公开(公告)号：US20040062891A1

公开(公告)日：2004-04-01

申请号：US10256612

申请日：2002-09-26

发明人： Daniel James Horn ,  Yiqun Wang ,  Victor Schoenle

IPC分类号： B32B001/08

CPC分类号： A61M25/1036 ,  A61M25/0045 ,  A61M25/10 ,  A61M25/1006 ,  A61M2025/018 ,  Y10T29/49826 ,  Y10T29/49863 ,  Y10T29/49865 ,  Y10T428/13 ,  Y10T428/1334 ,  Y10T428/1345 ,  Y10T428/1352 ,  Y10T428/139 ,  Y10T428/1393

摘要： Sheath materials and processes are disclosed. For example, hypotube sheaths and processes of making hypotube sheaths are disclosed. Devices and systems, including medical devices and systems, such as catheters, containing hypotube sheaths are also disclosed.

摘要翻译： 披露了护套材料和工艺。 例如，披露了海波鞘和制造海波鞘的方法。 还公开了包含医疗装置和系统的装置和系统，例如包含海波鞘的导管。

公开(公告)号：US20040062890A1

公开(公告)日：2004-04-01

申请号：US10255487

申请日：2002-09-26

发明人： Edwin Wang ,  Florencia Lim ,  Huong Chung ,  Chi Le Long ,  Ni Ding

IPC分类号： B29D022/00

CPC分类号： A61M25/1034 ,  A61M25/10 ,  A61M25/1006 ,  A61M2025/1075 ,  Y10T428/1334

摘要： A balloon catheter and a method of making the balloon catheter, having a balloon which is bonded to an elongated shaft, and which has a first layer and a second layer and an improved strong bond between the balloon and the shaft. One aspect of the invention is directed to a balloon in which the balloon first layer has at least a section with a gas plasma-etched or chemical solution-etched surface for improved bondability. Another aspect of the invention is directed to a balloon in which the balloon first layer has a proximal end section bonded to an outer surface of the shaft and the balloon second layer has a proximal end section bonded to an inner surface of the shaft, and, in one embodiment, at least a section of the balloon first layer has a gas plasma-etched or chemical solution-etched surface.

摘要翻译： 气囊导管和制造气囊导管的方法，具有结合到细长轴的气球，并且具有第一层和第二层以及在球囊和轴之间改善的强结合。 本发明的一个方面涉及一种球囊，其中球囊第一层具有至少一个具有气体等离子体蚀刻或化学溶液蚀刻表面的部分，以提高粘合性。 本发明的另一方面涉及一种球囊，其中球囊第一层具有接合到轴的外表面的近端部分，球囊第二层具有接合到轴的内表面的近端部分， 在一个实施例中，球囊第一层的至少一部分具有气体等离子体蚀刻或化学溶液蚀刻表面。

公开(公告)号：US20030236495A1

公开(公告)日：2003-12-25

申请号：US10436452

申请日：2003-05-12

发明人： Kenneth C. Kennedy II

IPC分类号： A61M029/00

CPC分类号： A61M25/10 ,  A61M25/1006 ,  A61M2025/1004 ,  A61M2025/1068

摘要： A balloon catheter including an inflatable balloon affixed to a catheter. The proximal end of the balloon is affixed to the outer wall of the catheter so as to provide an air tight seal there between. A slip joint is formed between the distal end of the catheter and the distal end of the balloon to permit the distal end of the balloon to axially move or translate with respect to the distal end of the catheter. The slip joint allows the axial length of balloon to change during inflation or deflation without transferring tensile or compressive forces between the balloon and the catheter, thereby preventing transverse creases from forming in the surface of the balloon and preventing the catheter from bowing. Alternatively, the catheter may be terminated so as to not contact the distal end of the balloon, or the catheter can be segmented so that separate catheter parts are connected to each end of the balloon, thereby eliminating the slip joint altogether.

摘要翻译： 气囊导管，其包括固定在导管上的可膨胀气囊。 气囊的近端固定在导管的外壁上，以便在其间提供气密密封。 在导管的远端和球囊的远端之间形成滑动关节，以允许气囊的远端相对于导管的远端轴向移动或平移。 滑动接头允许气囊的轴向长度在充气或放气期间改变，而不会在气囊和导管之间传递拉伸或压缩力，从而防止在球囊表面形成横向折痕并防止导管弯曲。 或者，导管可以被终止以不接触球囊的远端，或者可以将导管分段，使得单独的导管部分连接到球囊的每个端部，从而完全消除滑动关节。

公开(公告)号：US20030180488A1

公开(公告)日：2003-09-25

申请号：US10103274

申请日：2002-03-21

发明人： Florencia Lim ,  Chi Le Long ,  Charles D. Claude ,  Jeong S. Lee ,  Srinivasan Sridharan ,  Fernando Gonzalez ,  Edwin Wang

IPC分类号： B32B001/02

CPC分类号： A61M25/1034 ,  A61L29/041 ,  A61L29/085 ,  A61L29/126 ,  A61M25/1006 ,  A61M25/1025 ,  A61M25/1029 ,  A61M2025/1075 ,  Y10T428/13 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1376 ,  Y10T428/1386 ,  Y10T428/139 ,  Y10T428/1393 ,  C08L27/18

摘要： A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is an elastomer selected from the group consisting of a silicone-polyurethane copolymer and a diene polymer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set, to provide improved balloon performance. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.

摘要翻译： 由诸如膨胀聚四氟乙烯（ePTFE）的聚合物材料形成的导管球囊结合到由低拉伸凝固聚合物形成的第二层和/或用低拉伸固化聚合物浸渍。 在目前优选的实施方案中，低拉伸固化聚合物是选自硅氧烷 - 聚氨酯共聚物和二烯聚合物的弹性体。 低强度聚合物具有高强度，低模量，高伸长率和低拉伸强度，以提供改进的球囊性能。 二烯或硅氧烷聚氨酯具有低拉伸组合，其有利于将气囊放气至低剖面放气构型。 本发明的一个方面提供了改进的二烯与ePTFE的连接。 在一个实施方案中，第二层由与二烯混合的二烯混合形成，所述二烯与粘合促进剂例如硫化剂混合。

公开(公告)号：US20030083538A1

公开(公告)日：2003-05-01

申请号：US10003910

申请日：2001-11-01

申请人： Cardiac Dimensions, Inc.

发明人： John M. Adams ,  David G. Reuter ,  Mark L. Mathis ,  Scott J. Wolf

IPC分类号： A61N001/36

CPC分类号： A61F2/2451 ,  A61M25/1006

摘要： A mitral valve therapy device and method treats dilated cardiomyopathy. The device is configured to be placed in the coronary sinus of a heart adjacent to the mitral valve annulus. The device includes a force distributor that distributes an applied force along a pericardial wall of the coronary sinus, and a force applier that applies the applied force to one or more discrete portions of a wall of the coronary sinus adjacent to the mitral valve annulus to reshape the mitral valve annulus in a localized manner.

公开(公告)号：US06551272B2

公开(公告)日：2003-04-22

申请号：US09254429

申请日：1999-08-10

申请人： Fred G. Göbel

发明人： Fred G. Göbel

IPC分类号： A61M3700

CPC分类号： A61M25/10 ,  A61J15/0003 ,  A61J15/0049 ,  A61J15/0073 ,  A61J15/0088 ,  A61M16/04 ,  A61M16/0415 ,  A61M16/0438 ,  A61M16/0459 ,  A61M16/0465 ,  A61M25/1006 ,  A61M2016/0027 ,  A61M2025/1004

摘要： The invention is based on the intention of creating a stomach probe with which a watertight closure of the oesophagus is possible. The stomach probe, according to the invention, is characterized by a tampon-bladder for watertight closure of the oesophagus, in which the tampon-bladder forms from flexible and/or elastic material at least a closed inner cavity for the reception of a fluid medium, through a means (11) of establishing a prescribed pressure for the medium in the tampon-bladder (16) by an inner lumen forming the actual stomach probe, from which an outer hose-like lumen (18) extending to the tampon-bladder (16) is so arranged that between the outer lumen (18) and the inner lumen (17) a channel is formed connected to the inner cavity of the tampon-bladder (16) arranged on the outer lumen (18) by a number of openings (20), whereby the inner cavity of the tampon-bladder (16) is connected via the canal formed between the inner and outer lumina (17, 18) with the means of production of pressure in the tampon-bladder, that is, with a suitably graded reservoir or equalizing vessel (11) for the liquid medium situated above the tampon-bladder and outside the patient.

摘要翻译： 本发明基于创建胃探针的目的，通过该胃探针可以进行​​食管的水密闭合。 根据本发明的胃探针的特征在于用于水密封闭食管的棉塞 - 囊，其中棉塞从弹性和/或弹性材料形成至少一个封闭的内腔，用于接收流体介质 通过形成实际胃探头的内腔为棉塞 - 囊（16）中的介质建立规定压力的装置（11），从软管状腔（18）延伸到卫生棉条 （16）布置成在所述外腔（18）和所述内腔（17）之间形成有通道，所述通道与布置在所述外腔（18）上的所述止血塞（16）的内腔连接，多个 开口（20），由此棉塞 - 囊（16）的内腔经由形成在内腔和外腔（17,18）之间的管道与在棉塞中产生压力的装置相连， 具有用于液体介质的适当分级的储存器或均衡容器（11） 在棉塞膀胱上方和患者外面。

公开(公告)号：US20030009190A1

公开(公告)日：2003-01-09

申请号：US10163077

申请日：2002-06-04

发明人： Harold D. Kletschka ,  Brian Packard

IPC分类号： A61M029/00

CPC分类号： A61M25/1011 ,  A61B17/22032 ,  A61B17/221 ,  A61B2017/00526 ,  A61B2017/22001 ,  A61B2017/22051 ,  A61B2017/2212 ,  A61F2/013 ,  A61F2/848 ,  A61F2002/8483 ,  A61M25/0029 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/1002 ,  A61M25/1006 ,  A61M25/104 ,  A61M29/02 ,  A61M2025/0039 ,  A61M2025/004 ,  A61M2025/0079 ,  A61M2025/091 ,  A61M2025/09125 ,  A61M2025/1015 ,  A61M2025/109 ,  A61M2025/1093

摘要： An angioplasty device and particle trap for use in removal of a particle from a small diameter vessel or vessel-like structure is disclosed. One embodiment includes a catheter for insertion into a vessel-like structure, the catheter having a catheter wall and a movable member, a trap operably connected to the catheter wall and to the movable member, wherein relative motion between the catheter wall and the movable member actuates the trap. In one embodiment, the expanded trap is formed from struts in a spiral-shaped configuration. In one embodiment, the contracted trap forms a waist to creates a pinch-point to trap particles. In one embodiment, the contracted trap forms a cocoon-like structure to further trap particles. In one embodiment, the angioplasty device includes a handle to actuate the trap from a contracted position to an expanded position and return to a contracted position. The handle provides rotational or longitudinal or both types of movement to actuate the trap.

摘要翻译： 公开了一种用于从小直径容器或容器状结构去除颗粒的血管成形术装置和颗粒捕集器。 一个实施例包括用于插入血管状结构的导管，所述导管具有导管壁和可移动构件，可操作地连接到导管壁和可移动构件的捕集器，其中导管壁和可动构件之间的相对运动 启动陷阱。 在一个实施例中，膨胀的捕集器由螺旋状构造的支柱形成。 在一个实施例中，收缩的陷阱形成腰部以产生捕获颗粒的夹点。 在一个实施方案中，收缩阱形成茧状结构以进一步捕获颗粒。 在一个实施例中，血管成形术装置包括手柄，以将收集器从收缩位置致动到扩张位置并返回收缩位置。 手柄提供旋转或纵向或两种类型的运动以致动捕获器。

公开(公告)号：US20020188312A1

公开(公告)日：2002-12-12

申请号：US09881080

申请日：2001-06-12

发明人： Terry Guinan ,  John Connolly ,  Pat Duane ,  Donagh O'Shaughnessy ,  Michael Bannon

IPC分类号： A61M029/00

CPC分类号： A61M25/1006 ,  A61M2025/0081 ,  A61M2025/0183 ,  A61M2025/1013

摘要： The present invention is a catheter having an elongated tubular member having a proximal and a distal end. A balloon is positioned at the distal end of the tubular member. A guidewire tubular member extends from a position proximal the balloon through the balloon to a position distal the balloon, the guidewire tubular member has a proximal segment having a first flexibility and a distal segment having a second flexibility. The distal segment is more flexible than the proximal segment. A bond joins the balloon distal end to the proximal segment and the distal segment.

摘要翻译： 本发明是具有细长管状构件的导管，其具有近端和远端。 气囊位于管状构件的远端。 导丝管状构件从靠近球囊的位置延伸穿过球囊到远离球囊的位置，导丝管状构件具有具有第一柔性的近侧段和具有第二柔性的远端段。 远端段比近端段更灵活。 粘合剂将气囊远端连接到近端段和远端段。

公开(公告)号：US06306074B1

公开(公告)日：2001-10-23

申请号：US09304783

申请日：1999-05-04

申请人： Ron Waksman ,  Thomas D. Weldon ,  Raphael F. Meloul ,  Richard A. Hillstead ,  Jonathan J. Rosen ,  George K. Bonnoitt, Jr. ,  David S. Halpern ,  Charles E. Larsen ,  Ian R. Crocker

发明人： Ron Waksman ,  Thomas D. Weldon ,  Raphael F. Meloul ,  Richard A. Hillstead ,  Jonathan J. Rosen ,  George K. Bonnoitt, Jr. ,  David S. Halpern ,  Charles E. Larsen ,  Ian R. Crocker

IPC分类号： A61M2902

CPC分类号： A61M37/0069 ,  A61M25/0029 ,  A61M25/1002 ,  A61M25/1006 ,  A61M2025/0037 ,  A61M2025/0039 ,  A61M2025/004 ,  A61N5/1002 ,  A61N5/1007 ,  A61N2005/1003 ,  A61N2005/1005 ,  A61N2005/1008 ,  A61N2005/1023

摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

摘要翻译： 描述了用于将治疗元件（例如辐射源）通过导管递送到患者（例如冠状动脉）的管腔内通道中用于抑制形成瘢痕组织的可能发生的装置和方法 在球囊血管成形术后再狭窄。 该装置包括细长的柔性导管，其具有近端部分和远端部分，其间具有内腔，并且其直径足够小以插入病人的管腔内通道。 一个或多个处理元件，例如包含放射性物质的胶囊或丸粒，可定位在内腔内并且在液体流过内腔的力的作用下在近端部分和远端部分之间移动。 公开了一种使用这种装置的方法，包括与球囊血管成形术程序同时使用这种装置的方法。

公开(公告)号：US06179856B2

公开(公告)日：2001-01-30

申请号：US08994697

申请日：1997-12-19

申请人： Michael D. Barbere

发明人： Michael D. Barbere

IPC分类号： A61M2510

CPC分类号： A61M25/104 ,  A61M25/1006 ,  A61M25/1027 ,  A61M2025/0003 ,  A61M2025/0004 ,  A61M2025/0079

摘要： A balloon dilatation catheter used for percutaneous transluminal coronary angioplasty includes a coaxial construction of an inner tube and an outer tube. The inner tube extends distally beyond the distal end of the outer tube. A dilatation balloon is mounted on the distal end of the catheter and is connected at its proximal end to the distal end of the outer tube and at its distal end to the distal end of the inner tube. The lumen of the inner tube is adapted to receive a guidewire and may permit pressure monitoring and liquid infusion. The annular inflation lumen is defined between the inner and outer tubes. The distal end of the outer tube extends into the balloon and is anchored directly to the inner tube. The balloon may be inflated and deflated through an annular inflation lumen defined between the inner and outer tubes, there being openings in the outer tube within the balloon to communicate the inflation lumen with the interior of the balloon. The catheter displays increased column strength and resistance to axial buckling and balloon bunching by reason of the secure connection between the distal end of the outer tube and the inner tube.

摘要翻译： 用于经皮腔内冠状动脉成形术的球囊扩张导管包括内管和外管的同轴结构。 内管向远侧延伸超过外管的远端。 扩张气球安装在导管的远端，并且在其近端处连接到外管的远端，并且其远端连接到内管的远端。 内管的管腔适于接收导丝，并且可以允许压力监测和液体输注。 环形膨胀腔限定在内管和外管之间。 外管的远端延伸到气囊中并且被直接锚定到内管。 气囊可以通过限定在内管和外管之间的环形膨胀腔膨胀和放气，在气囊内的外管中有开口，以将充气腔与气囊的内部连通。 由于外管的远端和内管之间的牢固连接，导管显示出增加的柱强度和抗轴向屈曲和气球聚束。