis. The materials include a fermenter system comprising a fermenter, a microorganism provided to the fermenter, and at least two control loops. The methods are directed to measuring and controlling different oxygen concentrations within the fermenter.

公开(公告)号：US10279771B2

公开(公告)日：2019-05-07

申请号：US14835307

申请日：2015-08-25

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Scott Westoby

IPC: D03D1/02 ,  B60R21/235 ,  D01D5/42 ,  B29C47/00 ,  D02G3/44 ,  D03D13/00 ,  D03D15/00 ,  B60R21/2338

Abstract: Disclosed herein is the preparation of woven fabrics suitable for use in manufacturing vehicle airbags. Such fabrics are woven from a plurality of polymeric, e.g., polyamide, warp and weft tapes which have preferably been slitted, preferably in the machine direction, from a thermoplastic polymer film, and preferably from such a film which has been drawn at least in the machine direction. The resulting fabrics exhibit both the relatively low basis weight, stiffness and small packing volume typical of nylon films, and the relatively high tear strength and high damage tolerance of yarn-based woven airbag fabrics.

公开(公告)号：US10273518B2

公开(公告)日：2019-04-30

申请号：US14908659

申请日：2014-07-29

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alex Van Eck Conradie ,  Adriana Leonora Botes

IPC: C12P19/32 ,  C12P7/40 ,  C12P7/26 ,  C12N9/10

Abstract: This document describes biochemical pathways that include the production of 3-oxopent-4-enoyl-CoA by condensation of acryloyl-CoA and acetyl-CoA using a β-ketothiolase with a SER-HIS-HIS catalytic triad. These pathways described herein rely on enzymes such as, inter alia, dehydrogenases, dehydratases and β-ketothiolases.

公开(公告)号：US10265642B2

公开(公告)日：2019-04-23

申请号：US15094770

申请日：2016-04-08

Applicant: INVISTA NORTH AMERICA S.a.r.l.

Inventor： Gary Smith ,  Gregory S Kirby ,  Paul Pearlman

IPC: B01D15/18 ,  C12P13/00 ,  C07C209/82 ,  C07C209/86 ,  C07C211/09 ,  C07C211/12 ,  C07C213/10 ,  C07C227/38 ,  C07C227/40 ,  C07C229/08

Abstract: The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.

公开(公告)号：US10196657B2

公开(公告)日：2019-02-05

申请号：US14139072

申请日：2013-12-23

Applicant: INVISTA North America S.á r.l.

Inventor： Paul S. Pearlman ,  Alex Van Eck Conradie ,  Changlin Chen ,  Adriana Leonora Botes

IPC: C12P13/00 ,  C12P7/18 ,  C12N1/20 ,  C12N15/00 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/88 ,  C07H21/04 ,  C12P7/44 ,  C12P7/42 ,  C12N15/52

Abstract: This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on enzymes or homologs accepting methyl ester shielded dicarboxylic acid substrates.

公开(公告)号：US10167593B2

公开(公告)日：2019-01-01

申请号：US14429118

申请日：2013-09-18

Applicant: INVISTA TECHNOLOGIES S.A.R.L. ,  Wae-Hai Tung ,  Ronnie Rittenhouse

Inventor： Wae-Hai Tung ,  Ronnie Rittenhouse

IPC: D06P3/28 ,  D06P3/56 ,  D06P3/38

Abstract: Disclosed are processes for application of dyes and topical chemistries to single yarns during a yarn rewind process. The process foregoes the need for downstream environmentally unfavorable dyeing and low PH chemical treatment processes on the finished carpet. Further, neutral pH dye solutions can be used instead of the prior art low pH dye solutions. The single, treated yarn can then be twisted, weaved and tufted, twisted yarn under dry conditions, and the twisted yarn subsequently weaved or weaved and tufted, into a finished fabric or carpet. Also disclosed are systems, BCF yarns, and carpets made from the BCF yarn treated by the disclosed processes.